Ammine

(N,N-Dimethyl)methyleneammonium iodide is a potent antagonist for the histamine H2 receptor that has been shown to inhibit gastric acid secretion. It is an enantiopure compound that can be prepared by asymmetric synthesis using palladium complexes. The methylene group in this molecule is activated with hydroxylamine and acrylates, which are then reacted with ethyl diazoacetate and amines to produce (N,N-dimethyl)methyleneammonium iodide. (N,N-Dimethyl)methyleneammonium iodide is a potent antagonist at the histamine H2 receptor, where it can inhibit gastric acid secretion and reduce stomach ulcers. It also has been shown to have anti-inflammatory effects.

O,O'-Bis(3-aminopropyl)polyethylene glycol is a PEG polymer categorised as homobifunctional PEG (X-PEG X). Used as a linker, O,O'-bis(3-aminopropyl)polyethylene glycol is used to attached PEG to proteins, peptides, oligonucleotides, nanoparticles and small molecules via pegylation, a bioconjugation technique.

Diisopropylammonium dichloroacetate (DADCA) is a chemical that inhibits the metabolism of glucose. It has been shown to have a hypoglycemic effect in rats and is being investigated as a treatment for metabolic disorders such as diabetes and obesity. DADCA has also been shown to reduce liver lesions in animals with chronic viral hepatitis, and has been found to be effective in reducing tumor growth in mice. This drug can also be used to treat bowel disease by reducing the amount of ammonia released by bacteria. DADCA may also have physiological effects on humans, including an increase in blood pressure and fever, although these effects have not yet been studied.

4-(Methylnitrosoamino)-1-(3-pyridinyl)-1-butanone (NNK) is a carcinogenic chemical that has been identified in tobacco smoke. It induces squamous cell carcinomas in the respiratory tract of rodents and induces lung cancer in the offspring of pregnant rats exposed to NNK. This compound binds to double-stranded DNA, with high affinity for the minor groove, and inhibits DNA synthesis by binding to enzymes such as polymerase chain. In addition, it has been shown to cause transformation of epithelial cells into mesenchymal cells in vitro. 4-(Methylnitrosoamino)-1-(3-pyridinyl)-1-butanone binds to α7 nicotinic acetylcholine receptors and increases the response element activity.

2-Amino-5,6-dichlorobenzothiazole is an aminobenzothiazole derivative that has been shown to have antibacterial activity. It is a hydrophobic molecule with a skeleton consisting of alternating amines and carboxylic acids. 2-Amino-5,6-dichlorobenzothiazole binds to the fatty acid ester component of bacterial cell walls by hydrogen bonding or ionic interactions, disrupting the integrity of the cell wall and inhibiting the growth of bacteria. 2-Amino-5,6-dichlorobenzothiazole can be used to decolorize dyes and textiles that have been stained by oily materials. It is also used as a surfactant in personal care products such as shampoos and conditioners.

Lycopsamine N-oxide is a pyrrolizidine alkaloid derivative, which is a naturally occurring compound found in certain plant species, particularly within the Boraginaceae family. This compound is typically produced as a secondary metabolite in these plants. Its mode of action involves metabolic activation in the liver, where enzymes convert it into reactive intermediates capable of binding to cellular macromolecules, ultimately leading to toxic effects.

tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate is an organic compound that can be synthesized by the reduction of 5-bromo-2-nitro pyridine with a palladium catalyst. It has been shown to inhibit the growth of cancer cells in vitro and in vivo, and is being investigated as a potential treatment for breast cancer.

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3,5-Diamino-2,4,6-trimethylbenzenesulfonic acid (DTMS) is an aromatic hydrocarbon that has been found in the environment. DTMS is used as a chlorine scavenger in water treatment plants and wastewater treatment facilities to remove chlorinated organics from the water. It has been shown to be a ligand for uranium. DTMS reacts with cyanuric acid to form 3,5-dichloro-2,4,6-trimethylbenzenesulfonyl chloride (CAS No. 52834-57-1). DTMS also exhibits affinity for metal ions such as copper and nickel.