Building Blocks

Versatile small molecule scaffold

3-(Carboxymethyl)-1H-indole-2-carboxylic acid is an intramolecular cyclization reaction that involves the amination of a propanoic acid and a ring system. This reaction is analogous to the synthesis of 2,5-diaminopentane, which is also a cyclization of an amine to form a five-membered ring. The nmda receptor complex has been shown to be efficient in binding 3-(carboxymethyl)-1H-indole-2-carboxylic acid and other analogues of this compound. In addition, 3-(carboxymethyl)-1H-indole-2-carboxylic acid has shown affinity for the glycine site on the nmda receptor complex. The chemistry behind this drug is not well understood due to its complexity.

Versatile small molecule scaffold

2-(2-Methoxyethyl)aniline is a chemical compound with the chemical formula CH3OCH2NHCH2CH2SCl. It is a colorless, water-soluble liquid and has a pungent odor. 2-(2-Methoxyethyl)aniline reacts with trimethylamine to form trimethylammonium chloride. It also reacts with dimethyl sulfate to form dimethyl sulfate and methylamine. The reaction with hydrazine yields anilinohydrazide and methylated aniline, which can then be converted into borohydride or chlorotrimethylsilane by reacting it with lithium borohydride or chlorotrimethylsilane respectively.
2-(2-Methoxyethyl)aniline is used in the synthesis of various organic compounds such as pharmaceuticals, dyes, pesticides, and perfumes.

Versatile small molecule scaffold

3-[(3-Chlorophenyl)sulfamoyl]benzoic acid is a high purity chemical that has been used as a research tool in the fields of cell biology and pharmacology. 3-[(3-Chlorophenyl)sulfamoyl]benzoic acid has been shown to activate receptors, ligands, and ion channels. It has also been used as an inhibitor of protein interactions. This compound is soluble in DMSO and ethanol, but not water.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Fluconazole is an oral antifungal drug that is used to treat a variety of fungal infections such as candida, cryptococcus, and histoplasmosis. It binds to the 14-alpha-demethylase enzyme in the fungal cell membrane and inhibits the synthesis of ergosterol, which is an essential component of the cell membrane. This prevents the formation of ergosterol crystals that are necessary for maintaining cell shape and function. Fluconazole has been shown to be effective against influenza virus and other viruses that use subunits similar to those found in fluconazole. Fluconazole also has antibacterial properties against bacteria such as Staphylococcus aureus and Streptococcus pneumonia. The pharmacokinetic properties of fluconazole have been studied using ethyl bromoacetate and carboxylate derivatives. Fluconazole has also been shown to inhibit methicillin-resistant Staphylococcus

Versatile small molecule scaffold

1-({[(3-Bromophenyl)methyl]carbamoyl}amino)cyclopentane-1-carboxylic acid is a research tool that can be used in the study of cell biology and pharmacology. It is an inhibitor that binds to ion channels, which are membrane proteins that allow the passage of ions across a lipid bilayer. This product has been shown to be a ligand for peptide and receptor interactions, and activation of these receptors can lead to various biological effects. 1-({[(3-Bromophenyl)methyl]carbamoyl}amino)cyclopentane-1-carboxylic acid is also an antibody activator, which means it can bind to antibodies and activate their immune response functions.