Glicoscienza

<p>Methyl 4,6-O-benzylidene-3-deoxy-a-D-glucopyranoside is a synthetically modified high purity carbohydrate. It is an oligosaccharide that can be custom synthesized to meet your requirements. This product can be used as a complex carbohydrate in the food industry.</p>

<p>N-Acetyl-beta-D-mannosamine is a methylated sugar. It is a white crystalline solid with a molecular weight of 284.2.</p>

2,3,4,6-Tetra-O-benzyl-1-deoxynojirimycin hydrochloric acid salt is a synthetic monosaccharide. It was originally synthesized by the methylation of a native oligosaccharide before being subjected to click chemistry. The resulting product is a complex carbohydrate with an aromatic ring in place of the sugar alcohol moiety. 2,3,4,6-Tetra-O-benzyl-1-deoxynojirimycin hydrochloric acid salt has CAS number 72983-76-7 and is soluble in water. This product is also available as a custom synthesis service and can be modified to meet your needs.

<p>5,6-O-Isopropylidene-phlorigidoside B is a glycosylation inhibitor that belongs to the class of oligosaccharides and synthetic compounds. This compound has been shown to inhibit the synthesis of complex carbohydrates by reacting with a phosphoryl group on an activated sugar. The 5,6-O-isopropylidene group on the molecule is fluorinated and methylated, which may be used for custom synthesis or modification. 5,6-O-Isopropylidene-phlorigidoside B can also be used as a fluorescent probe in fluorescence microscopy.</p>

<p>2,3-O-Isopropylidene-D-allono-1.4-lactone is a methylated saccharide that has been modified by the click reaction with a phosphonate group and an isopropylidene group. The synthesis of this product can be customized to suit your needs. This product is offered in high purity, and it is an excellent source of carbohydrates or sugars. 2,3-O-Isopropylidene-D-allono-1.4-lactone also has a fluorinated group on its molecule. It is a complex carbohydrate that can be used for glycosylation or as a click modification substrate.</p>

(D-Galactopyranosyl)-b-D-thiogalactopyranoside is a synthetic disaccharide, specifically used in biochemical and molecular biology research. It is often derived through chemical synthesis using various monosaccharide precursors, designed to mimic natural disaccharides with a modified linkage. This compound acts as a non-metabolizable analog of lactose and can inhibit enzymes like β-galactosidase due to its structural similarity. Importantly, its sulfur-containing thiol linkage imparts unique stability and reactivity characteristics distinct from natural glycosidic bonds.The primary application of (D-Galactopyranosyl)-b-D-thiogalactopyranoside is in research studies exploring carbohydrate-protein interactions, enzyme inhibition assays, and the specificity of galactoside-binding proteins. It serves as a tool to elucidate the mechanics of glycosidases and to develop enzyme assays critical for the study of metabolic pathways involving galactosides. Further, it finds use in diagnostics as a reporter substrate in assays where differentiation from native substrates is necessary. Its role in these applications highlights the compound's utility in advancing scientific knowledge of carbohydrate biochemistry.

Sialylated trisaccharide found in human urine

<p>Methyl 2,3,4-tri-O-pivaloyl-6-O-triisopropylsilyl-a-D-glucopyranoside is a synthetic, fluorinated monosaccharide that belongs to the group of oligosaccharides. It is used in the synthesis of complex carbohydrates. Methyl 2,3,4-tri-O-pivaloyl-6-O-triisopropylsilyl-a-D-glucopyranoside is a custom synthesis and can be modified with methylation or click chemistry. Methyl 2,3,4 - tri - O - pivaloyl - 6 - O - triisopropylsilyl - a - D - glucopyranoside has CAS number <br>Methyl 2,3,4 – tri – O – pivaloyl – 6 – O – triisopropylsily</p>

<p>5,6-Dichloro-5,6-dideoxy-b-L-talofuranose is a carbohydrate. It is a saccharide with a molecular formula of C7H8Cl2O4 and a molecular weight of 245.1. This compound has been modified by fluorination and methylation. 5,6-Dichloro-5,6-dideoxy-b-L-talofuranose is stable in the presence of acid or base at room temperature and has a melting point of &gt;200°C. The CAS number for this compound is 677638-78-0. 5,6-Dichloro-5,6-dideoxy-b -L -talofuranose is available for custom synthesis to order with high purity and can be glycosylated or click modified to order.</p>

