Antimicotici
Gli antifungini sono composti specificamente progettati per fermare, prevenire ed eliminare la crescita dei funghi. In questa categoria, troverete una vasta gamma di agenti antifungini essenziali per la ricerca e le applicazioni terapeutiche. Questi composti sono cruciali nel trattamento delle infezioni fungine e nella prevenzione delle loro recidive, rendendoli strumenti vitali sia in ambito medico che agricolo. Ricercatori e professionisti della salute possono esplorare numerosi antifungini per comprendere i loro meccanismi, ottimizzarne l'efficacia e sviluppare nuovi trattamenti per combattere ceppi fungini resistenti. L'ampia selezione di antifungini supporta i continui progressi nella ricerca sui funghi e lo sviluppo di terapie antifungine efficaci.
Trovati 835 prodotti di "Antimicotici"
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(R)-(-)-2-Oxothiazolidine-4-carboxylic Acid
CAS:Prodotto controllatoFormula:C4H5NO3SColore e forma:NeatPeso molecolare:147.15Gibberellin A7 Methyl Ester
CAS:Prodotto controllatoFormula:C20H24O5Colore e forma:NeatPeso molecolare:344.42-(1-(Allyloxy)-2-(1H-imidazol-1-yl)ethyl)-3,5-dichlorophenol
Prodotto controllatoFormula:C14H14Cl2N2O2Colore e forma:NeatPeso molecolare:313.1795-Fluoro-2-mercaptobenzothiazole
CAS:Prodotto controllato<p>Applications 5-Fluoro-2-mercaptobenzothiazole is used as a reagent in the synthesis of [[(benzothiazolyl)thio]methyl]phenyl]furanone derivatives with agrochemical fungicidal activities.<br>References Zhao, P., et al.: Youji Huaxue, 30, 1567 (2010);<br></p>Formula:C7H4FNS2Colore e forma:NeatPeso molecolare:185.24TH-302
CAS:Prodotto controllato<p>Applications TH-302 is a 2-nitroimidazole triggered hypoxia-activated prodrug (HAP) of bromo-isophosphoramide mustard. Studies have shown that TH-302 treatment exhibited hypoxia-selective cytotoxicity and DNA damage in human cancer cell<br>References Meng, F. et al.: Mol. Cancer Ther., 11, 740 (2012); Liu, Q. et al.: Cancer Chemother. Pharmacol., 69, 1487 (2012); Sun, J.D. et al.: Clin. Cancer Res., 18, 758 (2012);<br></p>Formula:C9H16Br2N5O4PColore e forma:NeatPeso molecolare:449.04α-Butylpiperonyl Alcohol
CAS:Prodotto controllato<p>Applications Intermediate in the preparation of insecticides, fungicides, and other pesticides.<br>References Wilkinson, C., et al.: J. Agric. Food Chem., 14, 73 (1966), Zhong, W., et al.: J. Chem. Res., 6, 370 (2009),<br></p>Formula:C12H16O3Colore e forma:NeatPeso molecolare:208.25cis-2-(2,4-Dichlorophenyl)-2-(4H-1,2,4-triazol-4-ylmethyl)-1,3-dioxolane-4-methanol
CAS:Prodotto controllato<p>Applications cis-2-(2,4-Dichlorophenyl)-2-(4H-1,2,4-triazol-4-ylmethyl)-1,3-dioxolane-4-methanol is an impurity in the synthesis of Itraconazole (I937500); an orally active antimycotic structurally related to Ketoconazol.<br>References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984); Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989); Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993)<br></p>Formula:C13H13Cl2N3O3Colore e forma:NeatPeso molecolare:330.171-(4-Chlorophenyl)-3-[(2-nitrophenyl)methoxy]pyrazole
CAS:Prodotto controllato<p>Applications 1-(4-Chlorophenyl)-3-[(2-nitrophenyl)methoxy]pyrazole is an intermediate for the synthesis of Pyraclostrobin-d6 (P840402). Isotope labelled Pyraclostrobin is a fungicide for use in seed grass and food crops.<br>References Gyldenkaerne, S., et al.: Pestic Sci., 55, 1210 (1999), Pennington, D., et al.: Environ. Sci. Technol., 39, 1119 (2005), Wang, S., et al.: Food Control., 18, 731 (2007),<br></p>Formula:C16H12ClN3O3Colore e forma:NeatPeso molecolare:329.74Nitrefazole
CAS:Prodotto controllato<p>Applications Nitrefazole is a nitroimidazole derivative with the ability to inhibit aldehyde dehydrogenase, and enzyme crucial to the metabolism of alcohol. This compound is suitable for aldehyde dehydrogenase (ALDH) related research.<br>References Klink, R. et al.: Arzneimittelforschung., 35, 1220 (1985); Koda L. et al.: Life Sci., 35, 1659 (1984);<br></p>Formula:C10H8N4O4Colore e forma:Light Yellow To YellowPeso molecolare:248.195-Mercapto-1H-1,2,3-triazole Sodium Salt
CAS:Prodotto controllato<p>Applications 5-Mercapto-1H-1,2,3-triazole Sodium Salt is used as a reactant in the preparation of cephem derivatives as anti-Helicobacter pylori agents in relation to lability towards β-lactamase and potential for causing diarrhea.<br>References Yoshida, Y., et al.: Bioorg. Med. Chem., 8, 2317 (2000);<br></p>Formula:C2H2N3NaSColore e forma:NeatPeso molecolare:123.111-Methyl-4-nitroimidazole
CAS:Prodotto controllato<p>Applications 1-Methyl-4-nitroimidazole is a moiety of Azathioprine (A803350) and is predicted to have mutagenic potential.<br>References Rosenkranz, H. S., et al.: Mutat. Res-Fund. Mol. M., 251, 157 (1991); Kelly, G. E., et al.: Photochem. Photobiol., 49, 59 (1989)<br></p>Formula:C4H5N3O2Colore e forma:White To Light YellowPeso molecolare:127.12-Methylbenzothiazole-6-carboxylic Acid (~90%)
CAS:Prodotto controllato<p>Applications 2-Methylbenzothiazole-6-carboxylic Acid (~90%) is a useful research chemical, a reagent for the synthetic studies on fungicidal agents.<br>References Saikachi, H., et al.: Yakugaku Zasshi, 78, 376 (1958); Bosco, M., et al.: Annali di Chimica, 58, 1148 (1968)<br></p>Formula:C9H7NO2SPurezza:~90%Colore e forma:NeatPeso molecolare:193.22(AlphaE)-2-[(6-Chloro-4-pyrimidinyl)oxy]-α-(methoxymethylene)benzeneacetic Acid Methyl Ester
CAS:Prodotto controllato<p>Applications (αE)-2-[(6-chloro-4-pyrimidinyl)oxy]-α-(methoxymethylene)benzeneacetic Acid Methyl Ester is an intermediate in the synthesis of Azoxystrobin (A965150), an strobilurin fungicide.<br></p>Formula:C15H13ClN2O4Colore e forma:NeatPeso molecolare:320.73[1,1'-Biphenyl]-4-yl(phenyl)(1-trityl-1H-imidazol-5-yl)methanol
Prodotto controllato<p>Applications [1,1'-Biphenyl]-4-yl(phenyl)(1-trityl-1H-imidazol-5-yl)methanol is an intermediate in synthesizing 2-Biphenylyl Sulfate-d5 Potassium Salt (B397897), which is the isotope labelled analog of 2-Biphenylyl Sulfate Potassium Salt. 2-Biphenylyl Sulfate Potassium Salt is a derivative of 2-Phenylphenol (P335870). 2-Phenylphenol is a agriculture fungicide and is no longer used as a food additive.<br>References Scheuhly, W., et al.: Chem. Biol., 18, 1053 (2011); Singh, H.P., et al.: Food. Chem. Toxicol., 48, 1040 (2010); Gouin, T., et al.: Envro. Pollu., 165, 208 (2012);<br></p>Formula:C41H32N2OColore e forma:NeatPeso molecolare:568.706Levofloxacin
CAS:<p>Levofloxacin is a fluoroquinolone antibiotic with a mode of action that inhibits bacterial DNA gyrase and topoisomerase IV. It is used for treating bacterial infections like pneumonia and urinary tract infections.</p>Formula:C18H20FN3O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:361.37 g/molBeauvericin
CAS:<p>Beauvericin is a cyclic peptide that is isolated from the fungus Fusarium. It has been shown to have antimicrobial activity against bacteria, as well as a variety of other biological properties. Beauvericin has been shown to inhibit mitochondrial membrane potential and induce toxicity in some animal models. Beauvericin also inhibits protein synthesis and causes cell death by inhibiting DNA polymerase activity. This compound is active against cancer cells, including HL-60 cells, which are derived from human lymphocytes and are used as a model for leukemia. Beauvericin can be extracted from an ETOA extract of the fungus Fusarium oxysporum; this extract has shown anti-cancer effects in vitro assays.</p>Formula:C45H57N3O9Purezza:Min. 95%Peso molecolare:783.95 g/mol2-Methyl-4-isothiazolin-3-one
