Antimicrobici

<p>Bisphenol A d14 is an isotopically labeled compound, which is a variant of Bisphenol A (BPA) where hydrogen atoms are partially replaced with deuterium isotopes. This compound is produced through chemical synthesis, ensuring that 14 of the hydrogen atoms in the BPA molecule are replaced by deuterium to create a stable form with a slightly higher atomic mass, facilitating advanced analytical studies.</p>

<p>Avermectin A1b is an antiparasitic compound, which is a macrocyclic lactone isolated from the soil bacterium *Streptomyces avermitilis*. This compound functions primarily by enhancing the release of gamma-aminobutyric acid (GABA) and binding to glutamate-gated chloride channels in nerve and muscle cells of parasites. This interaction leads to an increase in the permeability of cell membranes to chloride ions, resulting in paralysis and death of the parasite.</p>

<p>Inducer of apoptosis; translational inhibitor; aminonucleoside antibiotic</p>

<p>Griseoluteic acid is a cyclic lipopeptide that inhibits bacterial growth by binding to the enzyme cyclase, which is involved in the production of cyclic AMP. Griseoluteic acid also inhibits the synthesis of rRNA (ribosomal RNA), which is required for protein synthesis. The compound has been shown to have a high degree of resistance against antibiotic-resistant strains and exhibits a low toxicity profile in vitro. Griseoluteic acid also has an inhibitory effect on hydrogen bonding interactions, which may be due to its ability to inhibit energy metabolism. This compound also exhibits anti-inflammatory properties and has been shown to have neurodevelopmental effects in animal models.</p>

Triazoxide-desoxy is an investigational compound, which is a synthetic derivative of triazoxide, originating from pharmacological research aimed at modulating physiological pathways. This compound acts primarily by influencing ion channel activity at a cellular level, impacting the regulation of potassium channels which are crucial for maintaining cellular homeostasis and signaling.

4′-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethylavermectin A1a is a semi-synthetic derivative of avermectin, which is a naturally occurring compound isolated from the fermentation broth of the soil bacterium *Streptomyces avermitilis*. This compound exhibits potent antiparasitic activity by targeting the glutamate-gated chloride channels in the nervous systems of parasitic organisms. By binding and activating these channels, it increases the permeability of the cell membrane to chloride ions, resulting in paralysis and death of the parasite.

Imipenem acts as an antimicrobial through inhibiting cell wall synthesis of various gram-positive and gram-negative bacteria. It remains very stable in the presence of beta-lactamase (both penicillinase andcephalosporinase) produced by some bacteria, and is a strong inhibitor of beta-lactamases from some gram-negative bacteria that are resistant to most beta-lactam antibiotics.

Baringolin is a peptide-based antibiotic, which is derived from marine sources, specifically linked to natural products obtained from marine microorganisms. Its mode of action involves the inhibition of bacterial protein synthesis, which is achieved by interfering with the bacterial ribosome. This inhibition disrupts the ability of bacteria to produce essential proteins, ultimately leading to cell death.

<p>(-)-Anthrabenzoxocinone is a type of polyketide compound, which is a natural product derived from microbial sources, specifically Streptomyces species. This compound is characterized by its complex aromatic structure, which is a hallmark of polyketides known for their diverse biological activities. The mode of action of (-)-anthrabenzoxocinone primarily involves the inhibition of bacterial RNA synthesis, reflecting its role as an antibiotic. Additionally, it exhibits potential antitumor activity, possibly through the inhibition of topoisomerase enzymes that are crucial for DNA replication and transcription.</p>

<p>2,4,5,6-Tetrachlorophenol-13C6 is an isotopically labeled chemical compound, primarily used as a reference standard in analytical chemistry. This compound, derived from its non-labeled counterpart 2,4,5,6-tetrachlorophenol, is synthesized through the incorporation of carbon-13 isotopes. Its primary mode of action involves acting as a stable, traceable marker, facilitating accurate quantification and analysis of environmental samples, particularly in mass spectrometry.</p>

SARS-CoV Mpro-in-1 is a chemical compound that acts as a selective inhibitor of the main protease (Mpro) of the SARS coronavirus. This inhibitor is synthesized through chemical processes, leveraging medicinal chemistry techniques aimed at designing molecules that specifically target viral proteases. Its mode of action involves binding to the active site of the SARS-CoV main protease, thereby blocking the protease's enzymatic activity essential for viral replication. Inhibition occurs by preventing the cleavage of the viral polyprotein, an event crucial for producing the mature, functional proteins that the virus needs to proliferate within the host.

