Building Blocks

PB-22 is a synthetic cannabinoid, which can be classified as a CB1 receptor agonist. It is one of the many cannabinoids that have been created in an attempt to circumvent drug laws by creating compounds that are similar to those found in cannabis but have different chemical structures. PB-22 has shown to increase locomotor activity and stimulate the cb1 receptor in mice. Magnetic resonance spectroscopy (MRS) and assays were used to determine the binding affinity of PB-22 for the CB1 receptor. The MRS data showed that PB-22 bound with high affinity to the CB1 receptor and had a lower affinity for CB2 receptors. This suggests that PB-22 may be more potent than other synthetic cannabinoids, such as JWH-018 and CP 55,940, which bind better with CB2 receptors than CB1 receptors.
PB-22 is an analog of JWH-073 and has been shown to have a stronger effect on locomotor activity than JWH

Versatile small molecule scaffold

Versatile small molecule scaffold

4-Amino-N-(4-methoxyphenyl)benzamide is a catalytic sulfamate that has been optimized for use in the synthesis of benzimidazole derivatives. 4-Amino-N-(4-methoxyphenyl)benzamide is used as a reagent for the preparation of aldehydes from sulfamic acid and various types of carboxylic acids. The reaction mechanism involves nucleophilic attack by the hydroxyl group from the sulfamate on the carbonyl carbon atom to form an intermediate, which then reacts with water to release hydrogen sulfate and form a new double bond.

(S)-(+)-1-Bromo-2-methylbutane is a chiral molecule with two stereoisomers, the cis and trans forms. The cis form has been observed to be the more stable of the two. It is a functional theory that these two forms are not mirror images of each other because they have different conformations. (S)-(+)-1-Bromo-2-methylbutane has been used in the synthesis of a number of important molecules. The stereoisomers can be distinguished by conformational analysis and optical microscopy. (S)-(+)-1-Bromo-2-methylbutane also has an application in biotechnology for use as a precursor for hydrazones, which are important in organic chemistry and molecular biology, such as DNA sequencing.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-[(3-Nitrophenyl)formamido]acetic acid (2NPA) is a modifying agent that has been used in the modification of carboxyl groups. It can react with nucleophiles to form adducts and with carbodiimides to form ureas. 2NPA reacts with amino acids, peptides, and other nitrogenous compounds at their carboxyl groups to form ester or amide bonds. The nature of the residues after modification varies depending on the nature of the carboxyl group that was modified.

Acetic acid, dibromo-, ethyl ester is a reactive molecule that can be used as a nucleophilic substituent. It has hydroxyl group and ruthenium complex. It is a particle that can be used in the production of monoclonal antibodies. Acetic acid, dibromo-, ethyl ester also has viscosity and polycarboxylic acid. This chemical reacts with β-unsaturated ketones to form polymerization initiator. Acetic acid, dibromo-, ethyl ester also has carbonyl group and monoclonal antibodies. Acetic acid, dibromo-, ethyl ester can be conjugated with ethyl bromoacetate to produce conjugates.

5-Fluoro-2-nitrobenzoyl chloride is a conformationally locked macrocyclic compound that has been synthesized by solid phase synthesis. It is found in two conformational states and can be made to switch between these two states by applying a force to the molecule. This conformation can be controlled by changing the side chain of 5-fluoro-2-nitrobenzoyl chloride, which can be done experimentally. The conformational behavior of this macrocycle was studied using molecular dynamics simulations and it was found that there are four possible conformations for the molecule. The conformations with different side chains were found to have different energies, which could be used as a measure of their relative stability.

Versatile small molecule scaffold

Ethyl 2-(indol-3-yl)-2-oxoacetate is a hydroxy derivative of the amino acid tyrosine. It inhibits the enzyme tyrosine hydroxylase, which catalyzes the conversion of tyrosine to L-DOPA. This in turn affects dopamine synthesis and has an inhibitory effect on rat brain. Ethyl 2-(indol-3-yl)-2-oxoacetate also inhibits methylmagnesium borohydride in vitro, which is a reagent that breaks down esters, amides, and nitriles. Tyrosine hydroxylase is inhibited by the presence of two hydroxy groups on the ethyl side chain and one hydroxy group on the indole ring. It can be used as a structural analogue for other drugs that are used to treat Parkinson's disease or depression.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

3-Acetylpyrrolidine-2,4-dione is an experimental drug that belongs to the class of metal hydroxides. It has been shown to have anti-tumor activity in vitro and in vivo against a variety of malignant tumors. 3-Acetylpyrrolidine-2,4-dione also inhibits the growth of pigweed and other plants by inhibiting the production of tenuazonic acid. This compound is a tautomeric form of tenuazonic acid, which is also known as 2,4-pentanedione. The carboxylate group on this molecule may be responsible for its herbicidal activity.

