Alcoli

<p>Applications 2-Aminopropane-1,3-diol is used in the synthesis of novel potent inhibitors of human uridine phosphorylase used to reduce toxicity of 5-fluorouracil without affecting its antitumor activity.<br>References Renck, D. et al.: J. Med. Chem., 56, 8892 (2013);<br></p>

<p>Applications (2R)-2-(dimethylamino)propan-1-ol (cas# 55197-05-2) is a useful research chemical.<br></p>

<p>Applications 1-Adamantanebutan-4-ol is a building block used in various synthetic preparations. Adamantanealkanamines are potential antidepressant and anti-Parkinson agents.<br>References Chakrabarti, J., et al.: J. Med. Chem., 17, 602 (1974);<br></p>

<p>Applications 1-(3,5-Bis(benzyloxy)phenyl)pentan-2-ol is an intermediate for the synthesis of 2''-Hydroxycannabidiol (H824820), which is a metabolite of Canabidiol (C175300), a major constituents in marijuana. 2''-Hydroxycannabidiol can be used to investigate canabidiol metabolism and human liver microsomes that metabolize Canabidiol into 6α-Hydroxycannabidiol.<br>References Jiang, R., et al.: Life Sci. 89, 165 (2011); Lander, N., et al.: Science 169, 611 (1970)<br></p>

<p>Applications Androstenediol 17-Acetate is used in synthetic preparation for direct organocatalytic stereoselective transfer hydrogenation of conjugated olefins of steroids. Androstenediol 17-Acetate is also obtained from Dehydro Epiandrosterone (D229585) which is a major secretory steroidal product of the adrenal gland; secretion progresively declines with aging. May have estrogen-or androgen-like effects depending on the hormonal milieu. Intracellularly converted to androstenedione. It is used in treatment of menopausal syndrome.<br>References Ebeling, P., et al.: Lancet, 343, 1479 (1994); Morales, A.J., et al.: J. Clin. Endocrinol. Metab., 78, 1360 (1994); Ramachary, D.B., et al.: RSC Advances, 3, 13497-13506 (2013); Yahara, M., et al.: J. Toxicol. Sci., 2, 161 (1977);<br></p>

<p>Applications N-(2-Hydroxyethyl)tetracosanamide acts as a crude oil emulsifier.<br>References Zhiqiang, J., et al.: Fami Zhu Shen., 5 (2016)<br></p>

<p>Applications 3,7-Dimethyl-6-octen-1-yn-3-ol is a useful synthetic intermediate in the synthesis of Methylisopseudoionone (M314920); a derivative of Ionone (I731275) which is an aroma compound found in essential oils such as rose oil, and thus can be used in the perfumery industry.<br>References Susanne, B. et al.: J. Exp. Botany, 61, 2967 (2010); Hu, H. et al.: Arch. Pham. res., 32, 699 (2009)<br></p>

<p>Stability Unstable in aqueous media<br>Applications 1H-indazol-1-ylmethanol (cas# 1006-29-7) is a useful research chemical.<br></p>

<p>Stability Air Sensitive, Unstable in DMSO<br>Applications 2,2-DIMETHYL-2,3-DIHYDRO-1-BENZOFURAN-5-THIOL (cas# 1248920-72-0) is a useful research chemical.<br></p>

<p>Applications 2,5-Dimethoxybenzyl Alcohol can be used as a self-indicating standard for the determination of organolithium reagents<br>References Winkle, M.R. et al.: J. Chem. Soc. Chem. Comm., 3, 1980 (1980):<br></p>

<p>Applications 4-Pentyn-1-ol is an alkyne alcohol that is used as an initiator in ring-opening polymerization reactions. 4-Pentyn-1-ol is capable of undergoing cyclosisomerization, and is also used as a reactant in the synthesis of (+)-Serinolamide A, a cannabinoid CB1 receptor agonist.<br>References Gao, Y., et al.: Tetrahedron Lett., 54, 6511 (2013); Liao, R., et al.: Proc. Nat. Acad. Sci., 107, 22523 (2010); Miranda, P., et al.: Org. Lett., 5, 1979 (2003); Xu, N., et al.: Macromol. Chem. Phys., 208, 730 (2007)<br></p>

