Reagenti sintetici

<p>Applications 1,1-Bis(hydroxymethyl)cyclopropane is used in the synthesis of morphine alkaloids. It also serves as an inhibitor of 5-lipoxygenase.<br>References Evans, D.A. et al.: Tetrahedron Lett., 23, 285 (1982); Arai, Y. et al.: J. Med. Chem., 26, 72 (1983);<br></p>

<p>Stability Air Sensitive, Hygroscopic<br>Applications N-1-Naphthylethylenediamine Dihydrochloride, is an organic building block used for the chemical synthesis. It can also be used as highly selective organic fluorescent probe for azide ion.<br>References Sahana, A., et al.: Analyst , 137, 1544 (2012);<br></p>

<p>Applications A potent and specific inhibitor of the Jak-2 tyrosine kinase. In acute lymphoblastic leukemia (ALL) cells which abundantly express JAK-2, AG-490 dose-dependently inhibited DNA synthesis, blocked cell growth and induced apoptosis. AG-490 does not significantly inhibit other kinases such as Lck, Lyn, Btk, Syk and Src. AG-490 is cell permeable and is active in vivo.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Stock, J., et al.: J. Biol. Chem., 267, 19753 (1992), Levitzki, A., et al.: Science, 267, 1782 (1995), Meydan., N., et al.: Nature, 379, 645 (1996), Lu, H., et al.: Drug Metab. Dispos., 31, 572 (2003),<br></p>

<p>Applications Potassium Metabisulfite (2:1) is used as a chemical preservative.<br>References Kuang, Y.T., et. al.: J. Food Process. Pres., 39, 56 (2015)<br></p>

<p>Applications It is an Olefin Metathesis Catalyst for cis-selective ring-opening metathesis polymerization and Z-Selective Olefin Metathesis.<br></p>

<p>Applications Blebbistatin blocked myosin II-dependent cell processes. It blocks cell blebbing rapidly and reversibly. Blebbistatin also rapidly disrupted directed cell migration and cytokinesis in vertebrate cell. Blebbistatin blocks both blebbing and cytokinesis at 50-100µM.[Blebbistatin:a]D= -103 (c= 1.21 CHCl3)(-)-1-Phenyl-1,2,3,4-tetrahydro-4-hydroxypyrrolo[2,3-b]-7-methylquinolin-4-oneBlebbistatin is a selective inhibitor of nonmuscle myosin II; Blebbistatin inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Blebbistatin rapidly and reversibly blocks cell blebbing, and disrupts directed cell migration and cytokinesis in vertebrate cells.<br>References Straight, A.F., et al.: Science, 299, 1743 (2003), Duxbury, M.S., et al.: Biochem. Biophys. Res. Commun., 313, 992 (2004), Kovacs, M., et al.: J. Biol. Chem., 279, 34 35557 (2004)<br></p>

<p>Applications Dexrazoxane is a cardioprotective compound against anthracyclines. It is highly protective in reducing anthracycline-induced cardiotoxicity and extravasation injury. It functions by inhibiting topoisomerase II without inducing DNA strand breaks. Dexrazoxane is a + enantiomer of razoxane.<br>References Walker, D., et al.: Pediatr. Blood Cancer 60,616 (2013); Kang, M., et al.: J. Chemother., 24, 292 (2012); Lipshultz, S., et al.: New England J. Med., 35, 145 (2004)<br></p>

<p>Applications Metol is the hemisulfate salt of 4-Hydroxy-N-methylaniline (H918925), used to synthesize arylidene amino azolones with anticancer activity. It is also used to prepare N-(4-hydroxyphenyl)retinamide analogs with antitumor and apoptosis-inducing activities.<br>References Subtel’na, I., et al.: Bioorg. Med. Chem., 18, 5090 (2010); Mershon, S., et al.: Bioorg. Med. Chem. Lett., 17, 836 (2007)<br></p>

<p>Applications Monomethyl Adipate is a useful synthetic intermediate. It can be used to prepare 1,3,4-thiadiazole hydroxamic acid derivatives as novel histone deacetylase inhibitors which show potential antitumor activities. It can be also used to synthesize mannose-linked biphenylylacetic acid derivatives as novel inhibitors of selectin-mediated cell adhesion.<br>References Guan, P., et al.:Bioorg. Med. CHem., 20, 3865 (2012); Kogan, T., et al.: J. Med. Chem., 41, 1099 (1998)<br></p>

<p>Applications A minor antimicrobial used in veterinary medicine.<br>References Dowling, P.M., et al.: Antimicrob. Ther. Vet. Med., 285 (2006), 4th Edition,<br></p>

<p>Applications MK-0822 is a newly developed bone-targeting dual action pro-drug for osteoporosis and bone metastasis. It is also an inhibitor of cathepsin K, an enzyme involved in bone resorption.<br>References Arns, S., et al.: Bioorg. Medn. Chem., 20, 2131 (2012); Cusick, T., et al., J. Bone. Mineral. Rsch., 27, 524 (2013);<br></p>

<p>Applications Ammonium carbonate is a reagent that is used in the synthesis of D,L-Carbidopa (C175915 which is an inhibitor of aromatic amino acid decarboxylase.<br>References Sletzinger, M., et al.: J. Med. Chem., 6, 101 (1963),<br></p>

<p>Stability Hygroscopic<br>Applications Cerivastatin is a competitive inhibitor of HMG-CoA reductase.<br>References Ness, C.G., et al.: Arch. Biochem. Biophys., 325, 242 (1996), Steinke, W., et al.: Japan. Pharmacol. Ther., 24, Suppl. 9, S1217 (1996),<br></p>

<p>Stability Hygroscopic<br>Applications A deuterated selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993), Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996), Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000),<br></p>

<p>Applications COPPER(II) SULFATE (cas# 7758-98-7) is a useful research chemical.<br></p>

<p>Stability Temperature Sensitive<br>Applications An alkylating and carbamoylating nitrosourea compound. It interacts with DNA, RNA and proteins causing DNA interstrand cross linking which is cytotoxic and leads to apoptotic cell death.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Stahl, et al.: Chem. Res. Toxicol., 5, 106 (1992), Kokkinakis, D.M., et al.: Clin. Cancer Res., 5(11), 3676 (1999), Hickman, M.J., et al.: Proc. Natl. Acad. Sci. USA, 96(19), 10764 (1999),<br></p>

<p>Applications 4-Chloro-3-nitrophenol is degraded by Burkholderia sp. strain SJ98 and utilizes it as sole source of carbon, nitrogen and energy under aerobic conditions. Also it is an intermediate of 8-Hydroxychlorpromazine (H824905), which is a metabolite of chlorpromazine (C424750) which is used as an antiemetic.<br>References Pandey, J., et al.: Appl. Microbiol. Biotechnol., 92, 597-607 (2011); Roth, J., et al.: Comm. Psychopharmacol., 3, 235 (1979); Zhang, Z.: Handbook of Metabolic Pathways of Xenobiotics, 3, 1102 (2014); Anden, N.-E., et al.: Eur. J. Pharmacol., 11, 303 (1970), Curzon, G., et al.: Trends Pharmacol. Sci., 11, 61 (1990)<br></p>

<p>Applications Oxidized Limonene, a common reagent used in the preparation of fragrant compounds.<br>References D'Souza, A., et al.: J. Nat. Prod., 67, 700 (2004), Bergstroem, M., et al.: Chem. Res. Toxicol., 19, 760 (2006), Krishnamurthy, M., et al.: Bioorg. Med. Chem., 16, 6489 (2008),<br></p>

<p>Applications 5-Amino-3-methylisothiazole Hydrochloride (cas# 52547-00-9) is a compound useful in organic synthesis.<br></p>

