Standard farmaceutici

Applications Intermediate for the synthesis of 2-Hydroxymethyl Loratadine.
References Cerrada, V., et al.: ARKIVOC, 9, 200 (2005).

Applications 6,9,12,15,18-Heneicosapentaynoic Acid Methyl Ester is a methyl analog of 6,9,12,15,18-Heneicosapentaynoic Acid.

Applications 7-Methoxy-1-naphthalenol is used in the synthesis of Agomelatine (A430000).

Applications 3,20-Disemicarbazone-11β,17,21-trihydroxy-pregna-1,4-diene-3,20-dione can be used in synthetic preparation of prednisolone acetate. Intermediate in the synthesis of prednisolone.
References Liao, J., et al.: Faming Zhuanli Shenqing, CN 105503986 A 20160420 (2016)

Applications 1-Naphthyl Acetate (cas# 830-81-9) is a useful research chemical.

Applications 3-Bromo-2-naphthoic Acid is used as a reagent for prepartion of isochromanones.
References Wen, Z.K., et al.: Advanced Synthesis and Catalysis, 361,963 (2019)

Applications Intermediate in the production of Losartan impurities

Stability Light Sensitive
Applications 3,3'-Bipyridine-6,6'-dicarbonitrile

Applications (αE)-α-[(3,4-Dihydroxy-5-nitrophenyl)methylene]-β-oxo-1-piperidinepropanenitrile is an impurity of Entacapone (E558500), a peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian.
References Karlsson, M., et al.: J. Pharm. Biomed. Anal., 10, 593 (1992), Nissinen, E., et al.: Arch. Pharmacol., 346, 262 (1992), Wikberg, T., et al.: Eur. J. Drug Metab. Pharmacokinet., 18, 359 (1993),

Applications 2,6-dibromoanthracene (cas# 186517-01-1) is a useful research chemical.

Applications N-(Cinnamoyl)-4-methoxyaniline (cas# 76228-15-4) is a compound useful in organic synthesis.

Applications (2-Deoxy-β-D-erythro-pentofuranosyl)urea is used as a reactant in the deoxyguanosine oxidation by singlet oxygen.
References Cadet, J., et al.: Photochem, Photobiol., 28, 661 (1978)

Applications (5S)-5-Hydroxy-6-heptynoic Acid 1-Methylethyl Ester is an intermediate in synthesizing Resolvin E1 Sodium Salt (R144690), which is an omega-3 polyunsaturated fatty acid derivative that exhibits potent anti-inflammatory, pro-resolution, and anti-nociceptive effects. Resolvin E1 has been shown to inhibit neuropathic pain and spinal cord microgial activation following peripheral nerve injury.
References Xu, Z.Z. et al.: J. Neuroimm. Pharamcol., 2012; Schwab, J.M. et al.: Nature, 447, 869 (2007);

Applications 5-(BROMOMETHYL)-2-NITROPYRIDINE (cas# 448968-52-3) is a useful research chemical.

Applications β-Elemene is an active constituent of Delonix regia and an anti-inflammatory agent. β-Elemene is a useful compound for investigating the toll-like receptor 4 signaling pathway and the inhibition of TNF-​a, IL-​1b, IL-​6 and IL-​12 expressions.
References Satajit, P., et al.: Int Immunopharmacol 34, 199 (2016);

Applications L-2-Nitrophenylalanine is a derivative of L-phenylalanine (P319415), and is used in the photocleavage of polypeptide backbones. L-Phenylalanine is an essential amino acid. L-Phenylalanine is biologically converted into L-tyrosine, another one of the DNA-encoded amino acids, which in turn is converted to L-DOPA and further converted into dopamine, norepinephrine, and epinephrine.
References Peters, F. et al.: Chem. Biol., 16, 148 (2009); Hollunger, G. et al.: Acta Pharmacol. Toxicol., 34, 391 (1974); Bagchi, S.P. et al.: Biochem. Pharmacol., 26, 900 (1977);

Applications 6,7-Dimethoxynaphth-1-yl Trifluoromethanesulfonate is used as a reagent in the synthesis of tripeptide Grb2-SH2 domain inhibitors containing 4-(phosphonomethyl)phenylalanine and naphthalene.
References Schoepfer, J., et al.: Bioorg. Med. Chem. Lett., 11, 1201 (2001)

Applications Anthracene is obtained from coal tar. It is an important source of many dyes.This compound is a contaminant of emerging concern (CECs)
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Labelled Dihydroisoferulic Acid 3-O-Sulfate, the sulfate conjugate of Dihydroisoferulic Acid (H946365). Dihydroisoferulic Acid 3-O-Sulfate is a minor circulating metabolite in human plasma after coffee consumption.
References Fumeaux, R. et al.: Org. Biomol. Chem., 8, 5199 (2010); Redeuil, K. et al.: J. Chrom. A, 1218, 4678 (2011);

Stability Hygroscopic
Applications Ginsenoside C-K is reported to exhibit anti-wrinkle effects. Also, it potentiates tumor necrosis factor (TNF)-related apotosis-inducing ligand (TRAIL)-induced apotosis in HCT116 colon cancer.
References Han, S., et al.: J. Cell. Biochem., (2017); Chen, L., et al.: Cell Death Diff., 7, 2334 (2016)

Applications 1,5-Dinitronaphthalene-d6 (CAS# 1219804-48-4) is a useful isotopically labeled research compound.

Applications Isotope labelled N-1-Naphthylethylenediamine Dihydrochloride, is an organic building block used for the chemical synthesis. It can also be used as highly selective organic fluorescent probe for azide ion.
References Sahana, A., et al.: Analyst , 137, 1544 (2012);

Applications 2-Isonitrosoacetophenone is used to make a complex with copper and amino acids. These complexes has shown to have more antimicrobial activities against gram positive bacteria than gram negative bacteria and the complexes also have antioxidant activity.
References Tidjani-Rahmouni, N., et. al.: J. Mol. Struct., 1075, 254 (2014)

Applications N,N'-Bis[3-(trifluoromethyl-4-cyanophenyl)thiourea can be obtained from 5-Amino-2-cyanobenzotrifluoride (A603630) which is used for the preparation of benzene derivatives as non-steroidal androgen receptor modulators.
References Xiao, H.-Y., et al.: Bioorg. Med. Chem. Lett., 20, 4491 (2010)

Applications 4-Nitrobiphenyl-2’,3’,4’,5’,6’-d5 (cas# 64421-02-9) is a compound useful in organic synthesis.

Applications 4,4'-(1Z)-Diaminostilbene-2,2'-disulfonic Acid Disodium Salt is a reactant in the synthesis of (arylamino)triazinylamino-substituted stilbenedisulfonic acid, to be used as an optical brightener.
References Okuom, Macduff, et al.: Inter. J. of Org. Chem., 3(4), 256-261 (2013)

Applications 2-Bromo-2’-hydroxyacetophenone (cas# 2491-36-3) is a compound useful in organic synthesis.
References Kumar, S., et al.: J. Med. Chem., 51, 4968 (2008), Emami, S., et al.: Bioorg. Med. Chem. Lett., 18, 141 (2008),

Applications (4-Chloro-2-methylphenoxy)acetic Acid-d3 is the deuterated version of (4-Chloro-2-methylphenoxy)acetic Acid (C369470), which is a herbicide.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Elliott, B., et al.: Mutagenesis, 20, 3 (2005); Pfleeger, T., et al.: Environ. Toxicol. Chem., 30, 455 (2010);

Applications 3,5-Diisopropylsalicylic Acid is used in preparation of Benzamides as LRH-1 modulators.
References England, Pamela M., et al.: PCT Int. Appl., (2017);

Applications N,N'-Bis[2-(2-hydroxyethoxy)ethyl]-urea can be synthesized from 2-(2-Aminoethoxy)ethanol (A609095), a widely used reactant that has been used in the preparation of TD-4306 as long-acting β2-agonist for asthma and COPD therapy.
References Mckinnell, R.M., et. al.: Bioorg. Med. Chem. Lett., 24, 2871 (2014)

Applications meso-2,3-Dimercaptosuccinic Acid-1,4-13C2 is the labeled version of meso-2,3-Dimercaptosuccinic Acid-1,4 which is used as a chelating agent and masking agent for cadmium in EDTA titration of zinc.
References Cavanillas, S., et al.: Anal. Chim. Acta., 746, 47 (2012); Liu, Y.X.,et al.: Adv. Materials. Res., 455, 1221 (2012); Banner, B., et al.: Clin. Toxicol., 50, 266 (2012);

Applications Hexocyclium Iodide-d3 is labelled Hexocyclium Iodide (H295660) which is an antimuscarinic.
References Waelbroeck, M., et al.: Brit. J. Pharm., 98, 197 (1989)

Applications 2-Phenylglutaric Anhydride (cas# 2959-96-8) is a useful research chemical.

Applications 4'-Amino-2-bromoacetophenone is a useful reagent for the synthesis of novel VO(II)- triazole complexes.
References El-Metwaly, N., et al.: J. Mol. Struct., 1190, 86 (2019)

Applications 1-(2-chloro-5-nitrophenyl)-2,5-dihydro-1H-pyrrole-2,5-dione (cas# 313069-92-0) is a useful research chemical.

Applications 2,2'-Bipyridyl-d8 was a useful compound in the NMR study of soft porous nanocrystal and a bulk crystal.
References Hijikata, Y., et al.: Chem. Commun. (Cambridge, UK), 47, 7632 (2011)

Applications 3,3'-dithiobis(propionohydrazide) (cas# 50906-77-9) is a useful research chemical.

Applications Testosterone Octanoate-d15 is the isotope analog of Testosterone Octanoate. Testosterone Octanoate is a metabolite of tesosterone (T155000), which is used in biological studies to determine the hemolytic and lipophilic activity of this anabolic steroid.
References Biagi, G.L., et al.: J. Med. Chem., 13, 944 (1970); Biagi, G. L., et al.: J. Med. Chem., 18, 873 (1975)

Applications [1,1'-Biphenyl]-3,3',4,4'-tetracarboxylic acid is a useful research chemical for organic synthesis and other chemical processes.
References Wu, X., et al.: Huaxue Shiji, 39, 1015 (2017); Wang, C., et al.: J. Mol. Struct., 1080 (2015)

Stability Hygroscopic
Applications Hematoporphyrin dihydrochlordie (cas# 17696-69-4) is a useful research chemical.

Applications 13-cis-β-Carotene-d5 is labelled 13-cis-β-Carotene (C184225) which is an isomer of β-Caroten (C184250). Carrots are one of the highest dietary sources of β-carotene and are naturally high in the (all-E)-β-carotene isomer, which has higher bioavailability, provitamin A activity, and antioxidant capacity compared to Z (cis) isomers.
References Chen, B., et al.: J. Agric. Food Chem., 43, 1912 (1995), During, A., et al.: J. Lipid Res., 43, 1086 (2002), Marx, M., et al.: Food Chem. 83, 609 (2003)

Applications Carbon 13 Labelled analogue of Adenosine (A280400), a purine nucleoside that plays an important role in various biochemical processes.
References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010)

Applications 2,4,6-Trichloro-N-methoxy-α-methylbenzeneethanamine is an intermediate in synthesizing Pydiflumetofen (P999040), which is used in the preparation of carboxamides as plant growth enhancers in crops.
References Haas, U.J.; et al.: PCT Int. Appl. 34pp. Patent 2013 CODEN:PIXXD2

Applications 5-Methyl-7-methoxyisoflavone (cas# 82517-12-2) is a useful research chemical.

Applications DL-Methionine-2-d1 (CAS# 67866-74-4) is a useful isotopically labeled research compound.

Applications N-[(S)-(4-Nitrophenoxy)phenoxylphosphinyl]-1-ethylpropylester-L-Alanine-D4 is a labelled compound form N-[(S)-(4-Nitrophenoxy)phenoxylphosphinyl]-1-ethylpropylester-L-Alanine cas(1884206-50-1)

Applications 2-(4-Nitrophenyl-d4)propane (CAS# 1219803-36-7) is a useful isotopically labeled research compound.

Applications 2,2'-Bipyridine-4,4'-dicarboxamide

Stability Temperature Sensitive
Applications 1,3-Dimethyl-3-nitrosourea is a carcinogen.
References Luan, F., et al.: Chem. Res. Toxicol., 18, 198 (2005); Hasegawa, R., et al.: Cancer Lett., 123, 185 (1998)

Applications 2-Bromo-6-chloro-4-pyridinecarboxylic Acid Methyl Ester, can be used as an intermediate in the preparation of Trifluoromethyl-Substituted pyridines, possessing wide range of bioactivites.
References Cottet, F., et al.: Eur. J. Org. Chem., 327 (2002);

Applications 1,3,5-Tri(1-naphthyl)benzene (cas# 7059-70-3) is a useful research chemical.

Applications 4-Hydroxy-4’-(trimethylacetoxy)benzophenone (cas# 114031-67-3) is a compound useful in organic synthesis.