Standard farmaceutici
Gli standard farmaceutici sono un insieme completo di materiali di riferimento essenziali per garantire la sicurezza, l'efficacia e la qualità dei prodotti farmaceutici. Questa categoria include standard per ingredienti farmaceutici attivi (API), che sono i componenti principali responsabili degli effetti terapeutici. Inoltre, copre composti e metaboliti rilevanti sia per l'industria farmaceutica che veterinaria, fornendo punti di riferimento per la misurazione e l'analisi precisa di queste sostanze. Gli standard di controllo delle nitrosammine sono cruciali per rilevare e mitigare le nitrosammine potenzialmente dannose nelle formulazioni di farmaci. Gli standard di tossicologia aiutano a valutare la sicurezza e i potenziali effetti avversi dei composti farmaceutici. Inoltre, gli standard per attivatori e inibitori enzimatici sono vitali per la ricerca e lo sviluppo, consentendo studi precisi delle vie biochimiche e dei meccanismi d'azione dei farmaci. Questi standard farmaceutici sono strumenti indispensabili per la conformità normativa, il controllo di qualità e la ricerca, garantendo che i prodotti farmaceutici soddisfino rigorosi criteri di sicurezza ed efficacia.
Sottocategorie di "Standard farmaceutici"
- APIs per la ricerca e le impurità(273.647 prodotti)
- Attivatori e inibitori enzimatici(2.827 prodotti)
- Nitrosamine(2.605 prodotti)
- Composti e metaboliti farmaceutici e veterinari(2.602 prodotti)
- Tossicologia(13.652 prodotti)
Trovati 7836 prodotti di "Standard farmaceutici"
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(S)-(-)-Carvedilol
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications The optically active isomer of Carvedilol (C184625), a nonselective ß-adrenergic blocker with a1-blocking activity. An antihypertensive used in the treatment of congestive heart failure.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990),<br></p>Formula:C24H26N2O4Colore e forma:Off White SolidPeso molecolare:406.47Caffeidine Acid Sodium Salt
CAS:Prodotto controllato<p>Applications Caffeidine Acid is a potential degradation product from the hydrolysis of Caffeine (C080100) under alkaline environment.<br>References Zubair, U.M., et al.: Anal. Profiles Drug Subs., 15, 71 (1986); Cherrah, Y., et al.: Biochem. Pharmacol., 37, 1311 (1988);<br></p>Formula:C8H11N4O3·NaColore e forma:NeatPeso molecolare:234.19(S)-(+)-Ibuprofen-d3
CAS:Prodotto controllato<p>Applications A labelled nonsteroidal anti-inflammatory drug (NSAID); activity resides primarily in the (S)-isomer.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),<br></p>Formula:C13H15D3O2Colore e forma:NeatPeso molecolare:209.3Torsemide-d7
CAS:Prodotto controllato<p>Applications Labelled Torsemide (T548750). Used as a diuretic.<br>References Lesne, M., et al.: In. J. Clin. Pharmacol. Ther. Toxicol., 20, 382 (1982), Brater, D.C., et al.: Clin. Pharmacol. Ther., 42, 187 (1987),<br></p>Formula:C162H7H13N4O3SColore e forma:NeatPeso molecolare:355.46α-Tocopherol Phosphate Disodium Salt
CAS:Prodotto controllatoFormula:C29H49Na2O5PColore e forma:White To Off-WhitePeso molecolare:554.65Cholesteryl Acetate Dibromide(Mixture of Diastereomers)
CAS:Prodotto controllato<p>Applications Cholesteryl Acetate Dibromide is an brominated intermediate in the synthesis of Cholesterol (C432501) derivatives.<br>References Kandutsch, A.A., et al.: J. Biol. Chem., 249, 6057 (1974);<br></p>Formula:C29H48Br2O2Colore e forma:NeatPeso molecolare:588.52-(9H-Carbazol-1-yl)acetic Acid
CAS:Prodotto controllatoFormula:C14H11NO2Colore e forma:NeatPeso molecolare:225.243Urolithin C
CAS:<p>Stability Hygroscopic<br>Applications Urolithin C is used in biological studies to evaluate the metabolite antioxidant activity.<br>References Ishimoto, H., et. al.: Bioorg. Med. Chem. Lett., 21, 5901 (2011);<br></p>Formula:C13H8O5Colore e forma:NeatPeso molecolare:244.2N-Desmethyl Azelastine