<p>Applications 1-(hydroxymethyl)cyclopentan-1-ol (cas# 74397-18-5) is a useful research chemical.<br></p>

<p>Applications (2S,3S,4R,5R)-2-(6-Amino-9H-purin-9-yl)-5-(((3-aminophenyl)thio)methyl)tetrahydrofuran-3,4-diol is an enantiomer of (2R,3R,4S,5S)-2-(6-Amino-9H-purin-9-yl)-5-(((3-aminophenyl)thio)methyl)tetrahydrofuran-3,4-diol (A577286), which an intermediate used in the synthesis of S-adenosylhomocysteine analogs with biological activities.<br>References Lawrence, F., et al.: Biochem. S-Adenosylmethionine Relat. Compd., Proc. Conf., 637 (1982); Shire, D., et al.: Nucleosides &amp; Nucleotides, 2, 21 (1983)<br></p>

<p>Applications 4-(2,4,4-trimethylpentan-2-yl)benzene-1,2-diol (cas# 1139-46-4) is a useful research chemical.<br></p>

<p>Applications 5-Propylbenzene-1,3-diol is an intermediate used to prepare Cannabigerovarin (C175140) which stimulates thermosensitive transient receptor potential (TRP) channels of vanilloid type-4 (TRPV4)-mediated [Ca2+]i with moderate-high efficacy (30-60% of the effect of ionomycin) and potency (EC50 0.9-6.4 μM),<br>References De Petrocellis, L., et al.: Acta Physiologica, 204, 255 (2012)<br></p>

<p>Applications (S)-3-Aminobutan-1-ol can be used as an intermediate in the preparation of compounds having HIV integrase inhibitory activity.<br>References Johns, B. et al.: J. Med. Chem., 56, 5901 (2013);<br></p>

<p>Applications 1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol is used as a reagent in the synthesis of P4-benzoxaborole-substituted macrocyclic inhibitors of HCV NS3 protease.<br>References Ding, C.Z., et al.: Bioorg. Med. Chem. Lett., 20, 7317 (2010)<br></p>

<p>Applications 3,5-Dimethoxybenzyl Alcohol is used in the synthesis of Resveratrol (R150000).<br></p>

<p>Applications O-Benzylmetaraminol is an impurity of M225565.<br></p>

<p>Applications 3-(1-(Ethylamino)cyclohexyl)phenol is a useful synthesis intermediate.<br></p>

<p>Applications 1,3,2-Dioxathiolane 2,2-Dioxide is an alkylating agent with carcinogenic activty.<br>References Van Duuren, B.L. et al.: J. Nat. Cancer Inst., 53, 695 (1974);<br></p>

<p>Applications 3,3-Dimethyl-2-butanol is used as a reagent in the synthesis of 2,4-dicarboxy-pyrroles as selective non-competitive mGluR1 antagonists. 3,3-Dimethyl-2-butanol is also used in the preparation of dihydropyrrole derivatives containing N-sulfanyl, sulfinyl, and sulfonyl moieties which have insecticidal activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ito, M., et al.: Bioorg. Med. Chem., 11, 489 (2003); Micheli, F., et al.: Bioorg. Med. Chem., 11, 171 (2003)<br></p>

<p>Applications 4-(tert-Butoxycarbonyloxy)benzylalcohol (cas# 156281-11-7) is a compound useful in organic synthesis.<br></p>

<p>Applications cis-3-Octen-1-ol (cas# 20125-84-2) is a useful research chemical.<br></p>

<p>Stability Acid Sensitive<br>Applications 2-tert-Butyldimethylsilyloxyethanol (cas# 102229-10-7) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Air Sensitive<br>Applications Thiol-PEG2-acid (cas# 1379649-73-6) is a useful research chemical.<br></p>

