Prodotti biochimici e reagenti

<p>Nintedanib is an anti-inflammatory and anti-cancer drug. It is used for treatment of idiopathic pulmonary fibrosis. Nintedanib is a prodrug that is rapidly converted to the active form nintedanib, which inhibits angiogenesis by interfering with the activation of vascular endothelial growth factor receptor 1 (VEGFR1). <br>Nintedanib is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&amp;D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.</p>

Pimara-8(14),15-diene is an α-pinene, a hydroxy group, and an isopropyl group. It has the ability to inhibit the biosynthesis of terpenes in fungi and bacteria. This inhibits the response pathways in these cells, preventing them from synthesizing secondary metabolites such as fatty acids and monoterpene hydrocarbons. The effective dose for pimara-8(14),15-diene is 0.3 μg/mL. Pimara-8(14),15-diene is most often found in extracts of plants that have been treated with methyl chloride or ethyl ether, such as trichophyton mentagrophytes or terpene synthase enzymes.

<p>Please enquire for more information about Biotinyl-Gly-Gly-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Fmoc-Lys(Alloc)-Wang Resin (100-200 mesh) is a research tool that is used in the study of protein interactions. It has been shown to be an effective inhibitor for ion channels and cell biology. This resin can also be used to identify ligands and receptors, as well as their binding affinities. Fmoc-Lys(Alloc)-Wang Resin (100-200 mesh) is a high purity product that can be used in pharmacology and peptide synthesis.</p>

<p>C.I.Reactive Orange 84 is an amide, which is a molecule containing both an amine and a carboxylic acid functional group. This compound has been used in microscopy as a reactive dye to study surface methodology and the optimum concentration of potassium phosphate, which activated the dye. The compound has also been used to determine the activity test of wastewater, or the removal of metal hydroxides by means of photocatalytic activity. C.I.Reactive Orange 84 has shown efficient kinetic properties with respect to other dyes in that it can be used for kinetic studies at neutral pH and at low concentrations.<br>C.I.Reactive Orange 84 has also been identified as being reactive with intermolecular hydrogen bonding, which gives it the ability to bind to metal ions such as zinc and copper; this property may have implications in the development of new methods for removing metals from wastewater streams using photocatalysis.br&gt;br&gt;</p>

<p>H-VGTEDIPSK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-VGTEDIPSK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-VGTEDIPSK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-VGTEDIPSK-OH at the technical inquiry form on this page</p>

<p>This peptide is a fragment of the human coagulation factor XII. It has been shown to activate protease-activated receptor 1 (PAR1) in vitro and in vivo, which may contribute to its blood-pressure lowering effects. This peptide also reduces the risk of cardiovascular events by strengthening the endothelium and preventing oxidative stress.</p>

<p>H-Thr(tBu)-2-ClTrt-Resin (100-200 mesh) 1% DVB is a resin for peptide synthesis. It is used to immobilize amino acids, thiols, and other building blocks in order to synthesize peptides. This resin can be used for a variety of applications, including the synthesis of small organic molecules, oligonucleotides, and polysaccharides. H-Thr(tBu)-2-ClTrt-Resin (100-200 mesh) 1% DVB has been shown to react with amines and thiols.</p>

CLEAR-Base Resin (HCl) is a high-purity resin that has been used in the study of protein interactions, such as receptor and ligand binding. CLEAR-Base Resin (HCl) is also an inhibitor that can be used to block ion channels.

<p>Pigment Red 32 is an organic pigment that is soluble in propylene glycol and surface-active agents. It has a particle diameter of about 0.1 microns and an average particle size of 0.2 microns, with a maximum of 100% dispersion in water. Pigment Red 32 has been shown to be acidic, fluorescent, thiophosphoric, non-polar, styrene-based, and organic solvent-soluble. This pigment is used in the production of plastics and paints for devices such as TV screens due to its ability to liquefy under radiation or heat. Pigment Red 32 also contains functional groups that impart both hydrophobic and hydrophilic properties to the molecule.br&gt;br&gt;<br>Pigment Red 32 can be found in paint products including acrylics, alkyds, latexes, oil paints, and watercolors.br&gt;br&gt;<br>Pigment Red 32 can be found in plastics products including ABS res</p>

<p>Glucagon, human recombinant is a protein that is used to treat low blood sugar levels in people with diabetes. It is a hormone that triggers the release of glucose from the liver and other stored sources of energy. Glucagon, human recombinant can be reconstituted with sterile water for injection and then freeze-dried. This product is calibrated to contain 1 mg of glucagon per milliliter (1 mg/mL) with an n-terminal amino acid sequence that has been determined by Edman degradation to be methionine, valine, threonine, alanine, glutamic acid, proline, lysine and serine. Glucagon, human recombinant is prepared in a chromatographic purification process that utilizes dna replication and biochemical assays for quality control.br&gt;<br>Glucagon, human recombinant is used to treat low blood sugar levels in people with diabetes. It should not be used to treat type 1</p>

<p>A potent inhibitor of EGFR with sensitizing and T790M resistance mutations, selective over the wild-type form of the receptor. Causes tumour regression in EGFR mutant T790M transgenic and xenograft models in vivo.</p>

