Antimicotici
Gli antifungini sono composti specificamente progettati per fermare, prevenire ed eliminare la crescita dei funghi. In questa categoria, troverete una vasta gamma di agenti antifungini essenziali per la ricerca e le applicazioni terapeutiche. Questi composti sono cruciali nel trattamento delle infezioni fungine e nella prevenzione delle loro recidive, rendendoli strumenti vitali sia in ambito medico che agricolo. Ricercatori e professionisti della salute possono esplorare numerosi antifungini per comprendere i loro meccanismi, ottimizzarne l'efficacia e sviluppare nuovi trattamenti per combattere ceppi fungini resistenti. L'ampia selezione di antifungini supporta i continui progressi nella ricerca sui funghi e lo sviluppo di terapie antifungine efficaci.
Trovati 837 prodotti di "Antimicotici"
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Nikkomycin Z
CAS:<p>Nikkomycin Z (Nikkomycin Z from Streptomyces tendae) is a competitive chitin synthase inhibitor.It inhibitor of the growth of filamentous fungi, insects,</p>Formula:C20H25N5O10Purezza:98%Colore e forma:SolidPeso molecolare:495.44ATPase-IN-5
CAS:<p>ATPase-IN-5 (Compound 11) is an antifungal Pma1p (H+ -ATPase) inhibitor (IC50 = 12.7 μM) that inhibits the growth of Candida albicans and Saccharomyces cerevisiae.</p>Formula:C10H10N4O3SPurezza:99.19%Colore e forma:SolidPeso molecolare:266.28A25822B
CAS:<p>A25822B is an antifungal agent.</p>Formula:C28H45NOPurezza:98%Colore e forma:SolidPeso molecolare:411.66Chitin synthase inhibitor 12
<p>Chitin synthase inhibitor 12: potent CHS blocker (IC50: 0.16 mM), broad-spectrum antifungal, effective against resistant strains. Useful in IFI research.</p>Formula:C23H21ClFN3O5Colore e forma:SolidPeso molecolare:473.88GW461484A
CAS:<p>GW461484A is a small molecule inhibitor targeting Candida albicans Yck2, exhibiting an IC50 of 0.11 µM. It has a MIC80 of 12.5 µM against C. albicans. GW461484A shows potential for research into fungal diseases, including drug-resistant Candida infections.</p>Formula:C19H14FN3Colore e forma:SolidPeso molecolare:303.333Chitin synthase inhibitor 8
<p>Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal effects that can be used in studies related to fungal infections</p>Formula:C23H23N3O5Colore e forma:SolidPeso molecolare:421.45Succinate dehydrogenase-IN-8
CAS:<p>Succinate dehydrogenase-IN-8 (compound i19) is a potent inhibitor of succinate dehydrogenase (SDH). This indanoyl amino acid derivative demonstrates strong antifungal activity in vitro against Rhizoctonia solani (EC50 = 0.1843 mg/L), Botrytis cinerea (EC50 = 0.4829 mg/L), and Sclerotinia sclerotiorum (EC50 = 0.1349 mg/L).</p>Formula:C22H19Cl2F2N5O2Colore e forma:SolidPeso molecolare:494.32Chitin synthase inhibitor 11
<p>Potent CHS inhibitor with an IC50 of 0.10 mM; exhibits broad-spectrum antifungal properties.</p>Formula:C24H24N4O8Colore e forma:SolidPeso molecolare:496.47Wikstrol A
CAS:<p>Wikstrol A: antifungal, anti-mitotic, anti-HIV agent with various IC50/MDC values (67.8-131 µM) and deforms P. oryzae mycelia.</p>Formula:C30H22O10Colore e forma:SolidPeso molecolare:542.49Antifungal agent 13
CAS:<p>Antifungal agent 13 demonstrates significant antifungal activity against Sclerotinia sclerotiorum, achieving an EC50 of 1.25 mg/L.</p>Formula:C21H16ClF3N4OColore e forma:SolidPeso molecolare:432.83Chitin synthase inhibitor 9
<p>CHS inhibitor 9: a broad-spectrum antifungal for studying fungal infections.</p>Formula:C24H25N3O6Colore e forma:SolidPeso molecolare:451.47WQ3810 TFA
<p>WQ3810 TFA is an orally available fluoroquinolone with antimicrobial activity against Mycobacterium tuberculosis and inhibits the DNA rotamase activity of</p>Formula:C24H23F6N5O5Purezza:99.52%Colore e forma:SoildPeso molecolare:575.46Antifungal agent 40
<p>Antifungal agent 40 blocks C. albicans CYP51 in pocket II, hindering lanosterol demethylase and biofilm growth.</p>Formula:C22H20Cl2N4SeColore e forma:SolidPeso molecolare:490.29Antifungal agent 17
<p>Antifungal agent 17 showed good antifungal activity against B. cinerea (EC50: 2.86 μg/mL).</p>Formula:C18H16Br2O2Colore e forma:SolidPeso molecolare:424.13CDA-IN-1
CAS:<p>CDA-IN-1 (Compound vs#2-1) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal activity. By inhibiting fungal CDA activity, it activates plant immune responses and leads to the accumulation of reactive oxygen species (ROS), hindering fungal growth. At a concentration of 100 μM, CDA-IN-1 achieves inhibition rates of 86.9% on P. xanthii's PxCDA1 and 74.5% on PxCDA2. CDA-IN-1 is applicable in research on fungal plant diseases, such as cucumber powdery mildew and tomato gray mold.</p>Formula:C15H14N2O6Colore e forma:SolidPeso molecolare:318.281SDH-IN-25
CAS:<p>SDH-IN-25 is an SDH inhibitor with an IC50 of 4.82 mg/L, demonstrating broad-spectrum and potent antifungal activity. By binding to SDH amino acid residues (TRP173, TYR58, and ARG43), it mimics the action mode of the commercial fungicide flutolanil. SDH-IN-25 induces changes in hyphal morphology, disrupts respiratory metabolism by binding to complex II, generates reactive oxygen species (ROS), and affects mitochondrial membrane potential (MMP) in hyphae. This compound is utilized in agricultural disease control research.</p>Formula:C19H15BrCl2N2O4Colore e forma:SolidPeso molecolare:486.143Furametpyr
CAS:Furametpyr is a kind of low toxicity pesticides used to control plant diseases caused by various pathogenic microorganisms.Formula:C17H20ClN3O2Purezza:98%Colore e forma:SolidPeso molecolare:333.81Antifungal agent 19
<p>Antifungal agent 19 shows the potent antifungal activity ( EC 50 = 0.72 μM).</p>Formula:C19H18F4O2Colore e forma:SolidPeso molecolare:354.34Tenellin
CAS:<p>Tenellin is a fungal metabolite that inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in erythrocytes. Tenellin is cytotoxic to Sf9 and Sf21 insect cells.</p>Formula:C21H23NO5Colore e forma:SolidPeso molecolare:369.41CDA-IN-2
CAS:<p>CDA-IN-2 (Compound VS#2-3) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal properties. At a concentration of 100 μM, it inhibits P. xanthii's CDAPxCDA1 by 83.7% and PxCDA2 by 74.5%. CDA-IN-2 is applicable in research on agricultural fungal diseases, including resistance to powdery mildew and gray mold.</p>Formula:C17H16N2O7Colore e forma:SolidPeso molecolare:360.318Antifungal agent 125
CAS:<p>Antifungalagent 125 (compound 4H) is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 3.59 μg/mL and exhibits fungicidal activity against Alternaria alternata.</p>Formula:C13H10BrNO4SColore e forma:SolidPeso molecolare:356.192Antifungal agent 12
<p>Antifungal agent 12 is a new fluconazole-like compound that exhibits good antifungal effects.</p>Formula:C20H16F3N7O2S2Colore e forma:SolidPeso molecolare:507.51Antifungal agent 11
