Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Hydroxy-3,3-dimethylbutanoic acid is an organic compound that is used as a precursor to hypochlorite. It is synthesized by the catalytic oxidation of ethyl formate with a palladium catalyst in an alkaline solution. The resulting 2-hydroxy-3,3-dimethylbutanoic acid has a high yield and can be used as a starting material for the manufacture of sodium hypochlorite and other chlorinating agents. The optical purity of the product can be improved by using ruthenium or copper catalysts in place of palladium.

4-Hydrazinothieno[2,3-d]pyrimidine is an anti-cancer drug that is activated by xylene. It is used in the treatment of bowel disease and cancer. 4-Hydrazinothieno[2,3-d]pyrimidine has been shown to have antibacterial properties against Gram-positive bacteria and may be effective as a topical agent for skin infections. This drug also has platelet activating properties, which are mediated through the p2y12 receptor. This receptor is involved in inflammatory bowel disease, as well as other tissues such as the brain and heart. 4-Hydrazinothieno[2,3-d]pyrimidine may be useful in treating cancer because it inhibits the production of TNF-α (tumour necrosis factor alpha) which leads to tumor growth inhibition.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Methyl 3-formyl-5-methoxybenzoate is a versatile compound with various applications. It is commonly used as a building block in the synthesis of fatty acids, safranal, and other research chemicals. This compound can also be employed in the production of polymers, neonicotinoids, terephthalate, and gabapentin. Additionally, it exhibits pesticidal properties and can act as an anesthetic and antiviral agent. Methyl 3-formyl-5-methoxybenzoate has been found to interact with dopamine receptors and may have potential therapeutic effects. Its diverse range of uses makes it a valuable component in multiple industries.

1-(Azidomethyl)-4-methoxybenzene (1-AMMB) is a copper complex that can be used to induce the irreversible oxidation of organic molecules. 1-AMMB has been shown to be cytotoxic in vitro against MDA-MB-231 cells and MCF-7 cells. It was also shown to have anticancer activity in vivo, inhibiting tumor growth and tumor cell proliferation in mice implanted with human breast cancer cells. The anti-cancer properties of 1-AMMB are attributed to its ability to activate the copper(II) ion, which causes DNA damage by forming covalent bonds with guanine bases. This leads to the inhibition of DNA replication and transcription, which eventually kills the cell.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1,2,3,4,6,7,8,9-Octahydrophenazine is a cyclic ether that is usually obtained by the hydrogenation of diethylene. It is used as a pharmaceutical intermediate. 1,2,3,4,6,7,8,9-Octahydrophenazine has been shown to coordinate with metal ions such as copper and copper chromite. This coordination stabilizes the molecule and prevents decomposition. 1,2,3,4-Octahydrophenazine also has anti-inflammatory properties due to its ability to inhibit prostaglandin synthesis by inhibiting enzyme activity in the cyclooxygenase pathway.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

A 971432 is a molecule that has been shown to be expressed in the brain and is involved in a number of treatments for symptoms of Alzheimer's disease. It also has innovative properties that can help treat other neurodegenerative diseases, such as Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis. The molecule has also been shown to be effective for fertility and oral use.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

The purpose of this study was to examine the association between fluoridated water and the prevalence of obesity in children. The study found that, in areas with a higher percentage of children who drank fluoridated water, there was a significant increase in the prevalence of obesity. It is important to note that fluoride has been shown to have health effects other than dental fluorosis. One such effect is an increase in bone fractures. Fluoride also interacts with physiological processes, such as blood pressure regulation and insulin secretion. This article reviews epidemiological studies that have investigated the association between fluoride exposure and various systemic diseases, including cardiovascular disease and diabetes mellitus type 2.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold