Glicoscienza

D-Melibiose anhydrous is a disaccharide that is used as an excipient in the pharmaceutical industry. It has been shown to be an active enzyme, which may be due to its ability to sequester galactose. D-Melibiose anhydrous has a redox potential of -0.2 V, indicating that it has a high number of oxidizable groups. The molecular weight of this sugar is 324.14 g/mol, and it has a polarizability of 0.16 D, which classifies it as a polyol with hydrogen bonding properties. This sugar is not soluble in water but can be dissolved in ethanol or propylene glycol. D-Melibiose anhydrous also has carbohydrate properties and may be considered a sugar alcohol because it contains six carbon atoms and one oxygen atom.

β-1,3-Glucan is a bioactive polysaccharide, which is located predominantly in the cell walls of yeast, fungi, and certain cereals. This compound is characterized by its unique branched structure, which is crucial for its biological function. The mode of action of β-1,3-Glucan involves the binding to specific receptors on immune cells, such as dectin-1, which triggers a cascade of immune responses. This interaction enhances the activity of macrophages, neutrophils, and natural killer cells, thus bolstering the body's innate immune defenses.The uses and applications of β-1,3-Glucan are broad, primarily focused on immunological research and potential therapeutic strategies. It is extensively utilized in studies examining its effects as an immunomodulator, leveraging its ability to potentiate immune system function and examining its role in adjunctive cancer therapies, where it may enhance the efficacy of certain treatments. Additionally, β-1,3-Glucan is investigated for its potential benefits in reducing infection rates and improving recovery times in clinical settings. Moreover, its applications in dietary supplements and functional foods continue to be a subject of scientific inquiry, aiming to harness its health-promoting properties within nutrition science.

<p>Sialyllactose-BSA is a complex carbohydrate that is used in the synthesis of saccharides. It has been modified with fluorination to create a 6'-sialyllactose-BSA, which is a monosaccharide. This product can be custom synthesized and it's purity is high. The product can be methylated or glycosylated, and it has been click-modified for fluorescence labeling.</p>

Onitin 2'-O-glucoside is a sugar that is custom synthesized and purified. It is a modification of oligosaccharides, complex carbohydrates, and polysaccharides. Onitin 2'-O-glucoside is an Oligosaccharide Carbohydrate which can be used in the synthesis of high purity monosaccharides and methylations. It also has the ability to form glycosylation with saccharides, such as glucose or fructose. This product can also be fluorinated to produce saccharides that are water soluble.

Intermediate in the synthesis of empagliflozin

<p>6-Phosphogluconic acid trisodium is a synthetic, non-natural glycosylation product that is used as a building block in the synthesis of complex carbohydrates. It can be fluorinated or methylated, and modified with a click reaction to produce various derivatives. The compound has been shown to have high purity and is readily available from commercial suppliers.</p>

<p>GT3 oligosaccharide (free acid) is a disaccharide (Galβ1,4Glc) with three sialic acid residues (NeuAc) linked α2,8/α2,8/α2,3 to the galactose residue (Ledeen, 2009). The GT3 ganglioside is the carbohydrate moiety in the GT3 ganglioside, which is implicated in type 1 diabetes. GT3 ganglioside is expressed on pancreatic cells and is the target antigen of anti-GM3-antibodies, which contribute to the autoimmune destruction of pancreatic beta cells (Misasi, 1997). GT3 ganglioside is also abundant in lung tissues and the nervous system.</p>

2-Acetamido-2-deoxy-D-glucopyranosyl serine is a compound that belongs to the class of coumarins and monosaccharides. It contains a nitro group and a heterocycle, making it a unique and versatile molecule. This compound has been studied for its various properties, including its interaction with liver microsomes and its ability to undergo crystallization. Additionally, 2-Acetamido-2-deoxy-D-glucopyranosyl serine has shown promising effects on TGF-beta activation and has been found to inhibit aldehyde formation in trichloroacetic acid solutions. This compound also exhibits interactions with other molecules such as pyrazine, ofloxacin, and famotidine. Its diverse characteristics make it an intriguing compound for further research and potential applications in various fields.

