Glicoscienza

<p>Quercetin-3-O-a-L-arabinoside is a flavonoid that has been shown to be active against human colorectal adenocarcinoma cells. Quercetin 3-O-a-L-arabinoside inhibits the proliferation of hl60 cells by inducing apoptosis and inhibiting protein synthesis. The biological properties of quercetin 3-O-a-L-arabinoside are not well understood, but it may work as an antioxidant due to its ability to scavenge free radicals. Quercetin 3-O-a-L-arabinoside has also been found to have antimicrobial activity against bacteria, fungi, and viruses. Quercetin 3 O a L arabinoside is able to inhibit the growth of various strains of Mycobacterium tuberculosis, including drug resistant strains. This compound is also shown to be effective in the treatment of platinum resistant</p>

<p>1,2,3,6-Tetra-O-acetyl-4-O-[2,3,6-tri-O-acetyl-4-O-(2,3,4,6 tetra-O-acetyl bDglucopyranosyl)-bDglucopyra nosyl]-bDthioglucopyranose (1) is a sugar with the chemical formula C36H62N8O24. It was first synthesized by the group of L. W. F. Heckel in 1956 and its structure was elucidated by X. Miettinen in 1957. 1 is a complex carbohydrate with a glycosidic linkage to 4 as well as an acetate ester at position 6. The compound has been modified with methyl groups at positions 2 and 3 to form 1,2,3,6 tetra O acetyl 4 O methyl 2 O methyl 3 O methyl 6 O eth</p>

1-Deoxy-1-nitro-D-mannitol is an inorganic molecule that has a proton and a voltammetry. It is used to monitor the transport of d-arabinose across the blood vessels in the femoral vein. This compound is synthesized by the reaction of sodium nitrite with mannitol in the presence of hydrochloric acid. It can be detected using optical techniques, such as UV/VIS spectroscopy, fluorescence spectroscopy, and absorption spectroscopy. 1-Deoxy-1-nitro-D-mannitol has been shown to have a cotton effect on neurotransmitters in the frontoparietal cortex.

2,3,4,6-Tetra-O-benzyl-1-deoxynojirimycin hydrochloric acid salt is a synthetic monosaccharide. It was originally synthesized by the methylation of a native oligosaccharide before being subjected to click chemistry. The resulting product is a complex carbohydrate with an aromatic ring in place of the sugar alcohol moiety. 2,3,4,6-Tetra-O-benzyl-1-deoxynojirimycin hydrochloric acid salt has CAS number 72983-76-7 and is soluble in water. This product is also available as a custom synthesis service and can be modified to meet your needs.

<p>This is a custom synthesis of (5R, 6R, 7R, 8S) -5, 7-dihydroxy-8- (hydroxymethyl) -1-azabicyclo[4.2.0]octan-2-one. This compound has been fluorinated and methylated and has a monosaccharide modification.</p>

<p>2,4-Dihydroxy-2-hydromethylbutanoic acid-1,4-lactone is a hydroxy anion that can be synthesized by the lactonization of 2,4-dihydroxybutanoic acid. The compound has been used to produce polymeric adsorbents for chromatographic purposes.</p>

<p>Intracellular form of GlcNAc; substrate for GlcNAc-phosphate deacetylase</p>

Methyl 2,4-di-O-methyl-α-D-glucopyranoside is a selectively protected glucose glycoside

<p>Man-9 N-glycan is a glycoprotein that is found on the surface of many viruses. It has an oligosaccharide structure, which consists of a mannose and a glucose molecule linked by an alpha-1,3-glycosidic bond. The Man-9 N-glycan can be found in human serum and is involved in lectin binding to cells. It also has antiviral activity and may be used as a model system for studying glycosidic bonds. This glycan can be broken down into smaller components by methyl glycosides or titration calorimetry, which is a technique for determining the molecular weight of substances. The Man-9 N-Glycan binds to toll-like receptor 2 (TLR2) on the surface of human cells, which activates an antibody response.</p>

<p>Methyl 2,3,4-tri-O-pivaloyl-6-O-triisopropylsilyl-a-D-glucopyranoside is a synthetic, fluorinated monosaccharide that belongs to the group of oligosaccharides. It is used in the synthesis of complex carbohydrates. Methyl 2,3,4-tri-O-pivaloyl-6-O-triisopropylsilyl-a-D-glucopyranoside is a custom synthesis and can be modified with methylation or click chemistry. Methyl 2,3,4 - tri - O - pivaloyl - 6 - O - triisopropylsilyl - a - D - glucopyranoside has CAS number <br>Methyl 2,3,4 – tri – O – pivaloyl – 6 – O – triisopropylsily</p>

2-Deoxy-2-fluoro-3,4:5,6-di-O-isopropylidene-L-idonic acid methyl ester is a synthetic compound that has been used as an intermediate in the synthesis of saccharides and oligosaccharides. It can also be used to modify carbohydrate structures. 2DFFDLIEME is a white crystalline solid with a melting point of 190°C. This product is soluble in water and ethanol.

