Antimicotici
Gli antifungini sono composti specificamente progettati per fermare, prevenire ed eliminare la crescita dei funghi. In questa categoria, troverete una vasta gamma di agenti antifungini essenziali per la ricerca e le applicazioni terapeutiche. Questi composti sono cruciali nel trattamento delle infezioni fungine e nella prevenzione delle loro recidive, rendendoli strumenti vitali sia in ambito medico che agricolo. Ricercatori e professionisti della salute possono esplorare numerosi antifungini per comprendere i loro meccanismi, ottimizzarne l'efficacia e sviluppare nuovi trattamenti per combattere ceppi fungini resistenti. L'ampia selezione di antifungini supporta i continui progressi nella ricerca sui funghi e lo sviluppo di terapie antifungine efficaci.
Trovati 910 prodotti di "Antimicotici"
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Miconazole
CAS:Anti-fungal; sterol 14α-demethylase inhibitorFormula:C18H14Cl4N2OPurezza:Min. 95 Area-%Colore e forma:White Off-White PowderPeso molecolare:416.13 g/molPropiconazole
CAS:Propiconazole is a triazole fungicide with action on fungal cell membranes by inhibiting ergosterol biosynthesis and is used for controlling fungal diseases in crops and turf.
Formula:C15H17Cl2N3O2Purezza:Min. 95%Colore e forma:Clear LiquidPeso molecolare:342.22 g/molBeauvericin
CAS:Beauvericin is a cyclic peptide that is isolated from the fungus Fusarium. It has been shown to have antimicrobial activity against bacteria, as well as a variety of other biological properties. Beauvericin has been shown to inhibit mitochondrial membrane potential and induce toxicity in some animal models. Beauvericin also inhibits protein synthesis and causes cell death by inhibiting DNA polymerase activity. This compound is active against cancer cells, including HL-60 cells, which are derived from human lymphocytes and are used as a model for leukemia. Beauvericin can be extracted from an ETOA extract of the fungus Fusarium oxysporum; this extract has shown anti-cancer effects in vitro assays.
Formula:C45H57N3O9Purezza:Min. 95%Peso molecolare:783.95 g/molLevofloxacin
CAS:Levofloxacin is a fluoroquinolone antibiotic with a mode of action that inhibits bacterial DNA gyrase and topoisomerase IV. It is used for treating bacterial infections like pneumonia and urinary tract infections.Formula:C18H20FN3O4Purezza:Min. 95%Colore e forma:PowderPeso molecolare:361.37 g/mol41-Oxo-rapamycin
CAS:41-Oxo-rapamycin is a synthetic derivative of rapamycin, which is a macrocyclic lactone. It is derived from Streptomyces hygroscopicus, a gram-positive bacterium known for producing various bioactive compounds. The mode of action of 41-Oxo-rapamycin involves binding to the FK506-binding protein (FKBP12), forming a complex that subsequently inhibits the mammalian target of rapamycin (mTOR) pathway. This inhibition results in the suppression of T-cell proliferation and modulation of immune responses.Formula:C51H77NO13Purezza:Min. 95%Peso molecolare:912.2 g/mol2-Methyl-4-isothiazolin-3-one
CAS:Prodotto controllato2-Methyl-4-isothiazolin-3-one or MIT is a powerful antimicrobial and antifungal agent which is widely used in personal care products. It is also used in industrial applications as a preservative and antifouling agent.Formula:C4H5NOSPurezza:Min. 96%Colore e forma:Yellow PowderPeso molecolare:115.15 g/molSordarin sodium salt
CAS:Sordarin sodium salt is an antifungal agent, characterized as a semisynthetic derivative produced from the fermentation products of filamentous fungi, specifically belonging to the phylum Ascomycota. This compound exerts its effects by selectively inhibiting fungal protein synthesis. It achieves this by obstructing the function of elongation factor 2 (EF-2), an essential component of fungal ribosomal activity, thereby disrupting the translational elongation step of protein synthesis.
