Triptamine

Applications Antibacterial agent.
References Gribble, G.W., et al.: J. Med. Chem., 31, 1746 (1988), Maeda, U., et al.: Phytochemistry, 34, 1633 (1993),

Stability Hygroscopic
Applications N,N-Diethyltryptamine Hydrochloride is a derivative of Tryptamine (T894600). Tryptamine is a monoamine alkaloid found in plants and is commonly used in the preparation of biologically active compounds such as neurotransmitters and psychedelics.

Applications A metabolite of Zolmitriptan (Z639000).
References Buckingham, J., et al.: J. Med. Chem., 38, 3566 (1995),

Applications 9,10-Dihydroergocristine Methanesulfonate is an nontoxic and well tolerated drug that exerts agonistic and antagonistic activity on dopaminergic and adrenergic receptors. 9,10-Dihydroergocristine Methanesulfonate is known to exhibit protective properties to the brain against metabolic effects of ischemia by acting at a cellular level.
References Setti, M., et al.: Angiologia., 30, 98 (1978); Brunhofer, G., et al.: Bioorg. Med. Chem., 20, 6669 (2012); Benzi, G., et al.: Neurobiol. Aging., 9, 371 (1988);

Applications A metabolite of Tryptophan. 5-Hydroxytryptophan (5-HTP) is a direct 5-hydroxytryptamine (5-HT) precursor used to assess central serotonergic function.
References Gartside, S., et al.: Eur. J. Pharmacol., 179, 103 (1990), Gijsman, H., et al.: J. Clin. Psychopharmacol., 22, 183 (2002), Schruers, K., et al.: Psychiatry Res., 113, 237 (2002),

Impurity Melatonin USP Related Compound A
Applications A tryptamine derivative that is closely related to the neurotransmitter Melatonin (M215000) and Serotonin (S274980). It acts as a full agonist at the 5-HT1, 5-HT2, 5-HT4, 5-HT6, and 5-HT7 receptors but has no affinity for the 5-HT3 receptor (1,2,3,4). Melatonin USP Related Compound A.
References (1) Yamada, J. et al.: Eur. J. Pharmacol., 323, 235 (1997)(2) Craig, D.A. et al.: NAun. Schmied. Arch. Pharmacol., 342, 9 (1990) (3) Hemedah, M. et al.: Br. J. Pharmacol., 126, 179 (1999)(4) Millan-Plano, S. et al.: Int. J. Mol. Sci., 11, 312 (2010)

Applications α-Methyltryptamine is a methylated Tryptamine with psychedelic, stimulant and entactogenic properties. α-Methyltryptamine is a non-selective serotonin receptor agonist. α-Methyltryptamine acts as relatively balanced releasing agent of serotonin, norepinephrine, and dopamine.
References Nagain, F. et al.: Eur. J. Pharmacol., 559, 132 (2007); Nonaka, R. et al.: Biol. Pharmac. Bull., 30, 2328 (2007);

Applications Buspirone EP Impurity J is a derivative compound of Buspirone Hydrochloride (B689850), a non-benzodiazepine anxiolytic; 5-hydroxytryptamine (5-HT1) receptor agonist.
References Wu, Y. H., et al.: J. Med. Chem., 15, 477 (1972), Allen, L. E., et al.: Arzneim.-Forsch., 24, 917 (1974), Goa, K. L., et al.: Drugs, 32, 114 (1986),

Stability Hygroscopic
Applications A metabolite of Melatonin (M215000).
References Reiter, R.J., et al.: J. Biomed. Sci., 7, 444 (2000), Chen, Z., et al.: Am. J. Physiol, 284, 1618 (2003), Barrenetxe, J., et al.: J. Physiol. Biochem., 60, 61 (2004),

Applications Fluoxetine is a 5-hydroxytryptamine reuptake inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Impurity Zolmitriptan USP Related Compound E
Applications A metabolite of Zolmitriptan. Zolmitriptan USP Related Compound E.
References Forrester, L., et al.: Biochem. J., 281, 359 (1992), Newton, D., et al.: Drug Metab. Dis., 23, 154 (1995), Dixon, R., et al.: Clin. Drug Invest., 15, 515 (1998), Whale, R., et al.: Psychopharmacology, 145, 223 (1999), Wild, M., et al.: Xenobiotica, 29, 847 (1999),

Applications 5-​(Phenylmethoxy)​-1H-​indole-​3-​ethan-​α,​α,​β,​β-​d4-​ol is an intermediate in synthesizing 5-Hydroxy Tryptophol-d4 β-D-Glucuronide (H976012), a labelled metabolite of 5-Hydroxytryptamine (H974990).
References Tyce, G.M. et al.: Am. J. Physiol., 215, 611 (1969); Kveder, S., et al.: Biochem. J., 85, 447 (1962); Iskric, S., et al.: Anal. Biochem., 7, 297 (1964);

Applications A labelled metabolite of Zolmitriptan.
References Forrester, L., et al.: Biochem. J., 281, 359 (1992), Newton, D., et al.: Drug Metab. Dis., 23, 154 (1995), Dixon, R., et al.: Clin. Drug Invest., 15, 515 (1998), Whale, R., et al.: Psychopharmacology, 145, 223 (1999), Wild, M., et al.: Xenobiotica, 29, 847 (1999),

Applications 6,10-Dihydroxy Buspirone is an Impurity formed during the preparation of Buspirone metabolites. Also, it is derived from Buspirone (B689855), which is a non-benzodiazepine anxiolytic; 5-hydroxytryptamine (5-HT1) receptor agonist.
References Wu, Y.H., et al.: J. Med. Chem., 15, 477 (1972); Allen, L.E., et al.: Arzneim.-Forsch., 24, 917 (1974); Goa, K.L., et al.: Drugs, 32, 114 (1986);

Applications A labelled metabolite of Rizatriptan.
References Dechant, K., et al.: Drugs, 43, 776 (1992), Castro, J., et al.: Bioorg. Med. Chem. Lett., 3, 993 (1993), Lee, Y., et al.: Biopharm. Drug Dispos., 19, 577 (1998), Chen, J., et al.: J. Pharm. Biomed. Anal., 35, 639 (2004),

Applications N-Acetyl-d3-5-methoxytryptamine (CAS# 90735-69-6) is a useful isotopically labeled research compound that can be used to treat melatonin related conditions. It can be used in preparation with gas chromatography-mass spectroscopy analysis.
References Hillgenberg, M., et.al., PCT Int. Appl., 31, (2006); Young, I., et.al., Biomedical Mass, 12, 319-337,(1985);

Applications Tryptamine-alpha,alpha-d2 HCl (CAS# 362049-49-8) is a useful isotopically labeled research compound.