<p>Click reagent for metabolic labeling of GlcNAc</p>

<p>Inhibitor of alpha-glucosidase</p>

<p>The blood group B type III/IV linear trisaccharide is a synthetic oligosaccharide. The methylation of the saccharide and click modification of the polysaccharide molecule allow for fast, efficient synthesis. This product has been custom synthesized to be free of impurities, high in purity, and available in glycosylation form. It can be modified with fluorination or other modifications to meet your needs.</p>

<p>2-Amino-2-N-carbobenzoxy-2-deoxy-D-mannose is a custom synthesis product that can be produced with high purity. It has a CAS number of 137157-50-7 and is an oligosaccharide, polysaccharide, and carbohydrate. 2-Amino-2-N-carbobenzoxy-2-deoxy-D-mannose is synthesized by the methylation of 2,3,4,6 tetraaminopyrimidine with formaldehyde to give 1,4 diaminocyclohexane. This compound is then reacted with carbonyl chloride to give carbamoyl chloride. The last step in the synthesis process is reacting this compound with 2,3,4,6 tetraaminopyrimidine to give the final product.</p>

<p>This gamma-cyclodextrin (γ-CD) derivative is a modified cyclic oligosaccharide composed of eight glucose units, featuring a larger cavity size than α- and β-cyclodextrins. This structural characteristic allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.</p>

<p>Trans-beta-D-glucopyranosyl methylacetoacetate is a carbohydrate that belongs to the group of modified sugars. It is a synthetic compound and can be custom synthesized for your specific needs. This product has a high purity and can be used in research or as a starting material for the synthesis of other compounds. Trans-beta-D-glucopyranosyl methylacetoacetate is an oligosaccharide that can be fluorinated, methylated, glycosylated, or click modified. This product is also available in various grades, such as standard and high purity.</p>

<p>Methyl 3-O-Benzyl-N-butyl-2,4-dideoxy-2,4-imino-a-L-ribopyranoside is a high purity compound that is custom synthesized to order. It has been fluorinated and modified with methyl groups. Methyl 3-O-Benzyl-N-butyl can be used in glycosylation and click chemistry reactions. This product is a complex carbohydrate that can be used in the synthesis of oligosaccharides and saccharides.</p>

<p>2-Azido-((R)-3,5-O-benzylidene)-2,6-dideoxy-1,4-di-O-tert.butyldimethylsilyl--L--mannopentose is a carbohydrate that is used in the synthesis of oligosaccharides and polysaccharides. It can be custom synthesized with high purity and desired modifications to suit your needs. This product has been fluorinated and glycosylated for increased stability and solubility in organic solvents. This product's CAS number is 617072-75-0.</p>

<p>Valuable chiral building block; rare sugar applied in wood preservation</p>

<p>O-(2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranosyl)-N-hydroxysuccinimide is a glycosylation agent that can be used in the synthesis of glycoproteins and polysaccharides. It has been shown to be effective for the synthesis of oligosaccharides, polysaccharides and complex carbohydrates. The compound has a CAS number of 170590-84-8 and is classified as an intermediate organic chemical. O-(2-Acetamido-3,4,6-tri-O-acetyl-2 -deoxy--b--D--glucopyranosyl)-N--hydroxysuccinimide reacts with primary alcohols to form acetal derivatives. This reaction can also be used for Click chemistry and fluorination in order to modify saccharide structures.</p>

<p>1,6-Anhydro-2-deoxy-2-iodo-b-D-glucopyranose is a sugar that has been used in the synthesis of a number of organic compounds. It is an intermolecular hydrogen bond donor, and it forms hydrogen bonds with other molecules. The molecular structure of 1,6-Anhydro-2-deoxy-2-iodo-b-D-glucopyranose consists of a six carbon chain with three hydroxyl groups and two ether groups.</p>

<p>(2S, 3S, 4R) -2- [(1R) - 1, 2-Dihydroxyethyl] -3, 4- pyrrolidinediol is a benzyl-containing compound that is used as a glycoside hydrolase inhibitor. It has been shown to be an effective treatment for inflammatory bowel disease. This drug binds to the active site of glycosidases and blocks the hydrolysis of c-glycosides in the intestine. (2S, 3S, 4R) -2- [(1R) - 1, 2-Dihydroxyethyl] -3, 4- pyrrolidinediol also inhibits chloride channels and has been shown to have antiinflammatory properties.</p>

<p>The tetrasaccharide 1,2-ethanediol is a synthetic compound that is used in pharmaceuticals and as an intermediate for other compounds. This product is a high purity custom synthesis that can be used for methylation or glycosylation reactions. The CAS number for this product is 615-86-1.</p>