<p>Click reagent for metabolic labeling of GlcNAc</p>

<p>Inhibitor of alpha-glucosidase</p>

<p>1,4-Dideoxy-1,4-imino-D-arabinitol (1,4DA) is an inhibitor of glycolysis that has potent inhibitory activity against the enzyme phosphofructokinase. It has been shown to decrease cellular ATP levels in rat liver and kidney tissues. 1,4DA also inhibits urine production by inhibiting the conversion of fructose to glucose in the kidney. This compound is a racemic mixture with two enantiomers: R and S. The pharmacokinetics of 1,4DA have been studied in rats and humans using a model system. In rats, 1,4DA was absorbed rapidly and excreted unchanged in the urine. In humans, this drug was well absorbed after oral administration and metabolized mainly by hydrolysis to form 1,4-dideoxyfructose (Fru).</p>

<p>Glycosylation, complex carbohydrate, Methylation, Click modification, Polysaccharide, Fluorination, saccharide and Modification of sugars are some of the reactions that can be performed on this compound. It is a synthetic monosaccharide with CAS No. 78013-18-0. This product is available for custom synthesis and has been shown to have high purity.</p>

<p>PolyGlycopleX (PGX) is produced from a mixture containing proprietary proportions of three polysaccharides, konjac glucomannan, xanthan gum and sodium alginate.  Recent hydrodynamic, rheological and analytical studies have shown that the unexpectedly high viscosity of solutions of PGX is consistent with an interaction between a konjac glucomannan, xanthan gum complex and sodium alginate to form a new, ternary complex in solution. Human and animal feeding studies have shown that PGX can be used to control weight, lower the glycaemic index of foods and postprandial glycaemia.</p>

<p>1-Azetidinecarboxylic acid, 3-[(2R,3S,4S)-4-hydroxymethyl-3- hydroxy-1-azetidinyl]-, (1R) -1- [(2R, 3S,4S) -4-hydroxymethyl-3- hydroxy-1-azetidinyl] -1, 2-ethanediol is a complex carbohydrate that belongs to the group of polysaccharides. It has been modified by methylation and glycosylation. This product has high purity and is fluorinated for solubility.</p>

Methyl 2-amino-2-deoxy-β-D-glucopyranoside hydrochloride is a synthetic compound that is a sugar derivative. The methyl group in this molecule can be used for the synthesis of saccharides, oligosaccharides, and other complex carbohydrates. This product has a CAS number of 3867-93-4. It is soluble in water and has a purity of at least 98%.

<p>Produced from starch; white hygroscopic spray-dried powder; easily digestible</p>

High mannose oligosaccharide found in urine of mannosidosis patients

<p>Galactosyllactose attenuated NF-κB inflammatory signaling in human intestinal epithelial cells and in human immature intestine. Thus, galactosyllactoses are strong anti-inflammatory agents in human colostrum and early milk, contributing to innate immune modulation. This product has a 13C heavy-label and so can be used in applications such as metabolic tracing and quantitative mass spectrometry.</p>

<p>Glycyl-Oligosaccharidesmannose 6 are custom synthesized and modified to contain fluorine atoms. These compounds are used as a reagent in organic synthesis, chemical modification, and biochemistry. They have been used for the methylation of saccharide and carbohydrate molecules, including glycosylation reactions. Glycyl-Oligosaccharidesmannose 6 can be used for the preparation of polysaccharides, which are complex carbohydrates.</p>

<p>Custom synthesis, Modification, Fluorination, Methylation, Monosaccharide, Synthetic, Click modification, Oligosaccharide, saccharide, CAS No., Polysaccharide. Glycosylation. Sugar. Carbohydrate. Complex carbohydrate.</p>

<p>1,2,3,4,6-Penta-O-acetyl-5-thio-D-galactopyranose is an oligosaccharide that is synthesized by the fluorination of a 5-thiogalactopyranosyl fluoride and subsequent glycosylation. It can also be made by methylation of a 3,4,6 pentaacetylgalactosamine with formaldehyde and sodium cyanoborohydride. It is a complex carbohydrate that has been shown to have antiviral activity against HIV.</p>

<p>5-O-tert-Butyldimethylsilyl-2,3-O-isopropylidene-L-ribono-1,4-lactone is a high purity custom synthesis and custom synthesis of complex carbohydrates. 5-O-tert-Butyldimethylsilyl-2,3-O-isopropylidene-L-ribono--1,4--lactone is a fluorination and an oligosaccharide that contains methylated sugar. It is a polysaccharide with a click modification that can be used for glycosylation and methylation. This product has been shown to be effective in the synthesis of oligosaccharides.</p>

<p>Food additive, applied in pharmaceuticals and beauty products.</p>

<p>Octyl b-D-glucuronic acid is a custom synthesis of an oligosaccharide with a high purity. It is a modification of a carbohydrate, which is a complex carbohydrate. This product has been synthesized by methylation and glycosylation. Octyl b-D-glucuronic acid has many applications in the chemical industry due to its fluoroquinolone resistance and its high purity. This product is used as an excipient in pharmaceuticals, foods, and cosmetics.</p>

<p>2-Acetamido-6-O-(2-acetamido-2-deoxy-a-D-galactopyranosyl)-2-deoxy-D-galactopyranose is an n-acetylated disaccharide (naturally occurring) that is a glycosidic bond between the two sugars, n-acetyl D galactosamine and 2,3,4,6 tetraacetamido 2 deoxy D galactose. This compound has an acetamide residue in place of a hydroxyl group on the second carbon atom of the sugar. The linkage between these two sugars is a glycosidic bond. In its natural form, this molecule can be found in mammalian cells and bacterial cell walls.</p>

1-Deoxy-2,3:4,5:6,7-Tris-O-(1-methylethylidene)-D-glycero-D-guloheptitol is a high purity custom synthesis sugar that can be modified with fluorination and glycosylation. This product is synthesized from monosaccharides and saccharides. It has the CAS No. 1801528-80-2 and molecular weight of 354.25 g/mol. 1,2,3,4,5,6,7 -Tris (1 methylethylidene) -D glycero D gulo heptitol is a complex carbohydrate that is used in the synthesis of oligosaccharides and monosaccharides.

Allyl 2-O-benzoyl-3-O-benzyl-a-L-rhamnopyranoside is a complex carbohydrate that can be used in the synthesis of saccharides and polysaccharides. It has been modified by methylation, glycosylation, and carbamylation. The CAS number for this product is 940274-21-5.

<p>Agarose is a polysaccharide found in red algae, typically Gelidium and Gracilaria. It is a strictly alternating polysaccharide of α-1,3 linked D-galactose and β-1,4 linked L-3,6 anhydrogalactose with occasional sulfation at position 6 of the anhydrogalactose residue. Agaro-oligosaccharides result from cleavage at galactose residues and neoagaro-oligosaccharides from cleavage at 3,6-anhydro residues. Neoagarodecaose is reported to have potential for novel cosmeceuticals.</p>

<p>GDP-L-fucose is a natural fucosyl donor and substrate for fucosyltransferases (FUT) that catalyses the fucosylation of, for example, human milk oligosaccharides or glycoproteins. GDP-L-fucose is widely used in (chemo)enzymatic synthesis of glycans. Cymit Quimicaesis of GDP-L-fucose, a nucleotide sugar consisting of an L-fucose that is β-glycosidically linked to the nucleotide guanosine diphosphate (GDP), is achieved either through de novo synthesis via GDP-mannose or through a salvage pathway from free fucose. Fucosylation is catalysed by fucosyltransferases (~ 13 FUT genes have been identified in the human genome to date) to generate α-1,2, α-1,3, α-1-4 and α-1-6 linkages of fucose to other sugars, as well as direct linkages to peptides, with release of GDP (Lairson, 2008).</p>

(3R, 5R) -1-Benzyl-3, 4, 5- piperidinetriol hydrochloride is a synthetic compound that is used for the production of oligosaccharides and saccharides. This molecule is a part of the glycosylation reaction and has been modified to produce a variety of carbohydrate products. The CAS number for this compound is 6078-73-5 and it can be synthesized in various lengths. The chemical name for this compound is (3R, 5R)-1-(benzyloxycarbonyl)-3,4,5-piperidinetriol hydrochloride.

<p>Anthrose is a high purity, custom synthesis, and oligosaccharide. It can be modified with fluorination, glycosylation, and methylation. Anthrose is used for the synthesis of complex carbohydrate.</p>

Alkylsophorolipids are custom-synthesized complex carbohydrates. They are composed of an oligosaccharide and methylated saccharides, which have been modified with fluorine at the C3 position. This modification increases the hydrophobicity of the molecule, which makes it more soluble in organic solvents such as chloroform. Alkylsophorolipids have a CAS number of 1269-61-6.

<p>N,O-Didesmethyl venlafaxine D-glucuronide is a custom synthesis, complex carbohydrate. It is an Oligosaccharide with CAS No. that is Polysaccharide and Modification. It has Methylation and Glycosylation. The saccharide in the molecule is a sugar or Carbohydrate and sugar. The high purity of the product makes it Fluorination and Synthetic.</p>

<p>Methyl 2-deoxy-D-ribofuranoside is a methylglucoside that is synthesized by the reaction of thiourea with chloroacetic acid. The anomers of this compound are atypical and the product can be obtained in high yield (70%) by the use of chromatographic purification. This chemical has been used to produce a variety of compounds including carbamates, chloroacetamides, sulfonamides and others. Methyl 2-deoxy-D-ribofuranoside is also an intermediate for asymmetric synthesis. It can act as a catalyst for reactions involving alkali metals and nucleophiles such as chloride, hydantoin and dimethylformamide. The structure of this molecule has been determined by nmr spectroscopy and its 1H NMR spectrum is consistent with that predicted from its molecular formula.</p>

<p>3-O-benzyl-D-xylose is a sugar that belongs to the group of dimethyl, diisobutylaluminium, dicarboxylate, malonate, oxygenated, acetylation, cyclopentane. It has been shown to be effective in cleavage and condensation reactions. 3-O-benzyl-D-xylose can be used in the synthesis of pyridinium chlorochromate and chlorochromate. This compound also reacts with pyridinium via hydride reduction and hydroxide cleavage.</p>

<p>N- [(3R, 4R, 5R) - 4- (Acetyloxy) - 5- [(acetyloxy) methyl] -1- benzyl- 3- pyrrolidinyl] -acetamide is a custom synthesis of our company. It can be used to synthesize oligosaccharides and polysaccharides by click modification. It is also used for fluorination of complex carbohydrates, saccharide and sugar.</p>

<p>6'-a-Sialyl-N-acetyllactosamine-sp-biotin is a recombinant modified oligosaccharide. It is an Oligosaccharide that is synthesized by the methylation of 6'-sialyllactose with acetic anhydride and triethylamine in DMF. It has a molecular weight of 805.00 Da and a CAS number of 1038746-08-5. 6'-a-Sialyl-N-acetyllactosamine-sp-biotin may be used as a monomer for click chemistry, as well as for other applications in carbohydrate chemistry, such as the synthesis of polysaccharides and complex carbohydrates. This product has high purity and can be custom synthesized to order.</p>

Kojitriose is a disaccharide composed of two glucose molecules. It has been shown to have insulin-sensitizing effects in animals and humans. Kojitriose binds to the surface of Streptococcus faecalis and prevents the growth of this bacteria. Kojitriose also has an inhibitory effect on mesenteroides, which are a type of bacterium found in the human gut. This disaccharide is enzymatically hydrolyzed to produce hydrogen fluoride, which inhibits the growth of Streptococcus faecalis and mesenteroides. The enzyme trehalase is responsible for this hydrolysis reaction, while hydroxyl groups act as nucleophiles that react with chloride ions to form hydrogen fluoride.

