Alcoli

<p>2-Amino-9-fluorenol is a hydrophobic compound that binds to RNA. 2-Amino-9-fluorenol has been shown to have a binding constant of 1.2 x 10, which is much higher than the binding constant for curculigoside (5.2 x 10). This substance has shown to be an effective inhibitor of RNA synthesis in HL60 cells and various bacterial strains by binding to the ribose moiety of RNA and preventing transcription. The metabolic pathway for 2-amino-9-fluorenol consists of two steps: one involving a reactive intermediate, potassium ion, and another with methylamine as the reactant. These reactions are catalyzed by enzymes such as acetaldehyde dehydrogenase and amino transferases, respectively.</p>

<p>3-(1,1,2,2-Tetrafluoroethoxy)phenol is a versatile building block that can be used in the synthesis of complex compounds. It is also a reagent and speciality chemical and has CAS No. 53997-99-2. 3-(1,1,2,2-Tetrafluoroethoxy)phenol is a useful building block for organic synthesis and has been used as a reaction component or scaffold.</p>

<p>Deoxynivalenol is a mycotoxin that is produced by the fungi Fusarium graminearum and F. culmorum. It produces toxic effects in humans and animals, including human immunoglobulin E (IgE) production, acute toxicities, and cytotoxic effects on cultured human leukocytes. The analytical method for deoxynivalenol detection includes a variety of in vitro methods such as enzyme-linked immunosorbent assays (ELISA), competitive ELISA, fluorescent antibody staining assay, fluorescence polarization immunoassay (FPIA), competitive FPIA, and high performance liquid chromatography (HPLC). Deoxynivalenol binds to dna with high affinity and has been shown to have fusarial activity. The toxicity of deoxynivalenol can be confirmed by the mitochondrial membrane potential assay or by the assessment of vomitoxin levels. Colloidal gold can be used for identification of deox</p>

<p>Intermediate in the synthesis of empagliflozin</p>

<p>1,6-Hexanediol dimethacrylate - stabilized with MEHQ is a reactive chemical that is used to generate light-sensitive particles. The light exposure of these particles causes them to react and form new bonds, which can be exploited for various applications. 1,6-Hexanediol dimethacrylate - stabilized with MEHQ has been shown to cause genotoxic effects in primary cells and cell nuclei, as well as radiation-induced DNA damage in human fibroblast cells. It has also been shown to interfere with the replication of DNA in human cancer cells. This agent is chemically similar to other known carcinogens such as allyl carbonate and benzene.</p>

<p>Stable under physiological and chemical conditions, 1-Boc-azetidine-3-yl-methanol is a linker that forms permanent bonds in conjugates, particularly in antibody-drug conjugates (ADCs) and as a linker in PROTAC (PROteolysis TArgeting Chimera) molecules for targeted protein degradation. It is also a versatile chemical intermediate used to synthesize complex organic molecules, particularly in pharmaceuticals, agrochemicals, and research chemicals.</p>

<p>3-Aminoquinoline is a chemical compound that inhibits the activity of the epidermal growth factor receptor (EGFR). It is a potent inhibitor of cell proliferation and has been shown to have antitumour activity. 3-Aminoquinoline has been shown to inhibit the proliferation of carcinoma cell lines. This drug binds to the EGFR receptor, preventing it from activating downstream signalling pathways that control cell growth. 3-Aminoquinoline also has biological properties, including matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, analytical chemistry, sample preparation, and Suzuki coupling reaction. The molecule is structurally analyzed using chemical structures and structural analysis techniques such as thermodynamic data or proton NMR spectroscopy. 3-Aminoquinoline also interacts with sugars through hydrogen bonding and oligosaccharides. These interactions are found to be high in value in some cases.</p>

