Standard farmaceutici

Stability Hygroscopic
Applications A main Levomepromazine metabolite
References Hals, P., et al.: Human Toxicol., 3, 497 (1984), Cutroneo, P., et al.: J. Pharm. Biomed. Anal., 41, 333 (2006),

Applications Aluminum Glycinate is an antacid which is used in the treatment of peptic ulceration. It is used in the development of a transdermal hydrogel patch for ferulic acid to treat skin damage induced by UV radiation.
References Rice, M., et al.: Am. J. Gastroenterol., 25, 74 (1956); Bai, J., et al.: Pak. J. Pharm Sci., 27, 369 (2014);

Applications The R-enantiomer of Baclofen (B108000) metabolite.

Applications Labelled 1-Naphthol (N367990). Used in the manufacturing of dyes, intermediates, synthetic perfumes.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Metabolite from phenanthrene degradation.
References Pinyakong, O. et al.: FEMS Microbiol. Lett. 191, 115 (2000)

Applications Calcium Chloride Dihydrate is used in the preparation of bisphosphonates used in attacking cancer cells.
References Liu, D. et al.: Chem. Comm., 48, 2668 (2012);

Applications Fmoc-3-(2-naphthyl)-D-alanine is an intermediate used in the preparation of phosphoserine-containing tetrapeptides with hydrophobic N-terminal acyl groups as inhibitors of the BRCA1 protein.
References Yuan, Z., et al.: Med. Chem. Lett., 2, 767 (2011); Liu, T., et al.: ACS. Comb. Sci., 13, 537 (2011);

Applications N-(1-Ethylpropyl)-N-methyl-β-alanine is a compound useful in organic synthesis.

Stability Moisture Sensitive
Applications 5-Acetamidonaphthalene-1-sulfonyl Chloride (cas# 52218-37-8) is a compound useful in organic synthesis.
References Bradbury, R., et al.: J. Med. Chem., 40, 996 (1997),

Applications Cholesterol-d6 has been used in safe procedures to measure the percentage of cholesterol absorption, based on that of D. B. Zilversmit (1972), by using Cholesterol-d6 as a stable nonradioactive isotopic tracer of cholesterol that was administered orally into normal individuals to facilitate clinical investigation.
References Bosner, Matthew S., Journal of Lipid Research, 34, 1047-53, (1993)

Applications 2-Cyano-2-(hydroxyimino)acetic Acid is a degradation product of Cymoxanil (C988995), which is a fungicide applied as a seed treatment or as a foliar application to the plants to control late blight. It is an effective ligand for Cu2+ and Ni2+ ions over a broad pH range and useful reagent for synthesizing chelating agents.
References Morrica, P., et al.: J. Agric. Food Chem. 52, 99 (2004); Dhingani, J. C., et al.: J. Pure. App. Microbiol., 6, 1683 (2012); Bakirici, G.T., et al.: Food. Chem., 135, 1901 (2012); Sliva, T. Y., et al.: Dalton Trans. 11, 1863 (1998)

Applications N-(Valeryl-d9) Fentanyl is deuterium labeled N-Valeryl Fentanyl (V091520). N-Valeryl Fentanyl is an impurity of Furanylfentanyl (F864085), which is an opiod analgesic agent and an analog of Fentanyl (F275000). In addition, N-Valeryl Fentanyl can be used to develop fentanyl-conjugated vaccines by utilizing a protein–drug conjugate that generates an in vivo immunoantagonist, which can minimize the concentration of a specific drug at the sites of action.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bremer, P. T., et al.: Angew. Chem. Int. Ed. 55, 3772 (2016); Zernig, G., et al.: Life Sci., 57, 2113 (1995), Bot, G., et al.: J. Pharmacol. Exper. Therap., 285, 1207 (1998)

Applications Testosterone (T155000) derivative. Intermediate in the preparation of Epostane (E588850).