Posaconazole-d5 is a deuterated form of the antifungal agent posaconazole, which is a synthetic compound derived from triazole. The substitution of hydrogen atoms with deuterium in this compound allows for enhanced stability and differentiation in analytical applications, particularly in pharmacokinetic and metabolic studies.

<p>Radicinol is a natural compound, which is a dihydroflavonol primarily sourced from plant origins. This compound is biosynthesized in specific plant species and extracted through meticulous biochemical processes to ensure its purity and efficacy. The mode of action of Radicinol involves the modulation of specific cellular pathways, conferring antioxidative and anti-inflammatory properties. It acts by scavenging free radicals and enhancing cellular resilience against oxidative stress.</p>

<p>Didesethyl chloroquine hydroxyacetamide-d4 is a deuterated pharmaceutical compound, which serves as a stable isotope-labeled analog. Such compounds are often synthesized in specialized laboratories for research purposes, providing insightful data on pharmacokinetics and metabolic pathways. The deuteration, involving the replacement of hydrogen atoms with deuterium, offers enhanced accuracy in mass spectrometry analysis due to its unique isotopic signature.</p>

<p>Gentamicin C2 pentaacetate (2 : 1 Mixture of C2 and C2a) is an aminoglycoside class antibiotic derivative, primarily derived from the fermentation of Micromonospora species. This product is a semi-synthetic compound, combining two closely related gentamicin components, C2 and C2a, in a specified ratio. Its mode of action involves binding to the 30S subunit of the bacterial ribosome, which disrupts protein synthesis resulting in bactericidal activity against a wide spectrum of Gram-negative and some Gram-positive bacteria.</p>

Nojirimycin bisulfite is a potent glycosidase inhibitor, which is a derivative of nojirimycin known for its significant impact on carbohydrate metabolism. This compound originates from microorganisms, primarily isolated from the bacterium *Streptomyces* species. The mechanism through which Nojirimycin bisulfite exerts its effects involves the inhibition of glycosidases, enzymes responsible for breaking down complex carbohydrates into simpler sugars. By interfering with these enzymes, Nojirimycin bisulfite disrupts the normal processing of carbohydrates.

<p>Pyraoxystrobin is a fungicidal compound, which is a chemically synthesized strobilurin derivative. It functions by disrupting the mitochondrial respiration in fungi. Specifically, pyraoxystrobin inhibits the cytochrome bc1 complex in the electron transport chain, effectively preventing adenosine triphosphate (ATP) synthesis.</p>

<p>Fosmidomycin sodium is an antibiotic compound, which is derived from phosphonic acid. It functions as an inhibitor of the enzyme 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR), crucial in the non-mevalonate pathway of isoprenoid biosynthesis. By targeting this enzyme, fosmidomycin sodium disrupts the production of isoprenoids, essential components for the growth and survival of certain bacteria and parasites.</p>

<p>Desmethyl ferroquine is an antimalarial compound, which is a derivative of ferroquine. It is synthesized through chemical modification processes, specifically designed to enhance its pharmacokinetic and pharmacodynamic properties. This compound exhibits its mode of action by compromising the integrity of the Plasmodium parasite's digestive vacuole. By doing so, it disrupts heme detoxification, which is crucial for the parasite’s survival within red blood cells.</p>

<p>(2RS,4S)-2-[[(Phenylacetyl)amino]methyl]-5,5-dimethylthiazolidine-4-carboxylic acid, commonly referred to as penilloic acids, is a hydrolytic degradation product of benzylpenicillin. It is derived through the enzymatic or chemical cleavage of the β-lactam ring of benzylpenicillin, which is a classic β-lactam antibiotic.</p>

<p>Licoflavone B is a naturally occurring flavonoid, which is primarily derived from the roots of licorice plants, such as Glycyrrhiza inflata. It functions as a bioactive compound with potential antioxidant and anti-inflammatory activities. The mode of action of Licoflavone B involves the scavenging of free radicals, modulation of signaling pathways, and inhibition of pro-inflammatory mediators. These biological activities render it valuable in research focused on chronic diseases and oxidative stress.</p>

<p>Vapendavir diphosphate is an antiviral compound, which is a synthesized small molecule with selective activity targeting picornaviruses. This compound is derived from rigorous medicinal chemistry efforts focusing on the inhibition of viral replication. Vapendavir diphosphate functions by binding to a specific site on the viral capsid, thereby inhibiting the uncoating process essential for viral RNA release into the host cell. This mode of action effectively prevents the virus from replicating within the host.</p>

<p>Fluhexafon is an innovative acaricide, which is derived from advanced chemical synthesis. Its mode of action involves disrupting critical biological processes in mites, specifically targeting nerve receptor pathways to inhibit their survival and reproduction. By interfering with the neurotransmission, it effectively reduces mite populations, ensuring healthier crops.</p>

Phthalic acid, bis[2-(2-ethoxyethoxy)ethyl] ester is a specialized industrial plasticizer, which is a type of additive used to enhance the flexibility and durability of polymer-based materials. It is derived from phthalic acid through esterification with ethylene glycol ether derivatives, resulting in a compound that effectively reduces the brittleness of plastic formulations by increasing their plasticity.

Fradimycin B is an aminoglycoside antibiotic, which is derived from the bacterium Streptomyces. It exhibits its mode of action by binding to the bacterial 30S ribosomal subunit, thereby inhibiting protein synthesis. This results in a bactericidal effect, effectively disrupting the growth and proliferation of susceptible bacterial strains.

<p>6-Amino-1-cyclopropyl-7-(3,4-dihydro-1H-isoquinolin-2-yl)-8-methyl-4-oxoquinoline-3-carboxylic acid is a synthetic quinolone antibiotic, which is derived from chemical synthesis processes designed to mimic the naturally occurring quinolone core structure. With a specific mechanism of action, it inhibits bacterial DNA gyrase and topoisomerase IV. These enzymes are critical for supercoiling and uncoiling DNA, meaning that their inhibition results in an inability of bacterial cells to properly replicate their DNA, ultimately leading to cell death.</p>

Tobramycin sulfate is an aminoglycoside antibiotic, which is derived from selected strains of Streptomyces tenebrarius. It functions by binding irreversibly to the 30S subunit of bacterial ribosomes, thereby inhibiting protein synthesis. This disruption in essential protein formation results in bactericidal activity, particularly against Gram-negative bacteria.

<p>Vineomycin A1 is a cytotoxic antibiotic, which is isolated from the fermentation broth of certain Streptomyces species. This compound is a member of the anthracycline class of antibiotics, known for their potent antitumor activity. Vineomycin A1 exerts its effects by intercalating into DNA, disrupting the DNA replication process and ultimately inducing apoptosis in rapidly dividing cells. This mode of action makes it a valuable tool in studying cellular responses to DNA damage and has potential implications in cancer research. Leveraging its ability to target malignant cells, Vineomycin A1 is primarily examined for its therapeutic potential in oncology, particularly in treating certain types of cancers that are resistant to standard therapies. As a research chemical, it enables scientists to gain insights into the mechanisms of drug resistance and DNA repair pathways, contributing to the development of novel cancer treatment strategies.</p>

A2ti-1 is a specialized therapeutic agent, which is derived from recombinant DNA technology with the specific mode of action of targeting and modulating cytokine signaling pathways within the immune system. It is designed to interact with specific cytokine receptors, thereby inhibiting or modulating the downstream signaling cascades that are pivotal in the inflammatory response and immune regulation.