<p>Please enquire for more information about 4-phenyl-5-(4-(benzyloxy)phenyl)-1,2,4-triazole-3-thiol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Diacetoxyscirpenol is a mycotoxin that is found in wastewater and has been shown to have the ability to inhibit certain enzyme activities. It is a glucuronide conjugate that is excreted by humans, and can be detected in urine samples. The metabolite of Diacetoxyscirpenol, 4-hydroxy-2,3-dihydroxymethyl-5-(2H)-furanone (4OH-DMF), has been shown to induce antibody response in mice. The LC-MS/MS method for detecting Diacetoxyscirpenol uses a monoclonal antibody that recognizes the toxin. This antibody binds to the toxin and activates an enzyme cascade that leads to the production of a fluorescent dye. The intensity of fluorescence can be quantified using fluorometry or spectrophotometry. /nowiki&gt;/pre&gt;</p>

<p>Please enquire for more information about 1-(2-Methyl(8-quinolyloxy))-2-nitro-4-(trifluoromethyl)benzene including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4,5-Diphenyl-4H-1,2,4-triazole-3-thiol is a thione that has potent antibacterial activity against Gram positive bacteria. It is also used as a building block in the synthesis of polymers for medical use and other applications. 4,5-Diphenyl-4H-1,2,4-triazole-3-thiol has been shown to be photostable in the presence of oxygen. It is not active against Gram negative bacteria and does not show any effect on coccidiosis or cancer. 4,5-Diphenyl-4H-1,2,4-triazole-3-thiol has been shown to have a potent inhibitory effect on human adenocarcinoma cells (A549) at concentrations of 0.25 mM and higher.</p>

<p>Please enquire for more information about 4-(2-methyl(8-quinolyloxy))-1-nitrobenzene including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-Chloro-1-(6-methyl(1,2,3,4-tetrahydroquinolyl))propan-1-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Amino(6-methyl(1,2,3,4-tetrahydroquinol-1-yl))methane-1-thione including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 5-(3-Chlorophenyl)-4-phenyl-4H-1,2,4-triazole-3-thiol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-Nitro-1-(8-quinolyloxy)-4-(trifluoromethyl)benzene including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 5-(Benzimidazol-2-ylthiomethyl)-4-phenyl-1,2,4-triazole-3-thiol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 4-oxo-7-(benzyloxy)hydroquinoline-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about ((4-Chlorophenyl)sulfonyl)-8-quinolylamine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-[(3-Phenoxyphenyl)methylene]-2H-1,4-benzothiazin-3(4H)-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Amino-1,2,3,4-tetrahydroquinol-1-ylmethane-1-thione including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-(4-Bromophenyl)-5-(hydroxyimino)-7,7-dimethyl-6,7,8-trihydrocinnoline including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Poly(bisphenol-A-co-epichlorohydrin) is an epoxy polymer that reacts with a fatty acid to form a cationic polymer. It has a high resistance to thermal expansion and inorganic acids, making it a good sealant. In addition, poly(bisphenol-A-co-epichlorohydrin) is insoluble and not reactive, which makes it resistant to structural analysis. Poly(bisphenol-A-co-epichlorohydrin)'s thermal stability also makes it suitable for use as a boron nitride coating on zirconium oxide.</p>

<p>Please enquire for more information about 4-(4-((3-(trifluoromethyl)phenyl)amino)-3,5-thiazolyl)benzene-1,2-diol, hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-Chloro-2-(2-methyl(8-quinolyloxy))-5-(trifluoromethyl)pyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>16alpha,17alpha-Epoxypregnenolone is a synthetic insect odorant that binds to the odorant binding protein (OBP) and has been used in research to investigate the relationship between odorant binding and olfaction. The OBPs are thought to play an important role in the detection of odors by binding to specific odorants, which then initiate a sensory response. 16alpha,17alpha-Epoxypregnenolone has also been shown to bind with recombinant OBP and have fluorescence properties, making it useful for biosensors. This compound may be useful as an experimental or research tool for investigating olfactory receptors in insects or other organisms.</p>