5-Ethenyl-2-methoxyphenol is a volatile compound that has been isolated from the bark of the cinnamon tree. It has shown anticancer activities "in vitro" and "in vivo". 5-Ethenyl-2-methoxyphenol has been shown to be demethylated by cytochrome P450 enzymes, which may result in its antitumor activity. This active compound can also be detected in postharvested fruit and vegetables as well as processed foods such as apple juice, tomato sauce, and dried fruits. 5-Ethenyl-2-methoxyphenol is responsible for the characteristic flavor of cinnamon, so it is often used as a flavoring agent in food processing.

Versatile small molecule scaffold

2-Cyclohexylpropane-1,3-diol is a substrate for porcine pancreatic lipase. It is hydrolyzed by this enzyme, which is stereoselective and enantioselective. 2-Cyclohexylpropane-1,3-diol also has properties that are similar to angiotensin, a peptide that is secreted by the human body. This substance can be used as a solvent for other organic compounds in chemical reactions.

5-Phenyl-1H-pyrazin-2-one is a potent inhibitor of tyrosine kinase, which is an enzyme that regulates the activity of cells by transferring phosphate groups from ATP to tyrosine residues. This drug binds to the ATP binding site, resulting in inhibition of the enzyme's activity and reduced cell proliferation. 5-Phenyl-1H-pyrazin-2-one has been shown to be effective in treating rheumatoid arthritis and other autoimmune diseases, with no adverse effects on bone metabolism or blood pressure. It also has no effect on platelet aggregation or erythrocytes.

1-Monotetranoin is a fatty ester that is involved in the process of lipolysis, which is the breakdown of fat cells. Lipolysis occurs when an enzyme called lipase hydrolyzes triglycerides into glycerol and three fatty acids. 1-Monotetranoin has been shown to be a potent stimulator of growth factor production and cell proliferation in vivo models. It has also been shown to be effective at inhibiting angiogenic processes in vitro, including the release of growth factors from fat cells. The neutral pH optimum for 1-monotetranoin is between 7 and 8, which may be due to its hydrophobic nature.

1-Bromo-2-(methoxymethyl)benzene is a boronic acid that is used in the synthesis of palladium complexes. It is synthesized by reacting 1-bromobenzene with methanol and methoxymethyl chloride. The 1-bromo-2-(methoxymethyl)benzene has been used as a ligand for palladium complexes, which are often used to catalyze organic reactions, such as the metathesis reaction. Synthetic methods have been developed to produce the compound and NMR spectra have been obtained to provide kinetic data on these reactions.

Versatile small molecule scaffold

2-Allylcyclohexanone is an unsaturated ketone that is synthesized by the ring-opening of allyl cyclohexane carboxylate with sodium hydroxide. It can be used as a chemical intermediate for the synthesis of other compounds. 2-Allylcyclohexanone can also be used to react with hydroxide solution to produce a salt and an alcohol. The hydroxide solution can act as a base, reducing the carbonyl group in the presence of an acid to form the corresponding alcohol. This reaction is stereoselective because it only occurs when there are two different groups on adjacent carbons.
2-Allylcyclohexanone has been shown to inhibit non-nucleoside reverse transcriptase inhibitors (NNRTIs) such as nevirapine, efavirenz, and delavirdine. In addition, it has been found to have functional groups that are capable of reacting

Versatile small molecule scaffold

1-Chloro-4-isocyanobenzene (1CI) is an organic compound that has been used as a chemical probe for the detection of amines and other molecules on metal surfaces. The frequency shift in Raman spectra, which is observed after the addition of 1CI to the metal surface, is used to detect amines. 1CI has also been shown to be a potent inhibitor of mitochondrial function. This molecule binds to nucleophilic sites on metal surfaces and forms covalent bonds with them, leading to a high degree of inhibition.
1CI can be synthesized in three steps from commercially available starting materials and is relatively easy to purify.

Benzo[d][1,2,3]thiadiazole is a benzothiadiazole with a redox potential of -0.25 V that is stable in the absence of oxygen and light. It can be used to synthesize chemical pesticides by reacting with hydrochloric acid. The reaction mechanism of benzo[d][1,2,3]thiadiazole has been determined using nuclear magnetic resonance spectroscopy and quantum chemical calculations. This compound reacts with hydrogen bond acceptors on the enzyme active site to form covalent bonds. It also interacts with the enzyme's steric environment by forming hydrogen bonds and van der Waals forces. Benzo[d][1,2,3]thiadiazole also emits light when it reacts with nitric oxide in solution.

Versatile small molecule scaffold

1,3-Diazaspiro[4.4]nonane-2,4-dione (1) is a new fungicide that was shown to have fungicidal activity in vitro against the grapevine pathogens Plasmopara viticola and Plasmopara obducens. This compound has been isolated from the plant Express erythroxylum coca (Erythroxylum coca). The compound belongs to the class of diaza spiro compounds and is a member of a family of diaza spiro compounds with antifungal activity. One possible mode of action for 1 is that it inhibits the synthesis of DNA by binding to bacterial DNA gyrase.

1-Bromo-1-methylcyclohexane is a monomolecular gas that is used as an intermediate in organic synthesis. It reacts with halides to form cyclopentyl derivatives. This reaction has been shown to be faster than the corresponding reaction of 1-bromocyclohexane with chlorides or bromides. The rate of this reaction may be due to the polarizability and conformational changes of the molecule upon substitution by a methyl group. 1-Bromo-1-methylcyclohexane is also an ionizing reagent, which means it can cause electrophilic reactions to occur on other molecules. It has been found that the solvent effect on this product can affect its reactivity, with solvents such as water having more of an effect than solvents such as benzene. 1-Bromo-1-methylcyclohexane has been shown to interact with other compounds in both transfer and complex

6-Chloro-9-(propan-2-yl)-9H-purine is an intermediate in the synthesis of nucleoside analogues. It is obtained by the catalyzed reaction of acetonitrile and purines, which undergoes regioisomerization to form a mixture of 6-chloro-9-(propyl)- and 6-chloro-9-(butyl)purine. This intermediate can be used for the alkynylation of amino acids or peptides with alkynes. The selective formation of one regioisomer can be achieved by using a chiral catalyst or by reacting with an optically active reagent such as (+)-camphor sulfonic acid.

Versatile small molecule scaffold

2-Bromobenzaldoxime is a biologically active molecule that has been shown to have significant physiological activities. It is an aldehyde, which is metabolized by the liver or kidneys into the corresponding alcohol, 2-bromoethanol. 2-Bromobenzaldoxime has been shown to be synthesized from diethyl ether and potassium phosphate in the presence of amino acids. The reaction proceeds with dehydration of the intermediate bromohydrin to form an aldoxime. This molecule can be used as a pharmaceutical drug for various diseases such as diabetes mellitus, hypertension, and inflammation.

Amyl acetate is a reactive, volatile organic compound that is used in the manufacture of plasticizers, resins, and synthetic rubber. It is also used as a solvent for dyes and pigments, as well as a flavoring agent in food processing. Amyl acetate has been shown to have antimicrobial properties against human pathogens such as methicillin-resistant Staphylococcus aureus (MRSA), Escherichia coli, and Salmonella enterica. The antimicrobial activity of this molecule may be due to its ability to react with cellular components such as proteins and lipids. Amyl acetate also inhibits the growth of microorganisms by inhibiting their synthesis of essential biomolecules like amino acids and nucleic acids.

4-Hydroxy-2-naphthoic acid is a hydrocarbon with a carboxylic acid group. It can act as an antagonist to the hydrocarbon receptor (HCR). 4-Hydroxy-2-naphthoic acid has been shown to be effective in treating colon cancer cells in vitro, and has been shown to inhibit the growth of cancer cells in vivo. This compound is also effective at inhibiting the proliferation of human colon cancer cells (Caco2) that have been exposed to benzo(a)pyrene, an aromatic hydrocarbon found in cigarette smoke. The mechanism by which this drug inhibits cell proliferation is not fully understood but may involve inhibition of cytochrome P450 1A1 (CYP1A1), which metabolizes benzo(a)pyrene into carcinogenic intermediates. 4-Hydroxy-2-naphthoic acid has also been shown to be anisotropic and microreactor, meaning