Formula:C27H39NaO8Purezza:Min. 95%Peso molecolare:514.58 g/molNeoaureothin
CAS:Neoaureothin is a natural antibiotic product, which is derived from marine actinomycetes with a complex polyketide structure. Its mode of action involves the inhibition of bacterial protein synthesis by binding selectively to the ribosomal subunits, thereby obstructing the translation process in susceptible microbial strains. The specificity of its action allows it to target a broad spectrum of Gram-positive bacteria while presenting a lower risk of resistance development compared to traditional antibiotics.Formula:C28H31NO6Purezza:Min. 95%Peso molecolare:477.5 g/molNaftifine N-Oxide
CAS:Naftifine N-Oxide is an antifungal agent, which is derived from synthetic chemical processes. Its structure is based on the modification of the known antifungal, naftifine, by introducing an N-oxide functional group, which may enhance certain pharmacokinetic properties. As a synthetic derivative, Naftifine N-Oxide is specifically designed to interfere with the biosynthesis of ergosterol, an essential component of fungal cell membranes. By inhibiting squalene epoxidase, an enzyme crucial to the ergosterol pathway, Naftifine N-Oxide effectively disrupts the development and maintenance of the fungal cell membrane, compromising cell integrity and leading to antifungal activity.Formula:C21H21NOPurezza:Min. 95%Peso molecolare:303.4 g/molAureothin
CAS:Aureothin is a bioactive compound, classified as a polyketide antibiotic, which is derived from the culture of the bacterium Streptomyces thioluteus. This compound operates primarily through the inhibition of protein synthesis by interfering with the aminoacylation of tRNA with specific amino acids. Its mode of action disrupts cellular protein synthesis, which is essential for cell growth and function, leading to its potent antibacterial and antifungal activities.Formula:C22H23NO6Purezza:Min. 95%Colore e forma:PowderPeso molecolare:397.42 g/molChitin synthase inhibitor 13
CAS:Chitin Synthase Inhibitor 13 (compound 12g), a non-competitive antagonist of chitin synthase, demonstrates broad-spectrum antifungal activity and has anFormula:C21H19N5O5SColore e forma:SolidPeso molecolare:453.47Benthiavalicarb isopropyl
CAS:Benthiavalicarb isopropyl is a fungicide, specifically targeting downy mildew and blight.Formula:C18H24FN3O3SPurezza:98%Colore e forma:SolidPeso molecolare:381.46Aliconazole
CAS:Aliconazole is an imidazole derivative with antifungal activity for the study of skin infections.Formula:C18H13Cl3N2Purezza:99.21% - 99.79%Colore e forma:SolidPeso molecolare:363.67SCY-078 phosphate
CAS:SCY-078 phosphate is a novel glucan synthesis inhibitor.Formula:C44H70N5O8PColore e forma:SolidPeso molecolare:828.04Fosravuconazole
CAS:Fosravuconazole is a ravuconazole prodrug. It has antifungal activity.Formula:C23H20F2N5O5PSPurezza:98%Colore e forma:SolidPeso molecolare:547.47SCH51048
CAS:SCH 51048 is a broad spectrum antifungal with oral activity.Formula:C37H42F2N8O3Colore e forma:SolidPeso molecolare:684.78D13
CAS:D13 acylhydrazone antifungal; MIC80: 0.06 μg/ml vs. C. neoformans; boosts mouse survival against fungal infections at 20 mg/kg/day orally.Formula:C14H9Br3N2O2Colore e forma:SolidPeso molecolare:476.95Succinate dehydrogenase-IN-1