<p>Applications Strontium Chloride Hexahydrate is used in the preparation of mesoporous strontium titanate thin films.<br>References Mohammadi, M. et al.: J. Coat. Tech. Res., 8, 585 (2011);<br></p>

<p>Applications 3-Bromopyridine-d4 is the isotope labelled analog of 3-Bromopyridine (B686740). Pyridine as novel substrate for regioselective oxygenation with aromatic peroxygenase from Agrocybe aegerita.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Colby, J., et al.: Biochem. J., 165, 395 (1977), Damani, L., et al.: Xenobiotica, 12, 527 (1982), Balzarini, J., et al.: J. Antimicrob. Chemother., 55, 135 (2005),<br></p>

<p>Applications (+)-1,2-Bis((2S,5S)-2,5-diphenylphospholano)ethane is a chiral reagent that is used as a catalyst and also as an enantioselective reagent in synthetic chemistry.<br>References Martin, N.: Electrochem. Soc. Interface, Yang, L., et al.: Eur. J. Org. Chem., 2013, 4434 (2013)<br></p>

<p>Applications 3',5'-Bis(Trifluoromethyl)acetophenone is a reactant that has been used in the preparation of pyrazole carboxamide derivatives with antibacterial and antifungal activity.<br>References Patil, A., et. al.: J. Chem. Pharmaceut. Res., 6, 218 (2014)<br></p>

<p>Applications 3-Bromo-N,N,N-trimethylpropan-1-aminium Bromide is a compound used to prepare novel hydrophilic-hydrophobic block copolymer based on cardo poly(arylene ether sulfone)s with bis-quaternary ammonium moieties for anion exchange membranes.<br>References Dong, X., et al.: J. Membr. Sci., 518, 31-39 (2016);<br></p>

<p>Applications N-Aminohexamethylenimine is a sesquiterpene lactones with anti-hepatitis C virus activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rossini, M., et al.: Lett. Drug. Des. Discov., 9, 881 (2012); Hines, R.N., et al.: J. Pharmacol. Exp. Therap., 214, 88 (1980);<br></p>

<p>Applications Thioisonicotinamide is an impurity of Ethionamide (E890420) with tuberculostatic activity.<br>References Pappalardo, G. et al.: Farm. Ediz. Sco., 22, 808 (1967); Waisser, K. et al.: Cesk.-Slov. Farm., 33, 99 (1984); Devani, M. B. et al.: J. Pharmac. Sci., 43, 1471 (1974);<br></p>

<p>Applications can be used in the generation of carbenes, the amination of sulfenamides, and the preparation of lanthanide complexes.<br>References Hasan T.m et al.: Journal of the Chemical Society. Perkin Transactions 1 , 1923-1923, (1992); S C Bock Journal of the American Chemical Society 116, 7637-7637, (1994)<br></p>

<p>Applications 2-(4-Chlorophenyl)ethylamine has been used as a reactant in the preparation of isoalloxazine derivatives as cholinesterase inhibitors with a potential use in Alzheimer therapy.<br>References Kanhed, A.M., et. al.: Bioorg. Chem., 61, 7 (2015)<br></p>

<p>Applications Acetylacetonatobis(ethylene)rhodium(I) is a useful research chemical, a catalyst for the preparation and optical resolution of (tetramethyl)spirobiindane-diol and other useful research chemicals.<br>References Lee, A., et al.: J. Org. Chem., 81, 3520 (2016); Zhou, Q., et al.: Synthesis (2018); Jung, H., et al.: Adv. Synth. Catal., 359, 3160 (2017)<br></p>

<p>Applications 3-Methyl-1-(4-sulfophenyl)-2-pyrazolin-5-one acts as a reagent for the identification of sulfonic acids as efficient ecto-5'-nucleotidase inhibitors. Ecto-5'-nucleotidase inhibition is thought to provide an attractive approach to cancer therapy.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Iqbal, J., et al.: Eur. J. Med. Chem., 70, 685 (2013)<br></p>

