Building Blocks

FPS-ZM1 is a small molecule drug with immunomodulatory and anti-inflammatory properties. It was originally synthesized as an inhibitor of the transcriptional regulator HMG-BOX, which is found in the promoters of genes involved in neuronal death, inflammation, and autoimmune diseases. FPS-ZM1 inhibits the transcriptional regulator HMG-BOX by binding to it, thereby preventing it from interacting with its DNA target. This inhibition leads to decreased expression of proinflammatory genes. The effects of FPS-ZM1 on inflammatory responses have been demonstrated in vitro and in vivo using human cells. In addition, FPS-ZM1 has been shown to inhibit Toll-like receptor (TLR) signaling pathways that are activated by lipopolysaccharide (LPS).

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

3-Methyl-1-phenyl-1H-pyrazole-4-carboxaldehyde is a reactant that can be used in the synthesis of salicylaldehyde and phenyl isocyanate. It reacts with a variety of reagents, including salicylic acid, phenyl isocyanate, and isocyanates to produce high yields. This product also reacts with transaminases to produce pyrazole derivatives.

Methyl 3-chloro-2,2-dimethylpropanoate is a drug that inhibits the sodium-dependent glucose cotransporter. It is used as a pharmaceutical to treat diabetes mellitus type 2. Methyl 3-chloro-2,2-dimethylpropanoate binds to the cotransporter and prevents it from transporting glucose into cells. The stereoisomers of this drug are enantiomers and have opposite effects on the cotransporter.
Methyl 3-chloro-2,2-dimethylpropanoate is also used for other medical purposes such as to prevent kidney damage in children with renal failure and to treat seizures in children with epilepsy.

Versatile small molecule scaffold

3-Carbamimidoyl-1-(3-chloro-4-cyanophenyl)urea is a drug that has been shown to have an inhibitory effect on the growth of malaria parasites in vitro. It has also been shown to be effective against other organisms such as bacteria and fungi, including methicillin resistant Staphylococcus aureus (MRSA). 3-Carbamimidoyl-1-(3-chloro-4-cyanophenyl)urea is typically used with a diluent, which can be either water or ethanol. The drug is insoluble in water but soluble in ethanol, so it must be reconstituted before injection. This drug is targeted to the circumferential region of the parasite by an alkyl substituent that attaches to the erythrocyte membrane surface. 3-Carbamimidoyl-1-(3-chloro-4-

Versatile small molecule scaffold

Versatile small molecule scaffold

1,2,3,4-Tetrazolo[1,5-a]quinoline-4-carbaldehyde is an imidazole derivative with antibacterial activity. It inhibits bacterial growth by binding to the β-unsaturated ketones in the cell wall and preventing their synthesis. 1,2,3,4-Tetrazolo[1,5-a]quinoline-4-carbaldehyde has been shown to be effective against Streptococcus mutans and other organisms. It is also a substrate for chlorination reactions and can be used as a catalyst in organic synthesis reactions.

Methyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)acetate is a benzyl ester that was synthesized by the reaction of chloroformate and methyl ester. Methyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)acetate is a functional group that can be used as a linker in solid phase synthesis. It has been shown to undergo alkaline hydrolysis to produce dicarbonate, yielding high yields. This compound also reacts with benzyl alcohols to form methyl esters, which are important organic compounds.

Versatile small molecule scaffold

Please enquire for more information about 3,4-Difluoro-N,N-dimethylbenzamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

8-Methoxy-6-methylquinolin-4-ol (8MQ) is a mitochondrial substrate that has been shown to have physiological functions in energy metabolism and lysine biosynthesis. 8MQ has been shown to be a potential drug target for the treatment of corynebacterium glutamicum, which produces acid formation. 8MQ also inhibits wild-type strains of bacteria and clinical isolates of HIV. The m2 phenotype is an HIV-1 protein that is essential for viral replication. 8MQ binding to this protein prevents it from binding with other proteins on the surface of the virus, inhibiting its ability to bind with CD4 cells and infect new cells.

Versatile small molecule scaffold

Versatile small molecule scaffold

[(2-Oxo-2-phenylethyl)sulfanyl]acetic acid is a methyl ester that belongs to the class of alpha,alpha-diphenylacetates. It has been shown to be an effective inhibitor of protein synthesis in bacteria and yeast. This inhibition may be due to its ability to inhibit ribosome function by binding to the 30S subunit of bacterial ribosomes. The acid methyl ester form of [(2-Oxo-2-phenylethyl)sulfanyl]acetic acid is also an inhibitor of protein synthesis in bacteria and yeast, but it does not inhibit ribosome function.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

4-Hydroxy-6-nitroquinoline is an amide compound that has shown potential in interferon research. It is a solute with an acid reaction and is commonly spray-dried for ease of use. This compound can be synthesized through a pyrazole-based method and is often found in hydrocarbon mixtures. Its cyano and phenoxy groups make it suitable for applications in semisolid formulations, while its phosphite moiety allows it to be incorporated into matrix composites. 4-Hydroxy-6-nitroquinoline is commonly used in the field of Research Chemicals and has been studied for its interactions with uridine.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold