Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Methylisothiazole-5-carboxaldehyde is a potent antiviral agent that has been shown to be active against human viruses in vitro. It has also been shown to have an inhibitory effect on the infectivity of influenza virus in mice. 3-Methylisothiazole-5-carboxaldehyde prevents the virus from penetrating the cell membrane, thereby preventing viral replication and inhibiting the release of new viruses into the host. This compound can be used as a chemotherapeutic agent for respiratory infections because it is orally bioavailable and inhibits viral replication.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Pyrimidine-2-carboxamide is an amide that has been shown to have antiinflammatory activity. It has been clinically studied for the treatment of diabetic neuropathy, inflammatory bowel disease, and autoimmune diseases. Pyrimidine-2-carboxamide inhibits the production of proinflammatory cytokines by inhibiting hydrogen bond formation between the amide group and DNA bases. This compound also has a number of other biological activities, including antiviral effects against HIV infection and cancer. Pyrimidine-2-carboxamide is a chemotherapeutic agent that has been used in clinical trials for bladder cancer and bowel disease.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Methoxymethyl)benzoic acid is a natural product that has been shown to have antibacterial activity. It is an ethylene precursor and is synthesized by the alkaline hydrolysis of 2-hydroxybenzoic acid. 2-(Methoxymethyl)benzoic acid has been shown to inhibit the growth of bacteria, such as E. coli, in the presence of hexanoic or octanoic acids. This compound also inhibits the growth of other bacterial species, including lamiaceae and eugenol, at low concentrations. The inhibitory effect may be due to its ability to bind to hydrophobic sites on bacterial cell membranes. 2-(Methoxymethyl)benzoic acid acts as a phenolic compound with a hydrocarbon group.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Ethyl 2-(carbamoyloxy)benzoate (EMCB) is a prodrug that is hydrolyzed in vivo to the active form, fenoprofen. It has been shown to inhibit prostaglandin synthesis and to have analgesic, antipyretic, and anti-inflammatory properties. EMBC inhibits the enzyme cyclooxygenase which converts arachidonic acid into prostaglandins. In humans, EMBC is absorbed from the gastrointestinal tract and excreted in the urine unchanged or as metabolites. The drug has been found to be effective against activated platelets and plasma albumin, but not against intestinal enzymes such as ileal or pancreatic amylases. EMBC also has contraceptive properties and can be used as an oral contraceptive for up to three months at a time. EMBC may interact with other drugs that are broken down by cytochrome P450 enzymes, including acetylsalicylic acid and corticoster</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1H-Imidazole-4-carboxaldehyde, 2-ethyl-5-methyl-, is a mononuclear ligand that can be immobilized on magnetic plates. It has been used in catalytic studies of transition metal complexes and unsymmetrical architectures. The ligand has been shown to have a strong magnetic moment with two methyl groups on the nitrogen atoms that are capable of coordinating to metal ions. This ligand has been studied using several crystallographic methodologies, including X-ray diffraction, electron diffraction, and NMR spectroscopy.<br>The polymorphs of this compound include trigonal bipyramidal (P3) and cubic (Fd3m).</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 5-nitrothiophene-3-carboxylate is a dienophile that reacts with electron-rich diene compounds to form substituted benzothiophenes by the Diels-Alder reaction. The electron acceptor in this reaction is the diene, and the electron donor is methyl 5-nitrothiophene-3-carboxylate. The selectivity of this reaction can be controlled by altering the substitution pattern on the diene. The cycloaddition product is a monocyclic system containing four fused rings and one unsaturated bond. This product is also known as an indanone.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>7-Methoxybenzo[b]thiophene-2-carboxylic acid is a condensation product that can be formed by reacting chloramine with 2-hydroxy-3-methoxybenzaldehyde. This compound can also be produced by demethylation of 7-methoxybenzo[b]thiophene, decarboxylation of 7-methoxybenzo[b]thiophene, and nitration of 7-methoxybenzo[b]thiophene. The reaction of this compound with thiols produces the corresponding 3,4,5,6-tetrahydrobenzothiazoles. Bromination followed by hydrolysis produces benzo[b]thiophenesulfonic acid and bromine.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 3-amino-3-phenylpropanoate hydrochloride is a carboxamide that can be synthesized by the reaction of an amine with methyl 3-hydroxybutanoate. The compound can exist as three tautomers, two of which are enolates. The compound has been shown to undergo hydrogen bonding in its crystal structure and has been characterized by NMR spectroscopy. Methyl 3-amino-3-phenylpropanoate hydrochloride is a precursor to other compounds such as 6-alkyl, 4-hydroxy, and amides.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-(Aminomethyl)furan-2-yl]methanol (AFM) is a signalling molecule that is used in the study of heterologous expression. It has been shown to be more potent than the natural growth factor, TGF-β, and has been found to induce corneal endothelium cell proliferation. AFM is also a degradable molecule with l-amino acid side chains. The degradation of AFM can be inhibited by erythromycin.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>