<p>Please enquire for more information about 4-(5-Phenyl-4-thioxo-2,3,5-triazolinyl)phenol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 5-(indol-3-ylmethyl)-4-(2-methylphenyl)-1,2,4-triazole-3-thiol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-Phenyl-5-(2-thienyl)-4H-1,2,4-triazole-3-thiol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-Indol-3-yl-2-oxo-N-(8-quinolyl)ethanamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about ((8-Quinolylamino)methylene)methane-1,1-dicarbonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 3-((4-Methoxyphenyl)methylene)-1,4-dihydro-4-thiaquinolin-2-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Applications Cyclopentaneethanol is used in the prepartion of phenylalanine derivatives for incorporation into peptides as CD4 mimetic miniproteins interacting with HIV-1 surface glycoprotein. It is also used in the preparation of tertiary amine muscarinic receptor antagonists applied towards the treatment of chronic obstructive pulmonary disease.<br>References Morellato-Castillo, L. et al.: J. Med. Chem., 56, 5033 (2013); Glossop, P. et al.: J. Med. Chem., 54, 6888 (2011);<br></p>

<p>Applications 2-(6-Aminopurin-9-yl)ethanol is a useful intermediate in the preparation of aryloxyalkyl derivatives of adenine with antiviral activity.<br>References Petrov, V. I., et al.: Chemistry of Heterocyclic Compounds, 39, 1218 (2003)<br></p>

<p>Applications 5-Propylbenzene-1,3-diol is an intermediate used to prepare Cannabigerovarin (C175140) which stimulates thermosensitive transient receptor potential (TRP) channels of vanilloid type-4 (TRPV4)-mediated [Ca2+]i with moderate-high efficacy (30-60% of the effect of ionomycin) and potency (EC50 0.9-6.4 μM),<br>References De Petrocellis, L., et al.: Acta Physiologica, 204, 255 (2012)<br></p>

<p>Applications 10-Undecen-1-ol (cas# 112-43-6) is a useful research chemical.<br></p>

<p>Applications 3,3-DIPHENYLPROPANOL (cas# 20017-67-8) is a useful research chemical.<br></p>

<p>Applications Tetrahydro-4-pyranol is a building block of various organic compounds and pharmaceuticals.<br>References Chan, A.W., et al.: J. Med. Chem., 53, 3086 (2010); Desjardins, A.E.. et al.: Phytochem., 27, 767 (1988);<br></p>

<p>Applications 2-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)amino]ethanethiol is used in the preparation of fluorescent N/S acyl derivatives.<br>References 2-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)thio]ethanamine<br></p>

<p>Applications (S)-Pyroglutaminol (cas# 17342-08-4) is a compound useful in organic synthesis.<br></p>

<p>Applications 4,4-dimethylpentan-2-ol (cas# 6144-93-0) is a useful research chemical.<br></p>

<p>Applications 3,4-Diaminophenol (cas# 615-72-5) is a useful research chemical.<br></p>

<p>Applications (1R,2R)-rel-trans-1,2-Cyclopentanediol is a building block for the synthesis of chiral phosphine ligands. It can also be used to prepare benzoquinolines and benzoindoles via heterocyclization of naphthylamines with diols catalyzed by iridium chloride/BINAP<br>References Kündig, E., et al.: Helv. Chim. Acta, 77, 421 (1994); Aramoto, H., et al.: J. Org. Chem., 74, 628 (2009)<br></p>

<p>Applications 2-Mercapto-4,6-di-tert-butylphenol (cas# 53551-74-9) is a compound useful in organic synthesis.<br></p>

<p>Applications (1R)-2-(methylamino)-1-phenylethan-1-ol (cas# 495-42-1) is a useful research chemical.<br></p>

<p>Applications Thietan-3-ol (cas# 10304-16-2) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications Used in the production of antimicrobial agents.<br>References Selvin, J. et al.: App. Microbio. Biotech., 83, 439 (2009);<br></p>

