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Antimicotici

Antimicotici

Gli antifungini sono composti specificamente progettati per fermare, prevenire ed eliminare la crescita dei funghi. In questa categoria, troverete una vasta gamma di agenti antifungini essenziali per la ricerca e le applicazioni terapeutiche. Questi composti sono cruciali nel trattamento delle infezioni fungine e nella prevenzione delle loro recidive, rendendoli strumenti vitali sia in ambito medico che agricolo. Ricercatori e professionisti della salute possono esplorare numerosi antifungini per comprendere i loro meccanismi, ottimizzarne l'efficacia e sviluppare nuovi trattamenti per combattere ceppi fungini resistenti. L'ampia selezione di antifungini supporta i continui progressi nella ricerca sui funghi e lo sviluppo di terapie antifungine efficaci.

Trovati 835 prodotti di "Antimicotici"

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  • Complex III-IN-1


    <p>Complex III-IN-1 inhibits complex III, has antifungal properties, and an EC50 of 18.53 mg/L against S. sclerotiorum.</p>
    Formula:C14H20ClNO2S2
    Colore e forma:Solid
    Peso molecolare:333.9
  • Benzohydroxamic acid

    CAS:
    <p>Benzohydroxamic acid (BHA) is a chitin deacetylase (CDA) inhibitor with notable antifungal properties. It displays Ki values of 8.31 μM against Verticillium dahliae CDA and 9.83 μM against Puccinia striiformis f. sp. tritici CDA. BHA can restore the defense responses in infected host plants by upregulating the expression of defense-related genes, thereby reducing fungal growth and proliferation within the plants. It is applicable in the research of agricultural fungal diseases, such as cotton wilt and wheat stripe rust, caused by pathogens like Verticillium dahliae and Puccinia striiformis.</p>
    Formula:C7H7NO2
    Colore e forma:Solid
    Peso molecolare:137.136
  • A25822B

    CAS:
    <p>A25822B is an antifungal agent.</p>
    Formula:C28H45NO
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:411.66
  • GW461484A

    CAS:
    <p>GW461484A is a small molecule inhibitor targeting Candida albicans Yck2, exhibiting an IC50 of 0.11 µM. It has a MIC80 of 12.5 µM against C. albicans. GW461484A shows potential for research into fungal diseases, including drug-resistant Candida infections.</p>
    Formula:C19H14FN3
    Colore e forma:Solid
    Peso molecolare:303.333
  • Antifungal agent 39

    CAS:
    <p>Antifungal agent 39 (Compound 9h) is a broad-spectrum antifungal agent.</p>
    Formula:C23H22ClN3O5
    Colore e forma:Solid
    Peso molecolare:455.89
  • Ethaboxam

    CAS:
    <p>Ethaboxam is a β-tubulin inhibitor and antifungal agent used against oomycete pathogens.</p>
    Formula:C14H16N4OS2
    Purezza:99.37%
    Colore e forma:Solid
    Peso molecolare:320.43
  • Yck2-IN-1

    CAS:
    <p>Yck2-IN-1 (Compound 2a) is an inhibitor of the fungus Candida albicans Yck2. It has an IC50 of approximately 80 nM for Yck2 and an MIC80 of 12.5 µM for C. albicans, demonstrating good metabolic stability [66% remaining in mouse liver microsomes]. In a mouse model with drug-resistant Candida, Yck2-IN-1 significantly reduced fungal load in the kidneys. Yck2-IN-1 shows potential for research in antifungal infection treatments.</p>
    Formula:C19H11FN4
    Colore e forma:Solid
    Peso molecolare:314.316
  • Tenellin

    CAS:
    <p>Tenellin is a fungal metabolite that inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in erythrocytes. Tenellin is cytotoxic to Sf9 and Sf21 insect cells.</p>
    Formula:C21H23NO5
    Colore e forma:Solid
    Peso molecolare:369.41
  • Succinate dehydrogenase-IN-8

    CAS:
    <p>Succinate dehydrogenase-IN-8 (compound i19) is a potent inhibitor of succinate dehydrogenase (SDH). This indanoyl amino acid derivative demonstrates strong antifungal activity in vitro against Rhizoctonia solani (EC50 = 0.1843 mg/L), Botrytis cinerea (EC50 = 0.4829 mg/L), and Sclerotinia sclerotiorum (EC50 = 0.1349 mg/L).</p>
    Formula:C22H19Cl2F2N5O2
    Colore e forma:Solid
    Peso molecolare:494.32
  • Chitin synthase inhibitor 11


    <p>Potent CHS inhibitor with an IC50 of 0.10 mM; exhibits broad-spectrum antifungal properties.</p>
    Formula:C24H24N4O8
    Colore e forma:Solid
    Peso molecolare:496.47
  • Antifungal agent 25


    <p>Antifungal agent 25: broad-spectrum, stable in vivo, effective against Candida albicans, including fluconazole-resistant strains.</p>
    Colore e forma:Solid
  • Chitin synthase inhibitor 6


    <p>Compound 9b inhibits CHS with an IC50 of 0.21 mM; it's a broad-spectrum antifungal, effective against resistant strains.</p>
    Formula:C24H25N3O6
    Colore e forma:Solid
    Peso molecolare:451.47
  • Antifungal agent 42


    <p>Antifungal 42 blocks biofilm formation and inhibits C.albicans' CYP51.</p>
    Formula:C22H20Cl2N4Se2
    Colore e forma:Solid
    Peso molecolare:569.25
  • Antifungal agent 40


    <p>Antifungal agent 40 blocks C. albicans CYP51 in pocket II, hindering lanosterol demethylase and biofilm growth.</p>
    Formula:C22H20Cl2N4Se
    Colore e forma:Solid
    Peso molecolare:490.29
  • PKR-IN-1

    CAS:
    <p>PKR-IN-1 (Compound 5s) is a pyruvate kinase (PK) inhibitor with antifungal properties, exhibiting an EC50 of 0.21 μg/mL against Rhizoctonia solani (R. solani).</p>
    Formula:C9HCl5N4OS2
    Colore e forma:Solid
    Peso molecolare:422.525
  • Antifungal agent 13

    CAS:
    <p>Antifungal agent 13 demonstrates significant antifungal activity against Sclerotinia sclerotiorum, achieving an EC50 of 1.25 mg/L.</p>
    Formula:C21H16ClF3N4O
    Colore e forma:Solid
    Peso molecolare:432.83
  • Wikstrol A

    CAS:
    <p>Wikstrol A: antifungal, anti-mitotic, anti-HIV agent with various IC50/MDC values (67.8-131 µM) and deforms P. oryzae mycelia.</p>
    Formula:C30H22O10
    Colore e forma:Solid
    Peso molecolare:542.49
  • Griseofulvic Acid

    CAS:
    <p>Griseofulvic Acid ((±)-Griseofulvic acid) is a metabolite of the antifungal agent Griseofulvin. It induces protein aggregation and tubulin polymerization in cell-free assays.</p>
    Formula:C16H15ClO6
    Peso molecolare:338.74
  • Antifungal agent 16


    <p>Antifungal agent 16 has antimicrobial activity comparable to that of ciprofloxacin and has higher antifungal activity than fluconazole.</p>
    Formula:C27H21N5O2S
    Colore e forma:Solid
    Peso molecolare:479.55
  • Chitin synthase inhibitor 7


    <p>Compound 9c, a chitin synthase inhibitor, has an IC50 of 0.37 nM and is useful for studying fungal infections.</p>
    Formula:C24H25N3O5
    Colore e forma:Solid
    Peso molecolare:435.47