<p>The multi-functional cyclin-dependent kinase (CDK) inhibitor p21, also known as p21WAF1/Cip1 or CDKN1A functions as a cell cycle inhibitor and anti-proliferative effector. Upon DNA damage and genotoxic stress, the tumour suppressor p53 is activated and induces the expression of p21. p21 has also been implicated in nucleotide excision repair (NER), base excision repair (BER) and DNA translesion synthesis (TLS) by disrupting the proliferating cell nuclear antigen (PCNA) interaction with other DNA repair factors and promoting PCNA degradation.</p>

<p>GPX1 is a monoclonal antibody that recognizes the protein GPx-1, which is involved in the protection of cells against oxidative stress. The antibody can be used as a research tool to study GPx-1 interactions with ions, proteins and receptors. It also has potential therapeutic applications.</p>

Please enquire for more information about C.I.Basic Yellow 96 including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>C.I. Direct Red 89 is a water-soluble dye that belongs to the group of organic compounds called sulfonated naphthol dyes. It has an absorption spectrum in the region of 540-580 nm and is used as a neutral red dye for inkjet and recording applications, as well as for textile printing. C.I. Direct Red 89 can be used with other dyes for pigments, especially blue, green, and violet dyes, to produce a wide range of colors from yellow through green to blue-green. The dye is also used in pharmaceuticals, cosmetics, food coloring agents, and industrial paints.</p>

<p>H-VGTEDIPSKINLK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-VGTEDIPSKINLK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-VGTEDIPSKINLK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-VGTEDIPSKINLK-OH at the technical inquiry form on this page</p>

<p>GLG1</p>

<p>Hemoglobin A0 Mouse Monoclonal Antibody is a life science tool for use in pharmaceutical and diagnostic applications. Please enquire for more information about Hemoglobin A0 Mouse Monoclonal Antibody including the price, delivery time and more detailed product information at the technical inquiry form on this page.</p>

3-(4-[[3-(4-Chloro-2-fluorophenyl)-5-(trifluoromethyl)isothiazol-4-yl]methoxy]-3,5-difluorophenyl)propanoic acid is an antibody that is used to study the interactions between proteins in the cell. It can be used to determine the function of ion channels, protein synthesis and cell division. 3-(4-[[3-(4-Chloro-2-fluorophenyl)-5-(trifluoromethyl)isothiazol-4-yl]methoxy]-3,5-difluorophenyl)propanoic acid is a high purity reagent for research use only. This antibody has been shown to bind to a receptor of interest with high affinity and specificity. The molecular weight of this antibody is approximately 150 kDa. CAS No. 1628448-77-

Ferritin Light Chain, Recombinant is a life science tool for use in IVD applications. Please enquire for more information about Ferritin Light Chain, Recombinant including the price, delivery time and more detailed product information at the technical inquiry form on this page.

<p>1 mg/mL concentration; for use in immunoassays</p>

<p>Rho GTPase Activating Protein 26 (ARHGAP26) is a rho family negative regulator, used to convert G proteins RhoA and Cdc42 into their inactive forms. It can exist in multiple forms, with ARHGAP10 being a paralog gene of particular significance. As a type of GTPase-activating protein, ARHGAP26 has the capacity to enhance hydrolysis of GTPases, converting them from an active to an inactive form, therefore inhibiting signal transduction.This type of protein plays an important role in regulation of the behaviour of cancer cells, this occurs through ARHGAP26 being a GTPase-activating protein, meaning it can inhibit Rho-GTPases by promoting their hydrolytic ability. ARHGAP26 can also have an affect on tumorigenesis and tumour progression, by forming abnormal fusion genes, tumour development and progression can be both slowed down or sped up by ARHGAP. Understanding the molecular mechanisms of ARHGAP26 could help unearth its potential clinical value in cancer treatments.</p>

<p>Anti-PYY antibody</p>

<p>H-HPAAPSSW-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-HPAAPSSW-OH is provided at greater that &gt;98% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-HPAAPSSW-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-HPAAPSSW-OH at the technical inquiry form on this page</p>

<p>SSB, Recombinant is a life science tool for use in pharmaceutical and diagnostic applications. Please enquire for more information about SSB, Recombinant including the price, delivery time and more detailed product information at the technical inquiry form on this page.</p>

TSH Mouse Monoclonal Antibody is a life science tool for use in IVD applications. Please enquire for more information about TSH Mouse Monoclonal Antibody including the price, delivery time and more detailed product information at the technical inquiry form on this page.

