Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>2-[(Prop-2-yn-1-yl)amino]acetic acid hydrochloride (PAH) is a molecule that is being studied for its potential as a broad-spectrum antimicrobial. PAH has been shown to inhibit the growth of bacteria, fungi, and viruses by binding to the ATP channel on the mitochondrial membrane. This binding inhibits ATP synthesis and prevents cell division. PAH also has antimicrobial activity against Gram negative bacteria through a mechanism that is not yet known. PAH has been shown to decrease muscle cell proliferation in rats by inhibiting protein synthesis and increasing apoptosis. PAH is synthesized from propionic acid and acetamide via asymmetric hydrogenation, which can be accomplished using an organocatalyst such as palladium on carbon or nickel on carbon.</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>2-Methyl-3-(thiophen-2-yl)propanoic acid is a mucolytic agent that belongs to the group of benzoic acid derivatives. It is used as an expectorant and mucolytic drug. This drug has been shown to dissolve mucus in the airways, which may be due to its ability to inhibit the activity of glycosidases.</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>3-(4-Fluorophenoxy)propan-1-ol is a modification of the parent compound, 3-phenoxypropan-1-ol. The modification is atypical and has been shown to have anti-cancer properties. In addition, this compound has been shown to be an aromatase inhibitor, which prevents the conversion of androgens into estrogens. This may be due to its ability to inhibit the enzyme's activity on substrates such as dopamine, dimethylformamide, or evaporation. 3-(4-Fluorophenoxy)propan-1-ol has also been shown to have serotonin receptor binding profiles that are similar to those of phenoxy compounds such as butyrophenone or piperidine.</p>

<p>Versatile small molecule scaffold</p>

<p>3,5-Dichloro-2-hydrazinylpyridine is a pyridine derivative that is synthesized by the condensation of pyrazoles with β-unsaturated carbonyl compounds. It is also used as an intermediate for the synthesis of pyrazole derivatives. The compound can be prepared by reacting acetoacetic esters and hydrazine. 3,5-Dichloro-2-hydrazinylpyridine has been shown to interact with pyrazoles, which are intermediates in its synthesis. Pyrazoles are also produced when 3,5-dichloro-2-hydrazinylpyridine reacts with β-unsaturated carbonyl compounds.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>3-Methoxy-4-propoxyaniline is a chemical compound that belongs to the group of diphenyl ethers. It is used as an insecticide and has shown to be effective against larvae of certain species of Diptera, including Musca domestica. 3-Methoxy-4-propoxyaniline inhibits the synthesis of chitin, leading to the death of insects. 3-Methoxy-4-propoxyaniline has been shown to have a high resistance in vivo and in vitro tests with metarhizium, as well as being effective against other fungi such as Aspergillus niger and Penicillium notatum. This compound can also be found in some plants, such as garlic and onions, where it acts as an alliinase inhibitor.</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

4-Amino-2-(hydroxymethyl)benzenol is a multilayer, which is synthesized in the copper complex. It has synergistic effects with amodiaquine, and can be used to treat blastomycosis. The parameters of 4-Amino-2-(hydroxymethyl)benzenol are dependent on the conditions where it was synthesised.

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>3-Hydroxybenzene-1-carbothioamide is a methanol derivative that is used to measure the concentration of thiobenzamide in solution. It has a linear calibration curve and can be used in reversed-phase, photometric, and chloride ionization modes. 3-Hydroxybenzene-1-carbothioamide is stable at least for 6 months when stored at room temperature. This compound can be used as an alternative to 3-(2-carboxyethyl)-5,6-dihydrothiazole (TCET) as it has been shown to give similar results with a reproducible response time.</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

4-Methyl-N-(propan-2-yl)aniline hydrochloride is a synthetic compound that has been shown to have an inhibitory effect on ion channels, especially the sodium channel. It is used as a research tool and has been shown to activate certain receptors and to be an inhibitor of ligand activation.