CAS:Succinate dehydrogenase-IN-1 (Compound 34) acts as an inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 value of 0.94 μM and a KD of 22.4 μM. This compound also demonstrates antifungal activity, with EC50 values against Rhizoctonia solani, Sclerotinia sclerotiorum, Monilinia fructicola, and Botrytis cinerea measured at 0.04 μM, 1.13 μM, 1.61 μM, and 1.21 μM, respectively.Formula:C20H13F6N3OColore e forma:SolidPeso molecolare:425.33Tebuconazole-d9
CAS:Tebuconazole-d9 is a GC/LC-MS standard for quantifying the triazole fungicide tebuconazole, affecting seed/foliar fungi and androgen receptors.Formula:C16H13ClD9N3OColore e forma:SolidPeso molecolare:316.87Asulam-potassium
CAS:Asulam-potassium is a dihydropteroate synthase inhibitor used as an herbicide (mainly for killing bracken). It contains an asulam(1-).Formula:C8H9KN2O4SColore e forma:SolidPeso molecolare:268.33Antifungal agent 73
CAS:Antifungal agent 73 (compound A32) effectively combats azole-resistant candidiasis by disrupting the fungal cell wall and membrane.Formula:C21H16Cl2N2O3Colore e forma:SolidPeso molecolare:415.27Buclosamide
CAS:Buclosamide is a topical antimycotic agent that can be used in dermatomycoses [1].Formula:C11H14ClNO2Colore e forma:SolidPeso molecolare:227.69Antifungal agent 69
CAS:Antifungal agent 69 (compound 13), a eugenol-imidazole derivative, demonstrates targeted activity against Candida albicans with a minimum inhibitoryFormula:C23H23ClN2O4Colore e forma:SolidPeso molecolare:426.89Haloprogin
CAS:Haloprogin is an antifungal agent with inhibitory activity against dermatophytes, Candida, and some Gram-positive bacteria.Formula:C9H4Cl3IOPurezza:98.18%Colore e forma:SolidPeso molecolare:361.39Stemphyperylenol
CAS:Stemphyperylenol: antifungal, targets Alternaria solani, MIC at 1.57 μM.Formula:C20H16O6Colore e forma:SolidPeso molecolare:352.34Flutolanil
CAS:Flutolanil: a fungicide targeting R. solani in rice, toxic to zebrafish.Formula:C17H16F3NO2Colore e forma:SolidPeso molecolare:323.31(Z)-Fluoxastrobin
CAS:(Z)-Fluoxastrobin is a fungicide that exhibits effective control of important seed and soil-borne pathogens.Formula:C21H16ClFN4O5Colore e forma:SolidPeso molecolare:458.83Antifungal agent 31
CAS:Orally active triazole, antifungal 31 with pyrrolizinone structure, combats Candida, reduces mortality and renal infection in mice.Formula:C25H22F2N6O3Colore e forma:SolidPeso molecolare:492.48Exalamide
CAS:Exalamide (2-(Hexyloxy)benzamide) is an aromatic amide with antifungal activity used in the study of dermatophytes.Formula:C13H19NO2Purezza:99.61%Colore e forma:White PowderPeso molecolare:221.3Etisazole
CAS:Etisazole is an animal antifungal agent with skin sensitizing properties to humans.Formula:C9H10N2SColore e forma:SolidPeso molecolare:178.25Chitin synthase inhibitor 3
CAS:Compound 2d is a potent chitin synthase inhibitor (IC50: 0.16 mM, MIC: 1 μg/mL vs. Candida albicans) with antifungal properties.Formula:C20H19N3O4Colore e forma:SolidPeso molecolare:365.38Chlordantoin
CAS:Chlordantoin is an antifungal agent with the potential for vaginal candidiasis treatment.Formula:C11H17Cl3N2O2SPurezza:98%Colore e forma:SolidPeso molecolare:347.69Antifungal agent 59
CAS:Antifungal agent 59 exhibits potent activity, reflected by MIC values ranging from 0.01 to 1 μg/mL, and inhibits the formation of fungal biofilms, whileFormula:C18H15BrF2N2SeColore e forma:SolidPeso molecolare:456.19Zarilamide