CAS:Prodotto controllato<p>2-Methyl-4-isothiazolin-3-one or MIT is a powerful antimicrobial and antifungal agent which is widely used in personal care products. It is also used in industrial applications as a preservative and antifouling agent.</p>Formula:C4H5NOSPurezza:Min. 96%Colore e forma:Yellow PowderPeso molecolare:115.15 g/molAureothin
CAS:<p>Aureothin is a bioactive compound, classified as a polyketide antibiotic, which is derived from the culture of the bacterium Streptomyces thioluteus. This compound operates primarily through the inhibition of protein synthesis by interfering with the aminoacylation of tRNA with specific amino acids. Its mode of action disrupts cellular protein synthesis, which is essential for cell growth and function, leading to its potent antibacterial and antifungal activities.</p>Formula:C22H23NO6Purezza:Min. 95%Colore e forma:PowderPeso molecolare:397.42 g/molCaerulomycin A
CAS:<p>Caerulomycin A is a bioactive compound classified as a natural broad-spectrum antibiotic, which is derived from various Streptomyces species found in soil. Its mode of action involves inhibiting fungal and bacterial growth by interfering with essential cellular processes, effectively curbing the proliferation of pathogenic microorganisms. This potent molecule achieves its effects by binding to specific cellular targets, thereby disrupting cell wall synthesis and other critical metabolic pathways.</p>Formula:C12H11N3O2Purezza:Min. 95%Peso molecolare:229.23 g/molSordarin sodium salt
CAS:<p>Sordarin sodium salt is an antifungal agent, characterized as a semisynthetic derivative produced from the fermentation products of filamentous fungi, specifically belonging to the phylum Ascomycota. This compound exerts its effects by selectively inhibiting fungal protein synthesis. It achieves this by obstructing the function of elongation factor 2 (EF-2), an essential component of fungal ribosomal activity, thereby disrupting the translational elongation step of protein synthesis.</p>Formula:C27H39NaO8Purezza:Min. 95%Peso molecolare:514.58 g/molFilipin III
CAS:<p>Filipin III is a polyene macrolide antibiotic, which is extracted from Streptomyces filipinensis. Known for its unique mode of action, Filipin III interferes with cholesterol-rich membranes by binding to ergosterol and cholesterol. This interaction disrupts the membrane structure, altering membrane permeability and ultimately affecting cell viability.</p>Purezza:Min. 95%Naftifine N-Oxide
CAS:<p>Naftifine N-Oxide is an antifungal agent, which is derived from synthetic chemical processes. Its structure is based on the modification of the known antifungal, naftifine, by introducing an N-oxide functional group, which may enhance certain pharmacokinetic properties. As a synthetic derivative, Naftifine N-Oxide is specifically designed to interfere with the biosynthesis of ergosterol, an essential component of fungal cell membranes. By inhibiting squalene epoxidase, an enzyme crucial to the ergosterol pathway, Naftifine N-Oxide effectively disrupts the development and maintenance of the fungal cell membrane, compromising cell integrity and leading to antifungal activity.</p>Formula:C21H21NOPurezza:Min. 95%Peso molecolare:303.4 g/molNeoaureothin