<p>Applications 4-Penten-2-ol is used in QSAR studies pertaining to toxicity levels of organic compounds in environmental situations.<br>References Bearden, A.P. et al.: Env. Toxicol. Chem., 16, 1311 (1997);<br></p>

<p>Applications 2-[(Tributylstannyl)methyl]-2-propen-1-ol is a useful reagent for organic synthesis.<br></p>

<p>Applications (1S)-1-(4-phenylphenyl)ethan-1-ol (cas# 150283-02-6) is a useful research chemical.<br></p>

<p>Applications trans-2-Butene-1,4-diol can be used as an extender in polyurethanes and as a catalyst precursor in the preparation of α,ω,kentro-telechelic poly(THF).<br>References Lin, I. Sioun, et al.: J. of Elastomers &amp; Plastics, 16(4), 265-80 (1984); Oike, Hideaki, et al.: Macromol., 33(23), 8898-8903 (2000)<br></p>

<p>Applications 2-Nonyn-1-ol is a Propargyl alcohol (P762550) derivative that is used as a reagent to synthesize Microcarpalide, a microfilament disrupting agent that is weakly cytotoxic to mammalian cells. 2-Nonyn-1-ol is also thought to have potential antifungal properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gershon, H., et al.: J. Pharm. Sci., 73, 1840 (1984); Ratnayake, A., et al.: Org. Lett., 3, 3479 (2001); Tamao, K., et al.: Tetrahedron Lett., 29, 6955 (1988)<br></p>

<p>Applications 5-Hexen-1-ol is a volatile organic compound that can be found in Brazilian chilli peppers (Capsicum spp.).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bogusz, S.Jr., et al.: Food Res. Int., 48, 98 (2012)<br></p>

<p>Applications Hydroxybutenolide can be used as reactant/reagent for synthetic preparation for enantioselective preparation of hydroxy-GR24 stereoisomers via contra-biomimetic nucleophilic cyclization.<br>References Morris, J. C., and McErlean, C. S. P.: Org. Biomol. Chem., 14, 1236-1238 (2016)<br></p>

<p>Applications Tetrahydro-2H-pyran-2-ol (cas# 694-54-2) is a useful research chemical.<br></p>

<p>Applications Glycerol is used both in sample preparation and gel formation for polyacrylamide gel electrophoresis. Glycerol (5-10%) increases the density of a sample so that the sample will layer at the bottom of a gel’s sample well. Glycerol is also used to aid in casting gradient gels and as a protein stabilizer and storage buffer component.<br>References Bartsch, W., et al.: Arzeim.-Forsch., 26, 1581 (1976)<br></p>

<p>Applications 1,4-Cyclohexanedimethanol diglycidyl ether (cas# 14228-73-0) is a useful research chemical.<br></p>

<p>Applications 1,2,5-Pentanetriol is used as a modifier in the preparation of polyoxymethylene having excellent impact resistance.<br>References Byun, Gyung S., et al.: PCT Int. Appl., WO 2018074781 A1 20180426 (2018)<br></p>

<p>Applications 3,5,5-Trimethyl-1-hexanol can be used as a fragrance material and a flavoring agent for food.<br>References McGinty, D., et al.: Food and Chem. Toxic., 48(Suppl. 4), S47-S50 (2010);Letizia, C. S., et al.: Food and Chem. Toxic., 38(Suppl. 3), S223-S225 (2000)<br></p>

<p>Applications 3-[benzyl(methyl)amino]propane-1,2-diol (cas# 60278-98-0) is a useful research chemical.<br></p>

<p>Applications Methanol-d is an isotope labelled version of Methanol (M276585). Methanol (M276585) is a common chemical reagent in organic synthesis participating in a variety of reactions. Methanol is a bioactive component with antimicrobial activities.<br>References Keskin, D., et al.: Fresenius Env. Bull.., 27, 7991 (2018)<br></p>