CAS:Prodotto controllato<p>Applications The main phase I metabolites of Azelastine.<br>References Adusumalli, V., et al.: Drug Metab. Dispos, 20, 530 (1992), Mano, N., et al.: J. Pharm. Biomed. Anal., 12, 557 (1994), Baldwin, S., et al.: Xenobiotica, 25, 261 (1995), Kobayashi, K., et al.: J. Pharmacol. Exp. Ther., 280, 927 (1997),<br></p>Formula:C21H22ClN3OColore e forma:NeatPeso molecolare:367.87Gentiopicroside
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Gentiopicroside is an anticonvulsant agent present in plant extracts.<br>References Mahendran, G. et al.: Biomed. Res. Int., 2015, 542385 (2014);<br></p>Formula:C16H20O9Colore e forma:NeatPeso molecolare:356.32(2R,3S)-N-Benzoyl-3-phenyl Isoserine Methyl Ester
CAS:Prodotto controllato<p>Applications (2R,3S)-N-Benzoyl-3-phenyl Isoserine Methyl Ester is an intermediate in the preparation of potent anticancer drug Paclitaxel (P132500) used to study the location of the binding sites.<br>References Paal, K. et al.: Bioorg. Med. Chem., 15, 1323 (2007); Krawczyk, E. et al.: J. Pharm. Pharmacol., 57, 791 (2005);<br></p>Formula:C17H17NO4Colore e forma:Off White PowderPeso molecolare:299.32(S)-Duloxetine Phthalamide
CAS:Prodotto controllato<p>Impurity Duloxetine Phthalamide Impurity<br>Applications (S)-Duloxetine Phthalamide is an impurity of (S)-Duloxetine present with enteric polymer hydroxypropylmethylcellulose phthalate (HPMCP) in dosage formulations.<br>References Jansen, P.J., et al.: J. Pharmaceut. Sci., 87, 81 (1998),<br></p>Formula:C26H23NO4SColore e forma:White To Off-WhitePeso molecolare:445.53Simvastatin Hydroxy Acid Ethyl Ester
CAS:<p>Applications An impurity in Simvastatin (S485000).<br>References Sankar, D. et al.: Asian J. Chem., 21, 4294 (2009); Vuletic, M. et al.: J. Pharmac. Biomed. Anal., 37, 715 (2005);<br></p>Formula:C27H44O6Colore e forma:Off-WhitePeso molecolare:464.639-Chloro Triamcinolone Acetonide
CAS:<p>Applications Triamcinolone Acetonide (T767165) impurity.<br>References Laurent, H., et al.: J. Steroid Biochem., 6, 185 (1975),<br></p>Formula:C24H31ClO6Colore e forma:WhitePeso molecolare:450.95Roflumilast N-Oxide
CAS:Prodotto controllato<p>Applications Roflumilast-N-oxide is the active metabolite of Roflumilast (R639700).<br>References Chiba, M., et al.: Drug Metab. Dispos., 25, 1022 (1997), Jarvis, B., et al.: Drugs, 59, 891 (2000),<br></p>Formula:C17H14Cl2F2N2O4Colore e forma:NeatPeso molecolare:419.21(1R)-(+)-a-Pinene (~80% ee)
CAS:Prodotto controllato<p>Applications (1R)-(+)-α-Pinene is used in hydroboration reactions and the reduction of ketones.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brown, H. et al.: J. Org. Chem., 50, 1384 (1985);<br></p>Formula:C10H16Colore e forma:NeatPeso molecolare:136.23Pravastatin Lactone
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Pravastatin Lactone is a metabolite of Pravastatin (P702000).<br>References Boberg, M., et al.: Drug Metab. Dispos., 25, 321 (1997), Neuvonen, P., et al.: Clin. Pharmacol. Ther., 63, 332 (1998), Boyd, R., et al.: J. Clin. Pharmacol., 40, 91 (2000),<br></p>Formula:C23H34O6Colore e forma:NeatPeso molecolare:406.51Uric Acid-13C,15N2
CAS:Prodotto controllatoFormula:CC4H415N2N2O3Colore e forma:Off-White To Light YellowPeso molecolare:171.09Atropine Sulfate Monohydrate
CAS:Prodotto controllato<p>Applications Mydriatic; antispasmodic; used in preanesthetic medication.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brown, R.V., et al.: Br. J. Pharmacol., 15, 170 (1960), Shutt, L.E., et al.: Anaesthesia, 34, 476 (1979), Hinderling, P.H., et al.: J. Pharm. Sci., 74, 703 (1985),<br></p>Formula:C17H23NO3·H2O·H2O4SColore e forma:White To Light YellowPeso molecolare:694.83Didemethyl Mifepristone
CAS:Prodotto controllato<p>Applications A metabolite of Mifepristone.<br>References Heikinheimo, O., et al.: J. Steroid Biochem., 26, 279 (1987), Brogden, R., et al.: Drugs, 45, 384 (1993), Shi, Y., et al.: Contraception, 48, 133 (1993), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Gainer, E., et al.: Steroids, 68, 1005 (2003),<br></p>Formula:C27H31NO2Colore e forma:NeatPeso molecolare:401.54Hydrocortisone 17-Butyrate 21-Propionate
CAS:Prodotto controllato<p>Applications A synthetic adrenocorticosteroid that acts as an anti-inflammatory and anti-pruritic agents. It is used as a topical for the treatment of dermatologic disorders such as atopic dermatitis and psoriasis.<br>References Mason, J. et al.: Br. J. Dermatol., 146, 351 (2002); Sears, H.W. et al.: Clin. Therap., 19, 710 (1997); Otomo, Y.Z. et al.: Nip. Yakur. Zas., 78, 647 (1981);<br></p>Formula:C28H40O7Colore e forma:White To Off-WhitePeso molecolare:488.61Gibberellin A6
CAS:Prodotto controllato<p>Stability Moisture Sensitive<br>Applications Gibberellin A6 is a derivative of the plant hormone Gibberellin which regulates growth and various developmental processes.<br>References Stolp, C.F., et al.: Plant Cell Physiol, 18, 721-8 (1977)<br></p>Formula:C19H22O6Colore e forma:NeatPeso molecolare:346.374,4'-[(Phenylmethylene)bis[(2,5-dimethyl-4,1-phenylene)-2,1-diazenediyl]]bis[3-hydroxy-N-phenyl-2-naphthalenecarboxamide
CAS:Prodotto controllato<p>Applications 4,4'-[(Phenylmethylene)bis[(2,5-dimethyl-4,1-phenylene)-2,1-diazenediyl]]bis[3-hydroxy-N-phenyl-2-naphthalenecarboxamide, can be used for the preparation of paper strips containing indicator dyes, which change color upon exposure to certain chemical warfare agents but not to common solvents.<br>References Nestmann, E., et al.: Carcinogenesis, 2, 879 (1981);<br></p>Formula:C57H46N6O4Colore e forma:NeatPeso molecolare:879.01Androstenediol 3-Acetate
CAS:Prodotto controllato<p>Applications Androstenediol 3-Acetate is an intermediate in the synthesis of Pregnenolone (P712200) which is a steroid hormone involved in the steroidogenesis of progesterone, mineralocorticoids, glucocorticoids, androgens, and estrogens.<br>References Stastna, E., et al.: Steroids., 75, 721 (2010);<br></p>Formula:C21H32O3Colore e forma:NeatPeso molecolare:332.486β-Hydroxy Norethindrone Acetate
CAS:Prodotto controllato<p>Impurity Norethindrone Acetate EP Impurity F<br>Applications 6β-Hydroxy Norethindrone Acetate (Norethindrone Acetate EP Impurity F) is an oxidative product of the drug Norethindrone (N676000). Norethindrone impurity.<br>References Reif, V., et al.: Pharmaceutical Res., 4, 54 (1987), Rao, P., et al.: Steroids, 59, 621 (1994),<br></p>Formula:C22H28O4Colore e forma:Off-WhitePeso molecolare:356.46Mefruside
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Mefruside is a diuretic used for the treatment of edema and hypertension.<br>References Johansen, A., et al.: Euro. J. Epidemiol., 27, 63 (2012); Hasegawa, Y., et al.: Blood. Press. Supple., 1, 10 (2010);<br></p>Formula:C13H19ClN2O5S2Colore e forma:Off-WhitePeso molecolare:382.885-Chloronaphthalene-2-sulfonyl Chloride
CAS:Prodotto controllato<p>Applications 5-Chloronaphthalene-2-sulfonyl Chloride (cas# 89108-45-2) is a compound useful in organic synthesis.<br></p>Formula:C10H6Cl2O2SColore e forma:NeatPeso molecolare:261.12Sodium 2,2'-Methylene-bis(4,6-di-tert-butylphenyl)phosphate
CAS:Prodotto controllato<p>Applications Sodium 2,2'-Methylene-bis(4,6-di-tert-butylphenyl)phosphate is an organophosphate nucleating agent.<br>References Li, J., et al.: Suliao, 43, 47-50 (2014);<br></p>Formula:C29H42O4P·NaColore e forma:White PowderPeso molecolare:508.60Hydroxy Dehydro Nifedipine Lactone
