Amidi

3-Amino-4-methylbenzamide is an interchemical that can be utilized to synthesize naphthol. 3-Amino-4-methylbenzamide is an amide that has been shown to have a molecular modeling structure of a conformation. The interaction of 3-amino-4-methylbenzamide with the P38 kinase enzyme has been shown to inhibit the activity of this enzyme, which may lead to its use as a drug for the treatment of inflammation.

2,3-Diaminobenzamide is a synthetic aromatic compound that is used as a radiation stabilizer. It is also an effective antimicrobial agent with reactive properties against bacteria and fungi. 2,3-Diaminobenzamide has been shown to have anti-cancer properties and can be used to treat inflammatory diseases such as rheumatoid arthritis or ulcerative colitis. The intramolecular hydrogen bond between the amide group and the benzene ring in 2,3-diaminobenzamide contributes to its stability and biological activity.

Malonamide is a natural product with biological properties that include anti-inflammatory activity. It is a receptor antagonist that binds to the nicotinic acetylcholine receptors and blocks the binding of acetylcholine, thereby inhibiting muscle contraction. Malonamide has been shown to have good chemical stability and phosphorus pentoxide tolerance. This compound also has high steric interactions with halogens, which allows it to act as an effective antiseptic agent for wounds or skin infections caused by bacteria such as Staphylococcus aureus or Pseudomonas aeruginosa. Malonamide has been shown to be active against both Gram-positive and Gram-negative bacteria, including methicillin resistant strains. Malonamide binds to copper ions and forms an intramolecular hydrogen bond with the nitrogen atoms in the molecule. This interaction stabilizes its conformation and leads to increased chemical stability in comparison with other nitrogen containing drugs.

5-(Acetylamino)-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide is a reactive iodinated contrast agent that is used in the diagnostic imaging of body cavities and blood vessels. It can be prepared by the acetylation of 5-(acetylamino)naphthalene-2,3-diol with 2,4,6-triiodobenzene dicarboxylic acid using an alkali metal as a base. The yields for this reaction are dependent on the type of solvent used. This chemical has two functional groups: an amide and an acetate group. It reacts with iohexol to form a radiocontrast product that contains both iodine and propanediol. This process is industrially carried out by mixing 5-(acetylamino)naphthalene-2,

Hydroxy tolbutamide is a drug with an unknown mechanism of action. It has been shown to inhibit the transcription-polymerase chain reaction and human serum in vitro. This drug may be used as a marker for renal disease, as it has been shown to increase the level of magnesium in urine and reduce the rate of protein synthesis in rat liver microsomes. Hydroxy tolbutamide also inhibits receptor activity, which may be due to its ability to inhibit the metabolic rate.

2-Chloro-5-nitrobenzene sulfonamide (2CNS) is a glycol ether that has been shown to inhibit the activity of carbonic anhydrase. It has been shown to be a competitive inhibitor of the enzyme, and can be used as a lead compound for developing new drugs. 2CNS has been shown to inhibit an anhydrase that is found in bacteria, such as Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus. This inhibition causes increased levels of hydrogen ions in the bacterial environment, which leads to the acidification of their surroundings. 2CNS also inhibits chloride ion uptake in these bacteria.
2CNS's pharmacophore includes two aromatic hydrocarbon rings with at least one hydrogen bond acceptor group on each ring. This pharmacophore is responsible for its inhibition of carbonic anhydrase and chloride ion binding site.

Solid phase peptide anchor; tool for the Fmoc solid phase synthesis of peptide amides.
100-200 mesh. 1% DVB, substitution range 0.3-0.6 meq/g