Standard farmaceutici

Stability Light Sensitive
Applications (E)-Cinnamyl 3-aminobut-2-enoate (cas# 103909-86-0) is a useful research chemical.

Applications Methyl trans-Cinnamate-d7 (CAS# 2022152-96-9) is a useful isotopically labeled research compound.

Applications 2-Bromo-4'-fluoroacetophenone-2',3',5',6'-d4 (CAS# 1219803-30-1) is a useful isotopically labeled research compound.

Applications (R)-(-)-Carvone-d4 is an intermediate in synthesizing (+)-Limonene-d5 (L461742). It is present in blood oranges which show inhibition of angiogenesis in human colon cancer cells. Extracted from the oils of Mentha spicata it shows antimicrobial activity.
References Chidambara Murthy, K. et al.: Life Sci.,91, 429 (2012); Aggarwal, K. et al.: Flav. Frag. J., 17, 59 (2002)

Applications Homogentisic Acid γ-Lactone (cas# 2688-48-4) is a compound useful in organic synthesis.

Applications Tetrabromobisphenol A Allyl Ether is a brominated flame retardant.
References Riess, M., et al.: J. Chromat. A, 827, 65 (1998); Andersson, P., et al.: Environ. Toxicol. Chem., 25, 1275 (2006)

Applications 2-Bromonaphthalene

Applications 3’,4’-Dichloropropiophenone is used as a reagent in the preparation of antidepressant aryl-alkyl-piperidine derivatives. Also used in the synthesis of mGlu5 receptor negative allosteric modulators. Also in the genetic screening of compounds countering the growth of methylthioadenosine phosphorylase involved in cancer spread.
References Zheng, Y. et al.: Eur. J. Med. Chem., 54, 123 (2012); Kadariya, Y. et al.: J. Biomol. Scroon., 16, 44 (2011);

Applications 3-Chloromethyl-4-hydroxyacetophenone (cas# 24085-05-0) is a compound useful in organic synthesis.

Applications Filipin III is a cholesterol-binding, fluorescing antibiotic. Also, it is a pentaene macrolide produced by Streptomyces filipinensis, widely used for the detection and quantitation of cholesterol in biological membranes and as a tool for the diagnosis of Niemann-Pick type C disease;Polyene antibiotic, most extensively used tool for the specific detection of fluorescently labeled 3-β-hydroxysterols.
References Payero, T. D., et al.: Microb. Cell Fact., 14, 1-14 (2015); Stanislas, T., et al.: Methods Mol. Biol., 1209, 13-29 (2014)

Applications p-Nitrophenyl Acetate-13C,d3 (cas# 1794766-80-5) is a compound useful in organic synthesis.

Applications 8-Fluoro-5-isoquinolinecarboxylic Acid Methyl Ester is a useful synthetic compound.

Applications (Z,Z)-5,11-Eicosadienoic Acid Methyl Ester-d3 is the isotope labelled analog of (Z,Z)-5,11-Eicosadienoic Acid Methyl Ester (E476810); the methyl ester derivative of (Z,Z)-5,11-Eicosadienoic Acid (E476800) which is a biomarker for trophic transfer.
References Koussoroplis, A., et al.: Lipids, 43, 461 (2008); Nguyen, J., et al.: Drug Dev. Res., 51, 233 (2000)

Applications Bis(2-ethylhexyl) Azelate-d34 is the isotope labelled analog of Bis(2-ethylhexyl) Azelate (B433820); a compound used in the preparation of plasticizers.
References Nakajima, N., et al.: J. App. Polym. Sci., 95, 448 (2005); van Oosterhout, J., et al.: Polym., 44, 8081 (2003)

Applications 2'-O-Butyryladenosine 3',5'-cyclic phosphate DMAP is an intermediate in the synthesis of 2'-O-Monobutyryladenosine-3', 5'-cyclic Monophosphate (M525120), which is an impurity of Bucladesine Sodium Salt (B689320), a cell-permeable cAMP analogue that activates cAMP dependent protein kinase (PKA) or the cAMP/PKA signaling pathway.
References Yamauchi, J., et al.: J. Neurosci., 31, 12579 (2011); Ma, D., et al.: Mol. Pharmacol., 55, 50 (1999)

Applications Valeryl Chloride is used in the preparation of potent inhibitors of secretory phospholipase A2. Also used in the synthesis of small-molecule inhibitors of protein geranylgeranyltransferase Type I.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Castellano, S. et al.: J. Am. Chem. Soc., 129, 5843 (2007); Hagishita, S et al.: J. Med. Chem., 39, 3636 (1996);

Applications 4’-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-[1,1’-biphenyl]-4-carboxylic Acid is a building block for the preparation of vitronectin receptor antagonists.
References Neustadt, B.R., et. al.: Bioorg. Med. Chem. Lett., 8, 2395 (1998)

Stability Moisture Sensitive
Applications Pentathiodiphosphorus(V) Acid P,P′-Bis(pyridinium betaine) is an thionating agent used in synthetic chemistry.
References Bergman, J., et al.: J. Org. Chem., 76, 1546 (2011);

Applications Hydrazinecarboximidothioic Acid Methyl Ester Hydroiodide

Applications (2,6-difluorobenzoyl)urea (cas# 1342075-20-0) is a useful research chemical.

