Standard farmaceutici

Applications Glutaric Acid derivative
References Higashi, K., et al.: Chem. Pharm. Bull., 40, 1042 (1992), Wilde, J., et al.: Eur. J. Biochem., 221, 463 (1994),

Applications Indole-2,4,5,6,7-d5-3-acetic Acid is an isotopic analog of Indoleacetic Acid (I577340) which is the most common and naturally occuring plant hormone in the auxin class of hormones. It effects cell elongation, cell division as well as plant growth and development.

Applications N-Ethyl-N-pentyl-β-alanine is a compound useful in organic synthesis.

Applications p-Aminosulfonyldihydrocinnamic acid

Stability Moisture Sensitive
Applications 4,4’-Oxydibenzenesulfonyl Chloride is useful as an intermediate for blowing agents for rubber or resin.
References Sato, N., et al.: Jpn. Kokai Tokkyo Koho, JP 60156662 A 19850816 (1985); Crowley, R.P., et al.: U.S. US 3829500 A 19740813 (1974)

Applications N-Methyl-N-(1-methylbutyl)-β-alanine is a compound useful in organic synthesis.

Applications 2-Chloro-4-nitrophenol is used as a sole source of carbon and nitrogen by Cupriavidus strain a3.
References Tiwari, J., et al.: Bioresour. Technol., 223, 184-191 (2017)

Applications 4'-Fluorovalerophenone (CAS:709-24-0) is a useful research compound.

Applications (2-​Deoxy-​D-​erythro-​pentofuranosyl)​-urea is used as a reactant in the preparation of 2'-deoxyribosylurea by thymidine oxidation.
References Dubey, I., et al.: Nucleos. Nucleot. Nucl., 20, 1463 (2001)

Applications 3-Bromo-4-nitrophenol (cas# 5470-65-5) is a compound useful in organic synthesis.

Applications 2-Amino-5-bromopyrazine-3-carboxylic Acid Methyl Ester is used as the starting material in the preparation of pyrazine derivatives that are AxI and c-Met receptor enzyme inhibitors. These inhibitors are useful in the treatment of tumors. 2-Amino-5-bromopyrazine-3-carboxylic Acid Methyl Ester is also used in the preparation of potent and selective inhibitors of ataxia telangiectasia mutated and Rad3 related (ATR) protein kinase as potential anticancer agents.
References Rushton, L.; et al.: PCT Int. Appl. 119 pp. Patent 2009 CODEN:PIXXD2; Charrier, J-D.; et al.: J. Med. Chem, 54, 2320 (2011)

Applications L-Methionine methyl ester is a protected form of L-Methionine (M260440). L-Methionine is an essential amino acid that is obtained from our diet. L-Methionine can be found in grain legumes (such as lentils), and poultry. L-Methionine’s main function is to act as the primary “Start” sequence on mRNA so that the ribosomes can start translating the mRNA into proteins.
References Forbes, J. & Shariatmadari, F.: World. Poul. Sci. J., 50, 7 (24); Kozak, M.: J. Cell. Biol., 108, 229 (1989); Müntz, K., et al.: Food/Nahrung, 42, 125 (1998); Wright, L., et al.: Amer. J. Physiol., 149, 130 (1947)

Applications 3,3'-BIS(TRIFLUOROMETHYL)BENZOPHENONE (cas# 1868-00-4) is a useful research chemical.

Applications Gallacetophenone 3’,4’-Dimethyl ether is a phenolic compound with potential 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging activity.
References Zheng, C.-D. et al.: Nat. Prod. Comm., 5, 1759 (2010);

Applications 4,5,6,7-Tetrahydro-7-oxo-benzo[b]thiophene-4-carboxylic Acid methyl Ester is a useful synthetic intermediate.

Applications A metabolite of Nabumetone.
References Nobilis, M., et al.: J., Pharm., Biomed., Anal., 32, 641 (2003),

Stability Moisture Sensitive
Applications 2,3-Naphthalic anhydride is used as a reagent to synthesize analogues of Thalidomide (T338850), an inhibitor of tumour necrosis factor that was once abandoned because it caused birth defects, but is currently used as an inhibitor of angiogenesis in patients with multiple myeloma.
References D’Amato, R., et al.: Proc. Nat. Acad. Sci., 91, 4082 (1994); Ehrenpreis, E., et al.: Gastroenterology, 117, 1271 (1999); Parma, T., et al.: Nat. Med., 5, 582 (1999); Singhal, S., et al.: New Engl. J. Med., 341, 1565 (1999)

Applications 6-Nitropyrido[2,3-d]pyrimidin-4(3H)-one is a useful research chemical for organic synthesis and other chemical processes.

Applications 1,3-Dicyclohexyl-2-phenyl-pseudourea is an intermediate in the synthesis of [R-(R*,R*)]-(1,2-Dihydroxypropyl)phosphonic Acid (D454455) which is a Fosfomycin (F727500) impurity. Fosfomycin is an antibiotic that exerts a broad spectrum of antibacterial activity. P-[(1R,2R)-1,2-Dihydroxypropyl]-phosphonic Acid is an intermediate in the synthesis of [2-[2-Amino-3-hydroxy-2-(hydroxymethyl)propoxy]-1-hydroxypropyl]phosphonic Acid (A611565), another Fosfomycin (F727500) impurity.
References McGrath, J.W., et al.: Org. Biomolec. Chem., 7, 9 (1944); Goto, M., et al.: Antimicrob. Agents Chemother., 20, 393 (1981);

Applications An impurity of Docetaxel (D494420).
References Zamir, L., et al.: Tetrahedron Lett., 33, 5173 (1992), Gueritte-Voegelein, F., et al.: J. Med. Chem., 34, 992 (1993), Volk, K., et al.: J. Chromatogr., 696, 99 (1997),

Applications (S)-(4-Nitrophenyl)oxirane is used as a reagent in the enantioconvergent synthesis of the β-blocker (R)-Nifenalol which is based on a combined chemoenzymic approach.
References Paedragosa-Moreau, S., et al.: Tetrahedron, 53, 9707 (1997)

Stability Unstable in Solution
Applications β-Ketoglutaric Acid is used in the synthesis of benzodiazepine derivatives. Also used in the synthesis of orally available hepatitis C virus polymerase inhibitors.
References Jung, D. et al.: Synth. Comm., 29, 1941 (1999); Li, H. et al.: J. Med. Chem., 52, 1255 (2009);

Applications Cholesterol-3-d1 (CAS# 51467-57-3) is a useful isotopically labeled research compound.

Applications Norcamphor is a building block that is used in organic synthesis. Norcamphor has been used as a reactant in the synthesis of cardo-polymers with high gas permeabilities.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Carta, M., et. al.: Polymer Chem., 5, 5255 (2014)

Applications A potential metabolite of Exemestane (E957000).
References Buzzetti, F., et al.: Steroids, 58, 527 (1993),

Applications o-Nitrophenylsulfonyl Chloride is used in the synthesis of renin inhibitors and also anticonvulsants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Harish, K. et al.: Lett. Drug Des. Disc., 10, 783 (2013); Michida, M. et al.: Org. Proc. Res. Dev., 17, 1430 (2013);

Applications Indazole-3-carboxylic Acid Methyl Ester has potential as application of N-benzoylindazole derivatives and analogues as inhibitors of human neutrophil elastase. Also used in the preparation of indazole-pyridine based protain kinase/Akt inhibitors.
References Crocetti, L. et al.: Bioorg, Med. Chem., 19, 4460 (2011); Woods, K. et al.: Bioorg. med. Chem., 14, 6832 (2006);

Stability Hygroscopic
Applications 6-Amidino-2-naphthol Methanesulfonate is a useful N-terminal derivatization reagent for improving peptide fragmentation.
References Miyashita, M., et al.: Rapid Commun. Mass Spectrom., 25, 1130 (2011)

Applications Hydroxy Acetildenafil-d4 is the isotope labelled analog of Hydroxy Acetildenafil, which is a Sildenafil (S435000) analog, enhances male sexual function.
References Hou, P., et al.: Food Addit. Contam., 23, 870 (2006), Reepmeyer, J., et al.: J. Pharm. Biomed. Anal., 44, 887 (2007), Park, H., et al.: Food Addit. Contam., 24, 122 (2007),

Applications 2',6'-Dihydroxyacetophenone (cas# 699-83-2) is a compound useful in organic synthesis.

Applications 3-Chlorosalicylic Acid (cas# 1829-32-9) is a compound useful in organic synthesis.
References Shackelford, J.M.: J.O.C., 26, 4908 (1961)

Applications 5-Bromovaleric Acid used in the synthesis of inhibitors for aminoglycoside resistant bacteria. Also used in the preparation of sequence specific base pair mimics as topoisomerase IB inhibitors.
References Vong, K. et al.: ACS Chem. Biol., 7, 470 (2012); Vekhoff, P. et al.: Biochem., 52, 43 (2012);

Applications 4-Benzyloxyacetophenone is used in preparation of inhibitors of various proteins such as hepatitis C virus polymerase, glucosylceramide synthase and protein tyrosine phosphatase 1B.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Deng, Y., et al.: Bioorg. Med. Chem. Lett., 19, 5363 (2009); Lee, L., et al.: J. Biol. Chem., 274, 14662 (2009); Liu, Z., et al.: Bioorg. Med. Chem. Lett., 21, 3755 (2011)

Applications An intermediate in the production of Guanidinoacetic Acid
References Kennelly, P., et al.: J. Mol. Biol., 145, 583 (1981),

Applications N,N'-Diethyl-N'-(4-nitrophenyl)-N-phenylurea is a nitro derivative of the propellent stabilizer and burn rate moderator 1,3-Diethyl-1,3-diphenylurea (D472880).
References Betz, R., et al.: Acta. Crystallogr. Sect. E. Struct. Rep., 1, 827 (2011); Perez, J.J., et al.: Anal. Chem., 85, 296 (2013);

Applications (S)-(-)-1-(2-Naphthyl)ethanol is a useful biochemical for proteomics research.