<p>SE 563 is a biocontrol agent, which is an organism-based product derived from natural sources. It is sourced from a specific strain of entomopathogenic nematodes known for their effectiveness in targeting and controlling insect pests. The mode of action involves the nematodes seeking out their insect hosts in the soil, entering through natural openings, and releasing symbiotic bacteria that kill the host from within.</p>

N-(4-Hexylphenyl)-5-nitro-2-furancarboxamide is a synthetic organic compound, categorized as a nitroaromatic amide. It is synthesized through a condensation reaction involving 4-hexylphenylamine and 5-nitro-2-furancarboxylic acid. The compound's mode of action involves the potential to interfere with specific biomolecular interactions due to its structure, which includes a nitro group capable of engaging in electron transfer reactions. These interactions may modulate enzymatic activities or alter binding affinities between proteins and other biomolecules.

Acetoxypolygodial is a sesquiterpenoid compound, which is a naturally derived product from the roots of the plant Polygonum hydropiper. This compound exhibits its mode of action through its ability to disrupt microbial cell membranes, leading to increased permeability and eventual cell death. Its primary mechanism involves direct interaction with lipid bilayers, causing destabilization.

Fosravuconazole is an antifungal agent, classified as a triazole antifungal, which is developed from a synthetic chemical source. It operates as a prodrug of ravuconazole, meaning that after administration, fosravuconazole is converted into its active form in the body. This conversion enhances the absorption and bioavailability of the drug, providing improved treatment efficacy against fungal infections.

<p>Artelinic acid is a synthetic antimalarial agent, which is derived from artemisinin, a natural compound sourced from the sweet wormwood plant (Artemisia annua). The mode of action of Artelinic acid involves the generation of free radicals within the Plasmodium parasite, leading to oxidative stress and damage to the parasite’s cellular components, ultimately resulting in parasite death. This mechanism is particularly effective against Plasmodium species, including those strains resistant to other antimalarial drugs.</p>

<p>(Z)-Fenpyroximate is a selective acaricide, which is a chemical agent specifically designed to control mite populations. It is derived from the chemical class of pyrazole compounds. The mode of action of (Z)-Fenpyroximate involves the inhibition of the mitochondrial electron transport chain, particularly targeting complex I (NADH: ubiquinone oxidoreductase). This disruption prevents ATP production, leading to mite mortality due to energy starvation.</p>

<p>Bacitracin A is an antibiotic peptide, which is isolated from the bacterium Bacillus subtilis. It functions by interfering with the cell wall synthesis of bacteria. Specifically, Bacitracin A inhibits the dephosphorylation of the C55-isoprenyl pyrophosphate molecule, an essential lipid carrier that transports peptidoglycan building blocks to the growing cell wall. This disruption leads to the inhibition of peptidoglycan synthesis, a critical component of bacterial cell walls, resulting in cell lysis and death.</p>

Metalaxyl-hydroxymethyl is a systemic fungicide, which is synthesized chemically. With its unique mechanism of action as an acylalanine fungicide, it targets and disrupts RNA synthesis specifically in oomycetes—a group of fungus-like organisms. This disruption inhibits the growth and spread of pathogenic fungi.

<p>MCB-3681 is a small-molecule inhibitor, which is synthesized through advanced chemical processes. It operates at a molecular level by selectively targeting and inhibiting specific cellular pathways involved in cancer cell proliferation. The compound's action is characterized by its ability to interfere with enzyme activity crucial for the survival and growth of malignant cells, thus inducing apoptosis and inhibiting tumor progression.</p>

<p>Atisinium chloride is an organometallic compound, which is synthesized through advanced coordination chemistry techniques. The source of this compound lies in the strategic combination of organic ligands with metal centers, facilitating unique interactions that are pivotal to its functionality. The mode of action primarily involves the ability to participate in complex catalytic cycles, engaging in electron transfer processes that are essential for mediating chemical transformations.<br><br>This compound finds applications in specialized fields such as catalysis, where it is utilized to promote and drive reactions that may be inefficient under normal conditions. Its effectiveness in altering reaction pathways and increasing selectivity makes it valuable in synthetic chemistry and industrial processes. Additionally, atisinium chloride's unique properties might be leveraged in materials science for the development of novel materials with tailored functionalities. The intricate balance of its reactive properties and stability under varying conditions makes it a subject of ongoing research for further applications.</p>