Applications 1,2-Dimethyl 4-nitrophthalate

Applications (3R,3'R)-N,N'-(ethane-1,2-diyl)bis(3-amino-4-(2,4,5-trifluorophenyl)butanamide) is a useful chemical reagent.

Applications Paroxetine intermediate.
References Oefner, C., et al.: Chem. Biol., 6, 127 (1999), Bower, J., et al.: Org. Biomol. Chem., 4, 1868 (2006)

Stability Freezer
Applications An intermediate used for the synthesis of 6-substituted purine ribosides.

Applications L-Methionine-d3-N-FMOC (S-methyl-d3) (CAS# 502692-58-2) is a useful isotopically labeled research compound.

Applications Urea-urethane Compound is a reaction product of 4,4'-sulfonylbis[benzenamine] and 2,4-TDI.

Applications 2,2'-Dimethoxy-1,1'-biphenyl is used in the synthesis of biphenyl scaffolds in the preparation of biphenyl-tetrathiafulvalene derivatives.
References Delogu, G. et al.: J. Org. Chem., 71, 9096 (2006);

Applications Dihydroorotate Acid Methyl Ester is a chemical reagent interacting with the dihydroorotate dehydrogenase enzyme in bovine liver mitochondria. This compound is suitable for dihydroorotate dehydrogenase (DHODH) related research.
References Hines, V. et al.: BIochem. 28, 1222 (1989);

Applications Azelaic Acid 2-Ethylhexyl Ester-d17 is labelled Azelaic Acid 2-Ethylhexyl Ester (A808180) which is an ester of Azelaic acid (A808140), an antiacne agent.
References Bladon, P.T., et al.: Br. J. Dermatol., 114, 493 (1986)

Applications 4,5-Diphenyl-1H-imidazole-2-propanoic Acid is an impurity of Oxaprozin (O845400), an anti-inflammatory drug. Oxaprozin was comparable to Aspirin (A687780).
References Whitehouse, M.W., et al.: Biochem. Pharmacol., 20, 2309 (1971); Janssen, F.W., et al.: Drug Metab. Dispos., 6, 465 (1978); Shriver, D.A., et al.: Toxicol. Appl. Pharmacol., 42, 75 (1977)

Applications An intermediate in synthesis of (R,R)-Formoterol.
References Murase, K., et al.: Chem. Pharm. Bull., 26, 1123 (1978), Trofast, J., et al.: Chirality, 3, 443 (1991), Anderson, G., et al.: Life Sci., 52, 2145 (1993),

Applications Naphthalene-1-d1 (CAS# 875-62-7) is a useful isotopically labeled research compound.

Applications 3-Benzyloxyacetophenone (cas# 34068-01-4) is a compound useful in organic synthesis.

Applications A useful building block for oligoribonucleotide synthesis.
References Zlatev, I., et al.: J. Med. Chem., 51, 5745 (2008),

Applications Hesperetin Benzyl Ether is an intermediate in the synthesis of (S)-Hesperetin (H289480), a flavanone found in citrus fruits.
References Tsujimoto, M., et al.: Biol. Pharm. Bull., 32, 671 (2009), Wang, H., et al.: J. Pharm. Biomed. Anal., 49, 1157 (2009)

Stability Hygroscopic
Applications 3-Iodothyronacetic Acid is a 3-Iodothyronamine metabolite that has functional effects in FRTL-5 thyroid cells.
References Agretti, P. et al.: J. Mol. Endocrinol., 47, 23 (2011);

Applications 6,6'-Dimethoxy-2,2'-binaphthalene, can be used for the synthesis of novel classes of non-steroidal substrate mimetics, as inhibitors of human CYP17. It is also an impurity of Nabumetone (N200500), a non-steroidal anti-inflammatory drug, acting as anti-inflammatory agent.
References Kumpulainen, H., et al.: J. Med. Chem., 49, 1207 (2006); Pinto-Bazurco, M. A. E., et al.: Bioorg. Med. Chem. Lett., 18, 267 (2008);

Applications 1-(adamantan-1-yl)-3-(prop-2-enoyl)urea (cas# 852399-58-7) is a useful research chemical.

Applications 2,2'-Dihydroxy-3,3',5,5'-tetrabromodiphenyl ether is a useful reactant and building block, and has been shown to display antimicrobial activity.
References Xin, Y.; et al.: Huaxue Yanjiu Yu Yingyong, 18, 1346 (2006).

Applications tert-Butyl 5-Iodovalerate is used as a reactant in the labeling of site-specific cell surface proteins with biophysical probes using biotin ligase.
References Chen, I., et al.: Nat. Methods, 2, 99 (2005);

Applications Intermediate in the preparation of Caffeic Acid metabolties.

