Amidi

Ethionamide is a drug that is used for the treatment of tuberculosis. It binds to the enzyme preparations in the bacterial cell wall by competitive inhibition, which prevents formation of an antibiotic-inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. The sulfoxide form of ethionamide is converted to the sulfone form when it enters the body. This conversion takes place primarily in the liver with assistance from alcohol dehydrogenase, cytochrome P450, and glutathione reductase. The sulfone form has higher potency than its precursor (sulfoxide) because it has lower protein binding affinity and more rapid elimination from plasma.

<p>Dimethylphosphonoacetamide (DMPPA) is a phosphorus-containing compound that is used as an intermediate in the synthesis of fatty acids. DMPPA can be synthesized by the reaction of ethylene diamine and phosphorus pentoxide, which is a common reagent for preparing phosphorus compounds. The reaction mechanism has been studied using electrochemical impedance spectroscopy. This study revealed that DMPPA can be converted to a water-soluble product by treatment with water vapor or by adding cotton. In addition, the kinetic data obtained from this study showed that the reaction rate was affected by temperature and the type of solvent used. The frequency shift observed during this study indicated that nitrogen atoms are involved in the reaction mechanism.</p>

4-(Chloromethyl)benzamide is a potent inhibitor of cyclohexane ring formation in proteins and has been shown to be effective against bacteria, fungi, and parasites. 4-(Chloromethyl)benzamide inhibits the synthesis of proteins by targeting the active site of piperazine synthase, an enzyme involved in the production of piperazine. The carbon nanotube linker is a novel molecule that can be used for the attachment of the 4-(chloromethyl)benzamide molecule to cetirizine. In addition, 4-(chloromethyl)benzamide has been shown to have an effective dose at 0.1 μM and a half-life time of 2 hours in rats.

<p>Non-steroidal androgen receptor antagonist</p>

<p>N-(3-Hydroxypropyl)trifluoroacetamide is an alkaline hydrolysis product of 3-hydroxypropyl trifluoroacetate. It is a primary amino compound that can be used as an intermediate in the production of vinyl ethers and acetals. This chemical is used for the synthesis of vinyl acetals, which are important intermediates in the manufacturing of polymers.</p>

<p>2-Piperazin-1-ylacetamide hydrochloride is a drug that binds to the protein PCSK9, which transports cholesterol into cells. It blocks the transport of cholesterol and therefore lowers the level of cholesterol in blood. 2-Piperazin-1-ylacetamide hydrochloride is used for the treatment of bowel disease, atrial fibrillation (a type of irregular heartbeat), congestive heart failure, and as an anti-viral agent. This drug has been shown to reduce levels of LDL cholesterol by up to 60%. 2-Piperazin-1-ylacetamide hydrochloride has also been shown to be effective against cancers such as prostate cancer and inflammatory bowel disease.</p>

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<p>Morpholine-4-carboxamide is a polymerase chain inhibitor that inhibits the activity of DNA polymerases. It binds to the DNA template strand and prevents the enzyme from adding nucleotides to the primer strand, thereby inhibiting DNA synthesis. Morpholine-4-carboxamide has shown efficacy in treating hyperproliferative diseases such as cancer cells and psoriasis. This drug has been shown to inhibit caspase activation and histone protein acetylation, which may be related to its anti-cancer properties. Morpholine-4-carboxamide also binds to cannabinoid receptor 2 (CB2) and may have therapeutic effects on inflammatory diseases such as psoriasis and arthritis.</p>

<p>4-Amino-2,5-diethoxyphenyl)benzamide is a small molecule that inhibits the enzyme activity of polymerase chain reaction (PCR), DNA topoisomerase I, and DNA gyrase. It has been shown to inhibit the growth of human leukemia cells in culture. 4-Amino-2,5-diethoxyphenyl)benzamide also inhibits rat liver microsomes and can be used for the treatment of neurodegenerative diseases.</p>

<p>Dimethylmorpholine-4-carboxamide (DMMC) is an unsymmetrical, synthetic carbamate that has antiviral properties. The antiviral properties of DMMC are due to its ability to inhibit the synthesis of viral proteins by binding to a site on the enzyme RNA polymerase and blocking the formation of a functional enzyme. This agent also has been shown to inhibit the production of nitric oxide in k562 cells. DMMC is marketed for use as an insecticide, but it has not been approved for this use. In crystallography studies, DMMC was found to have high yield and low melting point.</p>

