Building Blocks

Applications 3-Cyanopyridine is used in the preparation of arylthiazolines and arylimidazolines via dibromodimethylhydantoin-catalyzed condensation of aryl nitriles with ethylene diamine or aminoethanethiol.
References Hojati, S. F., et al.: Can. J. Chem., 88, 135 (2010);

Applications Guanidinoacetic Acid is an important marker for renal failure, in kidney transplantation, and for the renal metabolic activity.
References Zugno, A., et al.: Neurochem. Res., 33, 1804 (2008), Debray, F., et al.: Neurol., 71, 44 (2008), da Silva, R., et al.: Am. J. Physiol., 296, E256 (2009),

Stability Unstable in Aqueous Solution
Applications 4-Amino-1-butanol is used in the synthesis of NSAIDs with anti-inflammatory properties. Also used in the synthesis of polyamine transport ligands with specificity against human cancers allowing easy access to specific cancer cells.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Majumder, J. et al.: Langmuir, 29, 10254 (2013); Muth, A. et al.: J. Med. Chem., 56, 5819 (2013)

Stability Moisture Sensitive
Applications 5-Bromoacetyl-2-hydroxybenzamide is a reagent used in the synthesis of bisthiazole derivatives and novel 7-methylguanine derivatives targeting influenza polymerase binding domains.
References Pautus, S. et al.: J. Med. Chem., 56, 8915 (2013); Araniciu, C. et al.: Revista. Chim., 64, 1067 (2013);

Applications Chloroquinolines block antibiotic efflux pumps in antibiotic-resistant Enterobacter aerogenes isolates.
References Canton, R., et al.: J. Clin. Microbiol., 40, 1237 (2002), Yu, E., et al.: Science, 300, 976 (2003), Chollet, R., et al.: Antimicrob. Agents Chemother., 48, 2518 (2004), Li, X., et al.: Drugs, 64, 159 (2004),

Applications Used as a reagent for the synthesis of acridine (A190900) derivatives and fibrinogen receptor antagonists.
References Yang, D. et al.: Macromol., 35, 5304 (2002); Harrison, R.J. et al.: Bioorg. Med. Chem. Lett., 9, 2463 (1999);

Applications 4-Amino-2-chloro-3-methylbenzonitrile is a reagent used in synthesis of imidazolin-2-ones, which is designed and synthesized as highly potent, orally active and muscle selective androgen receptor modulators (SARMs).
References Li, J. J., et al.: J. Med. Chem., 50, 3015-3025 (2007)

Applications 4-Fluorobenzoic Acid Methyl Ester, is an organic fluorinated building block used for the synthesis of various pharmaceutical compounds. It can be used for the preparation of Blonanserin (B595850).
References Wang, J., et al.: Zhongguo Yiyao Gongye Zazhi, 40, 247 (2009);

Stability Explodes When Heated
Applications 2-Cyanoethyl N,N,N’,N’-Tetraisopropylphosphoramidite (cas# 102691-36-1) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 1-Methyl-1h-1,2,4-triazol-3-amine (cas# 49607-51-4) is a useful research chemical.

Applications 1-(4-Amino-3,5-dichlorophenyl)-2-ethanone (cas# 37148-48-4) is a compound useful in organic synthesis.

Applications An intermediate in the production of many biological inhibitors.
References Lambertucci, C., et al.: Bioorg. Med. Chem., 17, 2812 (2009), Lebsack, A., et al.: Bioorg. Med. Chem. Lett., 19, 40 (2009), Griffith, D., et al.: J. Med. Chem., 52, 234 (2009),

Applications Tris(2-(2-methoxyethoxy)ethyl)amine (cas# 70384-51-9) is a useful research chemical.

Applications 2-Chloro-N-(hydroxymethyl)acetamide is an organic building block, and an amidomethylating reagent.
References Haridas, A. K., et al.: RSC Adv., 4, 12188 (2014); Teramoto, K., et al.: Polym. J., 34, 363 (2002)