Prodotti biochimici e reagenti

<p>Peptide H-PPYTIVYFPVR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-KITDFGLAK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-KITDFGLAK-OH is provided at greater that &gt;90% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-KITDFGLAK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-KITDFGLAK-OH at the technical inquiry form on this page</p>

<p>Peptide H-GTVVVPTLDSVLYDNQEFPDPEK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Inhibitor of the histone methyltransferase SETD8 that supresses methylation of the K20 residue in histone 4. UNC 0379 treatment of human glioma reduced recruitment of 53BP1 protein to double strand breaks and sensitised cells to radiotherapy without altering cell cycle kinetics.</p>

<p>Peptide H-LDIDSAPITAR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>The CKMB antibody is a specific antibody that targets the CK-MB isoenzyme, which is a form of creatine kinase. This antibody is commonly used in Life Sciences for research purposes and in diagnostic applications. Monoclonal antibodies like the CKMB antibody are highly specific and can bind to their target with high affinity, making them valuable tools in various scientific fields.</p>

<p>Human IgA1 protein is a glycoprotein that plays a crucial role in the immune system. It is a type of immunoglobulin that functions as an antibody, providing protection against pathogens and foreign substances. Human IgA1 protein has multiple characteristics and functions, including stimulating hepatocyte growth, acting as an electrode for cellular signaling, and interacting with androgens, collagens, inhibitors, monoclonal antibodies, and other binding proteins.</p>

<p>Peptide H-QV^DYYGLYY-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-VDNSSLTGESEPQTR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-SLMEQIPHL^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Influenza B antibody was raised in mouse using Influenza B as the immunogen.</p>

<p>H-CTHPHLPRALMRS-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-CTHPHLPRALMRS-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-CTHPHLPRALMRS-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-CTHPHLPRALMRS-OH at the technical inquiry form on this page</p>

<p>Peptide H-AEIEYLEK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>PUMA2A is a modified version of the PUMA peptide, a pro-apoptotic protein that promotes cell death. PUMA normally activates proteins like BAK and BAX, which cause mitochondrial damage and trigger apoptosis. However, PUMA2A has two alanine substitutions that render it inactive. It's often used as a negative control in experiments studying apoptosis, as it should not induce cell death. This is because the BCL-2 family of proteins, which includes PUMA, are crucial regulators of apoptosis, and disrupting their function can impact cell survival.</p>

<p>Piracetam is a nootropic drug that is used for the treatment of sickle cell disease, alcohol dependence and as a cognitive enhancer. This drug is a cyclic derivative of GABA and has neuroprotective and anticonvulsant properties. Piracetam has been said to improve neuronal plasticity.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Peptide Ac-CDDLIKVVEELTRIH-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide derived from the gastrointestinal hormone Motilin, secreted from endocrine cells in the small intestines, mainly from the jejunum and duodenum, in response to the fasting, drinking water or the mechanical stimulus of eating.</p>

<p>Peptide H-LEAFL^TQK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide substrate for the kallikrein-related peptidase 7 (KLK7), the most abundant KLK family protease in the stratum corneum (outermost layer of the epidermis). KLK family have been implicated in several key homeostatic processes and in skin diseases that feature impaired desquamation. Increased levels of KLK7, have been identified in the stratum corneum of patients with atopic dermatitis (AD). T-helper type 2 cytokines, including interleukin 4 (IL-4) and-IL-13, can stimulate expression of KLK7, suggesting a direct link between inflammation in AD and KLK7 levels.KLK7 cleaves its substrates after tyrosine or phenylalanine residues. This peptide contains a C-terminal 7-amino-4-methylcoumarin (AMC) fluorescent tag, which is quenched when linked to the peptide via the amide bond. AMC is cleaved from the peptide by KLK7, upon cleavage the AMC fluorescence is activated.</p>

<p>CD31 antibody was raised in mouse using lewis rat microglia as the immunogen.</p>

<p>ProBNP protein is a versatile product used in the field of Life Sciences. It is a protein that can be targeted with both polyclonal and monoclonal antibodies for various research purposes. The protein is commonly used in studies related to cardiomyocytes, as it plays a crucial role in cardiovascular health. ProBNP protein is also involved in the regulation of annexin, an inhibitory factor that affects cellular processes.</p>