CAS:Prodotto controllatoFormula:C16H12N2O6Colore e forma:NeatPeso molecolare:328.28Indole-3-carboxylic Acid
CAS:Prodotto controllatoFormula:C9H7NO2Colore e forma:NeatPeso molecolare:161.16(3R,5R)-Rosuvastatin Sodium Salt
CAS:<p>Impurity Rosuvastatin EP Impurity B<br>Stability Hygroscopic<br>Applications A diastereomer of Rosuvastatin (R700500) used for treatment, prevention and combination therapy of lipid-related disorders. Rosuvastatin EP Impurity B<br></p>Formula:C22H27FN3NaO6SColore e forma:White To Light YellowPeso molecolare:503.52Methyl Benzilate
CAS:Prodotto controllato<p>Applications Methyl Benzilate is a reactant in the synthesis of Trimethadione (T796155), an anticonvulsant and antiepileptic agent used in the treatment of pregnant women. Prenatal exposure to snti-epileptic drugs (AEDs) has indicated increased risk of major or minor congenital malformation.<br>References Pastore, V., et. al.: Bioorg. Med. Chem., 21, 841 (2013); Ahir, B. et al.: Toxicol. Vitro., 28, 948 (2014); Pastore, V. et al.: Bioorg. Med. Chem., 21, 841 (2013)<br></p>Formula:C15H14O3Colore e forma:Off White PowderPeso molecolare:242.272-[3-(Aminosulfonyl)-4-chlorobenzoyl]-benzonic Acid
CAS:Prodotto controllato<p>Applications 2-[3-(Aminosulfonyl)-4-chlorobenzoyl]-benzonic Acid is a potential metabolite of Chlorthalidone.<br>References Salado C., et al.: J. Chromatography. Biomed. App., 690, 195 (1997);<br></p>Formula:C14H10ClNO5SColore e forma:NeatPeso molecolare:339.75(±)-trans-α-Bergamotene
CAS:Prodotto controllato<p>Applications (±)-trans-α-Bergamotene is an essential oil from medicinal plants of Cameroon.<br>References Boyom, F. F., et al.: Phytochem., 64, 1269 (2003);<br></p>Formula:C15H24Colore e forma:NeatPeso molecolare:204.351Diamino-5-phenylthiazole Hydrobromide
CAS:Prodotto controllato<p>Applications Diamino-5-phenylthiazole Hydrobromide is an phenylthiazole derivative used in the preparation of antiallergic and antiinflammatory agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ban, M. et al.: Bioorg. Med. Chem., 6, 1069 (1998);<br></p>Formula:C9H9N3S·BrHColore e forma:NeatPeso molecolare:272.164-Aminoacetophenone
CAS:Prodotto controllato<p>Applications A novel utilization of aminophenone derivative in toxicology, for treating intoxications with cyanogenic toxic substances.<br>References Donoghue, N., et al.: Eur. J. Biochem., 60, 1 (1975), Chen, Y., et al.: J. Bacteriol., 170, 781 (1988),<br></p>Formula:C8H9NOColore e forma:Yellow SolidPeso molecolare:135.16β-Lapachone (>90%)
CAS:Prodotto controllato<p>Applications β-Lapachone is a naturally occurring quinone obtained from the bark of the lapacho tree (Tabebuia avellanedae) with cancer chemopreventive properties. Induces apoptosis in HL-60 and human prostate cancer cells.<br>References Renslo, A., et al.: Nat. Chem. Biol., 2, 701 (2006), Hopkins, A., et al.: Nat. Chem. Biol., 4, 682 (2008), Stuart, K., et al.: J. Clin. Invest., 118, 1301 (2008), Martin, R., et al.: Science, 25, 1680 (2009),<br></p>Formula:C15H14O3Purezza:>90%Colore e forma:Orange SolidPeso molecolare:242.27Campesteryl Ferulate
CAS:Prodotto controllato<p>Applications Campesteryl Ferulate is a component of γ-oryzanol with antioxidant activities.<br>References Xu, Z., et al.: J. Agric. Food Chem., 49, 2077 (2001);<br></p>Formula:C38H56O4Colore e forma:NeatPeso molecolare:576.85Hematoporphyrin Dihydrochloride
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Hematoporphyrin dihydrochlordie (cas# 17696-69-4) is a useful research chemical.<br></p>Formula:C34H38N4O6·2ClHColore e forma:NeatPeso molecolare:671.61Hydroflumethiazide
CAS:Prodotto controllato<p>Applications Antihypertensive; diuretic.<br>References Piala, J.J., et al.: J. Pharmacol. Exp. Ther., 134, 273 (1961), Orzech, C.E., et al.: Anal. Profiles Drug Subs., 7, 297 (1978),<br></p>Formula:C8H8F3N3O4S2Colore e forma:NeatPeso molecolare:331.29Glycochenodeoxycholic Acid 3-Sulfate Disodium Salt