<p>Applications cis-4-Decen-1-ol is a reactant in the synthesis of epoxyisoprostanes as antiinflammatory agents.<br>References Egger, J., et. al.: Angew. Chem. Int. Edit., 52, 5382 (2013)<br></p>

<p>Applications M-PEG4-THIOL (cas# 52190-55-3) is a useful research chemical.<br></p>

<p>Applications 2-Tributyltin-allyl-1-ol (cas# 84666-30-8) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications (S,S)-2,3-Butanediol is the (S,S)-isomer of 2,3-Butanediol (B690020), a naturally occurring compound found in cocoa butter.<br>References Wang, Yu., et al.: J. Biological. Chem., 289, 6080 (2014); Cheng, C., et al.: J. Org. Chem., 78, 8562 (2013);<br></p>

<p>Applications 3-Furanmethanol (cas# 4412-91-3) is a useful research chemical.<br></p>

<p>Applications 2-Penten-4-yn-1-Ol is a useful reagent in the silver-​catalyzed cyclization of acetylenic alcohols. It is also employed in the studies related to the field of acetylenic epoxides.<br>References Pale, P., et al.: Eur. J. Org. Chem., 10109 (2000); Malinovskii, M. S., et al.: Tezisy Dokl. - Vses. Konf. Khim. Atsetilena, 5, 82 (1975)<br></p>

<p>Applications 2,4-Dimethyl-2-pentanol is used in the development of two reliable aqueous solubility models ASMS (aq. soly. based on mol. surface) and ASMS-​LOGP (aq. soly. based on mol. surface using calcd. log P (ClogP).<br>References Wang, J., et al.: J. Chem. Inf. Model., 47, 1395 (2007)<br></p>

<p>Applications 6-Amino-1-hexanol is used in the synthesis of guanidino analogs of roscovitine, which is a cyclin-dependant kinase. Also used in the preparation of tocotrienols which maintain anticancer, antiproliferative and antimigratory activity. Behery, F<br>References Doleckova, I. et al.: Eur. J. Med. Chem., 62, 443 (2013); Behery, F. et al.: Eur. J. Med. Chem., 59, 329 (2013);<br></p>

<p>Applications 4-Phenoxyphenol is a porous organic material with dumbbell channels that appear throughout its structure. These channels can also host solvent molecules during crystal growth. 4-Phenoxyphenol is also part of a group of phenolic compounds that have potential apoptotic activity, which can be used in the development of new treatments for cancer therapy.<br>References Hansch, C., et al.: Bioorg. Med. Chem., 11, 617 (2003); Thomas, L., et al.: Cryst. Growth. Des., 12, 1746 (2012)<br></p>

<p>Applications (1S)-1-(adamantan-1-yl)ethan-1-ol (cas# 138309-12-3) is a useful research chemical.<br></p>

<p>Applications 4-PROPOXYPHENOL (cas# 18979-50-5) is a useful research chemical.<br></p>

<p>Applications 1-(2H-1,3-benzodioxol-5-yl)prop-2-en-1-ol (cas# 5208-87-7) is a useful research chemical.<br></p>

<p>Applications 2-Thiopheneethanol is a thiophene derivative used in the preparation of oligothiophene isothiocyanates as fluorescent markers for biopolymers. 2-Thiopheneethanol is also used in the preparation of other biologically active compounds such as the analgesic Sulfentanyl and the antithrombotic Clopidogrel Hydrogen Sulfate (C587250).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Barbarella, G. et al.: J. Am. Chem. Soc., 123, 11600 (2001); Yang, Z.: Yiy. Gong., 16, 241 (1985); Lin, Z. et al.: Ship. Yu Yao., 12, 235 (2010):<br></p>

<p>Applications (3S,4R)-4-aminooxolan-3-ol (cas# 153610-14-1) is a useful research chemical.<br></p>