Antimicotici

<p>Caulilexin C inhibits hACAT1 and hACAT2 at 100 µg/ml.</p>

Xanthoxylin (Brevifolin) is a borneol and camphor tasting compound and can be found in a number of food items such as fats and oils, herbs and spices,

<p>Pyrimethanil is a strobilurin fungicide belonging to the anilinopyrimidine class.</p>

<p>Pyrimorph is a fungicide with high activity against the plant pathogen Phytophthora capsici.</p>

<p>E1210 (APX001A) is broad-spectrum and orally active antifungal</p>

<p>AN2718, a benzoxaborole, halts fungi protein synthesis by inhibiting LeuRS in molds/yeasts; IC50: 2 μM (A. fumigatus), 4.2 μM (C. albicans).</p>

<p>FR194738 is an inhibitor of squalene epoxidase with an IC50 of 9.8 nM in HepG2 cell homogenates.</p>

<p>Applications (E)-Cyano(methoxyimino)-acetic Acid is a degradation product of Cymoxanil (C988995), which is a fungicide applied as a seed treatment or as a foliar application to the plants to control late blight.<br>References Morrica, P., et al.: J. Agric. Food Chem. 52, 99 (2004); Dhingani, J. C., et al.: J. Pure. App. Microbiol., 6, 1683 (2012); Bakirici, G.T., et al.: Food. Chem., 135, 1901 (2012)<br></p>

<p>Applications Rhein 8-Glucoside has been seen to exhibit cytotoxic and DNA-damaging properties towards tumor and normal human cells. In addition it has been shown to be an inhibitor of PTP1B (Human Protein Tyrosine Kinase 1B) in vitro. It is an analog of Rhein (R318500) which is found in the free state and as glucoside in Rheum spp, Polygonaceae (rhubarb) and in Senna leaves. It is a potential antioxidant resource: endophytic fungi from medicinal plants.<br>References Wanitschke, Pharmacology, 20, Suppl. 1, 21 (1980); Raimondi, L., et al.: Pharmacol. Res. Commun., 14, 103 (1982); Franchi-Micheli, S., et al.: J. Pharm. Pharmacol., 35, 262 (1983); Li, S. et al.: J. Asian Nat. Prod. Res., 8, 281 (2006); Shi, Y.Q. et al.: Anticancer. Res., 21, 2847 (2001);<br></p>

<p>Applications Methyl 2-Cyano-2-oximinoacetate is an intermediate in synthesizing 2-Cyano-2-(methoxyimino)acetic Acid (C989423), which is a cyano-oxime derivative used as a fungicide.<br>References Tellier, F., et al.: Pestic Biochem Physiol., 78, 151-160 (2004)<br></p>

<p>Applications Potassium Pentathionate Sesquihydrate is potassium salt of Pentathionic acid which is the fungicidal factor of sulfur..<br>References Young, H., et al.: Science, 67, 19 (1928)<br></p>

<p>Applications An Cysteine prodrug, protective aginst the fungal T-2 toxin. It is also a precursor to pharmaceuticals used in the treatment of cataracts.<br>References Shirota, F., et al.: Biochem. Pharmacol., 43, 916 (1992), Wlodek, L., et al.: Int. J. Biochem., 25, 107 (1993), Rathbun, W., et al.: Biochem. Pharmacol., 51, 1111 (1996),<br></p>

<p>Penthiopyrad (MTF-753) shows a broad spectrum of antifungal activity and suppresses fungal respiration.</p>

<p>α-Santalol: antibacterial, antioxidant, anti-tumor, antimitotic, and antifungal against Trichophyton rubrum.</p>

<p>Applications Alamethicin is a peptide antibiotic, produced by the fungus Trichoderma viride. Alamethicin contains the non-proteinogenic amino acid 2-aminoisobutyric acid (Aib), which strongly induces helical peptide structures. In cell membranes, it forms voltage-dependent ion channels by aggregation of four to six molecules.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Afonin, S., et al.: Chembiochem., 4, 1151 (2003), Henriques, S., et al.: Biochem. J., 399, 1 (2006), Almeida, P., et al.: Biochemistry, 48, 8083 (2009), Heitz, F., et al.: Br. J. Pharmacol., 157, 195 (2009),<br></p>

<p>Applications Used in the synthesis of new 5-nitroimidazoles as potential antibacterial drugs via VNS procedure.<br>References Cudmore, S., et al.: Clin. Microbiol. Rev., 17, 783 (2004), Upcroft, J., et al.: Antimicrob. Agents Chemother., 50, 344 (2006),<br></p>

<p>Applications Cyrene is a novel bio-based green solvent used in polymerization reactions. Byproduct in the synthesis of levoglucosenone fungicidal agent.<br>References Sharipov, B. et al.: Chem. Hetero. Comp., 55, 31 (2019); Marino, T. et al.: J. Membrane Sci., 580, 224 (2019);<br></p>