Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

3-bromo-1-methyl-1H-indole is a chemical compound with the molecular formula C8H7BrN. It can be prepared by reacting 1,3-dimethylindole with bromine in the presence of potassium carbonate and palladium chloride. 3-Bromo-1-methyl-1H-indole has been used to synthesize tetramers of 1,3,5,7,9,11,13,15-(2)naphthacenecarboxylic acid. This compound has also been used as a lithiation reagent for substituted anilines and benzamides. The substituents on the indole ring allow for cyclic reactivity and functional groups that are reactive towards hydrolysis or lithiation. 3bromo 1methyl 1H indole is an example of a heterocyclic compound because it contains two rings. The first ring consists of five carbons

Versatile small molecule scaffold

Versatile small molecule scaffold

[(Pent-4-en-1-yloxy)methyl]benzene is an ester that is used in the synthesis of other compounds. It is produced by the catalytic cleavage of sulfoxides and interacts with a variety of ligands. [(Pent-4-en-1-yloxy)methyl]benzene can be used as a precursor to allylic esters, which are important in organic synthesis because they are often more reactive than their parent olefin. It has been shown to undergo allylic oxidation and allylic esters, which are important reactions in organic chemistry. Allylic oxidation involves the addition of oxygen to an unsaturated carbon atom, while allylic esters involve the addition of an alcohol to an unsaturated carbon atom. This functionalization process is useful for making molecules that contain two different types of functional groups.

Methyl 4-amino-5-methylthiophene-3-carboxylate (AMTC) is a synthetic inhibitor of the enzyme acetyl-coa carboxylase. AMTC is used as a research tool to study the role of acetyl-coa carboxylase in plants and animals. In Arabidopsis, AMTC inhibits the synthesis of fatty acids, leading to reduced seed oil content. It also inhibits transcarboxylase in wheat, which causes an accumulation of acetate. AMTC is synthesized by reacting methyl 4-nitrobenzoate with thieno[2,3,-c]pyrazole in the presence of palladium(II) chloride and potassium carbonate. The product undergoes hydrogenation to give AMTC.

Versatile small molecule scaffold

Versatile small molecule scaffold

Cycloheptyl isothiocyanate is a 1-4c alkyl, azaheterocycle, isothiocyanate that has been shown to be stereoselective. It binds to the sulfur atom of thiols and sulfonylureas, preventing the formation of the reactive intermediate that leads to their hydrolysis. This property can be used for the synthesis of ensembles and aralkyls. Cycloheptyl isothiocyanate also binds to alkenyl groups, which may be useful in synthesizing cycloalkyls or haloalkyls.

3-Amino-4-iodo-1H-pyrazole is a heterocyclic organic compound consisting of an imidazole ring with a pyrazole ring fused at the 2 and 5 positions. It is an analog of pyridazine. The crystal structure of 3-amino-4-iodo-1H-pyrazole has been determined to be orthorhombic, with space group Pnam2. The compound has a number of reactions, including nucleophilic addition, hydroxylation, and nitration. This heterocyclic compound is reactive and can serve as a monofunctional reagent in multiple reactions. 3-Amino-4-iodo-1H-pyrazole is used in the synthesis of other related compounds like 6-(3′,5′ -diamino)imidazo[2,1]benzothiazoles.

Versatile small molecule scaffold

2-[(2-Bromophenyl)formamido]acetic acid is a bile salt that is used to treat liver disease. It is a prodrug of taurocholic acid, which is a naturally occurring bile salt that is essential for the digestion of dietary fats. 2-[(2-Bromophenyl)formamido]acetic acid has been shown to have a constant rate of hydrolysis and can be used as an alternative to taurocholic acid in cases where the latter cannot be metabolized due to genetic defects or enzyme deficiencies. This drug also has the ability to neutralize staphylococcus by converting it into hippuric acid, which can then be excreted from the body via urine. 2-[(2-Bromophenyl)formamido]acetic acid does not undergo any reactions with other drugs, making it ideal for patients who are taking other medications for unrelated conditions.

Versatile small molecule scaffold

Versatile small molecule scaffold

5-Bromo-N-methylthiophene-2-sulfonamide is a potent inhibitor of inflammation. It can be used to treat inflammatory diseases such as arthritis and asthma. 5-Bromo-N-methylthiophene-2-sulfonamide inhibits the production of TNFα, which is an important mediator of inflammation. It also inhibits the production of prostaglandin E2 (PGE2) from arachidonic acid by inhibiting cyclooxygenase enzymes. This drug exhibits potent inhibitory activity against cancer in animals and has been shown to inhibit the growth of ovarian follicles by interacting with fatty acids.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold