Building Blocks

<p>Applications 2-Bromoethylamine Hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist.<br>References Shi, D., et al.: J. Med. Chem., 44, 4509 (2001); Rami, H., et al.: Bioorg. Med. Chem. Lett., 16, 3287 (2006)<br></p>

<p>Stability Moisture Sensitive<br>Applications 2-Bromoacetyl Bromide, is a builidng block used for various organic synthesis. It can be used for the synthesis of novel biofunctional molecules for target-selective photodegradation of proteins and carbohydrates.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Toshima, K., et al.: Yuki Gosei Kagaku Kyokaishi, 70, 1187 (2012);<br></p>

<p>Applications Decanoyl Chloride is used in the synthesis of an effective metalloproteinase inhibitor. Also acts as a reagent in the synthesis of reversible α-ketoheterocycle inhibitors of fatty acid amide hydrolase as potnetial analgesics.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Levy, D. et al.: J. Med. Chem., 41m 199 (1998); Boger, D. et al.: J. Med. Chem., 48, 1849 (2005);<br></p>

<p>Applications Phenyl 2-Chloroethyl Ether (cas# 622-86-6) is a compound useful in organic synthesis.<br></p>

<p>Applications Ethyl Carbazate is used in the synthesis of P1 aryl heterocycle-based thrombin inhibitors. It can be also used to prepare diazenedicarboxamides as inhibitors of alanylalanine ligase.<br>References Young, M., et al.: J. Med. Chem., 47, 2995 (2004); Kovac, A., et al.: Bioorg. Med. Chem. Lett., 17, 2047 (2007)<br></p>

<p>Applications Methoxyacetaldehyde Dimethyl Acetal is a reagent used in balancing oral exposure with Cyp3A4 inhibition in benzimidazole-based IGF-1R inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Zimmermann, K., et al.: Bioorg. Med. Chem. Lett., 18, 4075 (2008);<br></p>

<p>Applications 2,5-DIMETHOXYTETRAHYDROFURAN (cas# 696-59-3) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Myristoyl Chloride is a building block that has been used to form esters on rubber wood. Esterification reduces crystalinity of wood and reduces light0induced color changes (phot-yellowing ) at wood surfaces. Myristoyl Chloride has also been used in the modification of isophalate-PEG copolymers to make amphiphilic copolymers as nanocarriers for drug delivery.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Salla, J., et. al.: J. Wood Chem. Tech. , 32, 121 (2012); Gupta, B., et. al.: J. Macromol. Sci. Pure, 48, 1009 (2011)<br></p>

<p>Applications An intermediate of pyridinyl pyrrole compounds as proton pump inhibitors with improved gastric acid secretion suppressive activity.<br>References Tomasi, J., et al.: Chem. Rev., 105, 2999 (2005), Godula, K., et al.: Science, 312, 67 (2006), Davies, H., et al.: Nature, 451, 417 (2008),<br></p>

<p>Applications A substituted alkynyl phenoxy compound as new synergists in pesticidal compositions.<br>References Hefner,T., et al.: Bioorg. Med. Chem., 10, 1731 (2002),<br></p>

<p>Applications N-Hydroxy-1-oxy-nicotinamidine is an intermediate in the synthesis of rac-Arimoclomol Maleic Acid (A771275), which is a potential antidiabetic agent used for the treatment of insulin resistance.<br>References Kurthy, M., et al.: PCT Int. Appl. WO 2000050403 A1 20000831. Aug 31, 2000; Kuerthy, M., et al.: Hung. Pat. Appl. HU 2000000552 A2 20011228. Dec 28, 2001<br></p>

<p>Applications Sodium 4-methylbenzenesulfinate (cas# 824-79-3) is a useful research chemical.<br></p>

<p>Applications 4-Benzyloxybenzoic Acid is a chemical reagent in the preparation of anticancer leads such as quinolin-4-one derivatives.<br>References Cheng, Y. et al.: Bioorg. Med. Chem. Lett., 23, 5223 (2013);<br></p>

<p>Applications 2-hydrazino-1-methyl-1H-benzimidazole hydrochloride (cas# 114804-55-6) is a useful research chemical.<br></p>

<p>Applications 3-Chlorophenylboronic acid is a useful research chemical, a useful reagent for Suzuki-Miyaura cross-coupling reactions.<br>References Savitha, B., et al.: J. Heterocycl. Chem., 55, 2277 (2018); Liu, K., et al.: Eur. J. Org. Chem., 34, 4769 (2018)<br></p>