<p>IsoDTB (Isotopically labeled Desthoibiotin Azide) probes take advantage of the mass shift of stable heavy isotope labels (SHLs) to enable mass-independent chemical proteomics platform that helps to address unique challenges of the proteome characterization. In this approach a unique isotopic signature is embedded exclusively into the peptides and it serves as a computationally recognizable full-scan MS reporter. By using desthiobiotin, these probes circumvented the need to use cleavable linkers for peptide elution and thus simplifies the chemoproteomic protocol, while allowing quantification of the proteome. IsoTDB pack contains 2 mg of light (IsoDTB-L) and heave (IsoDTB) probe.</p>

<p>Eletriptan is a triptan drug used for the treatment of migraines. This drug is an agonist of serotonin receptors, mainly 5-HT 1B/D. It acts to relieve migraines by causing vasoconstriction in intracranial blood vessels.</p>

<p>Toxoplasma Gondii GRA-ROP-SAG Antigen, Recombinant is a life science tool for use in pharmaceutical and diagnostic applications. Please enquire for more information about Toxoplasma Gondii GRA-ROP-SAG Antigen, Recombinant including the price, delivery time and more detailed product information at the technical inquiry form on this page.</p>

<p>Norovirus GI Mouse Monoclonal Antibody is a life science tool for use in pharmaceutical and diagnostic applications. Please enquire for more information about Norovirus GI Mouse Monoclonal Antibody including the price, delivery time and more detailed product information at the technical inquiry form on this page.</p>

<p>Ac-LSDTVNKSDLNEDGTC-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. Ac-LSDTVNKSDLNEDGTC-NH2 is provided at greater that &gt;85% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer Ac-LSDTVNKSDLNEDGTC-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about Ac-LSDTVNKSDLNEDGTC-NH2 at the technical inquiry form on this page</p>

<p>H-YDTPTLSVHPGPEVISGEKV-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-YDTPTLSVHPGPEVISGEKV-OH is provided at greater that &gt;90% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-YDTPTLSVHPGPEVISGEKV-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-YDTPTLSVHPGPEVISGEKV-OH at the technical inquiry form on this page</p>

<p>FP prostaglandin receptor agonist</p>

<p>Adenovirus Mouse Monoclonal Antibody is a life science tool for use in pharmaceutical and diagnostic applications. Please enquire for more information about Adenovirus Mouse Monoclonal Antibody including the price, delivery time and more detailed product information at the technical inquiry form on this page.</p>

<p>H-RSTSHTSDFNPNSGSDQRVV-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-RSTSHTSDFNPNSGSDQRVV-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-RSTSHTSDFNPNSGSDQRVV-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-RSTSHTSDFNPNSGSDQRVV-OH at the technical inquiry form on this page</p>

<p>A reversible and selective inhibitor of thrombin that rapidly binds to the catalytic site directly. Inhibits both soluble and bound forms of thrombin. Used for prophylaxis and treatment of heparin-induced thrombocytopenia type II.</p>

<p>Peptide Ac-KKRYDREFLLGFQF-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-VNSV^IEK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Vegfb</p>

<p>H-PPAYEKLSAEQSPPP-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-PPAYEKLSAEQSPPP-OH is provided at greater that &gt;90% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-PPAYEKLSAEQSPPP-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-PPAYEKLSAEQSPPP-OH at the technical inquiry form on this page</p>

<p>Soluble guanylate cyclases (sGCs) are heterodimeric enzymes that convert GTP to 3',5'-cyclic GMP and pyrophosphate. Most complexes consist of an alpha subunit, such as alpha-2 (GUCY1A2), and a beta subunit, typically beta-1 (GUCY1B3). In the presence of magnesium or manganese ions, enzyme activity is stimulated by nitric oxide._x000D_<br>_x000D_<br>sGCs are the principal receptors for nitric oxide (NO) and NO-releasing drugs. sGC plays a role in several cardiovascular pathways. Diminished sGC function contributes to several conditions, including cardiovascular diseases. sGC-induced cGMP increase ultimately affects vascular relaxation, inhibition of platelet aggregation, and altered neurotransmission._x000D_<br>_x000D_<br>sGC GUCY1A2 is upregulated in several cancers and promotes tumorigenesis. GUCY1A2 regulation is particularly dysregulated in cervical, prostate, and gastric cancer. The expression of GUCY1A2 is being proposed as a prognostic indicator for the outcome of gastric cancer and prostate cancer.</p>

<p>Anaplasma Phagocytophilum Surface Protein AipA, Recombinant is a protein for use in pharmaceutical and diagnostic applications. Please enquire for more information about Anaplasma Phagocytophilum Surface Protein AipA, Recombinant including the price, delivery time and more detailed product information at the technical inquiry form on this page.</p>

<p>Ac-CTEANTDRFPTTEEVF-NH2 is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. Ac-CTEANTDRFPTTEEVF-NH2 is provided at greater that &gt;85% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer Ac-CTEANTDRFPTTEEVF-NH2 in bulk quantities in addition to our standard pack sizes.Please enquire for more information about Ac-CTEANTDRFPTTEEVF-NH2 at the technical inquiry form on this page</p>

<p>H-DSTPNTTEK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-DSTPNTTEK-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-DSTPNTTEK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-DSTPNTTEK-OH at the technical inquiry form on this page</p>

<p>H-LAAYLFT-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-LAAYLFT-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-LAAYLFT-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-LAAYLFT-OH at the technical inquiry form on this page</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Peptide Ac-CEKEEDERVQGGDREPLLQEE-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-FIKPILEKMDG-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-FIKPILEKMDG-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-FIKPILEKMDG-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-FIKPILEKMDG-OH at the technical inquiry form on this page</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>