Antimicotici
Gli antifungini sono composti specificamente progettati per fermare, prevenire ed eliminare la crescita dei funghi. In questa categoria, troverete una vasta gamma di agenti antifungini essenziali per la ricerca e le applicazioni terapeutiche. Questi composti sono cruciali nel trattamento delle infezioni fungine e nella prevenzione delle loro recidive, rendendoli strumenti vitali sia in ambito medico che agricolo. Ricercatori e professionisti della salute possono esplorare numerosi antifungini per comprendere i loro meccanismi, ottimizzarne l'efficacia e sviluppare nuovi trattamenti per combattere ceppi fungini resistenti. L'ampia selezione di antifungini supporta i continui progressi nella ricerca sui funghi e lo sviluppo di terapie antifungine efficaci.
Trovati 909 prodotti di "Antimicotici"
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Y18501
CAS:Y18501, an oxysterol-binding protein (OSBPI) inhibitor structurally akin to Oxathiapiprolin, demonstrates potent inhibition against Phytophthora spp.Formula:C27H26F2N6O2SColore e forma:SolidPeso molecolare:536.6Antifungal agent 48
CAS:Antifungal agent 48 (Example 308), active against Cryptococcus neoformans, exhibits a minimum inhibitory concentration (MIC) value of 11 μM [1].Formula:C13H10O4SColore e forma:SolidPeso molecolare:262.28Icofungipen
CAS:Icofungipen is an oral antifungals with active against Candida species.Formula:C7H11NO2Purezza:98%Colore e forma:SolidPeso molecolare:141.17Loflucarban
CAS:Loflucarban (Fluonilid) is an antimycotic compoud.Formula:C13H9Cl2FN2SPurezza:98.08% - 98.15%Colore e forma:SolidPeso molecolare:315.19Antifungal agent 66
CAS:Antifungal agent 66 (compound 10) exhibits broad-spectrum antifungal activity against seven phytopathogenic fungal mycelia and significant inhibitory effects onFormula:C19H25ClO6Colore e forma:SolidPeso molecolare:384.85Laxifloran
CAS:Laxifloran possesses antibacterial and antifungal properties.Formula:C17H18O5Colore e forma:SolidPeso molecolare:302.322-Dodecanol
CAS:2-Dodecanol suppresses both hyphal development and SIR2 gene expression in Candida albicans [1].Formula:C12H26OColore e forma:SolidPeso molecolare:186.33Antifungal agent 26
CAS:Pradimicin A derivative 26 exhibits antifungal, antiviral, and antiparasitic properties by attaching to d-mannose (Man)-rich glycans in pathogenic organisms [1Formula:C40H45N3O18Colore e forma:SolidPeso molecolare:855.79Antifungal agent 49
CAS:Antifungal agent 49 (Example 112) exhibits activity against Cryptococcus neoformans, demonstrating a minimum inhibitory concentration (MIC) of 49 μM [1].Formula:C15H12O4Colore e forma:SolidPeso molecolare:256.25Eucalyptacid A
CAS:Eucalyptacid A, a metabolite with antifungal properties, demonstrates efficacy against Alternaria solani, displaying minimum inhibitory concentrations (MIC)Formula:C17H32O5Colore e forma:SolidPeso molecolare:316.43TMTD (Tetramethylthiuram disulfide)
CAS:TMTD (Tetramethylthiuram disulfide) reduces the growth performance of chickens by reducing liver index, while increasing kidney, heart and spleen index. In addition, TMTD also induces tibial chondrodysplasia (TD) by regulating the expression of VEGF, HIF-1α and WNT4. As a super accelerator in rubber processing, TMTD plays an important role in the low-temperature vulcanization process and is a key pesticide in agriculture.Formula:C6H12N2S4Colore e forma:SolidPeso molecolare:240.43Orysastrobin
CAS:Orysastrobin, a "quinone outside inhibitor" (QoI) fungicide, demonstrates outstanding efficacy in controlling rice leaf and panicle blast as well as sheathFormula:C18H25N5O5Colore e forma:SolidPeso molecolare:391.42PF-184563