1-Methyl-1,4-dihydronicotinamide (1MDNA) is a flavine adenine dinucleotide analog that has been shown to be a potent inhibitor of the enzyme catalase. 1MDNA binds to the active site of the enzyme and prevents hydrogen peroxide from being converted into water and oxygen. This inhibition slows down or stops the reaction, which leads to reduced production of reactive oxygen species. 1MDNA inhibits other enzymes in a similar manner, including transferases and kinases. The kinetic properties of 1MDNA have been studied by performing kinetic studies on model systems at different temperatures. X-ray crystal structures have also been obtained for 1MDNA bound to catalase and ferredoxin.

<p>L-Alaninamide is a protonated amino acid that reacts with the bacterial cell membrane and causes it to rupture. L-Alaninamide is synthesized by hydrolysis of the ester bond between butyric acid and serine protease in the presence of immobilized d-alanine. The reaction is carried out at a pH of 5.5, and the release of pressor is observed. This reaction takes place in an aqueous solution containing fatty acids as solvents. The type strain of this amino acid is E. coli.</p>

N-Benzylbenzamide is a molecule that contains an amide group, which is considered to be a hydrogen bond acceptor. The amine group of this compound can also act as a hydrogen bond donor. It has been shown to inhibit the activity of tyrosinase, which is an enzyme responsible for the production of melanin in melanocytes. N-Benzylbenzamide has been shown to have a molecular mechanism similar to that of hydroquinone and other phenolic compounds. In addition, it has been found to decrease microvessel density and inhibit the growth of cancer cells in vitro. This compound is not yet approved for use as a drug but may be used in future research studies as an alternative treatment for cancer.

<p>1-Benzyl-1,4-dihydronicotinamide is a drug that has been shown to have potential in treating metabolic disorders by restoring the balance of nitrogen atoms. It has been shown to be effective in inhibiting the production of nitric oxide and other reactive oxygen species (ROS) which are involved in the pathogenesis of inflammation, septic shock and HIV infection. 1-Benzyl-1,4-dihydronicotinamide also inhibits light emission from cells. This effect is due to its ability to reduce the concentration of NADH and ATP, which are necessary for the light emitting reaction. The drug's mechanism of action is not well understood but it may be related to its ability to block dimethyl fumarate (DMF), an inhibitor of monoclonal antibody production. The physiological function of this drug is not yet well understood but it may be related to its ability to inhibit the proliferation of human immunodeficiency virus (HIV).</p>

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<p>Retinamide is a synthetic retinoid that is used for the treatment of skin cancer. It has been shown to induce apoptosis by activation of the c-jun N-terminal kinase (JNK) and p38 pathways, as well as by suppression of signaling through the phosphatidylinositol 3-kinase (PI3K)/Akt pathway. Retinamide also inhibits proliferation of HL60 cells and induces mitochondrial membrane depolarization in colon carcinoma cells. This drug has been shown to be a potent inhibitor of squamous cell carcinoma growth in vitro and in vivo, especially when combined with other chemotherapeutic agents. Retinamide has also been found to be effective against group P2 carcinomas, which are characterized by mutations in the BRAF gene.<br>Retinamide is metabolized by cytochrome P450 enzymes, leading to reactive metabolites that may cause toxic effects on cells. These metabolites can bind to DNA and cause strand breaks</p>

<p>Avenanthramide C is a potent polyphenolic compound that is isolated from the bark of the plant, Avena sativa. It has been shown to be an effective chemotherapeutic treatment for breast cancer and leukemia cells in vitro. Avenanthramide C has a hydroxyl group at its 6th carbon position and is a member of the class of compounds called avenanthramides. The biological properties of this compound have been examined using skin cells and it has been shown to exhibit significant activity against DNA polymerase, DNA binding activity, and enzyme activities. This compound also exhibits chemoattractant protein-like activity, which may be due to its ability to bind with high affinity to specific receptors on leukocytes.</p>