Dec-9-ynoic acid is a synthetic fatty acid that is a precursor to several biologically important substances. It is labile and easily oxidized by air, light, or heat. Dec-9-ynoic acid has been shown to be a central metabolic intermediate for the biosynthesis of polyunsaturated fatty acids. It can also be converted into linolenic acid, which is an essential fatty acid that cannot be synthesized by humans. Dec-9-ynoic acid exists in two geometric isomers: cis and trans. The cis form exhibits kinetic properties that are different from the trans form. Dec-9-ynoic acid has been studied as a potential treatment for human diseases such as diabetes mellitus type 2, Parkinson's disease, Alzheimer's disease, schizophrenia, and depression.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

3,5-Dichlorophthalic acid is a divalent organic acid that is used as an intermediate in the production of other chemicals. 3,5-Dichlorophthalic acid is used as a regulator of plant growth and development. It can also be used to make different n-substituted compounds, such as naphthalene, phthalic anhydride, and 2,6-dichloro-pyridine.

2-Methylbenzene-1,3-dicarbaldehyde is a divalent hydrocarbon that has an oxidation catalyst. This compound is used as an intermediate in the production of drugs and pharmaceuticals. It has been shown to have cardiovascular disorders, such as vasodilatation and hypotension. The mechanism of action is not fully understood but may be related to its ability to act as a nitrovasodilator by increasing nitric oxide (NO) release. 2-Methylbenzene-1,3-dicarbaldehyde also produces psychotic disorders when long term exposure occurs. This compound has been shown to have neurotoxic effects in animal models with long term exposure.

Versatile small molecule scaffold

2-(4-Fluorophenyl)acetamide (FFAA) is a broad-spectrum antiviral drug that has been evaluated against picornavirus, enterovirus, and rhinovirus. FFAA has been shown to be effective in the treatment of acute enterovirus infections in mice. This compound was also found to have a cytopathic effect on cells infected with enteroviruses in culture. It binds to the virus's RNA-dependent RNA polymerase and prevents viral replication. FFAA is not active against influenza A or B viruses, but it is active against influenza C virus. This compound has also been found to have medicinal properties, as it can inhibit the growth of human lung cancer cells in culture and may be useful for treating cancers such as leukemia.

(3,3,3-Trifluoroprop-1-yn-1-yl)benzene is a reaction product that can be used to inhibit the activity of metalloprotease and as an anti-cancer agent. This compound inhibits the enzyme that causes chronic kidney disease and degenerative diseases. It is a potent inhibitor of metalloprotease, which is involved in cancer progression, fatty acid synthesis and bone formation. The effective dose for this drug is between 1 and 10mg/kg body weight. It has been shown to have an asymmetric synthesis with the use of amido groups. (3,3,3-Trifluoroprop-1-yn-1-yl)benzene also has antirheumatic properties due to its ability to inhibit proteases such as matrix metalloproteinases and cathepsins.

Versatile small molecule scaffold

3-Chlorophenylurea is a quinazolinone that inhibits the growth of candida glabrata. This compound has been shown to inhibit efflux pumps, which are proteins that pump out drugs from the cell. 3-Chlorophenylurea has been shown to inhibit the efflux of fluconazole, a drug used to treat fungal infections, and thiourea, a compound that is known for its cytotoxicity. The inhibition of these two compounds suggests that 3-chlorophenylurea could be an efflux pump inhibitor.

Versatile small molecule scaffold

2,2-Dibromopropane is a synthetic chemical that has been used as a precursor in the production of nylon. It is an activator that can be used to form covalent bonds with reactive groups on other molecules. The activation energy for the reaction with piperazine is between 104 and 106 kJ/mol. 2,2-Dibromopropane undergoes acylation reactions under certain conditions, forming reaction products such as 2,2-dibromoethyl acetate and 2,2-dibromoethanol. The molecular weight of 2,2-dibromopropane is 192.19 g/mol and its structural formula is CHBrCHBrCHBrCHBrC≡C≡C≡C≡C≡C≡CC(O)OH.

2-[3-(Propan-2-yl)phenoxy]acetic acid is a chemical compound that is used as an additive in benzene, and is a phytotoxic chemical. It prevents the formation of chlorophyll by blocking electron transport and inhibiting photosynthesis. 2-[3-(Propan-2-yl)phenoxy]acetic acid is used to induce callus tissue from lettuce, radish, and other plants. This compound also inhibits the growth of various bacteria including Escherichia coli and Pseudomonas aeruginosa.