Applications 4'-[(4,5-Dimethyl-3-isoxazolyl)sulfamoyl]acetanilide is an renal metabolite of Sulfatroxazole (S699265), is an component present in various veterinary drugs.
References Nouws, J. F. M., et al.: J. Vet. Pharmacol. Ther., 12, 50 (1989);

Applications (R,E)-2-Acetamido-3-((phenyldiazenyl)thio)propanoic-13C6 Acid is labelled N-Acetyl-S-phenyl-L-cysteine (P335600), which is an important metabolite of Benzene.
References Muller, G., et al.: Anal. Hazard. Subst. Biol. Mater., 5, 143 (1997)

Applications 2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinoline]-1',3'-dione (cas# 31267-07-9) is a useful research chemical.

Applications 4-​Hydroxy-​benzenebutanoic Acid Methyl Ester is an intermediate in synthesizing Arbutamine (A766300). It is a cardiac stimulant. Arbutamine stimulates adrenergic receptors.
References Sinusas, A., et al.: J. Nucl. Med., 35, 664 (1994); Sansoy, V., et al.: Circulation, 92, 994 (1995); Elhendy, A., et al.: Eur. J. Nucl. Med., 23, 1354 (1996);

Applications 2,6-Dimethyl-3,5-dicarboxy-4-(2-nitrophenyl)-1,4-dihydropyridine is used as a reactant in the preparation of hydroxyindolecarboxylate and hydroxycarbolinecarboxylate from nifedipine analogous cyanoethyl ester.
References Gorlitzer, K., et al.: Pharmazie, 55, 35 (2000)

Stability Light Sensitive, Moisture Sensitive, Temperature Sensitive
Applications A major metabolite of Irinotecan.
References Canal, P., et al.: J. Clin. Oncol., 14, 2688 (1996), Haaz, M., et al.: Cancer Res., 58, 468 (1998), Kehrer, D., et al.: Clin. Cancer Res., 6, 3451 (2000), Hanioka, N., et al.: Xenobiotica, 31, 687 (2001), Satoh, T., et al.: Drug Metab. Dispos., 30, 488 (2002),

Applications 2’,3’-Isopropylidene Adenosine (cas# 362-75-4) is a compound useful in organic synthesis.

Applications o-Cresol-3,4,5,6-d4,OD (CAS# 3647-00-5) is a useful isotopically labeled research compound.

Applications Tetramethyl-d12-urea (CAS# 51219-89-7) is a useful isotopically labeled research compound.

Applications 5-Bromo-2-nitrophenol is a halonitrophenol with antifungal activity.
References Gershon, H., et al.: Monatshefte fuer Chemie, 126, 1161 (1995)

Applications γ-Valerolactone-d3 is the isotope labelled analog of γ-Valerolactone. γ-Valerolactone is a naturally occurring chemical found in fruits and is frequently used as a food additive. It can be converted to liquid alkenes which can be used as transportation fuels.
References Horvath, I.T., et al.: Green Chem., 10, 238 (2008); Bond, J.Q., et al.: Science, 327, 1110 (2010)

Applications 2-Amino-3’-hydroxy-acetophenone Hydrochloride is a reactant in the synthesis of TRPM8 modulators.
References PCT Int. Appl. (2014), WO 2014130582 A2 20140828;

Applications 2,2'-Dibromobiphenyl
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications N3-Methanethiosulfonylethyl Lumiflavin is a derivative of the Lumiflaviin (L473900), a toxic photolysis product of vitamin B2.

Applications Testosterone-2,2,4,6,6-d5 Heptanoate is a useful isotopically labeled compound of Testosterone Enanthate (T155080)

Applications tert-Butyl 5-Iodovalerate is used as a reactant in the labeling of site-specific cell surface proteins with biophysical probes using biotin ligase.
References Chen, I., et al.: Nat. Methods, 2, 99 (2005);

Applications 8-Acetyl-6,10,11-trihydroxy-1-methoxy-5,12-naphthacenedione is an intermediate in the synthesis of 7,8,9,10-Dehydro Doxorubicinone (D229580).

Applications Isotope labelled (R)-(-)-2-Oxothiazolidine-4-carboxylic Acid (O870505), a precursor to glutathione (GSH) which is an important antioxidant in plants, animals and fungi.
References Meister, A., et al,: J. Am. Coll. Nutr., 5, 137 (1986);

Applications Testosterone Hexanoate-d11 is the isotopic analog of Testosterone Hexanoate. Testosterone Hexanoate is a metabolite of testosterone(T155000), which is used in analytical studies to determine the use of anabolic steroid esters and related compounds in equine hair sample though ultra high performance liquid chromatography-tandem mass spectrometry.
References Gray, B.P., et al.: Analtica Chemica Acta, 787, 163 (2013); McKinney, A., et al.: Bioanalysis 1, 785 (2009)

Applications 1-Aminonaphthalene-d9 (CAS# 78832-56-1) is a useful isotopically labeled research compound.

Applications ESCULIN SESQUIHYDRATE (cas# 66778-17-4) is a useful research chemical.

Applications 2-[(4-Nitrophenyl)thio]-acetic Acid Octyl Ester is an intermediate in the synthesis of labelled Sodium Trifluoroacetate which is a compound used as an intermediate for various pharmaceutical, agricultural and chemical applications.

Applications (±)-Betaxolol-d7 HCl (iso-propyl-d7) (CAS# 1219802-92-2) is a useful isotopically labeled research compound.

Applications Isovaleryl L-Carnitine Chloride is used to prepare carnitine benzyl esters as neuroprotectant prodrugs.
References Gong, X., et al.: J. Chem. Res., 6, 327 (2008)

Applications 3-Chloro-6-(chloromethyl)benzene-1,2,4,5-d4 is an isotope-labeled analog of 4-Chlorobenzyl Chloride (C364730), which is a benzylchloride derivative used in the preparation of various biologically active compounds such as bronchodilators and antibacterial agents.
References Adams, M. et al.: Synth. Comm., 29, 2419 (1999); Foroumadi, A. et al.: Arch. Pharm. Res., 30, 138 (2007);

Applications 4-Androsten-11b,17b-diol-3-one-2,2,4,6,6-d5 is a useful isotopically labeled compound of 11β-Hydroxytestosterone (H956785)

Applications (+)-β-Eudesmol-7,7,8a,8’8’-D5 is an isotope labeled analog of (+)-β-Eudesmol (E938600), which is a sesquiterpenoid molecule that affects the central nervous system (CNS). It is known to induce neurite outgrowth. Antiangiogenic activity.
References Obara, Y. et al.: J. Pharmacol. Exp . Ther., 30, 803 (2011); Tsuneki, H. et al.: Eur. J. Pharmacol., 512, 105 (2005);

Applications Hesperetin Benzyl Ether is an intermediate in the synthesis of (S)-Hesperetin (H289480), a flavanone found in citrus fruits.
References Tsujimoto, M., et al.: Biol. Pharm. Bull., 32, 671 (2009), Wang, H., et al.: J. Pharm. Biomed. Anal., 49, 1157 (2009)

Applications (±)-Carisoprodol-d7 (iso-propyl-d7) (CAS# 1218911-01-3) is a useful isotopically labeled research compound. As a deuterated drug analog, this compound can be used for inter-patient variability.
References Gant, T., et.al., U.S. Pat. Appl. Publ., 28,(2010);

Applications 6-Methoxy-2-naphthylboronic Acid, is used for the synthesis of Nabumetone (N200500), and its impurities , such as 6,6'-Dimethoxy-2,2'-binaphthalene (D461365).
References Kumpulainen, H., et al.: J. Med. Chem., 49, 1207 (2006); Pinto-Bazurco, M. A. E., et al.: Bioorg. Med. Chem. Lett., 18, 267 (2008);

Applications 3-Benzyloxyacetophenone (cas# 34068-01-4) is a compound useful in organic synthesis.

