Librerie di composti

G-protein-coupled receptors (GPCRs) are the largest and most diverse group of membrane receptors in eukaryotes …

Cytokines are a broad and loose category of small proteins (~5-20 kDa) that are important …

Cardiotoxicity is one of the leading causes of drug attrition during development, and accounts for …

An autoimmune disorder occurs when the body's immune system attacks and destroys healthy body tissue …

During the past decades, we have witnessed many landmark discoveries and successes in cancer research …

A significant barrier to effective cancer therapy is the development of resistance to the drugs …

Metabolism is the set of life-sustaining chemical reactions involved in maintaining the living state of …

Hematologic diseases (hematonosis), disorders of the blood and blood-forming organs, afflict millions of Americans. In …

Given the central functional role that the ion channel superfamily plays in human physiology, its …

The 3-D structure of a potential drug target in a newly mapped protein of COVID-19, …

Adverse drug events such as cardiotoxicity, hepatotoxicity and other organ toxicities, keep surfacing in the …

Since Emil Fischer (Nobel Prize winner in Chemistry) published an article which reports the preparation …

Nature, the master of craftsman of molecules created almost an inexhaustible array of molecular entities. …

Lipids are fatty acids and their derivatives, and substances related biosynthetically or functionally to these …

During the past decades, we have witnessed many landmark discoveries and successes in cancer research …

During the past decades, we have witnessed many landmark discoveries and successes in cancer research …

Fluorine atoms have a unique combination of electronic and physical properties. As such, when incorporated …

It is well known that neurological diseases that affect the brain or other components of …

Angiogenesis is a normal and vital process in growth and development, as well as in …

A neurotransmitter receptor (also known as a neuroreceptor) is a membrane receptor protein that is …

Covalent inhibitors are small organic molecules which interact with specific target proteins and form a …

With advances in early detection and cancer treatment over the past decade, such as immunotherapy, …

During the past decades, we have witnessed many landmark discoveries and successes in cancer research …

According to Global cancer statistics 2018, the global cancer burden is estimated to have risen …

TargetMol offers a high quality Target-focused Phenotypic Screening Library (2623 compounds in total) with maximal …

Fragment-based drug discovery (FBDD) has emerged in the past decade as a powerful tool for …

The blood-brain barrier (BBB) is a highly selective semipermeable border that separates the circulating blood …

Bioactive lipids have been shown to provide health benefits either through modification of tissue fatty …

Hypertension (hypertension) is a clinical syndrome characterized by increased arterial blood pressure (systolic and/or diastolic) …

Stem cells can differentiate into other types of cells and can divide to produce more …

Nuclear factor-κB (NF-κB), a collective term for a family of transcription factors, includes five subunits: …

The 3CLpro (Mpro), also known as Nsp5, is first automatically cleaved from poly-proteins to produce …

The cytoskeleton is a complex, dynamic network of interlinking protein filaments present in the cytoplasm …

All compounds in FDA approved drug library have well-characterized biological activity, clear targets, safety, and …

Communication between and within neurons is critical for all functions of the nervous system, from …

Ferroptosis is a type of programmed cell death dependent on iron and characterized by the …

Mitogen-activated protein kinases (MAPKs) are a highly conserved family of serine/threonine protein kinases involved in …

Microscopic organisms, commonly known as microorganisms or microbes, are found all around us and even …

Clinical compound library is a collection of 3142 compounds, all of which have been permitted …

The phosphatase inhibitor compound library is a collection of 80 phosphatase inhibitors with known activity, …

A protein kinase is a kinase enzyme that modifies other molecules, mostly proteins, by chemically …

During the treatment of Covid-19 in China, the intervention of traditional Chinese medicine (TCM) reduced …

During the past decades, we have witnessed many landmark discoveries and successes in cancer research …

Members of the transforming growth factor-β (TGF-β) family control growth, differentiation and apoptosis of cells, …

Preclinical Compound Library is a collection of 709 compounds that are in preclinical phase with …

Chromatin modification, also called Chromatin remodeling, is the rearrangement of chromatin from a condensed state …

Apoptosis is a form of programmed cell death that occurs in multicellular organisms. In contrast …

Cardiovascular disease generally refers to all types of diseases that affect the heart or blood …

Nucleoside analogues are nucleosides which contain a nucleic acid analogue and a sugar. Nucleotide analogs …

The PI3K/AKT/mTOR pathway is an intracellular signaling pathway important in regulating the cell cycle. Therefore, …

In response to the outbreak of COVID-19 caused by a novel coronavirus SARS-CoV-2, global scientific …

Breast cancer is an uncontrolled growth of breast cells. Among women, breast cancer is the …

Coagulation is the process by which blood changes from a liquid to a gel, forming …

Epigenetics is the study of molecular processes that influence the flow of information between a …

Cancer metabolism has emerged as an important area of research in recent years. Reprogramming of …

The TargetMol’s Hematopoietic Toxicity Compound Library is a focused collection of 104 compounds with defined …

AMPK(Adenosine 5‘-monophosphate (AMP)-activated protein kinase) plays a major role in regulating cellular energy balance by …

Cell signalingis part of any communication process that governs basic activities of cells and coordinates …

In biochemistry, a kinase is an enzyme that catalyzes the transfer of phosphate groups from …

Aging is a natural process of becoming older. The causes of aging are assigned to …

The endoplasmic reticulum (ER) is the cellular organelle that is critical for protein folding and …

An infection happens when a foreign organism enters a person's body and causes harm. These …

Cell signaling is part of any communication process that governs basic activities of cells and …

Diabetes is a chronic, metabolic disease characterized by elevated levels of blood glucose (or blood …

Oxidation-Reduction Compound Library contains 453 compounds with defined prooxidant or antioxidant activity, including a variety …

Most viral mRNAs possess a 5'-terminal cap structure (m7GpppN) which is essential for efficient splicing, …

Autophagy is the natural, regulated mechanism of the cell that disassembles unnecessary or dysfunctional components. …

Traditional de novo drug discovery and development involves an HTS campaign for de novo candidate …

Obesity has become the public health issue of the day-and for good reason. The data …

RdRp (Nsp12), a conserved protein in coronavirus, is an RNA-dependent RNA polymerase (RdRp) and the …

Antibiotics are used to treat or prevent bacterial infections, and sometimes protozoan infections, having saved …

Protease inhibitors are molecules that inhibit the function of proteases (enzymes that aid the breakdown …

Methylation is an important way of protein and nucleic acid modification that regulates gene expression …

Ubiquitination involves covalent attachment of ubiquitin, a small 8-kDa protein, to a substrate and results …