Building Blocks

Imidazo[4,5-b]pyrazine is a chemical compound that binds to calcium ions and has been used in the treatment of metabolic disorders. The symptoms of imidazopyrazine include fatigue, weight loss, fever, chills, and muscle aches. Imidazopyrazine is also used for the treatment of autoimmune diseases such as rheumatoid arthritis. In vitro assays have shown that it activates macrophages and lymphocytes and may be useful in the treatment of skin lesions caused by an infection. Imidazopyrazine has been found to have pharmacokinetic properties with a half-life of 3 hours when administered orally. This drug has also been shown to have biological activity against rat liver microsomes.

Benzo[d][1,2,3]thiadiazole is a benzothiadiazole with a redox potential of -0.25 V that is stable in the absence of oxygen and light. It can be used to synthesize chemical pesticides by reacting with hydrochloric acid. The reaction mechanism of benzo[d][1,2,3]thiadiazole has been determined using nuclear magnetic resonance spectroscopy and quantum chemical calculations. This compound reacts with hydrogen bond acceptors on the enzyme active site to form covalent bonds. It also interacts with the enzyme's steric environment by forming hydrogen bonds and van der Waals forces. Benzo[d][1,2,3]thiadiazole also emits light when it reacts with nitric oxide in solution.

Dimethylcarbamoylbenzoic acid is an ionic compound that can be categorized as a carboxylic acid. It has been shown to be a competitive inhibitor of acetonitrile-catalysed reactions, with the rate constant (k) of 1.02 x 10 M-1s-1. Dimethylcarbamoylbenzoic acid has also been shown to be an intramolecular nucleophile and is therefore classified as a stepwise reaction. The solvents used in this reaction are ethanol and acetonitrile, which have nonionized and ionized forms respectively.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1-Phenylpentane-2,4-dione is a molecule that absorbs light. It has been shown to be an efficient absorber of solar radiation and has the potential to be used in photovoltaic devices. 1-Phenylpentane-2,4-dione can be used as an electron donor in polymer solar cells because it is able to act as both a chelate and a light absorber. 1-Phenylpentane-2,4-dione can also be used in acetone peroxide based solar cells because it is able to absorb light efficiently. In addition, 1-phenylpentane-2,4-dione may have use as an optical element for positioning systems such as telescopes or cameras.

N-[(4-Bromophenyl)methyl]acetamide is a chemical synthesis of lipase. The synthesis was done in a vessel, and the synthetic pathways were highlighted. The molecule was synthesized using chemistry and biomimetic methods. It was amidated to form its final product. The reaction vessel is palladium-based, which makes it an efficient catalyst for the amidation reaction.

1-(4-Cyclopropoxyphenyl)ethan-1-one is a stable, colorless ether. It is used in the acylation of aromatic or aliphatic compounds and has been shown to undergo acylation reactions with nitric acid, sulfuric acid, or phosphoric acid. This compound can also be cleaved with hydrochloric acid to form propionaldehyde.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

N1-Cyclohexylpropane-1,3-diamine is a potent compound that has been shown to inhibit cholesterol synthesis and mitochondrial membrane potential. This drug also has anti-cancer effects and can be used for the treatment of cancers in which nuclear DNA is affected by light emission. N1-Cyclohexylpropane-1,3-diamine has been shown to have physiological activities such as cell growth inhibition, matrix effect, and intracellular hydrogen release. The drug binds to the enzyme activity site with a coordination geometry that is similar to other inhibitors of cholesterol synthesis. N1-Cyclohexylpropane-1,3-diamine was crystallized from methanol at room temperature and its molecular structure was determined by X-ray diffraction techniques.