Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-(3-Bromophenyl)oxirane is a reactive intermediate which has been studied as a potential neuropharmacological agent. It is a strain of the drug carbamazepine and an epoxide surrogate of sulfinyl. 2-(3-Bromophenyl)oxirane has been shown to be deuterated at the α-carbon position, allowing for reproducible and high concentrations in experiments. The deuterated version can be used to determine the metabolic fate of drugs, such as dopamine.

Versatile small molecule scaffold

Versatile small molecule scaffold

6-Ethyltetrahydro-2H-pyran-2-one is a monatomic chemical in the diptera family. It is used as a detection method for host plants, and has been found to be present in fatty acids of coatings and analytical chemistry. 6-Ethyltetrahydro-2H-pyran-2-one can also be found in cuticular hydrocarbons and viscosity. The fluorescence of this compound is an analytical method that can be used to identify it. This chemical has also been shown to have antiviral properties, which are due to its ability to induce the expression of genes involved in the production of aldolases.

9-Methylfluorene-9-carboxylic acid is an organic compound that has a benzyl group attached to the 9th carbon of the fluorene ring. It is a colorless solid with a melting point of -78.5 °C. The synthesis of this compound involves the reaction of 9-fluorenone with diethyl ether in the presence of formic acid and phosphorous pentoxide. This reaction results in the formation of 9-methylene-9-fluorene, which is then oxidized to form 9-methylanthracene. Finally, methanol is added to form 9-methylfluorene-9-carboxylic acid. The molecular weight for this compound is 152 g/mol and it has an mp at -78.5 °C and bp at 138 °C. This compound can be used as a fingerprinting agent due to its characteristic UV absorption spectrum, which peaks

Ethyl cyclohexanecarboxylate is an anti-inflammatory drug that belongs to the class of hydroxylated glycol ethers. It has been shown to have a significant effect on autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis. The active form of ethyl cyclohexanecarboxylate is metabolized through nitro reduction by cytochrome P450 enzymes, which are present in most mammalian tissues. This drug also has a high phase transition temperature and can be used as a catalyst for organic reactions at low temperatures. Ethyl cyclohexanecarboxylate has been shown to inhibit dpp-iv (dipeptidyl peptidase IV), which is an enzyme that cleaves the dipeptides from the N-terminal ends of proteins, leading to increased levels of fatty acids and other alkanoic acids in the blood.

Versatile small molecule scaffold

Versatile small molecule scaffold

Ethyl 4-oxohexanoate is an organic compound that is a dicarboxylic acid. It is used in the synthesis of esters and lactones. Ethyl 4-oxohexanoate undergoes decarboxylation to produce diethyl succinate. This reaction can be accelerated by heating ethyl 4-oxohexanoate with a catalyst such as calcium oxide, giving evolution of carbon dioxide gas. Hydrolysis of ethyl 4-oxohexanoate produces ethyl acetate as well as ethanol, which are both volatile liquids at room temperature.

Versatile small molecule scaffold

Versatile small molecule scaffold

Piperidin-1-yl-acetic acid hydrochloride is a labile, medicinal compound that is effective at low doses. It is used to treat hypercholesterolemia and inflammation. Piperidin-1-yl-acetic acid hydrochloride is an organic compound that belongs to the group of carboxylic acids. The molecule can exist in two different forms, which are called anomers: alpha and beta. The alpha form is more stable than the beta form and has higher medicinal properties. Piperidin-1-yl-acetic acid hydrochloride lowers cholesterol levels by inhibiting its synthesis.

Versatile small molecule scaffold

N-(2-Phenylethyl)hydroxylamine (NPEHA) is an antidiabetic agent that is a member of the class of amides. It has been shown to inhibit the transcriptional regulation of metabolic rate and physiological activities. NPEHA binds to the dopamine receptor and may be useful in treating Parkinson’s disease. NPEHA also inhibits cancer cell growth by binding to the lps-stimulated raw264.7 cells, which are a type of mouse macrophage cell line. The hydrogen bond between the hydroxyl group and the nitrogen atom on NPEHA is critical for its activity as an antidiabetic agent.