<p>Applications 1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol is used as a reagent in the synthesis of P4-benzoxaborole-substituted macrocyclic inhibitors of HCV NS3 protease.<br>References Ding, C.Z., et al.: Bioorg. Med. Chem. Lett., 20, 7317 (2010)<br></p>

<p>Applications (S,S)-2,3-Butanediol is the (S,S)-isomer of 2,3-Butanediol (B690020), a naturally occurring compound found in cocoa butter.<br>References Wang, Yu., et al.: J. Biological. Chem., 289, 6080 (2014); Cheng, C., et al.: J. Org. Chem., 78, 8562 (2013);<br></p>

<p>Applications 4,4'-Thiobisbenzenethiol acts as a reducing agent, and affects the catalytic activity of caspase-3 protein.<br>References Okun, I. et al.: J. Biomol. Screen., 11, 694 (2006);<br></p>

<p>Applications Tert-butyl Alcohol is used as an organic solvent. It is also used in the synthesis of proteosome inhibitors that are quite potent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kawamura, S. et al.: J. Med. Chem., 56, 3689 (2013); Galy, N. et al.: Tetrahedron Lett., 54, 2703 (2013)<br></p>

<p>Applications 3,3-Diethoxy-1-propanol is used as a reactant in the synthesis of nanoparticles.<br>References Sumitani, Shogo, et al.: Reactive &amp; Func. Polymers, 71(7), 684-693 (2011);Kanakubo, Yurie, et al.: Colloids and Surfaces, B, 78(1), 85-91 (2010)<br></p>

<p>Applications 2-(1,1-Dimethylethoxy)-1-propanol is a useful reagent for organic synthesis.<br></p>

<p>Applications 5-Amino-2-chloro-4-fluorophenol is a reagent involved in the design and structure of potent vascular endothelial growth factor (VEGF) receptor tyrosine kinase inhibitors.<br>References Hennequin, L. F., et al.: J. Med. Chem., 42, 5369-5389 (1999);<br></p>

<p>Applications 3-[(Dimethylamino)carbonyl]phenol can be used in the synthesis of novel purine and bicyclic pyrimidine, which are factor Xa inhibitors, and also have high selectivity over thrombin and trypsin.<br>References Buckman B. O., et al.: Bio. Med. Chem. Let., 8, 2235 (1998)<br></p>

<p>Applications 1,3-Bis(2-acetylphenoxy)-2-propanol is a useful research intermediate.<br>References Sangwan, N. K., et al.: Indian J. Chem. B. Org. Chem. Incl. Med. Chem. ,31B, 590 (1992)<br></p>

<p>Applications 1,3-Diamino-2-propanol is a reagent used in the quantitative fluorescent detection of pyrophosphate with quinolin-ligated dinuclear zinc complexes.<br>References Mikata, Y., et al.: Inorg. Chem., 52, 10223 (2013)<br></p>

<p>Applications 1,3,2-Dioxathiolane 2,2-Dioxide is an alkylating agent with carcinogenic activty.<br>References Van Duuren, B.L. et al.: J. Nat. Cancer Inst., 53, 695 (1974);<br></p>

<p>Applications O-Benzylmetaraminol is an impurity of M225565.<br></p>

<p>Applications Used in the preparation of pyridine analogues of vitamin B1.<br>References Tracy, A. &amp; Elderfield, R.; J. Org. Chem., 6, 54 (1941); Tracy, A. &amp; Elderfield, R.; Science, 92, 180 (1940)<br></p>

<p>Applications The toxicity of 4-Butoxybenzyl Alcohol has been studied on rapidly dividing cancer cells (L1210 leukemia).<br>References Kapur, S., et. al.: Chemosphere, 41, 1643 (2000)<br></p>