Stability Hygrscopic
Applications 2,2'-Biquinoline-4,4-dicarboxylic acid disodium salt

Applications 6,7-Dihydroxyflavone (cas# 38183-04-9) is a useful research chemical.

Applications A volatile lactone found in fruits giving ripe produce their aroma.
References Tavori, H., et al.: Bioorg. Med. Chem., 16, 7504 (2008), Pandit, S., et al.: J. Sci. Food Agric., 89, 2071 (2009), Xiang, D., et al.: Biochem., 48, 2237 (2009), Pandit, S., et al.: Food Chem., 114, 363 (2009),

Applications Acetophenone-d3 is an isotopic analog of acetophenone (A164015), a reagent used in the production of fragrances and resin polymers. This compound is a contaminant of emerging concern (CECs)
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Perez, D., et al.; Bioorg. Med. Chem., 17, 6914 (2009), Giet, J., et al.: J. Agric. Food Chem., 57, 6787 (2009), Dimoula, K., et al.: Biotechnol. J., 4, 712 (2009),

Applications 1-BROMOANTHRACENE (cas# 7397-92-4) is a useful research chemical.

Applications 3-Bromo-2-(trifluoromethyl)benzoic Acid Methyl Ester is a useful synthetic intermediate.

Applications rac 4-Hydroxy-7-methoxy-4-(4-benzyloxyphenyl)-1,2,3,4-tetrahydronaphthalene (cas# 1286878-19-0) is a compound useful in organic synthesis.

Applications 2,​4-​Hexadecadienoic acid has been used as a compound for the study of Langmuir’s monolayer behaviour in an air/water interface.
References Lee, K.J., et al.: Macromolecular Reports, A30, 101-9 (1993)

Applications L-Isolecucine 7-Amido-4-methylcoumarin Trifluoroacetate Salt is an enzyme substrate. It can be used as analytical reagent use and in biological study of detection of yeasts and/or molds in a food sample using aminopeptidase substrates containing a fluorescent marker.
References Chen, C., et al.: PCT Int. Appl., WO 9827223 A1 19980625 (1998)

Applications 3’,4’-Dichloropropiophenone is used as a reagent in the preparation of antidepressant aryl-alkyl-piperidine derivatives. Also used in the synthesis of mGlu5 receptor negative allosteric modulators. Also in the genetic screening of compounds countering the growth of methylthioadenosine phosphorylase involved in cancer spread.
References Zheng, Y. et al.: Eur. J. Med. Chem., 54, 123 (2012); Kadariya, Y. et al.: J. Biomol. Scroon., 16, 44 (2011);

Applications Bis(2-ethylhexyl) Azelate-d34 is the isotope labelled analog of Bis(2-ethylhexyl) Azelate (B433820); a compound used in the preparation of plasticizers.
References Nakajima, N., et al.: J. App. Polym. Sci., 95, 448 (2005); van Oosterhout, J., et al.: Polym., 44, 8081 (2003)

Applications (±)-Fluoxetine-d5 Oxalate (phenyl-d5) (CAS# 1219804-82-6) is a useful isotopically labeled research compound.

Applications 2-(3-Nitrophenyl)ethanamine (cas# 83304-13-6) is a useful research chemical.

Applications Hydrohchloride Salt of α-Aminoacetophenone, used in the preparation og pseudopeptidic inhibitors of human sirtuins1-3. This action effectually displays antiproliferative protperties in cancer cells. Also used in the preparation of dual δ/μopiod receptor agonists in th
References Mellini, P. et al.: J. Med. Chem., 56, 6681 (2013); Breslin, H. et al.: Bioorg. Med. Chem. Lett., 22, 4869 (2013);

Stability Freezer
Applications An intermediate used for the synthesis of 6-substituted purine ribosides.

Applications L-Methionine-d3-N-FMOC (S-methyl-d3) (CAS# 502692-58-2) is a useful isotopically labeled research compound.

Applications Dihydroorotate Acid Methyl Ester is a chemical reagent interacting with the dihydroorotate dehydrogenase enzyme in bovine liver mitochondria. This compound is suitable for dihydroorotate dehydrogenase (DHODH) related research.
References Hines, V. et al.: BIochem. 28, 1222 (1989);

Applications An intermediate in synthesis of (R,R)-Formoterol.
References Murase, K., et al.: Chem. Pharm. Bull., 26, 1123 (1978), Trofast, J., et al.: Chirality, 3, 443 (1991), Anderson, G., et al.: Life Sci., 52, 2145 (1993),

Applications Naphthalene-1-d1 (CAS# 875-62-7) is a useful isotopically labeled research compound.

Applications A useful building block for oligoribonucleotide synthesis.
References Zlatev, I., et al.: J. Med. Chem., 51, 5745 (2008),