Antimicotici
Gli antifungini sono composti specificamente progettati per fermare, prevenire ed eliminare la crescita dei funghi. In questa categoria, troverete una vasta gamma di agenti antifungini essenziali per la ricerca e le applicazioni terapeutiche. Questi composti sono cruciali nel trattamento delle infezioni fungine e nella prevenzione delle loro recidive, rendendoli strumenti vitali sia in ambito medico che agricolo. Ricercatori e professionisti della salute possono esplorare numerosi antifungini per comprendere i loro meccanismi, ottimizzarne l'efficacia e sviluppare nuovi trattamenti per combattere ceppi fungini resistenti. L'ampia selezione di antifungini supporta i continui progressi nella ricerca sui funghi e lo sviluppo di terapie antifungine efficaci.
Trovati 835 prodotti di "Antimicotici"
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Complex III-IN-1
<p>Complex III-IN-1 inhibits complex III, has antifungal properties, and an EC50 of 18.53 mg/L against S. sclerotiorum.</p>Formula:C14H20ClNO2S2Colore e forma:SolidPeso molecolare:333.9Benzohydroxamic acid
CAS:<p>Benzohydroxamic acid (BHA) is a chitin deacetylase (CDA) inhibitor with notable antifungal properties. It displays Ki values of 8.31 μM against Verticillium dahliae CDA and 9.83 μM against Puccinia striiformis f. sp. tritici CDA. BHA can restore the defense responses in infected host plants by upregulating the expression of defense-related genes, thereby reducing fungal growth and proliferation within the plants. It is applicable in the research of agricultural fungal diseases, such as cotton wilt and wheat stripe rust, caused by pathogens like Verticillium dahliae and Puccinia striiformis.</p>Formula:C7H7NO2Colore e forma:SolidPeso molecolare:137.136A25822B
CAS:<p>A25822B is an antifungal agent.</p>Formula:C28H45NOPurezza:98%Colore e forma:SolidPeso molecolare:411.66GW461484A
CAS:<p>GW461484A is a small molecule inhibitor targeting Candida albicans Yck2, exhibiting an IC50 of 0.11 µM. It has a MIC80 of 12.5 µM against C. albicans. GW461484A shows potential for research into fungal diseases, including drug-resistant Candida infections.</p>Formula:C19H14FN3Colore e forma:SolidPeso molecolare:303.333Antifungal agent 39
CAS:<p>Antifungal agent 39 (Compound 9h) is a broad-spectrum antifungal agent.</p>Formula:C23H22ClN3O5Colore e forma:SolidPeso molecolare:455.89Ethaboxam
CAS:<p>Ethaboxam is a β-tubulin inhibitor and antifungal agent used against oomycete pathogens.</p>Formula:C14H16N4OS2Purezza:99.37%Colore e forma:SolidPeso molecolare:320.43Yck2-IN-1
CAS:<p>Yck2-IN-1 (Compound 2a) is an inhibitor of the fungus Candida albicans Yck2. It has an IC50 of approximately 80 nM for Yck2 and an MIC80 of 12.5 µM for C. albicans, demonstrating good metabolic stability [66% remaining in mouse liver microsomes]. In a mouse model with drug-resistant Candida, Yck2-IN-1 significantly reduced fungal load in the kidneys. Yck2-IN-1 shows potential for research in antifungal infection treatments.</p>Formula:C19H11FN4Colore e forma:SolidPeso molecolare:314.316Tenellin
CAS:<p>Tenellin is a fungal metabolite that inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in erythrocytes. Tenellin is cytotoxic to Sf9 and Sf21 insect cells.</p>Formula:C21H23NO5Colore e forma:SolidPeso molecolare:369.41Succinate dehydrogenase-IN-8
CAS:<p>Succinate dehydrogenase-IN-8 (compound i19) is a potent inhibitor of succinate dehydrogenase (SDH). This indanoyl amino acid derivative demonstrates strong antifungal activity in vitro against Rhizoctonia solani (EC50 = 0.1843 mg/L), Botrytis cinerea (EC50 = 0.4829 mg/L), and Sclerotinia sclerotiorum (EC50 = 0.1349 mg/L).</p>Formula:C22H19Cl2F2N5O2Colore e forma:SolidPeso molecolare:494.32Chitin synthase inhibitor 11
<p>Potent CHS inhibitor with an IC50 of 0.10 mM; exhibits broad-spectrum antifungal properties.</p>Formula:C24H24N4O8Colore e forma:SolidPeso molecolare:496.47Antifungal agent 25
<p>Antifungal agent 25: broad-spectrum, stable in vivo, effective against Candida albicans, including fluconazole-resistant strains.</p>Colore e forma:SolidChitin synthase inhibitor 6
<p>Compound 9b inhibits CHS with an IC50 of 0.21 mM; it's a broad-spectrum antifungal, effective against resistant strains.</p>Formula:C24H25N3O6Colore e forma:SolidPeso molecolare:451.47Antifungal agent 42
<p>Antifungal 42 blocks biofilm formation and inhibits C.albicans' CYP51.</p>Formula:C22H20Cl2N4Se2Colore e forma:SolidPeso molecolare:569.25Antifungal agent 40
<p>Antifungal agent 40 blocks C. albicans CYP51 in pocket II, hindering lanosterol demethylase and biofilm growth.</p>Formula:C22H20Cl2N4SeColore e forma:SolidPeso molecolare:490.29PKR-IN-1
CAS:<p>PKR-IN-1 (Compound 5s) is a pyruvate kinase (PK) inhibitor with antifungal properties, exhibiting an EC50 of 0.21 μg/mL against Rhizoctonia solani (R. solani).</p>Formula:C9HCl5N4OS2Colore e forma:SolidPeso molecolare:422.525Antifungal agent 13
CAS:<p>Antifungal agent 13 demonstrates significant antifungal activity against Sclerotinia sclerotiorum, achieving an EC50 of 1.25 mg/L.</p>Formula:C21H16ClF3N4OColore e forma:SolidPeso molecolare:432.83Wikstrol A
CAS:<p>Wikstrol A: antifungal, anti-mitotic, anti-HIV agent with various IC50/MDC values (67.8-131 µM) and deforms P. oryzae mycelia.</p>Formula:C30H22O10Colore e forma:SolidPeso molecolare:542.49Griseofulvic Acid
CAS:<p>Griseofulvic Acid ((±)-Griseofulvic acid) is a metabolite of the antifungal agent Griseofulvin. It induces protein aggregation and tubulin polymerization in cell-free assays.</p>Formula:C16H15ClO6Peso molecolare:338.74Antifungal agent 16
<p>Antifungal agent 16 has antimicrobial activity comparable to that of ciprofloxacin and has higher antifungal activity than fluconazole.</p>Formula:C27H21N5O2SColore e forma:SolidPeso molecolare:479.55Chitin synthase inhibitor 7
<p>Compound 9c, a chitin synthase inhibitor, has an IC50 of 0.37 nM and is useful for studying fungal infections.</p>Formula:C24H25N3O5Colore e forma:SolidPeso molecolare:435.47bc1 Complex-IN-1
CAS:<p>Bc1 Complex-IN-1 (compound 12g) is a potent inhibitor of the bc1 complex, demonstrating fungicidal properties against cucumber downy mildew (CDM).</p>Formula:C16H22N6O5S2Colore e forma:SolidPeso molecolare:442.513Nikkomycin Z
CAS:<p>Nikkomycin Z (Nikkomycin Z from Streptomyces tendae) is a competitive chitin synthase inhibitor.It inhibitor of the growth of filamentous fungi, insects,</p>Formula:C20H25N5O10Purezza:98%Colore e forma:SolidPeso molecolare:495.44SDH-IN-25
CAS:<p>SDH-IN-25 is an SDH inhibitor with an IC50 of 4.82 mg/L, demonstrating broad-spectrum and potent antifungal activity. By binding to SDH amino acid residues (TRP173, TYR58, and ARG43), it mimics the action mode of the commercial fungicide flutolanil. SDH-IN-25 induces changes in hyphal morphology, disrupts respiratory metabolism by binding to complex II, generates reactive oxygen species (ROS), and affects mitochondrial membrane potential (MMP) in hyphae. This compound is utilized in agricultural disease control research.</p>Formula:C19H15BrCl2N2O4Colore e forma:SolidPeso molecolare:486.143ATPase-IN-5
CAS:<p>ATPase-IN-5 (Compound 11) is an antifungal Pma1p (H+ -ATPase) inhibitor (IC50 = 12.7 μM) that inhibits the growth of Candida albicans and Saccharomyces cerevisiae.</p>Formula:C10H10N4O3SPurezza:99.19%Colore e forma:SolidPeso molecolare:266.28Chitin synthase inhibitor 12
<p>Chitin synthase inhibitor 12: potent CHS blocker (IC50: 0.16 mM), broad-spectrum antifungal, effective against resistant strains. Useful in IFI research.</p>Formula:C23H21ClFN3O5Colore e forma:SolidPeso molecolare:473.88(Z)-Lanoconazole
<p>(Z)-Lanoconazole, an imidazole antifungal for dermatophytosis and onychomycosis, inhibits fungal ergosterol production.</p>Formula:C14H10ClN3S2Colore e forma:SolidPeso molecolare:319.83Antifungal agent 19
<p>Antifungal agent 19 shows the potent antifungal activity ( EC 50 = 0.72 μM).</p>Formula:C19H18F4O2Colore e forma:SolidPeso molecolare:354.34Complex III-IN-2
<p>Complex III-IN-2 inhibits complex III, with antifungal EC50: 29.31 mg/L vs R. solani, 29.98 mg/L vs S. sclerotiorum.</p>Formula:C15H21ClN2O2SColore e forma:SolidPeso molecolare:328.86Chitin synthase inhibitor 5
<p>Calpain Inhibitor-2, lipophilic, inhibits calpain; shows anti-proliferative effects on melanoma, PC-3 cells; blocks 80% DU-145 cell invasion.</p>Formula:C23H22BrN3O5Colore e forma:SolidPeso molecolare:500.34N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide
<p>N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide is a Ole1p desaturase inhibitor as well as antifungal agent [1].</p>Formula:C11H9FN4OColore e forma:SolidPeso molecolare:232.21D75-4590
CAS:<p>D75-4590, a β-1,6-Glucan synthetase inhibitor, combats fungal infections by targeting cell walls.</p>Formula:C21H27N5Purezza:98.56% - 98.85%Colore e forma:SolidPeso molecolare:349.474-Hydroxyvoriconazole
CAS:<p>Metabolite of voriconazole; sterol 14?-demethylase inhibitor</p>Purezza:Min. 95%Tetraconazole
CAS:<p>Tetraconazole is an agent of pesticides.</p>Formula:C13H11Cl2F4N3OColore e forma:Liquid ViscousPeso molecolare:372.14Rhizocticin A
CAS:<p>Rhizocticin A is a potential inhibitor of threonine synthase.</p>Formula:C11H22N5O6PPurezza:98%Colore e forma:SolidPeso molecolare:351.3(S,S)-Valifenalate
CAS:<p>(S,S)-Valifenalate is an acylamino acid fungicide and is used to control a wide range of fungi belonging to the class of Oomycetes.</p>Formula:C19H27ClN2O5Colore e forma:SolidPeso molecolare:398.88Ref: TM-T13878
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