3-Phenylbut-2-enoic acid is a prochiral, carbonyl compound that can be used in the synthesis of chiral pharmaceuticals. Mechanistic studies have shown that 3-phenylbut-2-enoic acid is a catalytic hydrogenation reagent that converts prochiral substrates to their corresponding chiral products. When combined with binap and butenoic acid, 3-phenylbut-2-enoic acid can catalyze the asymmetric synthesis of butenoate. The reaction yields high enantiomeric excesses and good yields.

Versatile small molecule scaffold

3-Fluorobenzene-1-sulfonyl fluoride is a chemical compound that can be used as a catalyst to synthesize organic compounds. It is a colorless liquid, which is soluble in water and organic solvents. This catalyst has been shown to be more efficient than the traditional catalysts, such as tetraphenylphosphonium chloride, potassium fluoride or sodium borohydride. 3-Fluorobenzene-1-sulfonyl fluoride also reacts with nitro groups to produce dinitro compounds, which are valuable synthetic intermediates for the production of dyes and pharmaceuticals. The synthesis of this compound can be carried out in high yields with stoichiometric amounts of reactants.

Methyl 2-octynoate is a chemical that has been shown to bind to the nicotinic acetylcholine receptor. Methyl 2-octynoate has been shown to have antitumor activity in various types of cancer cells, including breast, prostate, and lung cancer cells. This chemical is not known to be chemically stable or film-forming. It also disrupts mitochondrial membrane potential and reduces the endpoints of oxidative phosphorylation. Methyl 2-octynoate was found to have low potency against cancer cells in vitro and in vivo.

Versatile small molecule scaffold

Versatile small molecule scaffold

1-Benzothiophene-5-carbonitrile is a heterocyclic compound that is formed by condensation of ethyl azidoacetate with indole under catalysis. It can be used in the synthesis of heterocycles. The yield of 1-benzothiophene-5-carbonitrile is about 56%.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Please enquire for more information about 4,5-Dihydro-1H-imidazol-2-amine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

3-Hydroxy-5-methylpyridine (3HMP) is a chemical substance that has been classified as an amine. It is a product of the metabolism of purines, which are nitrogenous bases found in DNA and RNA. 3HMP is produced by aerogenic bacteria (such as Enterobacter), and can be used to estimate the number of these bacteria present in water samples. 3HMP has been shown to have antiviral properties against influenza virus, and can be used as a biomarker for the presence of other viruses in animals. 3HMP also has mineralization properties, which have been studied extensively, particularly with regards to pancreatic disease.

2-Bromo-3,3,3-trifluoro-1-propene is a chemical compound that has been synthesized in an asymmetric reaction. The reactant is bromopropane and the product is 2,2,2-trifluoropropene. The methylene group on the propene molecule is activated by the nucleophilic attack of a fluoride ion from hydrogen fluoride to form a cavity with a highly strained bond. The kinetic study of this reaction revealed that the activation energy for the reaction is 42 kJ/mol. Palladium-catalyzed coupling reactions are catalyzed by palladium and require nonpolar solvents such as toluene or dichloromethane. This type of reaction has been shown to be exothermic with an isolated yield of 1%.

Versatile small molecule scaffold

1-Hydroxycyclopentane-1-carbonitrile is a monomer that is hydrolyzed to form benzoin and cyanohydrins. It can be used in the production of scifinder as a monomer or dimerizer.

4,5-Dihydroxy-2,3-pentanedione is a carbonyl compound that is the product of the oxidation of ascorbic acid. It is used in wastewater treatment and has antimicrobial properties against infectious diseases. This compound has been shown to inhibit protein synthesis by binding to the ribosome and preventing the formation of peptide bonds between amino acids. 4,5-Dihydroxy-2,3-pentanedione has also been shown to bind to plasma proteins, which may be due to its acyl chain structure. 4,5-Dihydroxy-2,3-pentanedione can be synthesized in a catalytic mechanism that involves dehydroascorbic acid and molecular oxygen.

Piperyline is an alkanoic acid that has shown to be effective against skin cancer. It also has antimicrobial properties, which may be due to its ability to bind metal ions and form polymeric compounds. Piperyline inhibits microbial growth by inhibiting the synthesis of proteins and nucleic acids. The antimicrobial activity is related to its cationic polymerization with hydroxyl groups, which forms a structure that can inhibit microbial enzymes and disrupt microbial cell membranes. This compound also interacts with the skin's natural lipids, making it difficult for microorganisms to attach and grow on the skin. Piperyline is synthesized in organic chemistry laboratories as an amide precursor of other pharmaceuticals such as penicillin.