Ent-avibactam sodium is a pharmacological agent, categorized as a beta-lactamase inhibitor, which is synthetically derived. This compound acts by binding to and inhibiting the action of beta-lactamase enzymes produced by certain bacteria, thereby preventing the breakdown of beta-lactam antibiotics. Consequently, it restores the effectiveness of these antibiotics against resistant strains.

<p>Tri-O-benzyl FR 900098 is a chemical compound, often referenced in biochemical research contexts. It is a synthetic derivative that originates from complex chemical synthesis, involving multiple benzylation steps to modify the original molecular framework. This structural transformation lends the compound unique chemical properties.</p>

<p>Please enquire for more information about Cefetrizole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Pyrenophorin is a polyketide metabolite, which is derived from certain fungi, specifically from the genus Pyrenophora. This compound demonstrates its biological efficacy through its unique mode of action as an antimicrobial agent, interfering with cellular processes in target microorganisms, leading to their inhibition or death.</p>

<p>Telavancin is a lipoglycopeptide antibiotic, which is a semi-synthetic derivative of vancomycin. Its source is derived through modifications of the glycopeptide antibiotic, specifically aimed to enhance antibacterial activity. Telavancin functions by inhibiting cell wall synthesis in Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). It does this by binding to the D-alanyl-D-alanine terminus of cell wall precursors, disrupting peptidoglycan polymerization and, consequently, cell wall integrity. Additionally, Telavancin increases membrane permeability and disrupts membrane potential, further enhancing its bactericidal activity.</p>

<p>Viramidine hydrochloride is an antiviral prodrug with action as a precursor to ribavirin, targeting viral RNA synthesis and is used for research on hepatitis C and other viral infections.</p>

Sofosbuvir d6 is a deuterated antiviral drug used for the treatment of Hepatitis C virus (HCV) infection, which is synthesized chemically. This modification involves the replacement of hydrogen atoms with deuterium, a stable isotope of hydrogen, resulting in enhanced pharmacokinetic properties. By incorporating deuterium, the metabolic stability of the compound is improved due to the kinetic isotope effect, which slows down the metabolic degradation of the compound.

<p>Picarbutrazox is a fungicide, which is a product derived from chemical synthesis designed to protect crops by inhibiting fungal growth. It works through a specific mode of action that targets and disrupts the biosynthesis of essential lipids within fungal cells. This disruption ultimately leads to the cessation of cell membrane formation, impeding the growth and proliferation of the fungi.</p>

<p>MGB-BP-3 is a synthetic antimicrobial agent, which is derived from natural DNA-binding minor groove binder (MGB) compounds. Its structure is based on distamycin, known for targeting the minor groove of DNA. MGB-BP-3 operates by binding to specific sequences within the DNA minor groove, thereby interfering with the replication and transcription processes of bacterial cells. This binding disrupts the DNA function and inhibits the growth and proliferation of bacterial pathogens.</p>

Deoxylapachol is a naturally occurring metabolite, which is derived from the heartwood of certain Tabebuia tree species. It is a type of naphthoquinone, recognized for its biologically active properties. The mode of action of deoxylapachol involves the inhibition of certain enzymes and signaling pathways, contributing to its potential therapeutic effects. It disrupts cellular respiration and affects redox balance, which can lead to the selective targeting of certain pathogenic organisms and cancer cells.

<p>6-Chloro didesacetyl famciclovir is a synthetic antiviral compound, which is derived from famciclovir, with specific modifications to enhance its biochemical properties. It is a chlorinated analog resulting from structural alterations to famciclovir, a prodrug of the antiviral agent penciclovir.</p>