<p>Stability Light Sensitive<br>Applications cis-1,5-Octadien-3-ol is an intermediate in the synthesis of (Z)-Octa-1,5-dien-3-one (O235830), which is an odorant found in green tea, and palm wines.<br>References Katsuno, T., et. al.: Food Chem., 148, 388 (2014); Lasekan, O.: Molecules, 18, 11809 (2013)<br></p>

<p>Applications 1-Butanol is a common chemical reagent used in biodiesel production. Also it has been used in the study the polarization of vapor-deposited 1-butanol films (1) as well as in the preparation of bioavailable CB1 antagonists (2) . Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Gavra, I. et al.: J. Chem. Phys. 2017 Mar 14;146(10):104701.2. Röver, S. et al.: J. Med. Chem. 2013 Dec 27;56(24):9874-96.<br></p>

<p>Applications 1-Adamantanemethanol is used as a reagent in the synthesis of adamantane and noradamantane based histone deacetylase (HDAC) inhibitors for the treatment of cancer. It is also used as a reagent in the synthesis of (1-adamantyl)methyl glycidyl ether, a versatile building block for living polymerization.<br>References Gopalan, B., et al.: Bioorg. Med. Chem. Lett., 23, 2532 (2013); Suzuki, T., et al.: J. Med. Chem., 55, 9562 (2012); Moers, C., et al.: Macromol. Rapid Comm., 35, 1075 (2014)<br></p>

<p>Applications 1,3-Propanedithiol is a dithiol that is a useful reagent in synthetic preparations. It is widely used for protection of carbonyl containing compounds. 1,3-Propanedithiol is also used in the synthesis of aminoalkynyldithianes calcium channel blockers.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Evans, D., et al.: J. Am. Chem. Soc., 99, 5009 (1977); Kamitori, Y., et al.: J. Org. Chem., 51, 1427 (1986); Adams, T., et al.: J. Med. Chem., 34, 1585 (1991); De, S. K.: Tetrahedron Lett., 45, 2339 (2004);<br></p>

<p>Applications 2-Aminopropane-1,3-diol is used in the synthesis of novel potent inhibitors of human uridine phosphorylase used to reduce toxicity of 5-fluorouracil without affecting its antitumor activity.<br>References Renck, D. et al.: J. Med. Chem., 56, 8892 (2013);<br></p>

<p>Applications 2,3,5-Trimethylphenol is a reagent used in the synthesis of antibiotics. Also used in the preparation of vitamin E synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Velema, W. et al.: Nat. Chem., 5, 924 (2013); Carril, M. et al.: J. Catal., 283, 55 (2011);<br></p>

<p>Stability Hygroscopic<br>Applications 5-(4-aminophenyl)-1,3,4-oxadiazol-2-ol (cas# 113118-47-1) is a useful research chemical.<br></p>

<p>Applications Mevinolinic Acid, Monoammonium Salt can be used as reactant/reagent in process for the preparation of the Simvastatin precursor, 2,2-dimethylbutanoic acid (1S,3R,7S,8S,8aR)-8-[(3R,5R)-7-(cyclopropylamino)-3,5-dihydroxy-7-oxoheptyl]-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-1-naphthalenyl ester, via an amidation reaction.<br>References Khanna, J., et al.: Indian, IN 184809 A1 20000930 (2000)<br></p>

<p>Stability Acid Sensitive<br>Applications 2-tert-Butyldimethylsilyloxyethanol (cas# 102229-10-7) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3,​7-​Dimethyl-​1-​octanol is a useful organic reactant/reagent.<br>References Dantignana, V., et al.: ACS Cent Sci., 3, 1350-58 (2017); Jana, S., et al.: Org, Lett., 19, 746-49 (2017);<br></p>

<p>Applications 23-Azido-3,6,9,12,15,18,21-Heptaoxatricosan-1-ol is used in the synthesis of heterobifunctionalized oligo(ethylene glycol) linkers for use in drug delivery.<br>References Goswami, L. et al.: Org. Biomol. Chem., 11, 1116 (2013);<br></p>