Building Blocks

<p>Versatile small molecule scaffold</p>

6,8-dimethyl-3H,4H-imidazo[1,5-a][1,3,5]triazin-4-one is a cytotoxic compound that binds to chloride anions in the cell membrane and causes disruption of the ionic equilibrium. It also binds to human cells by coordinating with the anionic sites on the cell surface. This drug has been shown to inhibit growth and induce apoptosis in bladder cancer cells. 6,8-Dimethyl-3H,4H-imidazo[1,5-a][1,3,5]triazin-4-one also inhibits tumor growth in mice transplanted with human bladder cancer cells. The drug works by binding to DNA bases and causing crosslinking of DNA chains. This leads to inhibition of RNA synthesis and protein synthesis.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-[(Pyridin-3-ylmethyl)-amino]-ethanol is the methanol analogue of the coordination compound 2-[(pyridin-2-ylmethyl)-amino]-ethanol. The molecule has a chain structure, with two coordination bonds and a total of six atoms. It is a dimeric molecule that can be polymerized to form polymers. The structure is metallic with antiferromagnetic coupling between the two metal centers, which can be assembled into larger structures. This compound interacts with other molecules at the coordinated sites where it binds. Magnetism results from the unpaired electron spins on each metal center and from spin-spin interactions between these centers.</p>

<p>9-Ethyl-9H-carbazole-3,6-dicarbaldehyde (9ECDA) is a fluorescent molecule that has been shown to have anticholinesterase activity. This compound is being developed for the treatment of cervical cancer and other cancers. 9ECDA is synthesized by reacting 2,4,5,6-tetrafluorobenzaldehyde with excess ethyl acetoacetate in the presence of sodium methoxide. 9ECDA can be used as a fluorescent probe for the detection of anions in water. This compound also has optical properties that are dependent on its anion conjugation state. The fluorescence of 9ECDA is quenched when it binds to butyrylcholinesterase and other anionic binding sites.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>(3-Bromothiophen-2-yl)methanol is a reactive, hydrocarbon group that can be used in the synthesis of natural products. It is a synthetic product, and it has been shown to react with sulfur to form a molecule. (3-Bromothiophen-2-yl)methanol is an innovative, natural product that can be used in the synthesis of polymers. This product also reacts with ammonia to form a tetracyclic compound. The optical properties of (3-bromothiophen-2-yl)methanol are recording and hydrocarbon.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>