CAS:<p>Stability Hygroscopic<br>Applications A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic.<br>References Parmentier, G. , et al.: Steroids, 30, 583 (1977), Tserng, K.Y., et al.: Lipids, 13, 479 (1978),<br></p>Formula:C26H41NNa2O8SColore e forma:White To Off-WhitePeso molecolare:573.65Ouabain-d3 (Major)
CAS:Prodotto controllato<p>Applications Labelled Ouabain (O714500). A cardiac glycoside that inhibits Na(+)/K(+) ATPase. It regulates transcription of MDR (increase, Pgp) and MRP (increase MRP1 and decrease CFTR, cyctic fibrosis transport receptor or cAMP-activated Cl- channel) genes, also alters localization of MRP1.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Padilha, A.S. et al.: Clin. Exp. Pharmacol. Physiol., 35, 801 (2008); Blaustein, M.P. et al.: Clin. Exp. Hypertens. 20, 691 (1998); van Huysse, J.W. et al.: Clin. Exp. Hypertens. 20, 657 (1998);<br></p>Formula:C29H41D3O12Colore e forma:White To Off-WhitePeso molecolare:587.67Oxindole-3-acetic Acid-d4
CAS:Prodotto controllatoFormula:C10D4H5NO3Colore e forma:NeatPeso molecolare:195.208Dipropofol
CAS:<p>Impurity Propofol EP Impurity E; Propofol USP Related Compound A<br>Applications Dipropofol (Propofol EP Impurity E) is a dimeric derivative of Propofol (P829750). Dipropofol is an antibacterial agent with strong activity againts Gram-positive bacteria. Dipropofol also displays antioxidant and radical scavenging activity. Propofol USP Related Compound A.<br>References Ogata, M. et al.: Chem. Pharm. Bull., 53, 344 (2005); Ogata, M. et al.: Biol. Pharmac. Bull., 30, 1565 (2007);<br></p>Formula:C24H34O2Colore e forma:NeatPeso molecolare:354.532-Naphthol-6,8-disulfonic Acid Potassium Salt
CAS:<p>Applications 2-Naphthol-6,8-disulfonic Acid Potassium Salt is a salt of 2-Naphthol-6,8-disulfonic Acid (N368023). 2-Naphthol-6,8-disulfonic acid is a useful research chemical for organic synthesis and other chemical processes. A reagent used in the preparation of food dyes with numerous applications.<br>References Baltac, T., et al.: Revista de Chimie, 63, 618 (2012)<br></p>Formula:C10H8O7S2•x(K)Colore e forma:Off-WhitePeso molecolare:304.30391Methyl Lithocholate
CAS:Prodotto controllato<p>Applications Methyl Lithocholate is an derivative of Lithocholic Acid (L469180),a cholic acid derivative as TGR5 modulator. Found in ox bile, human bile, rabbit bile, and in ox and pig gallstones.<br>References Roleira, F.M., et al.: Lett. Drug. Design. Discovery., 7, 610 (2010);<br></p>Formula:C25H42O3Colore e forma:NeatPeso molecolare:390.60Des[5-(2-dimethylamino)ethyl] Diltiazem
CAS:Prodotto controllato<p>Applications Diltiazem (D460620) intermediate (impurity B).<br>References Chaffman, M., et al.: Drugs, 29, 387 (1985), Kamath, B., et al.: J. Pharm. Biomed. Anal., 11, 407 (1993), Chankvetadze, B., et al.: J. Pharm. Biomed. Anal., 27, 161 (2002),<br></p>Formula:C18H17NO4SColore e forma:NeatPeso molecolare:343.40O-Methyl Atorvastatin Calcium Salt
CAS:Prodotto controllato<p>Impurity Atorvastatin EP Impurity G<br>Applications Atorvastatin derivative.<br></p>Formula:C34H36FN2O5·CaColore e forma:Off-WhitePeso molecolare:1183.39Rosuvastatin tert-Butyl Ester
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Rosuvastatin tert-Butyl Ester, is a metabolite of Rosuvastatin (R700500) a selective, competitive HMG-CoA reductase inhibitor.<br>References Watanabe, M., et al.: Bioorg. Med. Chem., 5, 437 (1997), Lee, E., et al.: Clin. Pharmacol. Ther., 78, 330 (2005), Ferdinand, K.C., et al.: Am. J. Cardiol., 97, 229 (2006),<br></p>Formula:C26H36FN3O6SColore e forma:NeatPeso molecolare:537.64
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