Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-(Tetrahydro-2-furanylmethoxy)-1-ethanol is a monoglyceride with a 2-hydroxy group and an ether bond. It is a glycol ether and glycol ester, which are used in the manufacture of polymers and adhesives. 2-(Tetrahydro-2-furanylmethoxy)-1-ethanol is also known to be metabolized in the human body to methyl ethyl, which has been shown to have neurotoxic effects. The substance has been shown to cause locomotor activity in mice at a dose of 100 mg/kg. It is also known to inhibit the activity of the receptor that binds acetylcholine, thereby decreasing muscle contractions. This product has been shown to cause skin cancer when applied topically in animal studies.

Versatile small molecule scaffold

[(2-Methylprop-2-en-1-yl)oxy]benzene is a diphenyl ether with the chemical formula C9H14O. This molecule has a hydroxy group, which is an inorganic acid, and a chloride group. [(2-Methylprop-2-en-1-yl)oxy]benzene is used as a polymerization initiator for plastics and resins. It also has functional groups that are involved in receptor activity and can be used to synthesize different types of organic molecules.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

3-Bromobutan-2-ol is an alcohol that is used as a chemical intermediate in the preparation of bromohydrins, which are intermediates in the production of other organic compounds. 3-Bromobutan-2-ol can be prepared by catalytic asymmetric synthesis from 2-bromoethanol and dimethylamine. The stereoisomers of 3-bromobutan-2-ol are optically active and can be separated by column chromatography or recrystallization. The synthetic route for this compound involves esterification with formic acid followed by hydrolysis to give 3-bromobutanone, which then undergoes a dehydration reaction with boron tribromide to produce 3-bromobutan-2-ol. This product has been shown to have antifungal properties against Candida albicans, Coccidioides immitis, and Aspergillus fumigatus

Versatile small molecule scaffold

Methyl(phenyl)phosphinoyl chloride is a phosphorus-containing compound that is an intermediate in the synthesis of the drug phosphinothioyl chloride. Methyl(phenyl)phosphinoyl chloride is used in the treatment of hepatitis, but it also has antiviral properties. The enantiomers of methyl(phenyl)phosphinoyl chloride have different effects on viruses. The left-handed enantiomer inhibits RNA polymerase and other enzymes involved in virus replication, while the right-handed enantiomer blocks virus assembly. Magnetic resonance spectroscopy (MRS) analysis has shown that the left-handed enantiomer binds to the receptor for growth factor, which may account for its antiviral activity.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Beta-alanine tert-butyl ester hydrochloride is a hydrogenated beta-amino acid ester that is used as a peptidomimetic. It has been shown to be absorbed by the intestine and it can be used to focus on chloride channels in the intestinal cells. Beta-alanine tert-butyl ester hydrochloride is an organic solvent and can also be used as an excipient for drug formulations. The molecule has a benzyl group and a chloride group, which are both substituted with hydrogen atoms.

Versatile small molecule scaffold

Versatile small molecule scaffold