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<p>L-Lysine amide dihydrochloride is a crystalline compound that is used for the treatment of tumours. It has been shown to bind to the enzyme iridoid synthase, which is involved in the formation of imines and aldehydes. L-Lysine amide dihydrochloride also inhibits the production of staining compounds, such as fluorine and heterocycles. The compound may also be used cosmetically as an anti-aging agent because it can inhibit the production of collagenase and elastase, which cause degradation of collagen.</p>

<p>1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8-heptadecafluoro-N-methyloctane-1-sulfonamide is a perfluorinated sulfonate that is used as a surfactant in wastewater treatment and to package food. This compound is not water soluble and requires an organic solvent to dissolve it. It has been shown that the use of 1HFAFMS can reduce the amount of phosphates in packaging materials by up to 50%. 1HFAFMS also has been found to be safe for humans and does not accumulate in the environment. It does not bioaccumulate and is rapidly excreted through urine.</p>

<p>N-Phenylhydrazinecarbothioamide is a chemical compound that is used in wastewater treatment. It is an organic molecule that is composed of hydrophobic and hydrophilic parts. The hydrophobic part, which contains the phenyl group, binds to the hydrophobic region of the cell membrane and causes the cell to lyse. The hydrophilic part has an affinity for water and can be used as an electrode material in electrochemical impedance spectroscopy. N-Phenylhydrazinecarbothioamide also has been shown to have antibacterial properties against human pathogens, including Mycobacterium tuberculosis, Clostridium perfringens, and Escherichia coli O157:H7. The compound has been shown to inhibit cervical cancer cells by inhibiting protein synthesis through inhibition of ribosomal activity and fragmentation assay analysis showed that N-phenylhydrazinecarbothioamide binds to copper ions at a coordination geometry of</p>

<p>2-(3,4-Dimethoxyphenyl)-N-hydroxyacetamide is a versatile building block that can be used in the production of a wide range of research chemicals. It is also useful as a reagent or speciality chemical for the preparation of pharmaceuticals, agrochemicals and other industrial chemicals. 2-(3,4-Dimethoxyphenyl)-N-hydroxyacetamide is an intermediate that can be used to synthesize complex compounds such as benzodiazepines. This compound has been shown to have high quality and can be used as a reaction component in organic synthesis.<br>2-(3,4-Dimethoxyphenyl)-N-hydroxyacetamide has CAS number 33793-80-5 and its molecular weight is 237.27 g/mol.</p>

2,6-Dihydroxybenzamide is a compound that belongs to the class of antibiotics. It is used in the production of supplements and has been found to be biodegradable. This antibiotic has been shown to have a viscosity of 2cP at 25°C and a pH range of 3-9. The functional groups present in this compound are carboxylic acids, amines, and flavonoid derivatives. In addition, 2,6-dihydroxybenzamide has been shown to inhibit the growth of bacteria by inhibiting amine synthesis and by reacting with chloride ions. This antibiotic also shows inhibitory effects against heterocyclic amines that are generated from cooking meat at high temperatures. 2,6-Dihydroxybenzamide is metabolized through oxidation or reduction and can be excreted unchanged in urine or as glucuronide conjugates in the bile.

2-Phenyl-N-phenylacetamide is an amide that is a potent inhibitor of cholesterol acyltransferase. It has been shown to be effective in animal models of insulin resistance and hypertension, as well as in humans. 2-Phenyl-N-phenylacetamide inhibits the activity of cholesterol acyltransferase by competitive inhibition and thereby reduces the production of triglycerides. This drug also inhibits the synthesis of phospholipids and bile acids, which are important for fat digestion. 2-Phenyl-N-phenylacetamide reacts with phosphorus pentoxide to form phenoxyacetic acid, which is hydrolyzed to phenoxyacetate and phenol. The hydroxy group on phenol reacts with aryl halides to form aryl esters. These reactions lead to the formation of divalent hydrocarbon intermediates such as malonic acid, which can be used for energy production through oxidation or as precursors

<p>2-Iodoacetamide is a synthetic retinoid that binds to the DNA of cells, altering transcription. It also has been found to be effective in treating bowel disease and has been shown to have dna binding activity. The compound was synthesized by attaching iodine molecules to acetamide. 2-Iodoacetamide targets the protein thiols on the surface of cells, which are responsible for oxidation and damage due to reactive oxygen species (ROS). This compound is metabolized by alcohol dehydrogenase and can be used as a biological sample or natural compound.</p>

Cyclotheonamide A is a cyclopeptide, which is a type of secondary metabolite composed of non-standard amino acids arranged in a cyclic structure. It is naturally sourced from marine sponges, particularly Theonella sp., which are known for their rich and diverse repertoire of bioactive compounds. Cyclotheonamide A functions through the inhibition of serine proteases, a class of enzymes that play a significant role in numerous biological processes, including digestion, immune response, and blood coagulation.