<p>GD3 ganglioside (shown as sodium salt) has a core disaccharide structure (Gal-1,4-Glc) with two sialic acids linked to the non-reducing galactose residue, and ceramide linked to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GD3 ganglioside is a minor ganglioside in most normal tissues but plays a crucial role in the development of the brain; its presence is significantly reduced in adults. However, expression of GD3 ganglioside is increased in pathological conditions, such as, cancers and neurodegenerative disorders (Malisan, 2002). GD3 ganglioside was the first cancer-associated ganglioside discovered, that promotes adhesion and invasion of cancers. GD3 ganglioside and GD2 ganglioside are highly expressed in a various malignant cancers and have become potential targets for next-generation cancer therapy (Liu, 2018).</p>

<p>6-Deoxy-L-allitol is a white crystalline solid that melts at 122°C. It has an amorphous character and may be present as a mixture of rotations, form, and crystalline polymorphs. 6-Deoxy-L-allitol can be oxidized to its diol derivative by hydrogen peroxide or sodium periodate. This compound is soluble in water, methanol, and acetone. The molecular weight of this compound is 179.06 g/mol.</p>

3-C-Methyl-allonolactone is an oligosaccharide that is modified by methylation, glycosylation, and polysaccharide. It is a custom synthesis and has a high purity. 3-C-Methyl-allonolactone may be used as a precursor to 3-carbon sugars.

<p>D-Galactopyranosyl-(b1-3)-[N-acetylneuraminyl-(a2-6)]-D-N-acetylgalactosaminyl serine-biotin is a Glycosylation, complex carbohydrate. It is a Methylation, Click modification, Polysaccharide. This product is Fluorinated.</p>

<p>2-Amino-2-deoxy-6,7-O-isopropylidene-D-glycero-D-ido-heptono-1.4-lactone is a carbohydrate that belongs to the group of saccharides and oligosaccharides. It is an analogue of heptose and is synthesized in two steps from 2,3,4,5,6,7,8,9-octahydroxycyclohexanone by fluorination followed by methylation. This compound has been used as a nonenzymatic glycosylase substrate in the click chemistry. The synthesis of this compound can be customized according to customer specifications such as purity and monosaccharide content.</p>

<p>This compound is a custom synthesis, modification and fluorination of an acetylated glycoside. It is a methylated monosaccharide with a saccharide at the reducing end. This product can be used in the synthesis of oligosaccharides, glycosylation and sugar modifications. The CAS number for this compound is 58907-27-3.</p>

<p>Ethyl 3-amino-b-D-glucuronide is a product that can be custom synthesized. It is a white to off-white powder with a molecular weight of 168.14 g/mol and a melting point of below 200°C. Ethyl 3-amino-b-D-glucuronide is soluble in water, ethanol and ether, but insoluble in hexane and petroleum ether. The CAS number for this product is 97705-82-2. This product has the following features: Glycosylation, complex carbohydrate, Methylation, Click modification, Polysaccharide, Fluorination, saccharide, Modification, sugar, Oligosaccharide.</p>

<p>Genistin is an isoflavone found in soybeans and other plants. It has antioxidative properties, which may be due to its ability to scavenge free radicals. Genistin also has protein-binding activity, and it can inhibit the growth of certain insects by binding to their DNA. Genistin can also bind to a number of enzymes and affect their activities, including amylase, chymotrypsin, trypsin, and lipase. It is also involved in energy metabolism and protein synthesis. The physiological effects of genistin are not well understood but may be related to its ability to act as a phytoestrogen or mimic estrogen.</p>

Ethyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranoside is a compound with a molecular mass of 536.35 Da. It is an inhibitor of the enzyme catalase and has been shown to bind to monoclonal antibodies that are specific for human vascular endothelial growth factor (VEGF). This inhibition prevents the binding of VEGF to its receptor, which blocks the activation of the VEGF pathway. Ethyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy--b D glucopyranoside has also been shown to inhibit HIV replication in vitro.

<p>Dextran sulphate is a dextran derivative whose ulcer (colitis) -causing properties were first reported in hamsters and extrapolated a few years later to mice and rats. The exact mechanisms through which dextran sulphate induces intestinal inflammation are unclear but may be the result of direct damage of the monolayer of epithelial cells in the colon, leading to the crossing of intestinal contents (for e.g. commensal bacteria and their products) into underlying tissue and therefore induction of inflammation.  The dextran sulphate sodium induced ulceration model in laboratory animals has some advantages when compared to other animal models of colitisdue to its simplicity and similarities to human inflammatory bowel disease.</p>

4-O-Methyl-β-L-arabinopyranose is an L-arabinose glycoside