Building Blocks

<p>6-Amino-5-bromopyrimidine-2,4(1H,3H)-dione (6ABPD) is a purine derivative that functions as an inhibitor of phosphorylase kinase. It has been shown to inhibit tumor growth in vivo and in vitro and is used as a therapeutic agent for the treatment of cancer. 6ABPD inhibits the production of phosphorylase kinase by binding to the enzyme's active site with noncompetitive inhibition. Inhibition of phosphorylase kinase leads to a decrease in the levels of ATP and thus decreases the availability of substrates for tumor cell growth and proliferation. 6ABPD also binds to thymidine kinase and inhibits its activity, which may account for some of its antitumor effects.</p>

<p>6-N-Biotinylaminohexanol is a fine chemical that is used as a reagent or as a speciality chemical in research. This compound has also been shown to be a versatile building block for the synthesis of complex compounds and useful scaffolds for medicinal chemistry. 6-N-Biotinylaminohexanol is soluble in organic solvents, such as alcohols and ethers, but insoluble in water. It can be used as an intermediate in organic synthesis or as a reactant for the preparation of other chemicals.</p>

<p>2-Amino-6-bromopyrazine is a versatile building block that can be used in the synthesis of complex compounds. It is also used as a reagent, speciality chemical and useful scaffold for the synthesis of pharmaceuticals and other chemicals. 2-Amino-6-bromopyrazine is available from Sigma Aldrich with CAS No. 54237-53-5.</p>

<p>3,4-Dichloro-2-methylpyridine is a novel sulfur analogue that has been shown to have significant antitumor activity in breast cancer xenografts. 3,4-Dichloro-2-methylpyridine inhibits the growth of tumor cells by binding to their DNA and inhibiting RNA synthesis. It also inhibits the production of reactive oxygen species and stabilizes cell membranes. 3,4-Dichloro-2-methylpyridine has been found to be active against human tumors in vivo and is a potential anticancer drug for human use.</p>

<p>1,2-Dibromo-2,4-dicyanobutane is a chemical substance with antimicrobial properties. It is used as an ingredient in the production of health care products and preservatives for food. 1,2-Dibromo-2,4-dicyanobutane inhibits bacterial growth by preventing the synthesis of fatty acids and proteins. This compound has been shown to have synergistic effects when combined with benzalkonium chloride or potassium dichromate. 1,2-Dibromo-2,4-dicyanobutane has not been found to be carcinogenic in animal studies and does not cause allergic reactions.</p>