Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Benzylaminopyridine is an amide derivative of pyridine. It is a white crystalline solid that melts at about 130°C. 4-Benzylaminopyridine can be prepared by reacting pyridine with benzylamine in the presence of acid, or by heating 4-benzylpiperidine with formamide and sodium hydroxide solution.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 4-(cyanomethoxy)benzoate is a ligand that has been shown to bind to the active site of enzymes such as x-ray, transition, and azide. It has been used in analyses of x-ray diffraction, fluorescent analysis, and hydrothermal synthesis. The tetrazole ring is a key component in the cycloaddition reaction and can be used for the synthesis of coordination polymers. Methyl 4-(cyanomethoxy)benzoate has also been shown to have emission properties.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2,3-Dihydro-1λ⁶-thiophene-1,1,3-trione is a chemical compound that has been synthesized by the reaction of two molecules of dimethyldioxirane with one molecule of thiol. It is a colorless liquid that can be oxidized to 2,3-dihydro-2λ⁶-thiophene-2,2,4(1H)-trione or reduced to 2-(2'-formylphenyl)ethanol. This chemical is an important precursor for the synthesis of sulfur and nitrogen nucleophiles. The yields are high and it is commercially available.</p>

<p>Versatile small molecule scaffold</p>

<p>7-Bromo-5-nitroindoline is a synthetic compound that has been shown to bind to auxin, which is a plant hormone. It has been used in photoaffinity labeling and can be used in the synthesis of other compounds. 7-Bromo-5-nitroindoline binds reversibly and covalently to auxin in the presence of light. The regiospecificity of this binding allows for the determination of specific properties of auxin binding. 7-Bromo-5-nitroindoline is also used as a tritiated label in syntheses and as a deuterated label for photoaffinity labeling.</p>

<p>Versatile small molecule scaffold</p>

<p>(2S)-2-Amino-N,3-dimethylbutanamide is a trifunctional molecule with a carbocycle that belongs to the class of chemical substances. It has been shown to be an inhibitor of human serum enzymes and it can also inhibit the production of human immunodeficiency virus (HIV). It binds to the receptor molecule and prevents HIV from binding to CD4 cells. The toxicological studies for this compound have been performed in cell culture and in animals. There are no reports on its effects on humans. This compound is not metabolized in vivo, but it is rapidly hydrolyzed by esterases in vitro, forming ethyl esters.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Bromo-6-hydroxypyrimidine-4-carboxylic acid is a homologous organic acid that is used as a pharmaceutical preservative. It is most commonly found in acidic pharmaceutical formulations. 5-Bromo-6-hydroxypyrimidine-4-carboxylic acid inhibits the growth of bacteria and fungi by acting as an enzyme inhibitor. The inhibition of enzymes such as lactamase, which breaks down the lactam ring in penicillin, prevents bacterial and fungal growth by preventing them from breaking down their natural cell walls. 5-Bromo-6-hydroxypyrimidine-4-carboxylic acid has also been shown to have potent anticancer activity in the lab setting, although the clinical significance of this has not yet been determined.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Benzeneacetic acid, 3,5-difluoro-hydroxy-, (S)- is a ligand that can bind to transition metals such as copper or iron. It has been shown to be a good sensing ligand for the detection of mandelate and enantioselective for the synthesis of chiral molecules. The divalent bonding between the benzeneacetic acid and the metal may be due to coordination or dipyridyl. The stability of this molecule is also dependent on the type of metal it is bonded with.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl-d3 1-Methyl-d3-1H-indazole-3-carboxylate (MDI) is a reagent used in the synthesis of organic compounds. It is formed by the reaction of lithium aluminum hydride and methyl acetate, which produces a lithiated carboxylic acid. This compound can be reacted with amines to form amides or with thionyl chloride to form sulfonyl chlorides. The reactions are reversible, so it can be regenerated when needed.</p>

<p>Versatile small molecule scaffold</p>

<p>4-Amino-N-(4,5,6,7-tetrahydro-3H-azepin-2-yl)-benzenesulfonamide is a competitive inhibitor of the antibody binding site on the human IgE receptor. It is used as a research tool and as a cell biology reagent to study the function of some ion channels and receptors. 4-Amino-N-(4,5,6,7-tetrahydro-3H-azepin-2-yl)-benzenesulfonamide binds to an allosteric site on the human IgE receptor. This ligand has been shown to activate the receptor in some systems.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-(Furan-2-carbonyl)pyrrolidine-2-carboxylic acid is a peptidomimetic that inhibits the enzyme tyrosinase, which is involved in the synthesis of melanin. This drug has been shown to inhibit the growth of L1210 cells and to be cytotoxic against mouse melanoma cells. 1-(Furan-2-carbonyl)pyrrolidine-2-carboxylic acid binds to the active site of tyrosinase by mimicking its natural substrate, L-DOPA (dopamine). The drug also inhibits certain types of collagen and has allosteric binding properties.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>