CAS:PF-184563 is an effective and selective non-peptide antagonist of the V1a receptor with oral activity, suitable for studying Raynaud's disease dysmenorrhoea.Formula:C21H23ClN6Purezza:99.67%Colore e forma:SolidPeso molecolare:394.9Antifungal agent 24
CAS:<p>Antifungal agent 24 (Compound 6) is an antifungal agent that inhibits Candida albicans (MIC: 0.03 μg/ml).</p>Formula:C24H18F2N4OColore e forma:SolidPeso molecolare:416.42TMV-IN-5
CAS:<p>TMV-IN-5 (compound 1a) serves as an antiviral/antifungal agent, specifically targeting and inhibiting the assembly of the tobacco mosaic virus (TMV) by binding</p>Formula:C22H23N3SColore e forma:SolidPeso molecolare:361.5Antiproliferative agent-33
CAS:Antiproliferative Agent-33 (Compound 2g) serves as an anti-proliferative, antifungal, and antibacterial agent, effectively inhibiting the proliferation of MDA-Formula:C21H26N2OColore e forma:SolidPeso molecolare:322.44Methyl 3,4-dimethoxycinnamate
CAS:Methyl 3,4-dimethoxycinnamate impedes uredospore germination and concurrently inhibits global DNA methylation in Hep3B cells [1] [2].Formula:C12H14O4Colore e forma:SolidPeso molecolare:222.24Prochloraz manganese
CAS:Prochloraz manganese, an antifungal agent utilized in the agricultural sectors [1], serves to protect crops by inhibiting fungal growth.Formula:C60H64Cl14MnN12O8Colore e forma:SolidPeso molecolare:1632.51Alteconazole
CAS:Alteconazole is an antifungal drug.Formula:C17H12Cl3N3OPurezza:98%Colore e forma:SolidPeso molecolare:380.66VT-1598
CAS:VT-1598 is a novel, selective, orally active fungal CYP51 inhibitor. VT-1598 exhibits antifungal effects against Candida albicans.Formula:C31H20F4N6O2Colore e forma:SolidPeso molecolare:584.52Azaconazole
CAS:Azaconazole, an agricultural fungicide, is used for controlling powdery mildew on crops and bean rust.Formula:C12H11Cl2N3O2Colore e forma:SolidPeso molecolare:300.146-Chloro-7-deazapurine-β-D-riboside
CAS:6-Chloro-7-deazapurine-β-D-riboside shows antifungal activity.Formula:C11H12ClN3O4Purezza:98.26%Colore e forma:SolidPeso molecolare:285.68N,O-Diacetyltyramine
CAS:N,O-Diacetyltyramine, isolated from the actinomycete Pseudonocardia endophytica VUK-10, exhibits both antibacterial activity against Gram-positive and Gram-negative bacteria, alongside fungi, and demonstrates cytotoxicity towards MDA-MB-231, HeLa, MCF-7, and OAW-42 cells [1].Formula:C12H15NO3Colore e forma:SolidPeso molecolare:221.25APX001
CAS:APX001 is a prodrug of APX-001A. APX001 is the first-in-class inhibitor of the fungal protein Gwt1.Formula:C22H21N4O6PPurezza:98%Colore e forma:SolidPeso molecolare:468.42-C-methylene-myo-inositol oxide
CAS:2-C-Methylene-myo-inositol oxide (NSC 45109), an inositol derivative, promotes pseudohyphal growth in Saccharomyces species [1].Formula:C7H12O6Colore e forma:SolidPeso molecolare:192.17Chitin synthase inhibitor 14
CAS:Chitin Synthase Inhibitor 14 (compound 4n), a potent chitin synthase (CHS) inhibitor, exhibits antifungal activity and is effective against drug-resistantFormula:C25H26ClN5O5Colore e forma:SolidPeso molecolare:511.96Inz-1
CAS:Inz-1 is an effective and fungal-selective inhibitor of mitochondrial cytochrome bc1 with IC50s of 8.092 and 45.320 μM for yeast and human.Formula:C16H14N2O2Purezza:99.55% - 99.88%Colore e forma:SolidPeso molecolare:266.29Fenpropidin
CAS:Fenpropidin (Ro-12-3049), a fungicide, is a specific inhibitor of sterol 14-reductase and biosynthesis.Formula:C19H31NPurezza:98.58% - 99.54%Colore e forma:SolidPeso molecolare:273.46Antiproliferative agent-18
CAS:Compound 5k (Antiproliferative Agent-18) is an antiproliferative agent that exhibits moderate antibacterial and antifungal activities [1].Formula:C26H27FN2OSColore e forma:SolidPeso molecolare:434.57Byssochlamic Acid
CAS:Byssochlamic acid, a mycotoxin identified in the agricultural fungal pathogen B. fulva, exhibits lethality in mice with an LD50 of 94 mg/kg.Formula:C18H20O6Colore e forma:SolidPeso molecolare:332.4MoTPS1-IN-1
CAS:MoTPS1-IN-1 is a potent MoTPS1 inhibitor with antifungal anti-inflammatory activity that acts through interaction with Glu396 study ulcerative colitis.Formula:C23H27F3N2O4Purezza:99.76%Colore e forma:SoildPeso molecolare:452.47FR194738 free base
CAS:FR194738 free base inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM.Formula:C27H37NO2SPurezza:99.13%Colore e forma:SolidPeso molecolare:439.65Ref: TM-T11321
1mg90,00€5mg170,00€10mg248,00€25mg386,00€50mg520,00€100mg672,00€1mL*10mM (DMSO)187,00€HDAC/HSP90-IN-3
CAS:HDAC/HSP90-IN-3, a dual inhibitor targeting fungal Hsp90 (IC50: 0.83 μM) & HDAC (IC50: 0.91 μM), counters azole-resistant C. albicans.Formula:C26H33N5O6Colore e forma:SolidPeso molecolare:511.57Inz-5
CAS:Inz-5 is a fungal-selective inhibitor of mitochondrial cytochrome bc1. Inz-5 impairs fungal virulence. It also prevents the evolution of drug resistance.Formula:C18H14F4N6Colore e forma:SolidPeso molecolare:390.34Zoxamide
CAS:Zoxamide (RH-7281) is an oomycete-specific fungicide that impedes nuclear division in Phytophthora capsici germlings and disrupts the microtubule cytoskeleton [Formula:C14H16Cl3NO2Colore e forma:SolidPeso molecolare:336.64APX2039
CAS:APX2039 is an orally active fungal Gwt1 enzyme inhibitor and a prodrug of the novel Gwt2096 inhibitor APX1.APX2039 exhibits potent anti-Kryptococcal activityFormula:C20H15FN4O2Purezza:98.72% - 99.07%Colore e forma:SolidPeso molecolare:362.36Ref: TM-T61355
1mg123,00€5mg274,00€10mg411,00€25mg725,00€50mg1.035,00€100mg1.425,00€200mg1.882,00€1mL*10mM (DMSO)304,00€Econazole
CAS:<p>Econazole is an imidazole antifungal agent with action on fungal cell membrane disruption and is used for treating fungal skin infections like athlete's foot and ringworm.</p>Formula:C18H15Cl3N2OPurezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:381.68 g/mol2,4′-Dichloroacetanilide
CAS:2,4′-Dichloroacetanilide (2-chloro-N-(4-chlorophenyl)acetamide) has antifungal activity and inhibits T. asteroides with a MIC value of 6.25 μg/mL.Formula:C8H7Cl2NOPurezza:99.36%Colore e forma:SolidPeso molecolare:204.05Fengycin
CAS:Fengycin is a cyclic lipopeptide from Bacillus subtilis acts as a biosurfactant and antifungal. As a fungicide, it has a mode of action that involves the formation of ion channels in the fungal lipid membrane, leading to membrane leakage This activity is negatively correlated to cholesterol levels, and may explain why mammalian cells, with higher cholesterol present, are not sensitive to fengycin.Formula:C72H110N12O20Purezza:Min. 90 Area-%Colore e forma:PowderPeso molecolare:1,463.71 g/molAntifungal agent 28
Antifungal 28 disrupts Candida, hits fluconazole-resistant strains, and inhibits biofilms.Formula:C22H29N5OSColore e forma:SolidPeso molecolare:411.56Antifungal agent 127
CAS:Antifungalagent 127 (Compound 6c) is an antifungal agent with potent inhibitory activity against Botrytis cinerea and Rhizoctonia solani.Formula:C13H12ClN3OColore e forma:SolidPeso molecolare:261.707CDA-IN-1
CAS:CDA-IN-1 (Compound vs#2-1) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal activity. By inhibiting fungal CDA activity, it activates plant immune responses and leads to the accumulation of reactive oxygen species (ROS), hindering fungal growth. At a concentration of 100 μM, CDA-IN-1 achieves inhibition rates of 86.9% on P. xanthii's PxCDA1 and 74.5% on PxCDA2. CDA-IN-1 is applicable in research on fungal plant diseases, such as cucumber powdery mildew and tomato gray mold.Formula:C15H14N2O6Colore e forma:SolidPeso molecolare:318.281Antifungal agent 19
Antifungal agent 19 shows the potent antifungal activity ( EC 50 = 0.72 μM).Formula:C19H18F4O2Colore e forma:SolidPeso molecolare:354.34Antifungal agent 134
CAS:Antifungalagent 134 (Compound B13) is an antifungal agent effective against Botrytis cinerea, Alternaria solani, Fusarium graminearum, Rhizoctonia solani, Colletotrichum orbiculare, and Alternaria alternata with EC50 values of 3.24, 1.89, 1.70, 0.36, 4.27, and 1.50 μg/mL, respectively. It disrupts the fungal cell membranes and mitochondria, leading to substantial accumulation of reactive oxygen species (ROS). Additionally, Antifungalagent 134 exhibits significant herbicidal activity on field weeds such as Amaranthus retroflexus L and Abutilon theophrasti Medicus, and is applicable in crop disease and field weed research.Formula:C18H12F4N2O4Colore e forma:SolidPeso molecolare:396.29HDAC-IN-87
CAS:HDAC-IN-87 (Compound XII6) is a non-selective HDAC inhibitor with pIC50 values of 6.9 for HDAC4 and 5.8 for HDAC6. It exhibits fungicidal activity against P. sorghi and P. pachyrhizi. The acute oral LD50 in both male and female rats is greater than 500 mg/kg.Formula:C13H7F5N4O2SColore e forma:SolidPeso molecolare:378.277Antifungal agent 43
Antifungal agent 43 inhibits biofilms with low toxicity to human cancer cells.Formula:C24H26N4Se2Colore e forma:SolidPeso molecolare:528.41N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide
N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide is a Ole1p desaturase inhibitor as well as antifungal agent [1].Formula:C11H9FN4OColore e forma:SolidPeso molecolare:232.21Pyriofenone
CAS:Pyriofenone (IKF-309) is an aryl phenyl ketone fungicide predominantly used to control powdery mildew on crops such as cereals, rice, fruit trees, and vegetables. It exhibits moderate efficacy against rice blast disease. Pyriofenone functions through prevention, residue activity, treatment, rainfastness, translaminar action, and fumigation.Formula:C18H20ClNO5Colore e forma:SolidPeso molecolare:365.81Hyalodendrin
CAS:Hyalodendrin ((+)-Hyalodendrin) acts as a fungal growth inhibitor, specifically targeting wood decay fungi. It exhibits low phytotoxicity and possesses an acute toxicity (LD50) level of 75 mg/kg in mice.Formula:C14H16N2O3S2Colore e forma:SolidPeso molecolare:324.42Antifungal agent 13
CAS:Antifungal agent 13 demonstrates significant antifungal activity against Sclerotinia sclerotiorum, achieving an EC50 of 1.25 mg/L.Formula:C21H16ClF3N4OColore e forma:SolidPeso molecolare:432.83Chitin synthase inhibitor 6
Compound 9b inhibits CHS with an IC50 of 0.21 mM; it's a broad-spectrum antifungal, effective against resistant strains.Formula:C24H25N3O6Colore e forma:SolidPeso molecolare:451.47Antifungal agent 25
Antifungal agent 25: broad-spectrum, stable in vivo, effective against Candida albicans, including fluconazole-resistant strains.Colore e forma:SolidAntifungal agent 16
Antifungal agent 16 has antimicrobial activity comparable to that of ciprofloxacin and has higher antifungal activity than fluconazole.Formula:C27H21N5O2SColore e forma:SolidPeso molecolare:479.55Succinate dehydrogenase-IN-8
CAS:Succinate dehydrogenase-IN-8 (compound i19) is a potent inhibitor of succinate dehydrogenase (SDH). This indanoyl amino acid derivative demonstrates strong antifungal activity in vitro against Rhizoctonia solani (EC50 = 0.1843 mg/L), Botrytis cinerea (EC50 = 0.4829 mg/L), and Sclerotinia sclerotiorum (EC50 = 0.1349 mg/L).Formula:C22H19Cl2F2N5O2Colore e forma:SolidPeso molecolare:494.32Tenellin
CAS:Tenellin is a fungal metabolite that inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in erythrocytes. Tenellin is cytotoxic to Sf9 and Sf21 insect cells.Formula:C21H23NO5Colore e forma:SolidPeso molecolare:369.41Complex III-IN-1
Complex III-IN-1 inhibits complex III, has antifungal properties, and an EC50 of 18.53 mg/L against S. sclerotiorum.Formula:C14H20ClNO2S2Colore e forma:SolidPeso molecolare:333.9Yck2-IN-1
CAS:Yck2-IN-1 (Compound 2a) is an inhibitor of the fungus Candida albicans Yck2. It has an IC50 of approximately 80 nM for Yck2 and an MIC80 of 12.5 µM for C. albicans, demonstrating good metabolic stability [66% remaining in mouse liver microsomes]. In a mouse model with drug-resistant Candida, Yck2-IN-1 significantly reduced fungal load in the kidneys. Yck2-IN-1 shows potential for research in antifungal infection treatments.Formula:C19H11FN4Colore e forma:SolidPeso molecolare:314.316CDA-IN-2
CAS:CDA-IN-2 (Compound VS#2-3) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal properties. At a concentration of 100 μM, it inhibits P. xanthii's CDAPxCDA1 by 83.7% and PxCDA2 by 74.5%. CDA-IN-2 is applicable in research on agricultural fungal diseases, including resistance to powdery mildew and gray mold.Formula:C17H16N2O7Colore e forma:SolidPeso molecolare:360.318Isopyrazam
CAS:Isopyrazam, a plant protection product, exhibits potent antifungal activity. When applied to crops, it effectively inhibits the growth of various plant pathogenic fungi, significantly enhancing both the yield and quality of the crops. This compound demonstrates exceptional disease resistance capabilities in agricultural applications.Formula:C20H23F2N3OColore e forma:SolidPeso molecolare:359.41RMG8-8
RMG8-8 shows the excellent efficacy against C. neoformans (1.56 μg/mL).Formula:C41H78N8O5Colore e forma:SolidPeso molecolare:763.11Antifungal agent 12
Antifungal agent 12 is a new fluconazole-like compound that exhibits good antifungal effects.Formula:C20H16F3N7O2S2Colore e forma:SolidPeso molecolare:507.51WQ3810 TFA
WQ3810 TFA is an orally available fluoroquinolone with antimicrobial activity against Mycobacterium tuberculosis and inhibits the DNA rotamase activity ofFormula:C24H23F6N5O5Purezza:99.52%Colore e forma:SoildPeso molecolare:575.46Antifungal agent 42
Antifungal 42 blocks biofilm formation and inhibits C.albicans' CYP51.Formula:C22H20Cl2N4Se2Colore e forma:SolidPeso molecolare:569.25Chitin synthase inhibitor 9
CHS inhibitor 9: a broad-spectrum antifungal for studying fungal infections.Formula:C24H25N3O6Colore e forma:SolidPeso molecolare:451.47Antifungal agent 11
Antifungal agent 11 has a good antifungal effect.Formula:C21H19F2N7O3S2Colore e forma:SolidPeso molecolare:519.55A25822B
CAS:A25822B is an antifungal agent.Formula:C28H45NOPurezza:98%Colore e forma:SolidPeso molecolare:411.66AnCDA-IN-1
CAS:AnCDA-IN-1 (Compound J075-4187) is an inhibitor of chitin deacetylase (CDA) exhibiting antifungal properties. It possesses an IC50 of 4.24 μM against A. nidulans AnCDA. The compound demonstrates a minimum inhibitory concentration (MIC) of 260 μg/mL and a minimum fungicidal concentration (MFC) of 520 μg/mL for food spoilage fungi and plant pathogenic fungi. AnCDA-IN-1 is applicable for research in the antifungal domain.Formula:C16H13ClN4O2Colore e forma:SolidPeso molecolare:328.753Wikstrol A
CAS:Wikstrol A: antifungal, anti-mitotic, anti-HIV agent with various IC50/MDC values (67.8-131 µM) and deforms P. oryzae mycelia.Formula:C30H22O10Colore e forma:SolidPeso molecolare:542.49Complex III-IN-2
Complex III-IN-2 inhibits complex III, with antifungal EC50: 29.31 mg/L vs R. solani, 29.98 mg/L vs S. sclerotiorum.Formula:C15H21ClN2O2SColore e forma:SolidPeso molecolare:328.86(Z)-Lanoconazole
<p>(Z)-Lanoconazole, an imidazole antifungal for dermatophytosis and onychomycosis, inhibits fungal ergosterol production.</p>Formula:C14H10ClN3S2Colore e forma:SolidPeso molecolare:319.83Furametpyr
CAS:Furametpyr is a kind of low toxicity pesticides used to control plant diseases caused by various pathogenic microorganisms.Formula:C17H20ClN3O2Purezza:98%Colore e forma:SolidPeso molecolare:333.81Antifungal agent 40
Antifungal agent 40 blocks C. albicans CYP51 in pocket II, hindering lanosterol demethylase and biofilm growth.Formula:C22H20Cl2N4SeColore e forma:SolidPeso molecolare:490.29Antifungal agent 125
CAS:Antifungalagent 125 (compound 4H) is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 3.59 μg/mL and exhibits fungicidal activity against Alternaria alternata.Formula:C13H10BrNO4SColore e forma:SolidPeso molecolare:356.192Chitin synthase inhibitor 11
Potent CHS inhibitor with an IC50 of 0.10 mM; exhibits broad-spectrum antifungal properties.Formula:C24H24N4O8Colore e forma:SolidPeso molecolare:496.47Chitin synthase inhibitor 5
Calpain Inhibitor-2, lipophilic, inhibits calpain; shows anti-proliferative effects on melanoma, PC-3 cells; blocks 80% DU-145 cell invasion.Formula:C23H22BrN3O5Colore e forma:SolidPeso molecolare:500.34Chitin synthase inhibitor 8
Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal effects that can be used in studies related to fungal infectionsFormula:C23H23N3O5Colore e forma:SolidPeso molecolare:421.45Fosmanogepix
CAS:Fosmanogepix (APX001) is a broad-spectrum oral antifungal that targets Gwt1 enzyme, transforming into active APX001A in the body.Formula:C22H21N4O6PPurezza:98%Colore e forma:SolidPeso molecolare:468.40bc1 Complex-IN-1
CAS:Bc1 Complex-IN-1 (compound 12g) is a potent inhibitor of the bc1 complex, demonstrating fungicidal properties against cucumber downy mildew (CDM).Formula:C16H22N6O5S2Colore e forma:SolidPeso molecolare:442.513Antifungal agent 100
CAS:Antifungal agent 100 (compound 3i) demonstrates notable antifungal activity, exhibiting an EC 50 of 0.33 mg/L against S. sclerotiorum. It also possesses an IC 50 value of 0.63 mg/mL targeting the Succinate dehydrogenase (SDH) of the same organism [1].Formula:C23H21N3O4SColore e forma:SolidPeso molecolare:435.5Chitin synthase inhibitor 12
Chitin synthase inhibitor 12: potent CHS blocker (IC50: 0.16 mM), broad-spectrum antifungal, effective against resistant strains. Useful in IFI research.Formula:C23H21ClFN3O5Colore e forma:SolidPeso molecolare:473.88ATPase-IN-5
CAS:<p>ATPase-IN-5 (Compound 11) is an antifungal Pma1p (H+ -ATPase) inhibitor (IC50 = 12.7 μM) that inhibits the growth of Candida albicans and Saccharomyces cerevisiae.</p>Formula:C10H10N4O3SPurezza:99.19%Colore e forma:SolidPeso molecolare:266.28Ref: TM-T204943
1mg185,00€5mg459,00€10mg657,00€25mg1.026,00€50mg1.415,00€100mg1.872,00€200mg2.555,00€Chitin synthase inhibitor 7
Compound 9c, a chitin synthase inhibitor, has an IC50 of 0.37 nM and is useful for studying fungal infections.Formula:C24H25N3O5Colore e forma:SolidPeso molecolare:435.47CYP51-IN-7
CAS:CYP51-IN-7 (compound 1g) is an analogue of Fluconazole and serves as an effective antifungal agent. It exhibits inhibitory activity against Microsporum gypseum and Candida albicans, with MIC80 values of 62.5 ng/mL and 250 ng/mL, respectively.Formula:C21H21ClF2N4OPeso molecolare:418.87GW461484A
CAS:GW461484A is a small molecule inhibitor targeting Candida albicans Yck2, exhibiting an IC50 of 0.11 µM. It has a MIC80 of 12.5 µM against C. albicans. GW461484A shows potential for research into fungal diseases, including drug-resistant Candida infections.Formula:C19H14FN3Colore e forma:SolidPeso molecolare:303.333Benzohydroxamic acid