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<p>5-Amino-1,3,4-thiadiazole-2-sulfonamide is a chemical compound that inhibits the growth of skin cancer cells. It has inhibitory properties against choroidal neovascularization induced by dorzolamide hydrochloride and other pharmacological agents. 5-Amino-1,3,4-thiadiazole-2-sulfonamide has also been shown to have antiangiogenic activity in vitro and in vivo assays. 5ATTS inhibits the growth of bacteria and fungi by inhibiting fatty acid synthesis. The drug also has been shown to be effective in treating diabetic neuropathy and fluorescein angiography associated with itchy eyes.</p>

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<p>2-Hydroxysalicylamide is a low-energy, small molecule that has shown to be an effective inhibitor of serine proteases. It binds to the active site of the protease, blocking catalysis and inhibiting the growth of cancer cells. 2-Hydroxysalicylamide has been shown to inhibit the transcriptional regulation of pro-inflammatory genes in a patterning assay and it inhibits tumor growth in a pain model. This drug also suppresses the expression of suppressor genes and can be used as an analgesic without causing side effects.<br>2-Hydroxysalicylamide is also a polarizer for tissues, meaning that it preferentially accumulates in tissues with high water content such as breast tissue. This property has been shown to be useful for imaging cancerous tumors.</p>

<p>4-Iodobenzenesulphonamide is a drug with antifungal and anticancer activity. The compound has been shown to inhibit the growth of cancer cells in vitro. It also has an antifungal effect in vitro, which is most likely due to its ability to inhibit the synthesis of ergosterol, a component of the cell membrane. 4-Iodobenzenesulphonamide may be used for the treatment of cervical cancer and vulvovaginal candidiasis. This drug does not show any serious side effects, but it has been shown to have some adverse effects on liver function tests and red blood cells.</p>

<p>3-Chlorobenzamide is an analytical reagent that is used for the separation and purification of organic compounds. It has been shown to be a catalyst for the reaction system in the dehydration of amides, amido, and halides. 3-Chlorobenzamide has also been suggested as a possible environmental pollutant due to its catalytic properties and ability to react with monoxide. The correlations between 3-chlorobenzamide concentrations in air and soil have also been studied extensively.</p>

<p>2,4-Dichloropyrimidine-5-carboxamide is a 2,4-dichloropyrimidine derivative. It is an intermediate in the synthesis of other compounds, and can be used as a building block in the synthesis of complex compounds. It is a versatile building block that can be used to make many different products. This chemical has been shown to have high quality and is useful as a research reagent or speciality chemical. 2,4-Dichloropyrimidine-5-carboxamide is also a useful intermediate for reactions involving nucleophilic substitution reactions and can serve as a scaffold for organic synthesis.</p>

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<p>Cyanamide is a nitrogen-containing organic compound that is used as a plant nutrient. It has been shown to increase the activity of enzymes in methyl ethyl x-ray crystal structures and locomotor activity in mice. Cyanamide is also used as an herbicide and chemical pesticide, with calcium as its main target. The cyanamide molecule binds to the calcium ion and undergoes a reaction mechanism that results in the release of ammonia gas, which is toxic to plants. In addition, cyanamide can cause kidney damage in humans due to its ability to inhibit protein synthesis.</p>

<p>2,3-Diaminobenzamide is a synthetic aromatic compound that is used as a radiation stabilizer. It is also an effective antimicrobial agent with reactive properties against bacteria and fungi. 2,3-Diaminobenzamide has been shown to have anti-cancer properties and can be used to treat inflammatory diseases such as rheumatoid arthritis or ulcerative colitis. The intramolecular hydrogen bond between the amide group and the benzene ring in 2,3-diaminobenzamide contributes to its stability and biological activity.</p>