<p>Residues 17-29 of the LL-37 peptide, also known as FK-13. FK-13 has near-similar anti-microbial and anti-cancer properties to LL-37. This core fragment also contains part of the LL-37 actin binding domain and can associate weakly with actin, actin binding protects this fragment from protease degradation.LL-37 is a member of the large cationic family of anti-microbial peptides called cathelicidins which have broad-spectrum anti-microbial activity and are expressed in many species. The only cathelicidin found in humans is LL-37- this is produced in epithelial cells, by proteolytic cleavage from the C-terminal of the hCAP-18 protein. LL-37 can be processed into several different forms of anti-microbial peptides. As well as its anti-microbial properties LL-37 also has anti-cancer properties and regulates many aspects of the innate immune system- overexpression of LL-37 has been linked to autoimmune diseases such as asthma and psoriasis.</p>

<p>Peptide H-EFSEVEGR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-TFRRRL-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-YKRWIILGLNK-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-YKRWIILGLNK-OH is provided at greater that &gt;90% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-YKRWIILGLNK-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-YKRWIILGLNK-OH at the technical inquiry form on this page</p>

<p>The hCG alpha antibody is a highly reactive monoclonal antibody that is used in various applications in the field of Life Sciences. It can be used for ultrasensitive detection of human chorionic gonadotropin (hCG) in human serum, making it a valuable tool for pregnancy testing and fertility studies. The hCG alpha antibody is also commonly used in flow immunoassays and other diagnostic assays to detect the presence of hCG.</p>

<p>Hemoglobin antibody was raised in mouse using purified human hemoglobin as the immunogen.</p>

<p>The Digoxigenin antibody is a powerful tool used in Life Sciences research. It is a monoclonal antibody that specifically binds to digoxigenin, a small molecule commonly used as a labeling reagent in molecular biology experiments. This antibody has been extensively validated for its high specificity and sensitivity in various applications.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Keratin-Derived anti-microbial Peptides (KDAMPs), are peptide fragment of the intermediate filament protein cytokeratin 6A. They were originally isolated from lysates of human corneal epithelial cells. KDAMPs exhibit coil structures with low α-helical content and are smaller and more stable than other known host-expressed anti-microbials.Multiple length KDAMPs have been studied for their anti-microbial properties, and different fragments show different anti-microbial spectrums. The 19 mer KDAMP peptide is rapidly bactericidal against multiple clinical isolates of Pseudomonas aeruginosa, and shows even greater activity against-Streptococcus pyogenes. However it is not active against Staphylococcus aureus-or-Escherichia coli.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Peptide Myr-SIYRRGARRWRKLYRAN-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide Ac-SEEEDPAPSRKIHFSTAPIQVFST-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Peptide H-ALREEEEGV^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>The dodecapeptide AR71 prevents melanoma inhibitory activity (MIA) dimerisation and hence inhibits (MIA). It therefore has the potential to be used as a therapeutic in melanoma.</p>

<p>Cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca2+-binding site and can activate phosphodiesterase in the absence of Ca2+ and inhibit Ca2+ mediated cytotoxicity and apoptosis.</p>

<p>Myelin oligodendrocyte glycoprotein (MOG) is a member of the immunoglobulin (Ig) protein superfamily and is expressed exclusively in the central nervous system on the surface of myelin sheaths and oligodendrocyte processes. MOG is expressed at the onset of myelination, and therefore is a potential marker for oligodendrocyte maturation.MOG contains an extracellular domain, a transmembrane domain, a cytoplasmic loop, a membrane-associated region and a cytoplasmic tail.  MOG may function as a cell surface receptor or cell adhesion molecule.  Fifteen different alternatively spliced isoforms have been detected in humans. These are present either on the cell surface, the endoplasmic reticulum in the endocytic system, or in secreted form.The secreted form of MOG may trigger autoimmunity if released into the cerebrospinal fluid and periphery. MOG is thought to be a key target for autoantibodies and cell-mediated immune responses in inflammatory demyelinating diseases such as multiple sclerosis (MS) and is therefore widely studied in this field.The MOG (35-55) fragment is the most potent auto-antigenic region of MOG, and the most effective at inducing experimental autoimmune/allergic encephalomyelitis (EAE), an animal model that resembles MS. This peptide has a free carboxylic acid at the C-terminus, an amide version is also available in our catalogue.</p>

