Building Blocks

<p>3-Chloro-5-nitrobenzoic acid is a potent antiparasitic drug that has been shown to be effective against filarial worms. It is metabolised in the liver to its active form, which inhibits the parasite's ability to produce ATP. 3-Chloro-5-nitrobenzoic acid has been found to be toxic at high doses and can also cause allergic reactions. This drug has been studied as a potential treatment for brugia, due to its structural similarities with benzamides and amides. The structures of analogues of 3-chloro-5-nitrobenzoic acid have been studied and they have shown promising results in gerbils infected with acanthocheilonema.</p>

<p>4-Oxo-4H-pyrido[1,2-A]pyrimidine-3-carboxylic acid is a compound that has an analogy with the structure of pyridoxine. The structure of this molecule includes an alkoxycarbonyl group, a cycloalkyl group, and a phenyl group. This compound can be used as a medicine for gastroprotective purposes, and it also has anti-inflammatory properties. It is believed that 4-Oxo-4H-pyrido[1,2-A]pyrimidine-3-carboxylic acid can be used as a medicament to treat gastric ulcers.</p>

<p>Versatile small molecule scaffold</p>

6,7,8,9-Tetrahydro-5H-benzo[7]annulen-6-one is an underserved drug candidate for tuberculosis. 6,7,8,9-Tetrahydro-5H-benzo[7]annulen-6-one has been shown to be a potent inhibitor of bacterial lactamase enzymes that are involved in the resistance of bacteria to many antibiotics. 6,7,8,9-Tetrahydro-5H-benzo[7]annulen-6-one is also able to bind to the electron withdrawing group on the lactam ring and stabilize the molecule. This binding prevents conformational changes in the lactamase enzyme and inhibits its activity. 6,7,8,9 tetrahydro 5H benzo[7]annulen 6 one has been shown to have potential use in treating tuberculosis due to its activity against drug resistant bacteria

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Methyl 4-nitro-3-phenylbutanoate is a nitro compound that is used as a reagent for the silylation of phenols. It is also used in the synthesis of functionalized aliphatic nitro compounds and has been found to be able to eliminate certain nitrosamines. Methyl 4-nitro-3-phenylbutanoate is an aliphatic, nitro compound with conjugated stereochemistry.</p>

<p>Pentamethylphenylacetonitrile (PMP) is an aldehyde that is used as a reagent in the synthesis of other chemical compounds. It is also used in the preparation of phase transfer catalysts. PMP is typically available as a white powder and can be dissolved in organic solvents such as acetone or benzene. The chemical properties of PMP are similar to those of other aldehydes, including its susceptibility to oxidation, which can lead to the formation of carboxylic acids.</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

1-Ethyl-1H-benzoimidazole-2-carbaldehyde is a nonspecific heteroaromatic compound that has been shown to be sensitive to solvation. The conformers of this molecule have been determined by intramolecular sensitivity and regression analysis. This molecule is an intramolecular heteroaromatic compound with an electronic transition. The conformers are determined by the polarizability and electronic transitions of the molecule. This molecule has solvatochromism, which is a change in color due to changes in solvent polarity. 1-Ethyl-1H-benzoimidazole-2-carbaldehyde has been shown to exhibit conformational changes in response to changes in temperature, pressure, or solvent conditions, which can lead to changes in its physical properties such as color and melting point.

Ethylene Glycol Mono(4-bromophenyl) Ether is an organic compound with the chemical formula C6H5BrOCH2. It is a colorless liquid, which can be obtained by reacting benzophenone with magnesium in diethyl ether. It is used to synthesize organolithiums and organomercurials. Ethylene Glycol Mono(4-bromophenyl) Ether can be prepared by reacting naphthalene with mercuric chloride. The product is obtained as a white solid or crystalline powder after crystallization from ethanol.

<p>2-(2-Bromophenoxy)ethanol is a primary alcohol that can be used as a probe in enzymatic reactions, such as the ring-opening of pyridinium salts. It reacts with nucleophilic compounds to form lactams, which are macrocyclic molecules. 2-(2-Bromophenoxy)ethanol can also be used to synthesize epoxides and alcohols.</p>

Versatile small molecule scaffold