<p>Applications Used in the preparation of Camptothecin derivatives, for their therapeutic use as antitumor agents.<br>References Wani, M.C., et al.: J. Med. Chem., 29, 2358 (1986), Miller, K.D., et al.: Invest. New Drugs, 22, 69 (2004), Punt, C.J.A., et al.: Eur. J. Cancer, 40, 1332 (2004), Wang, J.-Q., et al.: Bioorg. Med. Chem., 13, 549 (2005)<br></p>

<p>Stability Hygroscopic<br>Applications Aminomalononitrile p-toluenesulfonate is a reagent for diazonamide synthesis via heck endocyclization. It may also have implications for developing IκB Kinase-β inhibitors.<br>References Jeong, S., et al.: J. Org. Chem 63, 8640 (1998); Morwick, T. et al.: J. Med. Chem. 49, 2898<br></p>

<p>Applications 3-Bromo-2-methylbenzoic Acid is a disubstituted benzoic acid used in the preparation of various biologically active compounds such as α-2 adrenoceptor agonists, Smootherned receptor anatogonists and HIV-1 entry inhibitors.<br>References Stoilov, I. et al.: J. Hetercyc. Chem., 30, 1645 (1993); Katritzky, A. et al.: J. Med. Chem., 52, 7631 (2009); Pan, S. et al.: ACS Med. Chem. Lett., 1, 130 (2010);<br></p>

<p>Applications DI-TERT-BUTYLSILANE (cas# 30736-07-3) is a useful research chemical.<br></p>

<p>Applications Tetrakis(acetonitrile)copper(I) Hexafluorophosphate (cas# 64443-05-6) is a useful research chemical.<br></p>

<p>Applications (S)-(-)-α-Methylbenzylamine (cas# 2627-86-3) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 1,8-Dibromooctane is used as a reagent in the synthesis of novel 7-aminoalkyl-substituted flavonoid derivatives as potential cholinesterase inhibitors.<br>References Luo, W., et al.: Bioorg. Med. Chem., 24, 672 (2016)<br></p>

<p>Applications Bismuth Nitrate Pentahydrate acts as a precursor in the prepoaration of photocatalysts.<br>References Tang, J. et al.: J. Phys. Chem. C., 111, 12779 (2007);<br></p>

<p>Applications Dimethyl (2-Oxoheptyl)phosphonate is a useful synthetic intermediate, and is used as a reagent to synthesize Caffeic acid (C080000) derivatives, which function as 5-lipoxygenase, 12-lipoxygenase, and prostaglandin synthase inhibitors.<br>References Sugiura, M., et al.: Chem. Pharm. Bull., 37, 1039 (1989)<br></p>

<p>Applications Zinc Bromide is used as a catalyst in the synthesis of tetrazoles which exhibit antibacterial activity in vitro. Zinc Bromide is also a zinc salt that is added as a nutritional or functional ingredient in food and oral care products.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cui, J., et al.: Xiandai Shengwuyixue Jinzhan, 12, 3478 (2012); Keast, R.S.J.: J. Food Sci., 68, 1871 (2003)<br></p>

<p>Applications Phenylsilane is used as a stoichiometric reductant for direct reductive amination of aldehydes and ketones. It is also used as nerve cell growth substrates in its polymer form.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Apodaca, Richard., et al.: Org. Lett., 3(11), 1745-1748 (2001); Gikonyo, Barnabas K., et al.: Polym. Chem., 47(1), 222 (2006)<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-Methoxybenzyl Chloride is used as a reagent in the preparation of pyridone-conjugated monobactam antibiotics with gram-negative activity from Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brown, M F., et al.: J. Med. Chem., 5541 (2013); Cooper, M., et al.: Nature, 32, 472 (2011)<br></p>

<p>Applications (S)-(-)-Glycidol is a cyclic AB 2-type monomer that can be polymerized in a ring-opening multibranching polymerization. S)-(-)-Glycidol is also used as a starting reagent to synthesize non-peptidic HIV protease inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chiummiento, L., et al.: Tetrahedron, 65, 5984 (2009); Tokar, R., et al.: Macromolecules, 27, 320 (1994)<br></p>