Applications N-[[2'-(1H-Tetrazol-5-Yl)[1,1'-Biphenyl]-4-Yl]Methyl]Amine (cas# 147225-68-1) is a useful research chemical.

Applications 2’,3’,5’-Tri-O-acetyl Guanosine (cas# 6979-94-8) is a compound useful in organic synthesis.

Applications Ferulic acid ethyl ester is an ethyl ester derivative of Ferulic acid (F308900), which is used as an antioxidant and food preservative.
References Smart, M.G., et al.: Aust. J. Plant Physiol., 6, 485 (1979), Chen, C., et al.: J. Food Lipids, 2, 35,1995, Benzie, I., et al.: Anal. Biochem. 239, 70 (1996), Nardini, M., et al.: Food Chem., 79, 119 (2002), Lee, J., et al.: J. Agric. Food Chem., 52, 2647 (2004),

Applications Diethyl 2,2'-(1,3-Dithietane-2,4-diylidene)bis(cyanoacetate) is used in the synthesis of Olanzapine Thiohydroxymethylidene Impurity (O253795), which is a serotonin (5-HT2) and dopamine (D1/D2) receptor antagonist with anticholinergic activity.
References Moore, N.A., et al.: Curr. Opin Invest. Drugs, 2, 281 (1993), Baldwin, D.S. and Montgomery, S.A.: Int. Clin. Psychopharmacol., 10, 239 (1995), Tohen, M., et al.: Am. J. Psychiatry, 156, 702 (1999)

Applications 2,2'-Dibromobiphenyl
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications o-Cresol-3,4,5,6-d4,OD (CAS# 3647-00-5) is a useful isotopically labeled research compound.

Applications Isoguanosine Triacetate (cas# 173098-06-1) is a compound useful in organic synthesis.

Applications 5-Acetylsalicylic Acid Methyl Ester (cas# 16475-90-4) is a compound useful in organic synthesis.

Applications 5,6-Dihydro-4H-benzo[b]thieno[2,3-d]azepine-2-carboxylic Acid is an intermediate used to prepare benzothienoazepine compounds as respiratory syncytial virus (RSV) RNA polymerase inhibitors.
References Xiong, H., et al.: Bioorg. Med. Chem. Lett., 23, 6789 (2013)

Applications 2',4',6'-Trihydroxyacetophenone monohydrate (cas# 249278-28-2) is a useful research chemical.

Applications N-Methyl-N-1-naphthalenylacetamide is a useful compound for organic synthesis.

Applications 4-tert-Butyl-2-nitrophenol (cas# 3279-07-0) is a useful research chemical.

Applications N,N'-Diisopropylthiourea is a reagent for the improved synthesis of cefathiamidine. Studies on the chemical nature of the thyroid inhibiting actions of compounds. Design and testing of antithyroid agents with decreased antioxidant activity.
References Wang, H., et al.: Zhongguo Xiandai Yingyong Yaoxue, 27, 126 (2010); Astwood, E. B., et al.: Endocrinology, 37, 456 (1945); Abou-Shaaban, R. R. A., et al.: Pharm. Res., 13, 129 (1996)

Applications 2,6-Dimethylnaphthalene-d12 (CAS# 350820-12-1) is a useful isotopically labeled research compound.

Applications Used in the preparation of cinnamamide derivative as 5α-reductase inhibitors.
References Mai, A., et al.: J. Med. Chem., et al.: 49, 6046 (2006),

Applications Isotope labelled N-(1-Naphthyl)phthalamic Acid is an auxin-transport inhibitor in plants resulting in the attenuation of root growth through decreasing the cell production rate.
References Rahman, A. et al.: Plant, J., 50, 514 (2007); Ott, K. et al.: Phytochem., 62, 971 (2003);

Applications N-[(2-Methoxyphenyl)methyl]-N,α,4-trimethylbenzeneethanamine is a new psychoactive substance that is a highly potent hallucinogen.
References Caspar, A. T., et al.: Talanta, 188, 111 (2018); Westphal, F., et al.: Drug Test. Anal., 8, 910 (2016);

Applications 4-Chlorobiphenyl-2',3',4',5',6'-d5 (CAS# 51624-37-4) is a useful isotopically labeled research compound.

Applications 4-Nitrophenyl 1H-Indole-3-acetic Acid Ester is an intermediate used in the synthesis of Indole-3-acetyl-L-aspartic Acid (I577370), which is an indole-3-acetyl-amino acid conjugate involved in regulatory mechanisms for the control of auxin activity during physiological and pathophysiological responses.
References Ostrowski, M., et al.: J Plant Physiol, 191, 63-72 (2016)

Applications 3',4'-Dimethoxyacetophenone-d3 (methyl-d3) (CAS# 350818-54-1) is a useful isotopically labeled research compound.