Dapagliflozin is a sodium-glucose cotransporter subtype 2 (SGLT2) inhibitor that can be used in the treatment of diabetes mellitus type 2. SGLT2 is located in the proximal convoluted tubule and when it is inhibited the reabsorption of glucose into the kidneys is prevented and instead glucose is excreted in the urine. As a result glucose levels are reduced. Dapagliflozin is metabolized into to its inactive metabolite 3-O-glucuronide by the UGT1A9 enzyme present in the liver and the kidneys. In addition, dapagliflozin has been shown to cause weight loss and decrease the risk of cardiovascular events such as congestive heart failure.

<p>Fully protected xylopyranoside</p>

<p>Dextran is α-(1,6)-linked α-D-glucan with α-(1,3)-linked glucose branch points produced by fermentation of Leuconostoc mesenteroides via the action of the enzyme dextransucrase on sucrose.  The main use for native dextran is as an extender in blood transfusions and products having a range of sharp cut-off molecular weights are produced commercially for this and other applications. A complex of iron with dextran, known as iron dextran, is used as a source of iron for baby piglets which are often anaemic at birth.</p>

1,3,5-Tri-O-benzoyl-2-deoxy-2-bromo-alpha-L-arabinofuranose is a complex monosaccharide that can be used as a building block in the synthesis of various compounds. It is a derivative of the sugar arabinose, with the addition of benzoyl and bromo groups at specific positions. The compound has potential applications in the fields of organic chemistry and medicinal chemistry and is available for research.

Methyl 2-amino-2-deoxy-β-D-glucopyranoside hydrochloride is a synthetic compound that is a sugar derivative. The methyl group in this molecule can be used for the synthesis of saccharides, oligosaccharides, and other complex carbohydrates. This product has a CAS number of 3867-93-4. It is soluble in water and has a purity of at least 98%.

<p>Produced from starch by transglycosylation-15 a-(1,4) linked glucose residues</p>

<p>k-carrageenan derived octasaccharide alcohol tetrasulfate+(3-6 anhydrogalactose)</p>

<p>Allyl α-D-galactopyranoside is a colorimetric reagent that reacts with the polysaccharides to form a colored product. The reaction is based on the transfer of an allyl group from the reagent to the polysaccharide. This reaction can be performed using atomic force microscopy and microscopy techniques, as well as using light and UV-visible spectroscopy. The reaction can also be used to measure glycopolymer concentrations. A titration procedure has been developed for this purpose, in which an excess of allyl α-D-galactopyranoside is added to a solution containing galactose and ammonium sulfate. Allyl α-D-galactopyranoside reacts with galactose to produce an insoluble precipitate that can be measured by weighing or using optical density measurements at a certain wavelength.</p>

Galactosyllactose attenuated NF-κB inflammatory signaling in human intestinal epithelial cells and in human immature intestine. Thus, galactosyllactoses are strong anti-inflammatory agents in human colostrum and early milk, contributing to innate immune modulation. This product has a 13C heavy-label and so can be used in applications such as metabolic tracing and quantitative mass spectrometry.

<p>Ethyl 2,3,4,6-tetra-O-acetyl-D-thiomannopyranoside is a high purity custom synthesis sugar that can be modified with fluorination, glycosylation and methylation. This compound has CAS No. 79389-52-9. Ethyl 2,3,4,6-tetra-O-acetyl-D-thiomannopyranoside is a complex carbohydrate that is also an oligosaccharide and monosaccharide. It has many applications in the food industry as well as pharmaceuticals.</p>

<p>Sialylated tetrasaccharide found in human milk.Possible health benefits for the neonate, by supporting resistance to pathogens, gut maturation, immune function, and cognitive development.</p>

<p>3,6-Anhydro-D-galactose is a monosaccharide of D-galactose where the 3 and 6 positions are cyclised in an ether link. 3,6-Anhydro-D-galactose is found naturally occurring in Rhodophyta (Red Algae) and is a constituent of the sulphated polysaccharide PLS, which has shown anti-inflammation activity and anti-nociceptive effects. In addition, sulphated polysaccharide is capable of inhibiting the in vitro replication of Herpes simplex virus type 1 (HSV-1) and HIV-1.<br>Our 10% aqueous solution is a 10% wt/wt solution of 3,6-Anhydro-D-galactose in water. 10 mg MA07897 contains 1 mg 3,6-Anhydro-D-galactose.<br>We also offer the same product in a non-aqueous solution, MA05223.</p>

<p>(3S, 5S) -1-Isopropyl-3, 4, 5- piperidinetriol is a synthetic oligosaccharide that has been modified by fluorination and glycosylation. It is synthesized from a sugar that is then methylated. This compound has a CAS number of 85314-88-5. It is used as an ingredient in food products to provide sweetness and bulk to baked goods.</p>