<p>Applications Used in the preparation of hepatitis C virus (HCV) NS3 serine protease inhibitor.<br></p>

<p>Applications Dilithium Tetrachlorocuprate is an intermediate used in the synthesis of 10-Methylundecanol (M338110), an intermediate in the synthesis of Sulfobacin A;Also, it is derived from Lithium Chloride (L469105), which is primarily used in the synthesis of lithium metal by electrolysis. Also acts as a prescribed drug for bipolar mood disorder, it may also exhibit anti-inflammatory properties. Anti-cancer agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kamiyama, T., et al.: J. Antibiot., 48, 924 (1995), Gupta, P., et al.: Tetrahedron Lett., 45, 9641 (2004); Tsao, N. et al.: Antimicrob. Agents Chemother., 59, 1525 (2015); Cockle, J. et al.: 112, 693 (2015);<br></p>

<p>Applications 2,4-Dichlorobenzoyl Chloride is a reactant used in the synthesis of aroyl(sulfamoylphenyl)thiourea derivatives as 15-lipoxygenase inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mahdavi, M., et. al.: Eur. J. Med. Chem., 82, 308 (2014)<br></p>

<p>Applications Sodium Hydrosulfide Hydrate is a stable hydrogen sulfide (H2S) donor and oxidant in the formation of benzothiazoles. It is also used as a reagent in the synthesis of imidazo[1,2-b]thiazole derivatives as novel SIRT1 activators.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Meng, J., et al.: Int. J. Impot. Res., 25, 86 (2013); Park, N., et al.: Eur. J. Org. Chem., 2012, 1984 (2012); Vu, C.B., et al.: J. Med. Chem., 52, 1275 (2009)<br></p>

<p>Applications Sodium Nitrite is a common chemical reagent with pharmaceutical applications. It has been used in the treatment of cyanide poisoning however no longer in conjuction with sodium thiosulfate due to anumber of unwanted side effects. Also used in the inhibition of bacterial growth in cured and processed meats, prolonging shelf-life.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Baskin, S. et al.: J. Clin Pharm. et al.: 32, 368 (1992); Milkowski, A. et al.: Nitric Oxide, 15, 110 (2010);<br></p>

<p>Applications A structural homologue of the natural polyamine spermidine with antitumor activity that may make it useful as a antineoplastic agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Prakash, N. et al.: Anticancer Res., 8, 563 (1988); Sunkara, P.S. et al.: Adv. Exp. Med. Biol., 250, 707 (1988); Porter, C.W. et al.: Cancer. Res., 42, 4072 (1982);<br></p>

<p>Applications 3-Chloro-2,4-pentanedione is an useful building block reagent in the preparation of organic compounds of research interest that has been studied as a possible β-​diketone for antitumor treatment.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Nakano, K., et. al.: Anticancer Res., 24, 711 (2004);Lever, A. B. P.: Inorg. Chem., 29, 1271 (1990);Dawood, K., et. al.: Bioorg. Med. Chem., 14, 3672 (2006)<br></p>

<p>Applications 1,4-Cyclohexanedione Monoethylene Acetal is used in the preparation of series of potent analgesic compounds. 1,4-Cyclohexanedione Monoethylene Acetal is also used as a building block in the synthesis of tritium labelled probes for the autoradiography study of the dopamine reuptake complex.<br>References Linders, J. et al.: J. Lab. Comp. Radiopharm., 31, 671 (1992); Lednicer, D. et al.: J. Med. Chem., 22, 1157 (1979);<br></p>

<p>Applications Synthetic intermediate. Can be used in the synthesis of dialkylphenanthrenylamines.<br></p>

<p>Applications Sodium sulphate decahydrate (CAS# 7727-73-3) is a useful research chemical compound.<br></p>