CAS:Zarilamide disrupts microtubules, inhibiting mitosis in Phytophthora capsici zoospore cysts.Formula:C11H11ClN2O2Colore e forma:SolidPeso molecolare:238.67Chaetochromin
CAS:Chaetochromin (4548-G05, NSC 345647) is an oral, selective insulin receptor agonist with potent, lasting antidiabetic effects in mice.Formula:C30H26O10Colore e forma:SolidPeso molecolare:546.52Globosuxanthone A
CAS:Globosuxanthone A: a dihydroxanthenone with anticancer and antifungal properties (MIC: F. graminearum 4, F. solani 8, B. cinerea 16 μg/mL).Formula:C15H12O7Colore e forma:SolidPeso molecolare:304.25Hexamide
CAS:Hexamide is a protein inhibitor.Formula:C13H17NOColore e forma:SolidPeso molecolare:203.28RO-09-4609
CAS:RO-09-4609 is a potent and selective inhibitor of Candida albicans N-myristoyltransferase (CaNmt).Formula:C21H24N2O4Colore e forma:SolidPeso molecolare:368.43Silthiofam
CAS:Silthiofam effectively combats Ggt, a wheat take-all fungus, now widely used for control in China.Formula:C13H21NOSSiPurezza:98%Colore e forma:SolidPeso molecolare:267.46Posaconazole hydrate
CAS:Posaconazole: broad-spectrum antifungal, second-gen triazole, strong C14α demethylase inhibitor (IC50: 0.25 nM).Formula:C37H44F2N8O5Purezza:98%Colore e forma:SolidPeso molecolare:718.79Antifungal agent 22
CAS:Orally active antifungal D16 (IC50: 0.5 μg/mL) passes blood-brain barrier, stable, low toxicity, targets C. neoformansH99 cells.Formula:C21H26Cl3NOSColore e forma:SolidPeso molecolare:446.86P163-0892
CAS:P163-0892: potent, specific antifungal for Cryptococcus; moderate blood-brain barrier penetration.Formula:C19H20N2O3SColore e forma:SolidPeso molecolare:356.44Metyltetraprole
CAS:Metyltetraprole: potent fungicide, effective against Zymoseptoria, low EC50 (0.002 ppm), inhibits respiratory chain.Formula:C19H17ClN6O2Colore e forma:SolidPeso molecolare:396.83Antifungal agent 32
CAS:Antifungal 32 (1a) strongly inhibits Candida albicans growth, filamentation, biofilm, and adhesion.Formula:C25H28N2OColore e forma:SolidPeso molecolare:372.5Tolindate
CAS:Tolindate, a potent PXR agonist, demonstrates antifungal activity and possesses an EC50 value of 8.3 µM.Formula:C18H19NOSColore e forma:SolidPeso molecolare:297.41NB-598 hydrochloride
CAS:NB-598 hydrochloride is a competitive squalene epoxidase (SE) inhibitor.Formula:C27H32ClNOS2Purezza:98%Colore e forma:SolidPeso molecolare:486.13Antifungal agent 68
CAS:Antifungal agent 68 (compound 10) effectively combats fungal infections caused by Candida and Cryptococcus gattii through the inhibition of ergosterolFormula:C23H27ClN2O3Colore e forma:SolidPeso molecolare:414.93Apogossypolone (ApoG2)
CAS:Apogossypolone (ApoG2) is a semi-synthesized derivative of gossypol which is a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins with K iFormula:C28H26O8Colore e forma:SolidPeso molecolare:490.5Isobellidifolin
CAS:Isobellidifolin, a xanthone compound, serves as a free radical scavenger and antioxidant. It exhibits a potent antifungal effect.Formula:C14H10O6Colore e forma:SolidPeso molecolare:274.23Fenhexamid
CAS:Fenhexamid (Elevate), a sterol biosynthesis inhibitor, shows antifungal activity against the plant pathogenic fungus.Formula:C14H17Cl2NO2Purezza:99.56%Colore e forma:SolidPeso molecolare:302.20