Applications 4-Aminobenzoic-​2,​3,​5,​6-​d4 Acid Methyl Ester is an intermediate in the synthesis of DMABA-d4 NHS Ester (D678402), which is a labelled DMABA NHS ester (D678400). DMABA NHS ester is a reagent that reacts with the primary amine group of PE lipids. DMABA NHS ester has been used in combination with DMABA NHS ester-d4, -d6, and -d10 to study relative changes in PE lipid abundance before and after radical oxidation.
References Wester, H., et al.: Nucl. Med. Bio., 23, 365 (1996), Frees, D., et al.: Mol. Microbiol., 48, 1565 (2003), Michel, A., et al.: J. Bacteriol., 188, 5783 (2006), Voelker, T., et al.: Bioorg. Med. Chem., 17, 2047 (2009),

Applications Butyric acid derivative. Displays some anti-inflammatory activity.

Applications Cresyl Diphenyl Phosphate-d7 Isomer 3 is the deuterated form of Cresyl Diphenyl Phosphate (C783015), which is a phosphorus flame retardant additive.
References van der Veen., et al.: Chemosphere, 88, 1119 (2012);

Applications 4,5-Diphenyl-1H-imidazole-2-propanoic Acid is an impurity of Oxaprozin (O845400), an anti-inflammatory drug. Oxaprozin was comparable to Aspirin (A687780).
References Whitehouse, M.W., et al.: Biochem. Pharmacol., 20, 2309 (1971); Janssen, F.W., et al.: Drug Metab. Dispos., 6, 465 (1978); Shriver, D.A., et al.: Toxicol. Appl. Pharmacol., 42, 75 (1977)

Applications (4R,5R)-2,2-Dimethyl-α,α,α',α'-tetra-2-naphthalenyl-1,3-dioxolane-4,5-dimethanol, is a privileged ligand analogue of TADDOLs. It can be broadly used in asymmetric synthesis. It is also shown that the titanium TADDOLate catalysts have broad application towards carbonyl addition and cycloaddition.
References Seebach, D., et al.: Ange. Chem. Inter. Ed., 40, 92, (20010;

Applications (±)-Carvedilol-d4 (ethyl-d4) (CAS# 1133705-56-2) is a useful isotopically labeled research compound.

Applications 5-Aminomethyl-salicylic Acid Methyl Ester Hydrochloride (cas# 90610-24-5) is a useful research chemical.

Applications 4-(chloromethyl)-2-(4-nitrophenyl)-1,3-oxazole (cas# 39867-96-4) is a useful research chemical.

Applications Labelled Dapoxetine (D185700). Selective serotonin reuptake inhibitor (SSRI).
References Feret, B., et al.: Formulary, 40, 227 (2005),

Applications 2-Aminopyrazine-5-carboxylic Acid Methyl Ester (cas# 13924-94-2) is a compound useful in organic synthesis.

Applications (S)-(-)-Ofloxacin-d3 (N-methyl-d3) (CAS# 2208780-63-4) is a useful isotopically labeled research compound.

Applications Hydrocinnamic-alpha,alpha-d2 Acid (CAS# 19136-97-1) is a useful isotopically labeled research compound.

Applications 2,2'-Dimethoxy-1,1'-biphenyl is used in the synthesis of biphenyl scaffolds in the preparation of biphenyl-tetrathiafulvalene derivatives.
References Delogu, G. et al.: J. Org. Chem., 71, 9096 (2006);

Applications N-Desmethyl analog of Rosuvastatin Lactone (R700550); an intermediate in the production of Rosuvastatin (R700500) derivatives.

Applications An impurity of the analgesic Ketorolac (K235650).

Applications 5-(4’-Benzyloxyphenyl)-2-oxazolidone (cas# 88693-98-5) is a compound useful in organic synthesis.

Applications (cas# 53188-20-8) is a useful research chemical.