<p>Applications Acetylenedicarboxylic Acid is used as an electrolyte in the fabrication of anodic nanoporous alumina. It is also used as a reagent in the synthesis of several organic compounds including that of derivatives of metronodazole (antibiotic and antiprotozoal medication) which display increased antimicrobial and antiparasitic properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kikuchi, T., et al.: Electrochem. Lett., 3, C25 (2014); Al-Masoudi, N., et al.: Monatsh. Chem., 147, 383 (2016);<br></p>

<p>Applications Bis(dibenzylideneacetone)palladium is a compound used as a component of a potentiometric membrane sensor to selectively determine the presence of thiocyanate in the urine of cigarette smokers. Bis(dibenzylideneacetone)palladium is also used as one of the homogeneous catalysts in the synthesis of Tricyclopentadiene from Dicyclopentadiene (D439350).<br>References Hassan, S., et al.: Electroanalysis, 18, 2070 (2006); Woo, J., et al.: Appl. Organomet. Chem., 28, 151 (2014)<br></p>

<p>Applications (R)​-​[2,​2'-​Bis(diphenylphosphin​o)​-​1,​1'-​binaphthyl]​dichlororuthenium is a catalyst used in the synthesis of helicobacter pylori lipopolysaccharide structures displaying anti-inflammatory activiy.<br>References Shimoyama, A. et al.: Chem. A Eur. J., 17, 14464 (2011);<br></p>

<p>Applications Dichlorophenylphosphine (cas# 644-97-3) is a useful research chemical.<br> E0<br></p>

<p>Applications Tetraethylammonium Tetrafluoroborate is used in the preparation of some organic salts of fluoboric acids.<br>References Wilke-D., et al.: Ber. Dtsch Chem. Ges.; 60B, 115 (1927)<br></p>

<p>Applications Mesitylcopper is an organometal used to synthesize compounds such as copper diketonate complexes.<br>References Larson, Alec. et al., Inorg. Chem. 59, 423-432(2020);<br></p>

<p>Applications Trimethyl Orthoformate is a reagent in the synthesis of CDK2/Cyclin A as antitumor agents derived from 3-aminopyrazole molecules. Also used in the preparation of PLD1/PLD2 selective inhibitors that decrease invasive migration of glioblastoma cells often associated with tumor progression.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pevarello, P. et al.: J. Med. Chem., 48, 2944 (2005); O'Reilly, M. et al.: J. Med. Chem., 56, 2695 (2013);<br></p>

<p>Applications Potassium Fluoride Dihydrate is a useful chemical reagent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Benzeneruthenium(II) Chloride Dimer is a catalyst for SNAr reactions of fluoroarenes and cyclic amines, a precatalyst for the hydrogenation of β-keto esters and a precursor for the preparation of other ruthenium catalysts.<br></p>

<p>Applications Chlorodifluoro-acetic Acid Sodium Salt (cas# 1895-39-2) is a compound useful in organic synthesis.<br></p>

<p>Applications Pyrrole-1-carboxylic Acid tert-Butyl Ester is an intermediate in the synthesis of pyrrole derived anti-cancer Agent.<br>References Ondachi, P.W., et al.: J. Med. Chem., 57, 836 (2014); You, H., et al.: Euro. J. Med. Chem., 46, 1153 (2011);<br></p>

<p>Applications n-Butyltriphenylphosphonium Bromide is used in the synthesis of inhibitors of tubulin polymerization thus expressing antimitotic and antitubulin properties. Also used in the synthesis of 3-phenylpropanoic acids as peroxisome proliferator-activated receptor dual agonists affecting the mitochondrial carnitine system.<br>References Cushman, M. et al.: J. Med. Chem., 38, 2041 (1995); Laghezza, A. et al.: J. Med. Chem., 56, 60 (2013);<br></p>

<p>Applications cis-1-Ethoxy-2-(tributylstannyl)ethene is used in the synthesis of (+)-pleuromutilin (P610500), an antibiotic substance produced by the basidiomycetes Pleurotus mutilus.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fazakerley, N.J., et. al.: Chem. Eur. J., 19, 6718 (2013)<br></p>

