Building Blocks

<p>Applications 4-Iodopyrazole is used in the synthesis of (pyrazolyl)oxobenzocycloheptapyridinyl acetamides that act as inhibitors of c-Met.<br>References Northrup, A. et al.: J. Med. Chem., 56, 2294 (2013);<br></p>

<p>Applications An intermediate for the synthesis of many biologically active molecules including receptor ligands and enzyme inhibitors<br>References Miyashita, A., et al.: Chem. Pharm. Bull., 45, 1235 (1997), Collins, I., et al.: J. Med. Chem., 45, 1887 (2002), Miller, W.H., et al.: Bioorg. Med. Chem. Lett., 13, 1483 (2003),<br></p>

<p>Applications Myristoyl Chloride is a building block that has been used to form esters on rubber wood. Esterification reduces crystalinity of wood and reduces light0induced color changes (phot-yellowing ) at wood surfaces. Myristoyl Chloride has also been used in the modification of isophalate-PEG copolymers to make amphiphilic copolymers as nanocarriers for drug delivery.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Salla, J., et. al.: J. Wood Chem. Tech. , 32, 121 (2012); Gupta, B., et. al.: J. Macromol. Sci. Pure, 48, 1009 (2011)<br></p>

<p>Applications 1-Phenyl-2-pyrrolidone (cas# 4641-57-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-BROMO-1-PHENYLPROPANE (cas# 2114-39-8) is a useful research chemical.<br></p>

<p>Applications m-Toluoyl Chloride is used as a reagent in the synthesis of glycine benzamides as oral GPR139 receptor agonists. m-Toluoyl Chloride is also used in the preparation of colchicine derivatives which have potent anticancer activity and reduced P-glycoprotein induction liability.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dvorak, C.A., et al.: ACS Med. Chem. Lett., 6, 1015 (2015); Singh, B., et al.: Org. Biomol. Chem., 13, 5674 (2015)<br></p>

<p>Applications Diisopropyl Malonate is a disinfection byproduct of Isoprothiolane (I874300); a dithiolane pesticide commonly used in agriculture as a fungicide to control planthoppers and blast disease in rice plants.<br>References Chin, K.M.: Malay. Agric. J., 50, 221 (1975); Ikeda, Y. et al.: Biosci. Biotech. Biochem., 57, 288 (1993); Nakamura, H.: Rev. Plant Prot. Res., 10, 1 (1977); Reddy, A.P.K. et al.: Pesticide, 22, 21 (1988); Jinno, H., et al.: Arch. Toxicol., 71, 550 (1997)<br></p>

<p>Applications Diaminomaleonitrile is a reagent used for the synthesis of 1,4-diazepine-2,3-dicarbonitrile dervatives. Also, it is used for the synthesis of Diaminomaleonitrile-based Schiff bases with a donor-acceptor structure and an aggregation-enhanced emission feature.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wieczorek, E., et al.: Tetrahedron Lett., 58, 758-761 (2017); Han, T., et al.: J. Mater. Chem. C Mater. Opt. Electron Devices, 4, 10430-10434 (2016);<br></p>

<p>Applications N-(Benzyloxycarbonyl)-4-piperidone<br></p>

<p>Applications Pyridine hydrobromide (cas# 18820-82-1) is a useful research chemical.<br></p>

<p>Applications (4-Fluorophenyl)hydrazine, HCl<br></p>

<p>Applications rac-Trifluorolactic Acid is a derivative of DL-Lactic Acid (L113490) which occurs in small quantities in the blood and muscle fluid of man and animals. The lactic acid concentration increases in muscle and blood after vigorous activity.<br>References He, W. et al.: Comp. Biochem. Phys. Part A: Mol. Int. Phys., 166, 308 (2013)<br></p>

<p>Applications N-Ethylethylenediamine<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Diphenyl Chlorophosphonate, is a building block used for the synthesis of various chemical compounds. It can be used for the synthesis of phosphate esters of polyhedral hydroxyboranes, showing enhanced tumor uptake.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bechtold, R., et al.: J. Med. Chem., 18, 371 (1975);<br></p>

<p>Applications 5-Bromo-2-nitropyridine is employed as a reagent in the synthesis of novel benzinidazoles, potent inhibitors of TIE-2 and VEGFR-2 Tyrosine (T899975) kinase receptors.<br>References Hasegawa, M., et al.: J. Med. Chem., 50, 4453 (2007); Okaniwa, M., et al.: J. Med. Chem., 55, 3452 (2012)<br></p>

<p>Applications 3-BENZYLADENINE (cas# 7280-81-1) is a useful research chemical.<br></p>

<p>Applications (Ethane-1,2-diylbis(oxy))bis(ethane-2,1-diyl) bis(4-methylbenzenesulfonate) (cas# 19249-03-7) is a useful research chemical.<br></p>

<p>Applications Ethyl Cyano(ethoxymethylene)acetate is an intermediate in the synthesis of anti-inflammatory agents with gastroprotective effect in rats.<br>References Karoui, A., et al.: Med. Chem. Res., 23, 1591 (2014);<br></p>

<p>Applications trans-2-Pentenoic Acid has been used in preparation of new nonsteroidal human androgen receptor (hAR) agonists from an hAR antagonist pharmacophore, 2(1H)-piperidino[3,2-g]quinolinone.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zhi, L., et al.: Bioorg. Med. Chem. Lett., 9, 1009-1012 (1999)<br></p>