Antimicotici

Dactylfungins A: antifungal from Dactylaria Parvispora, effective against fungi like Candida pseudotropicalis, MIC < 10 µg/ml.

Picarbutrazox: potent pesticide/fungicide for corn/soybean against Pythium/Phytophthora.

Enniatin F is a natural product that can be used as a reference standard. The CAS number of Enniatin F is 144446-20-8.

Compound 6c, a tetrazole derivative, inhibits ergosterol synthesis and disrupts C. albicans cell membranes with potent antifungal effects.

L-4-Oxalysine hydrochloride has shown antitumor activities, is a natural product isolated from the culture media of Streptomyces roseovirdofuscus in China.

Triphala: Ayurvedic mix, blocks NF-κB, antifungal, anti-inflammatory, fights fat & cancer.

<p>Stichloroside B1 is a triterpene saponin.</p>

Thujopsene, a sesquiterpene found in T. dolabrata, exhibits a wide range of biological activities. It inhibits Na+/K+-ATPase and cytochrome P450 (CYP) isoform CYP2B6 with IC50 values of 25.9 µg/ml and Ki of 0.8 µM, respectively. Additionally, thujopsene demonstrates antimicrobial efficacy against both Gram-positive and Gram-negative bacteria, such as S. aureus, M. luteus, and S. typhimurium, with MICs ranging from 25-50 µg/ml. It also suppresses antigen-induced β-hexosaminidase release in IgE-sensitized RBL-2H3 mast cells (IC50= 25.1 µM) and shows cytotoxicity against A549 non-small cell lung cancer cells with an LC50 of 35.27 µg/ml. Furthermore, thujopsene causes mortality in mites D. farinae and T. putrescentiae, with LC50s of 9.82 and 10.92 µg/cm2, respectively.

Compound 3a (Antifungal agent 62) exhibits potent fungicidal properties, particularly against Fusarium oxysporum f.sp.

Compound A07, effective against Fluconazole-resistant fungi, outperforms Miconazole, inhibits Candida at 0.25-1 μg/mL MIC.

Corydalmine hydrochloride: antifungal, oral analgesic, soothes neuropathic pain by blocking NF-κB/CXCL1/CXCR2.

CYP51/PD-L1-IN-2 (compound L20), a quinazoline with antifungal properties, is a potent dual inhibitor targeting both CYP51 (IC50: 0.263 μM) and PD-L1 (IC50: 0.

Latrunculin B: alkaloid, inhibits actin polymerization, antifungal, antiprotozoal, modulates heart rhythm, studied in glaucoma.

Ent-Heronamide C possesses antifungal properties and is utilized as a probe for analyzing the mode of action of heronamide C [1].

Compound B01, an antifungal, inhibits Candida albicans in vitro/vivo for invasive fungal infection research.

Antifungalagent 128 (Compound 3ja) is an antifungal agent that, in combination with Fluconazole, has a MIC range of 0.5-4 μg/mL against C. albicans strains. It is applicable in the study of anti-infective therapies.

Sclerotiorin, from Penicillium, inhibits soybean lipoxygenase-1 (IC50: 4.2 μM) and other proteins, antagonizes endothelin receptors.

Diclobutrazol: potent systemic fungicide against rusts, mildews, and crop diseases.

PK-10, when combined with Fluconazole, exhibits potent synergistic antifungal activity against multiple Fluconazole-resistant Candida albicans strains.