<p>Antifungal agent 11 has a good antifungal effect.</p>Formula:C21H19F2N7O3S2Colore e forma:SolidPeso molecolare:519.55Antifungal agent 39
CAS:<p>Antifungal agent 39 (Compound 9h) is a broad-spectrum antifungal agent.</p>Formula:C23H22ClN3O5Colore e forma:SolidPeso molecolare:455.89Yck2-IN-1
CAS:<p>Yck2-IN-1 (Compound 2a) is an inhibitor of the fungus Candida albicans Yck2. It has an IC50 of approximately 80 nM for Yck2 and an MIC80 of 12.5 µM for C. albicans, demonstrating good metabolic stability [66% remaining in mouse liver microsomes]. In a mouse model with drug-resistant Candida, Yck2-IN-1 significantly reduced fungal load in the kidneys. Yck2-IN-1 shows potential for research in antifungal infection treatments.</p>Formula:C19H11FN4Colore e forma:SolidPeso molecolare:314.316Griseofulvic Acid
CAS:<p>Griseofulvic Acid ((±)-Griseofulvic acid) is a metabolite of the antifungal agent Griseofulvin. It induces protein aggregation and tubulin polymerization in cell-free assays.</p>Formula:C16H15ClO6Peso molecolare:338.74Hyalodendrin
CAS:<p>Hyalodendrin ((+)-Hyalodendrin) acts as a fungal growth inhibitor, specifically targeting wood decay fungi. It exhibits low phytotoxicity and possesses an acute toxicity (LD50) level of 75 mg/kg in mice.</p>Formula:C14H16N2O3S2Colore e forma:SolidPeso molecolare:324.42Antibacterial agent 188
CAS:<p>Compound 2d (Antibacterial agent 188) serves as an antibacterial agent that suppresses the activity of dermatophytes [1].</p>Formula:C12H10N4SColore e forma:SolidPeso molecolare:242.3Antifungal agent 42
<p>Antifungal 42 blocks biofilm formation and inhibits C.albicans' CYP51.</p>Formula:C22H20Cl2N4Se2Colore e forma:SolidPeso molecolare:569.25Complex III-IN-1
<p>Complex III-IN-1 inhibits complex III, has antifungal properties, and an EC50 of 18.53 mg/L against S. sclerotiorum.</p>Formula:C14H20ClNO2S2Colore e forma:SolidPeso molecolare:333.9Antifungal agent 100
CAS:<p>Antifungal agent 100 (compound 3i) demonstrates notable antifungal activity, exhibiting an EC 50 of 0.33 mg/L against S. sclerotiorum. It also possesses an IC 50 value of 0.63 mg/mL targeting the Succinate dehydrogenase (SDH) of the same organism [1].</p>Formula:C23H21N3O4SColore e forma:SolidPeso molecolare:435.5bc1 Complex-IN-1
CAS:<p>Bc1 Complex-IN-1 (compound 12g) is a potent inhibitor of the bc1 complex, demonstrating fungicidal properties against cucumber downy mildew (CDM).</p>Formula:C16H22N6O5S2Colore e forma:SolidPeso molecolare:442.513D75-4590
CAS:<p>D75-4590, a β-1,6-Glucan synthetase inhibitor, combats fungal infections by targeting cell walls.</p>Formula:C21H27N5Purezza:98.56% - 98.85%Colore e forma:SolidPeso molecolare:349.474-Hydroxyvoriconazole
CAS:<p>Metabolite of voriconazole; sterol 14?-demethylase inhibitor</p>Purezza:Min. 95%(S,S)-Valifenalate
CAS:<p>(S,S)-Valifenalate is an acylamino acid fungicide and is used to control a wide range of fungi belonging to the class of Oomycetes.</p>Formula:C19H27ClN2O5Colore e forma:SolidPeso molecolare:398.88Tetraconazole
CAS:<p>Tetraconazole is an agent of pesticides.</p>Formula:C13H11Cl2F4N3OColore e forma:Liquid ViscousPeso molecolare:372.14Rhizocticin A
CAS:<p>Rhizocticin A is a potential inhibitor of threonine synthase.</p>Formula:C11H22N5O6PPurezza:98%Colore e forma:SolidPeso molecolare:351.3