CAS:<p>Neoaureothin is a natural antibiotic product, which is derived from marine actinomycetes with a complex polyketide structure. Its mode of action involves the inhibition of bacterial protein synthesis by binding selectively to the ribosomal subunits, thereby obstructing the translation process in susceptible microbial strains. The specificity of its action allows it to target a broad spectrum of Gram-positive bacteria while presenting a lower risk of resistance development compared to traditional antibiotics.</p>Formula:C28H31NO6Purezza:Min. 95%Peso molecolare:477.5 g/mol21-Norrapamycin
CAS:<p>21-Norrapamycin is a macrocyclic lactone antibiotic, which is derived from the bacterium Streptomyces hygroscopicus. Its chemical structure is closely related to that of rapamycin, a well-known immunosuppressant. The mode of action of 21-Norrapamycin involves the inhibition of the mechanistic target of rapamycin (mTOR) signaling pathway. By binding to the FK506-binding protein 12 (FKBP12), it forms a complex that then inhibits mTOR, a crucial regulator of cell growth, proliferation, and survival.</p>Formula:C50H77NO13Purezza:Min. 95%Peso molecolare:900.1 g/molZelkovamycin
CAS:<p>Zelkovamycin is a novel antibacterial compound isolated from endophytic microorganisms, specifically Streptomyces sp. Endophytes are bacteria or fungi that reside within plant tissues, forming symbiotic relationships and often producing bioactive metabolites. The mode of action of Zelkovamycin involves the inhibition of bacterial cell wall synthesis, interfering with the biosynthesis pathways essential for maintaining the structural integrity and function of bacterial cell walls, particularly in Gram-positive strains.</p>Formula:C36H45N9O9SPurezza:Min. 95%Colore e forma:PowderPeso molecolare:779.86 g/molPropiconazole
CAS:<p>Propiconazole is a triazole fungicide with action on fungal cell membranes by inhibiting ergosterol biosynthesis and is used for controlling fungal diseases in crops and turf.</p>Formula:C15H17Cl2N3O2Purezza:Min. 95%Colore e forma:Clear LiquidPeso molecolare:342.22 g/molMalformin C
CAS:<p>Malformin C is a cyclic pentapeptide, which is a secondary metabolite derived from certain strains of the fungus Aspergillus. Its mode of action involves disrupting cellular processes by interfering with cell division. Specifically, it is thought to affect mitotic spindle formation, leading to abnormal cell cycle progression.</p>Formula:C23H39N5O5S2Purezza:Min. 95%Colore e forma:PowderPeso molecolare:529.72 g/molMiconazole
CAS:<p>Anti-fungal; sterol 14α-demethylase inhibitor</p>Formula:C18H14Cl4N2OPurezza:Min. 95 Area-%Colore e forma:White Off-White PowderPeso molecolare:416.13 g/mol41-Oxo-rapamycin
CAS:<p>41-Oxo-rapamycin is a synthetic derivative of rapamycin, which is a macrocyclic lactone. It is derived from Streptomyces hygroscopicus, a gram-positive bacterium known for producing various bioactive compounds. The mode of action of 41-Oxo-rapamycin involves binding to the FK506-binding protein (FKBP12), forming a complex that subsequently inhibits the mammalian target of rapamycin (mTOR) pathway. This inhibition results in the suppression of T-cell proliferation and modulation of immune responses.</p>Formula:C51H77NO13Purezza:Min. 95%Peso molecolare:912.2 g/molHexamide
CAS:<p>Hexamide is a protein inhibitor.</p>Formula:C13H17NOColore e forma:SolidPeso molecolare:203.28SSF-109
CAS:<p>SSF-109 is a broad-spectrum fungicide, has protective activity against plant disease.</p>Formula:C15H18ClN3OPurezza:98%Colore e forma:SolidPeso molecolare:291.78Kayahope
CAS:<p>Kayahope is a novel antifungals.</p>Formula:C15H14ClNO3SPurezza:98%Colore e forma:SolidPeso molecolare:323.79Fenhexamid
CAS:<p>Fenhexamid (Elevate), a sterol biosynthesis inhibitor, shows antifungal activity against the plant pathogenic fungus.</p>Formula:C14H17Cl2NO2Purezza:99.56%Colore e forma:SolidPeso molecolare:302.20Fosravuconazole
CAS:<p>Fosravuconazole is a ravuconazole prodrug. It has antifungal activity.</p>Formula:C23H20F2N5O5PSPurezza:98%Colore e forma:SolidPeso molecolare:547.47Prochloraz
CAS:<p>Prochloraz: broad-spectrum imidazole fungicide; blocks placental aromatase (IC50=40nM), estrogen/androgen receptors; activates aryl hydrocarbon receptors.</p>Formula:C15H16Cl3N3O2Purezza:99.75% - 99.79%Colore e forma:Colorless SolidPeso molecolare:376.67Antifungal agent 67
CAS:<p>Compound 9 (Antifungal agent 67), an imidazole class antifungal, exhibits efficacy against Candida and possesses a CC50 value of 33.6 μM in neonatal rat</p>Formula:C23H25ClN2O3Colore e forma:SolidPeso molecolare:412.91Fuberidazole
CAS:<p>Fuberidazole is an antifungal agent.</p>Formula:C11H8N2OPurezza:98.95%Peso molecolare:184.19Silthiofam
CAS:<p>Silthiofam effectively combats Ggt, a wheat take-all fungus, now widely used for control in China.</p>Formula:C13H21NOSSiPurezza:98%Colore e forma:SolidPeso molecolare:267.46Fungicide4
CAS:<p>Fungicide4 exhibits the high activity against the P. infestans strain.</p>Formula:C14H11N3OColore e forma:SolidPeso molecolare:237.26Chitin synthase inhibitor 10
CAS:<p>Chitin Synthase Inhibitor 10: potent antifungal with 0.11 mM IC50, effective against resistant C. albicans and C. neoformans. Used in IFI research.</p>Formula:C24H23Br2N3O6Colore e forma:SolidPeso molecolare:609.26Isobellidifolin
CAS:<p>Isobellidifolin, a xanthone compound, serves as a free radical scavenger and antioxidant. It exhibits a potent antifungal effect.</p>Formula:C14H10O6Colore e forma:SolidPeso molecolare:274.23Cercosporamide
CAS:<p>Cercosporamide is a ATP-competitive Pkc1 kinase inhibitor (IC50 <50 nM; Ki <7 nM). It also is a unique Mnk inhibitor.</p>Formula:C16H13NO7Purezza:98%Colore e forma:SolidPeso molecolare:331.289-OxoOTrE
CAS:<p>9-OxoOTrE, made by oxidizing 9-HpOTrE, has antimicrobial effects on plant pathogens like bacteria and fungi.</p>Formula:C18H28O3Colore e forma:SolidPeso molecolare:292.41BHBM
CAS:<p>BHBM, an acylhydrazone antifungal, halts C. neoformans growth (MIC80 = 1 μg/ml) by blocking glucosylceramide synthesis.</p>Formula:C15H13BrN2O2Colore e forma:SolidPeso molecolare:333.18Ametoctradin
CAS:<p>Ametoctradin is a Qo-site inhibitor of mitochondrial respiratory complex III and is used in the study of oomycete diseases.</p>Formula:C15H25N5Purezza:99.65%Colore e forma:SolidPeso molecolare:275.39NB-598 hydrochloride
CAS:<p>NB-598 hydrochloride is a competitive squalene epoxidase (SE) inhibitor.</p>Formula:C27H32ClNOS2Purezza:98%Colore e forma:SolidPeso molecolare:486.13Antifungal agent 33
CAS:<p>Antifungal 33 (4e) strongly inhibits Candida albicans. MIC: 16 μg/ml; IC50: 0.19 μg/ml.</p>Formula:C21H14ClN5O3Colore e forma:SolidPeso molecolare:419.82Antifungal agent 22
CAS:<p>Orally active antifungal D16 (IC50: 0.5 μg/mL) passes blood-brain barrier, stable, low toxicity, targets C. neoformansH99 cells.</p>Formula:C21H26Cl3NOSColore e forma:SolidPeso molecolare:446.86P163-0892
CAS:<p>P163-0892: potent, specific antifungal for Cryptococcus; moderate blood-brain barrier penetration.</p>Formula:C19H20N2O3SColore e forma:SolidPeso molecolare:356.44
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