<p>Emulgator; stabilizing surfactant used in cosmetics, pharmaceuticals, textiles</p>

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<p>AZD 1152 is an Aurora kinase inhibitor, which is a type of small-molecule therapeutic agent. It is derived from the pharmaceutical research conducted by AstraZeneca. Its primary mode of action involves the selective inhibition of Aurora B kinase, an enzyme crucial for the regulation of mitosis. By interfering with this enzyme, AZD 1152 disrupts the normal progression of cell division, leading to the inhibition of proliferation and induction of apoptosis in rapidly dividing cells.</p>

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Trifluoromethanesulfonamide is a strong acid that has been shown to inhibit the proteolytic activity of human secretase. It binds to a specific site on the enzyme and prevents it from cleaving the substrate. This inhibition slows down the progression of Alzheimer's disease, Parkinson's disease, and other related disorders. Trifluoromethanesulfonamide has also been shown to bind to metal hydroxides, such as iron hydroxide, which may be due to its ability to form hydrogen bonds with these metals. Structural analysis reveals that trifluoromethanesulfonamide contains a pyrazole ring and two chlorine atoms, one in the para position and one in the meta position.

Pantethine is a dietary supplement, which is a derivative of pantothenic acid, sourced from vitamin B5. As a biologically active compound, it undergoes conversion to pantetheine, which then forms coenzyme A (CoA) and acyl-carrier proteins. This conversion is critical, as CoA is an essential cofactor involved in numerous biochemical reactions that are integral to fatty acid metabolism, among other processes.

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<p>1-Naphthaleneacetamide is a plant growth regulator that belongs to the class of compounds known as auxins. It inhibits the production of chlorophyll and reduces photosynthetic activity in plants, thereby causing a decrease in chlorophyll content. 1-Naphthaleneacetamide has been shown to have genotoxic effects on human cells in tissue culture. This agent also has an effect on DNA damage and repair and can be used as an analytical method for determining the presence of surfactant sodium dodecyl (SDS) in urine samples by fluorescence spectrometry.</p>

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<p>2-Phenylacetamide is a solvent that can be used as a component in alkylation reactions. It is commonly used as a component of chlorinated solvents and has been shown to catalyze the reaction with benzyl chloride. 2-Phenylacetamide can be used to produce solar cells by sensitizing the surface of silicon wafers with this solvent. Researchers have also studied the alkylation reaction of phenylacetamide with methyl iodide and benzyl chloride, which can be carried out at room temperature and does not require any catalyst. This reaction was found to proceed well under gas chromatographic conditions.</p>

2-Phenyl-N-(phenylsulfonyl)acetamide is a fine chemical, useful intermediate and research chemicals. It has a CAS number of 92200-24-3. This compound can be used as a versatile building block in the synthesis of complex compounds with high quality and purity. 2-Phenyl-N-(phenylsulfonyl)acetamide can also be used as a reaction component in the synthesis of speciality chemicals or as a reagent.

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<p>Thioctamide is a drug that belongs to the class of drugs called sulfonylureas. It is an anti-diabetic drug that has been used for the treatment of insulin-resistant type II diabetes. Thioctamide binds to mitochondrial dehydrogenases and lipoamidases, inhibiting mitochondrial functions and energy metabolism. This leads to a decrease in cellular ATP levels, which can be measured by electrochemical impedance spectroscopy (EIS). The effects of thioctamide on cells can also be determined by examining the response of cells to different concentrations of thioctamide using a cell viability assay. This drug has been shown to inhibit the growth of HL60 cells, with IC50 values ranging from 2.6 µM to 6.4 µM depending on concentration. Thioctamide inhibits the expression of toll-like receptor 4 (TLR4) and integrin receptor β1 in HL60 cells, which may be due to its ability to act</p>

<p>Homoveratramide is a synthetic drug that is used as an antibacterial agent. It has a broad spectrum of activity against bacteria, fungi, and protozoa. Homoveratramide has been shown to be effective against both Gram-positive and Gram-negative bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, Salmonella enterica, Pseudomonas aeruginosa, and Klebsiella pneumoniae. Homoveratramide inhibits the synthesis of DNA by binding to the enzyme ribonucleotide reductase. This produces a bacteriostatic effect on the cell by halting DNA replication and transcription.</p>