<p>Peptide H-FL^SLDYIPQR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Wilms tumor protein is a protein that is encoded by the WT1 gene on chromosome 11p in humans. WT1 is a tumour suppressor gene associated with the development of Wilms' Tumour, from which it was named. Mutations in exon 7 and 9 of WT1 have been recurrently identified in acute myeloid leukemia and associated with poorer prognosis and chemotherapy resistance.The WT1 peptide is a transcription factor that contains four zinc finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system.WT1 has been ranked by the National Cancer Institute (NCI) as the Number 1 target for cancer immunotherapy.The arginine is isotopically labelled with carbon-13(6) and nitrogen-15(4).</p>

<p>CA 15-3 protein is a colloidal protein that plays a crucial role in various Life Sciences applications. It is associated with annexin A2 and is commonly used in research as a target for monoclonal antibodies. These neutralizing antibodies can be utilized to study the function of CA 15-3 protein and its interactions with other molecules, such as chemokines. In clinical settings, CA 15-3 protein has been found in pleural fluid and may serve as a potential biomarker for certain diseases, including cardiomyocyte dysfunction. Additionally, it has been observed to have natriuretic effects, suggesting its involvement in regulating fluid balance. Researchers often employ streptavidin-conjugated annexin A2 to detect activated forms of CA 15-3 protein. This allows for the visualization and quantification of this important biomolecule. Overall, CA 15-3 protein is an essential component in the field of Native Proteins &amp; Antigens research, providing</p>

<p>VEGFR2 single chain antibody was raised in E.coli using Highly purified human sVEGFR-2/KDR as the immunogen.</p>

<p>Albumin (237-251) Bovine is derived from the globular protein Albumin and is found in the blood-plasma of humans (known as Human Serum Albumin, HSA) where it serves to maintain plasma pressure and nutritional balance. Another role it carries out is the transportation of bound molecules through the blood. Bovine serum albumin (BSA), composed of 583 amino acids, is very similar to HSA thus allowing BSA to be used as a successful model and a standard protein in laboratory experiments.Although BSA and HAS share homology in their three domains, I, II and III, BSA contains 2 tryptophan whereas HAS only contains 1 tryptophan residue.In agriculture the presence of the albumin protein has been used to assess the health of cows to ensure that a suitable quality of milk and meat are produced. Moreover it is important to detect bovine albumin in food and pharmaceutical products due to it being an allergenic protein.</p>

<p>Custom research peptide; min purity 95%. For different specs please use the Peptide Quote Tool</p>

<p>Peptide H-AVCVLK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>The hCG antibody is a monoclonal antibody that specifically targets and inhibits the activity of human chorionic gonadotropin (hCG). It binds to hCG, preventing it from interacting with its receptors and exerting its biological effects. This antibody has been widely used in research and diagnostic applications in the field of Life Sciences. It has been shown to inhibit the growth of cells that express high levels of c-myc or hepatocyte growth factor, suggesting its potential as a therapeutic agent for certain types of cancer. Additionally, this antibody can be used to detect and quantify hCG levels in various biological samples, making it valuable for pregnancy testing and monitoring. Its high specificity and affinity make it a reliable tool for scientists and clinicians working in the field of reproductive biology.</p>

<p>Peptide Ac-SLSRFSWGA-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>H-ELSGIPPAPRGVPQIEVTFD-OH is a custom peptide that can be synthesized rapidly by our peptide experts in under 2 weeks. H-ELSGIPPAPRGVPQIEVTFD-OH is provided at greater that &gt;95% purity (HPLC) from Cymit Quimica for a variety of research applications. We also offer H-ELSGIPPAPRGVPQIEVTFD-OH in bulk quantities in addition to our standard pack sizes.Please enquire for more information about H-ELSGIPPAPRGVPQIEVTFD-OH at the technical inquiry form on this page</p>

<p>Peptide Fluor-YGGFMRGL-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.</p>

<p>Biotin-PEG2-Claudin-6 is derived from the tight junction protein Claudin-6 which is encoded by the CLDN6 gene and can be found within epithelial cell to cell contacts. The Claudin family are transmembrane proteins containing two extracellular loops and are involved in maintaining cell polarity and controlling paracellular ion flux.The expression of Claudin-6 is most commonly seen in early embryonic development where it plays a role in the regulation of blastocyst formation through tight junction enhancement. It is also an important factor for epidermal differentiation and barrier formation. Although it is more commonly seen in embryonic development it is also expressed in mammary epithelial cells. Studies have also shown Cldn6 to be a tumour suppressor in breast cancer.This peptide has a covalently bonded N-terminal Biotin tag that can be used for detection and purification and contains a polyethylene glycol spacer (PEG2).</p>