<p>Stability Moisture Sensitive<br>Applications Used in tests for skin corrosivity.<br> E0<br>References Fentem, J.H., et al.: Toxicology in Vitro, 12, 483 (1998),<br></p>

<p>Applications Diphenylphosphine oxide (cas# 4559-70-0) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-Nitrobenzyl Chloroformate is used in the preparation of prodrugs of cytotoxic acridines used in conjunction with enzyme prodrugs which counter carcinoma cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Asche, C. et al.: Bioorg. Med. Chem. Lett., 16, 1990 (2006); Hay, M. et al.: J. Med. Chem., 46, 2546 (2003);<br></p>

<p>Applications 1,1,1-Trimethoxybutane is used in the synthesis of angiotensin II receptor antagonists affecting blood pressure. Also used in the preparation of inhibitors of cyclin-dependant kinases.<br>References Yanagisawa, H. et al.: J. Med. Chem., 39, 323 (1996);<br></p>

<p>Applications Chloro(triethylphosphine)gold is an analogue of auranofin. Auranofin and its analogs show antimicrobial activity against multidrug-resistant pathogens<br>References Tizian M. et al.: Chem. Med. Chem. 13(22), 2448-2454 (2018)<br></p>

<p>Applications (S,S)-(+)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(ii) i sused as a catalyst for the hydrolytic kinetic resolution of terminal epoxides and the enantioselective ring opening of meso epoxides.<br>Chemical Name: (S,S)-(+)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminocobalt(ii) i sused as a catalyst for the hydrolytic kinetic resolution of terminal epoxides and the enantioselective ring opening of meso epoxides.<br></p>

<p>Applications Ethyl N-Boc-piperidine-4-carboxylate is used as a reagent to synthesize 3-amino-1-(5-indanyloxy)-2-propanol derivatives as sodium channel blockers to treat stroke patients. Ethyl N-Boc-piperidine-4-carboxylate is also used as a reagent to prepare inhibitors of tumour necrosis factor alpha-converting enzyme.<br>References Levin. J.: Heterocycles, 70, 691 (2006); Seki, M., et al.: Chem. Pharm. Bull., 60, 488 (2012)<br></p>

<p>Applications Ruthenium(IV) Oxide Hydrate is a coalescence inhibitor of hydrous RuO2 crystallites for capacitor electrodes preparation in hydrothermal process.<br>References Chang, K., et al.: Appl. Phys. Lett., 88, 193102 (2006)<br></p>

<p>Applications 3-Hexyn-1-ol is an unsaturated alcohol that, when subjected to stereoselective hydrogenation, produces cis-3-Hexen-1-ol (H295005), a compound that is important in the fragrance industry. 3-Hexyn-1-ol also exhibits antifungal properties against Aspergillus oryzae, a fungus that is used to produce fermented foods and beverages in Japan.<br>References Machida, M., et al.: Nature, 438, 1157 (2005); Sachse, A., et al.: Dalt. Trans., 42, 1378 (2013); Witte, P., et al.: Stud. Surf. Sci. Catal., 175, 135 (2010)<br></p>

<p>Applications 2-(2-Bromoethoxy)tetrahydro-2H-pyran, is an heterocyclic building block used in the synthesis of various chemical compounds.<br></p>

<p>Stability Hygroscopic<br>Applications Bismuth(III) chloride (cas# 7787-60-2) is a useful research chemical.<br></p>

<p>Applications Copper(I) Chloride, has many applications. The main use of copper(I) Chloride is as a precursor to the fungicide copper oxychloride. In organic synthesis, CuCl is used as an initiator of radical reactions such as the hydrostannation of α,β-unsaturated ketones.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wade, L. G., et al.: Org. Chem., 5th Ed., 871 (2003); Ooi, T., et al.: Tetrahedron Lett., 40, 2133 (1999);<br></p>