CAS:Benzohydroxamic acid (BHA) is a chitin deacetylase (CDA) inhibitor with notable antifungal properties. It displays Ki values of 8.31 μM against Verticillium dahliae CDA and 9.83 μM against Puccinia striiformis f. sp. tritici CDA. BHA can restore the defense responses in infected host plants by upregulating the expression of defense-related genes, thereby reducing fungal growth and proliferation within the plants. It is applicable in the research of agricultural fungal diseases, such as cotton wilt and wheat stripe rust, caused by pathogens like Verticillium dahliae and Puccinia striiformis.Formula:C7H7NO2Colore e forma:SolidPeso molecolare:137.136FDU-PB-22
CAS:FDU-PB-22, a novel synthetic cannabinoid, undergoes rapid metabolism in human liver microsomes (HLM) with a half-life of 12.4 minutes.Formula:C26H18FNO2Colore e forma:SolidPeso molecolare:395.43EGFR-IN-133
CAS:EGFR-IN-133 (Compound 24) serves as an inhibitor targeting various mutations of the EGFR, including the wild type, L858R/T790M, d19/T790M, L858R/T790M/C797S, and d19/T790M/C797S with respective IC50 values of 0.1, 0.044, 0.036, 0.04, and 0.054 nM. The compound exhibits favorable pharmacokinetic properties and high oral bioavailability.Formula:C27H29F2N7O3Colore e forma:SolidPeso molecolare:537.56SDH-IN-25
CAS:<p>SDH-IN-25 is an SDH inhibitor with an IC50 of 4.82 mg/L, demonstrating broad-spectrum and potent antifungal activity. By binding to SDH amino acid residues (TRP173, TYR58, and ARG43), it mimics the action mode of the commercial fungicide flutolanil. SDH-IN-25 induces changes in hyphal morphology, disrupts respiratory metabolism by binding to complex II, generates reactive oxygen species (ROS), and affects mitochondrial membrane potential (MMP) in hyphae. This compound is utilized in agricultural disease control research.</p>Formula:C19H15BrCl2N2O4Colore e forma:SolidPeso molecolare:486.143(3R,6S)-Bassiatin
CAS:(3R,6S)-Bassiatin represents the enantiomeric form of the fungal metabolite known as bassiatin.Formula:C15H19NO3Peso molecolare:261.32Antifungal agent 17
Antifungal agent 17 showed good antifungal activity against B. cinerea (EC50: 2.86 μg/mL).Formula:C18H16Br2O2Colore e forma:SolidPeso molecolare:424.13Ethaboxam
CAS:Ethaboxam is a β-tubulin inhibitor and antifungal agent used against oomycete pathogens.Formula:C14H16N4OS2Purezza:99.37%Colore e forma:SolidPeso molecolare:320.43Ref: TM-T204712
1mg185,00€5mg459,00€10mg657,00€25mg1.026,00€50mg1.415,00€100mg1.872,00€200mg2.555,00€CYP51-IN-14
CAS:CYP51-IN-14 (compound 1n), a derivative of Fluconazole, functions as an effective antifungal agent. This compound inhibits Microsporum gypseum and Candida albicans with a minimum inhibitory concentration (MIC80) of 1 μg/mL.Formula:C21H20Cl2F2N4OPeso molecolare:453.31HSP90-IN-9
HSP90-IN-9: potent HSP90 inhibitor, dose-dependent fungicide, impedes biofilm/morphology with FLC, reverses FLC resistance.Colore e forma:SolidVNI
CAS:VNI is an effective inhibitor of CYP51. It suppresses sterol synthesis in Trypanosoma cruzi, exhibiting anti-Trypanosoma cruzi activity.Formula:C26H19Cl2N5O2Colore e forma:SolidPeso molecolare:504.37Griseofulvic Acid
CAS:Griseofulvic Acid ((±)-Griseofulvic acid) is a metabolite of the antifungal agent Griseofulvin. It induces protein aggregation and tubulin polymerization in cell-free assays.Formula:C16H15ClO6Peso molecolare:338.74Antibacterial agent 188
CAS:Compound 2d (Antibacterial agent 188) serves as an antibacterial agent that suppresses the activity of dermatophytes [1].Formula:C12H10N4SColore e forma:SolidPeso molecolare:242.3CDA-IN-3
CAS:CDA-IN-3 (NCDI) is a chitin deacetylase (CDA) inhibitor with antiparasitic properties. It disrupts chitin metabolism in nematodes, increasing ROS levels within these organisms and causing cellular damage. CDA-IN-3 significantly inhibits all developmental stages of Caenorhabditis elegans and can be utilized in research focused on anti-infective applications.Formula:C16H27N3O3S2Colore e forma:SolidPeso molecolare:373.534Antifungal agent 39
CAS:Antifungal agent 39 (Compound 9h) is a broad-spectrum antifungal agent.Formula:C23H22ClN3O5Colore e forma:SolidPeso molecolare:455.89CDA-IN-4
CAS:CDA-IN-4 (compound VS-24) is an inhibitor of chitin deacetylase (CDA). At a concentration of 100 μg/mL, CDA-IN-4 provides a protective effect of 61.2% against rice blast disease.Formula:C10H9BrN4O2SColore e forma:SolidPeso molecolare:329.17PKR-IN-1
CAS:PKR-IN-1 (Compound 5s) is a pyruvate kinase (PK) inhibitor with antifungal properties, exhibiting an EC50 of 0.21 μg/mL against Rhizoctonia solani (R. solani).Formula:C9HCl5N4OS2Colore e forma:SolidPeso molecolare:422.525SARS-CoV-2 Mpro-IN-34
SARS-CoV-2 Mpro-IN-34 (Compound 26) acts as an inhibitor of SARS-CoV-2 Mpro with an IC50 of 6 nM. It also inhibits OC43 Mpro, demonstrating an IC50 of 33 nM. Furthermore, this compound exhibits antiviral activity in Vero E6 cells infected with SARS-CoV-2, with an EC50 of 0.103 μM.Formula:C30H37Cl2N5O3Colore e forma:SolidPeso molecolare:586.55Nikkomycin Z
CAS:Nikkomycin Z (Nikkomycin Z from Streptomyces tendae) is a competitive chitin synthase inhibitor.It inhibitor of the growth of filamentous fungi, insects,Formula:C20H25N5O10Purezza:98%Colore e forma:SolidPeso molecolare:495.44D75-4590
CAS:<p>D75-4590, a β-1,6-Glucan synthetase inhibitor, combats fungal infections by targeting cell walls.</p>Formula:C21H27N5Purezza:98.56% - 98.85%Colore e forma:SolidPeso molecolare:349.474-Hydroxyvoriconazole
CAS:<p>Metabolite of voriconazole; sterol 14?-demethylase inhibitor</p>Purezza:Min. 95%2,7-Dihydroxynaphthalene
CAS:2,7-Dihydroxynaphthalene is a useful organic compound for research related to life sciences. The catalog number is T67338 and the CAS number is 582-17-2.Formula:C10H8O2Colore e forma:SolidPeso molecolare:160.17Tetraconazole
CAS:Tetraconazole is an agent of pesticides.Formula:C13H11Cl2F4N3OColore e forma:Liquid ViscousPeso molecolare:372.14Rhizocticin A
CAS:Rhizocticin A is a potential inhibitor of threonine synthase.Formula:C11H22N5O6PPurezza:98%Colore e forma:SolidPeso molecolare:351.3Amphotericin A
CAS:<p>Amphotericin A is a polyene macrolide antibiotic, which is derived primarily from the soil bacterium *Streptomyces nodosus*. This compound functions by binding to ergosterol, an essential component of fungal cell membranes. This binding creates pores in the membrane, increasing its permeability and ultimately leading to cell death. Unlike its more widely used counterpart Amphotericin B, Amphotericin A is less frequently utilized but is critical in the study and understanding of antifungal activity.</p>Formula:C47H75NO17Purezza:Min. 95%Peso molecolare:926.09 g/mol1-(6-Amino-3,5-difluoro-2-pyridinyl)-7-[3-[3-[[1-(6-amino-3,5-difluoro-2-pyridinyl)-3-carboxy-8-chloro-6-fluoro-1,4-dihydro-4-oxo-7- quinolinyl]amino]-2-hydroxypropoxy]-1-azetidinyl]-8-chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid
CAS:<p>1-(6-Amino-3,5-difluoro-2-pyridinyl)-7-[3-[3-[[1-(6-amino-3,5-difluoro-2-pyridinyl)-3-carboxy-8-chloro-6-fluoro-1,4-dihydro-4-oxo-7-quinolinyl]amino]-2-hydroxypropoxy]-1-azetidinyl]-8-chloro-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid is a fluoroquinolone antibiotic, engineered through synthetic chemistry. It is derived from chemical sources involving complex organic synthesis, highlighting its intricate molecular architecture. Its mode of action is distinctive, as it inhibits bacterial DNA gyrase and topoisomerase IV, enzymes crucial for DNA replication and transcription. This interference with bacterial DNA processes results in bactericidal effects, effectively eliminating susceptible bacterial strains.</p>Formula:C36H24Cl2F6N8O8Purezza:Min. 95%Peso molecolare:881.52 g/molRef: 3D-AA184076
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