<p>Forodesine is a purine nucleoside that inhibits the nucleoside phosphorylase enzyme and prevents the synthesis of purines. It has minimal toxicity and is effective against intracellular targets such as mitochondria, which are important for apoptosis induction. Forodesine also inhibits the mcl-1 protein, which is an inhibitor of t-cell lymphomas. This drug has been shown to be effective in animal models of human lymphoma and leukemia.</p>

<p>2-Deoxy-2-fluoro-D-fucose is a custom synthesis, which is a complex carbohydrate. It has CAS No. and polysaccharide modification and can be methylated, glycosylated, or fluorinated. The molecular weight of this product is high purity and it can be used as a sugar or carbohydrate. Click modification is possible with 2-deoxy-2 fluoro-D-fucose.</p>

2,3,4,6-Tetra-O-acetyl-D-mannopyranose is a stereoselective technique used for the production of trisaccharides. It is also an acetylated form of D-mannopyranose that is obtained by acetylation of D-mannopyranose with acetic anhydride in the presence of hydrochloric acid or pyridine. The compound can be obtained as either levorotatory or dextrorotatory isomers depending on whether the hydroxyl group or carbonyl group are in the axial position. 2,3,4,6-Tetra-O-acetyl-D-mannopyranose can be used as a substrate for enzyme preparations to produce aminoglycoside antibiotics such as hygromycin A. Acetylation increases the solubility and stability of this drug and reduces its toxicity to humans

Please enquire for more information about D-Maltose monohydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page

L-Lyxosamine HCl is a synthetic monosaccharide that has been modified to contain a fluorine atom. L-Lyxosamine HCl is a methyl donor in the Methylation reaction and can be used as an intermediate for the synthesis of oligosaccharides and polysaccharides. This product is available in high purity, with an average yield of 97%. The CAS No. for this product is 590-81-6.

<p>Please enquire for more information about Mono-(6-(diethylenetriamine)-6-deoxy)-β-Cyclodextrin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Methyl 2-deoxy-5-O-toluoyl-L-ribofuranoside is a high purity, custom synthesis, methylated, Glycosylation and Oligosaccharide. It has CAS No. 676598-19-9 and is Glycosylated and Methylated. This complex carbohydrate is a synthetic, monosaccharide or saccharide that can be modified with fluorination, Click modification or glycosylation.</p>

<p>4-Methoxyphenyl b-D-galactopyranoside is a custom synthesis of a sugar with an active methyl group. It is synthesized by the Click modification of 4-hydroxyphenyl b-D-galactopyranoside and has been fluorinated. The glycosylation process has been carried out using glycone as a precursor to modify the monosaccharide and oligosaccharide. This product has a CAS number of 3150-20-7 and is considered a synthetic compound.</p>

<p>Please enquire for more information about N-(Formylamidino)-N-b-D-ribofuranosylurea including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>D-Gluconic acid potassium salt is a glycol ether with biochemical properties that can be used to synthesize covalent linkages. It has been shown to have antimicrobial properties in wild-type strains of Escherichia coli and Salmonella typhimurium. D-Gluconic acid potassium salt has been shown to exhibit inhibitory effects on the synthesis of DNA, RNA, and protein, as well as enzyme activities. The matrix effect is an analytical method that measures the inhibition of bacterial growth in agar plates. Electrochemical impedance spectroscopy (EIS) is a technique that measures changes in electrical resistance when bacteria are placed on an electrode surface. This technique has been used to show that D-gluconic acid potassium salt exhibits inhibitory effects against group P2 enzymes, such as polymerase chain reaction (PCR), which is used for DNA replication and amplification.</p>

A fucan sulphate found in brown marine algae (Phaeophyta-typically Fucus vesiculotus, Ascophyllum nodosum, Alaria and Lessonia nigrescens (illustrated) and has been shown to have anticoagulant activity. The main constituents are α-1,4 and α-1,2 linked L-fucose sulphates although galactose also occurs and there are many variations of the basic structure found in different species of Phaeophyta. The image was kindly provided by Prof Mike Guiry from Cork who runs ‘The Seaweed Site’.

<p>Coumaric acid 4-O-glucoside is a compound that is found in plants and can be extracted from flaxseed. It has been shown to have antioxidative activity, especially in the prevention of oxidation of fatty acids. Coumaric acid 4-O-glucoside has also been shown to inhibit the synthesis of n-3 fatty acids and secoisolariciresinol, as well as to regulate the biosynthesis of these lipids. The efficient method for preparing this compound is by hydrolysis of coumaroyl ester linkages using hydrochloric acid in methanol. Coumaric acid 4-O-glucoside was synthesized by reacting methyl acetoacetate with sodium hydroxide and hydrochloric acid in methanol at a temperature range of 0°C to 25°C. This reaction was followed by purification using phase liquid chromatography.</p>