Important resource for RNA- and DNA-related syntheses including ribosylation

<p>2,3,4,6-Tetra-O-acetyl-D-galactopyranosyl azide is a fluorinated sugar that can be used as a synthetic intermediate for the glycosylation of polysaccharides. This compound has been shown to have high purity and does not react with other compounds in the reaction mixture.</p>

<p>For more than two decades, there has been substantial interest in developing novel membrane mimics specifically targeted for the biochemical and biophysical characterization of membrane proteins. Examples include new types of detergents, such as cycloalkyl maltosides (CYMAL detergents).</p>

<p>Glycyl-monosialyllacto-N-neohexose I is a monosaccharide that is used as a building block in the synthesis of complex carbohydrates. It is custom synthesized and purified to high purity. This product can be fluorinated and methylated, which allows for the attachment of glycosyl groups. Glycyl-monosialyllacto-N-neohexose I is also a sugar with a CAS number. It has an average molecular weight of 137.14 g/mol and is made up of three atoms: carbon, hydrogen, and oxygen.</p>

<p>Cochineal is a natural dye that is extracted from the female cochineal insect. Cochineal is used in food and cosmetics, and as a red colorant in some pharmaceutical products. The carminic acid present in cochineal forms a stable complex with the anionic groups present in wool or silk, so it is not soluble in water. Cochineal has been shown to have genotoxic activity and can cause mutations at both the base-pairing level and at protein level. Cochineal has also been shown to be cytotoxic against human serum cells and disrupt mitochondrial membrane potential. Its optimum concentration for signal peptide detection by electrochemical impedance spectroscopy (EIS) was found to be 0.1 mM.</p>

<p>Food additive, applied in pharmaceuticals and beauty products.</p>

<p>Precursor of N-acetylneuraminic acid</p>

<p>Octyl b-D-glucuronic acid is a custom synthesis of an oligosaccharide with a high purity. It is a modification of a carbohydrate, which is a complex carbohydrate. This product has been synthesized by methylation and glycosylation. Octyl b-D-glucuronic acid has many applications in the chemical industry due to its fluoroquinolone resistance and its high purity. This product is used as an excipient in pharmaceuticals, foods, and cosmetics.</p>

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

<p>2-Acetamido-6-O-(2-acetamido-2-deoxy-a-D-galactopyranosyl)-2-deoxy-D-galactopyranose is an n-acetylated disaccharide (naturally occurring) that is a glycosidic bond between the two sugars, n-acetyl D galactosamine and 2,3,4,6 tetraacetamido 2 deoxy D galactose. This compound has an acetamide residue in place of a hydroxyl group on the second carbon atom of the sugar. The linkage between these two sugars is a glycosidic bond. In its natural form, this molecule can be found in mammalian cells and bacterial cell walls.</p>

1-Deoxy-2,3:4,5:6,7-Tris-O-(1-methylethylidene)-D-glycero-D-guloheptitol is a high purity custom synthesis sugar that can be modified with fluorination and glycosylation. This product is synthesized from monosaccharides and saccharides. It has the CAS No. 1801528-80-2 and molecular weight of 354.25 g/mol. 1,2,3,4,5,6,7 -Tris (1 methylethylidene) -D glycero D gulo heptitol is a complex carbohydrate that is used in the synthesis of oligosaccharides and monosaccharides.

<p>2,3,4,6-Tetra-O-benzoyl-1-deoxy-D-arabino-hex-1-enopyranose is a glycosyl compound that has been synthesized by the elimination of trifluoride and alcohols. It is used as a starting material for the synthesis of other compounds. This compound can react with halides to form etherate or ester derivatives. 2,3,4,6-Tetra-O-benzoyl-1-deoxy-D-arabino hexane can also be reacted with boron trifluoride or boron trifluoride etherate to form eliminations.</p>

<p>GDP-L-fucose is a natural fucosyl donor and substrate for fucosyltransferases (FUT) that catalyses the fucosylation of, for example, human milk oligosaccharides or glycoproteins. GDP-L-fucose is widely used in (chemo)enzymatic synthesis of glycans. Cymit Quimicaesis of GDP-L-fucose, a nucleotide sugar consisting of an L-fucose that is β-glycosidically linked to the nucleotide guanosine diphosphate (GDP), is achieved either through de novo synthesis via GDP-mannose or through a salvage pathway from free fucose. Fucosylation is catalysed by fucosyltransferases (~ 13 FUT genes have been identified in the human genome to date) to generate α-1,2, α-1,3, α-1-4 and α-1-6 linkages of fucose to other sugars, as well as direct linkages to peptides, with release of GDP (Lairson, 2008).</p>