Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

4H,5H-Pyrazolo[1,5-a]quinazolin-5-one is a class of heterocyclic compounds that inhibit the parp-1 and parp proteins. These inhibitors are low nanomolar to nanomolar in potency and have been synthesized from chloride and amides. They have been shown to be potent inhibitors of the growth of cancer cells.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1,1-Dimethylguanidine hydrochloride is an oxadiazole derivative that is used in the treatment of bacterial infections. It is a competitive inhibitor of bacterial leukocyte-mediated killing of bacteria and inhibits the growth of staphylococcal and staphylococcus aureus isolates. In vitro, 1,1-dimethylguanidine hydrochloride has been shown to inhibit the growth of gram-positive bacteria by binding to their cell wall. This drug also has a kinetic effect on leukocytes, which may be due to its ability to inhibit the release of reactive oxygen species from these cells.

2-Methyl-5-phenylpentanoic acid is a chiral, asymmetric catalyst for the hydrogenation of prochiral alkenes. It is prepared by the reaction of ferrocenyl phosphine with 2-methyl-5-phenylpentanoic acid. The product is obtained as a racemic mixture of enantiomers that can be separated by chromatography or crystallization.

Versatile small molecule scaffold

Versatile small molecule scaffold

Rac-2,2'-Methylenebis(4-oxatricyclo[5.2.1.0,2,6]dec-8-ene)-3,5-dione is a polyvalent anhydride that has been used as a crosslinking agent in epoxy resin systems and as a viscosity modifier in polymerizable systems. It is also used as an additive to improve the properties of powder coatings and to produce polycarboxylic acid dispersions for use in alkyd resins and oil field chemical additives. The material is supplied as a colloidal suspension in water with a particle size of less than 1 micron. Racemic 2,2'-Methylenebis(4-oxatricyclo[5.2.1.0,2,6]dec-8-ene)-3,5-dione (rac-(1R,2S,6R,7S)-

Versatile small molecule scaffold

1-Hydroxycyclopentane-1-carbonitrile is a monomer that is hydrolyzed to form benzoin and cyanohydrins. It can be used in the production of scifinder as a monomer or dimerizer.

3-Hydroxy-5-methylpyridine (3HMP) is a chemical substance that has been classified as an amine. It is a product of the metabolism of purines, which are nitrogenous bases found in DNA and RNA. 3HMP is produced by aerogenic bacteria (such as Enterobacter), and can be used to estimate the number of these bacteria present in water samples. 3HMP has been shown to have antiviral properties against influenza virus, and can be used as a biomarker for the presence of other viruses in animals. 3HMP also has mineralization properties, which have been studied extensively, particularly with regards to pancreatic disease.

Versatile small molecule scaffold

Please enquire for more information about 4,5-Dihydro-1H-imidazol-2-amine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-Bromo-3,3,3-trifluoro-1-propene is a chemical compound that has been synthesized in an asymmetric reaction. The reactant is bromopropane and the product is 2,2,2-trifluoropropene. The methylene group on the propene molecule is activated by the nucleophilic attack of a fluoride ion from hydrogen fluoride to form a cavity with a highly strained bond. The kinetic study of this reaction revealed that the activation energy for the reaction is 42 kJ/mol. Palladium-catalyzed coupling reactions are catalyzed by palladium and require nonpolar solvents such as toluene or dichloromethane. This type of reaction has been shown to be exothermic with an isolated yield of 1%.

4,5-Dihydroxy-2,3-pentanedione is a carbonyl compound that is the product of the oxidation of ascorbic acid. It is used in wastewater treatment and has antimicrobial properties against infectious diseases. This compound has been shown to inhibit protein synthesis by binding to the ribosome and preventing the formation of peptide bonds between amino acids. 4,5-Dihydroxy-2,3-pentanedione has also been shown to bind to plasma proteins, which may be due to its acyl chain structure. 4,5-Dihydroxy-2,3-pentanedione can be synthesized in a catalytic mechanism that involves dehydroascorbic acid and molecular oxygen.

Piperyline is an alkanoic acid that has shown to be effective against skin cancer. It also has antimicrobial properties, which may be due to its ability to bind metal ions and form polymeric compounds. Piperyline inhibits microbial growth by inhibiting the synthesis of proteins and nucleic acids. The antimicrobial activity is related to its cationic polymerization with hydroxyl groups, which forms a structure that can inhibit microbial enzymes and disrupt microbial cell membranes. This compound also interacts with the skin's natural lipids, making it difficult for microorganisms to attach and grow on the skin. Piperyline is synthesized in organic chemistry laboratories as an amide precursor of other pharmaceuticals such as penicillin.