Antiparassitari
Gli antiparassitari sono composti progettati per trattare e prevenire le infezioni parassitarie inibendo la crescita e la sopravvivenza dei parassiti. Questa categoria include una gamma di agenti antiparassitari destinati esclusivamente all'uso in laboratorio e non per il consumo umano. Questi prodotti sono essenziali per scopi di ricerca, consentendo agli scienziati di studiare i cicli di vita dei parassiti, i meccanismi d'azione e lo sviluppo della resistenza. L'uso di antiparassitari in ambienti di laboratorio aiuta nella scoperta e nell'ottimizzazione di nuovi trattamenti per le malattie parassitarie, contribuendo ai progressi nella parassitologia medica e veterinaria. I ricercatori si affidano a questi prodotti per migliorare la comprensione delle infezioni parassitarie e sviluppare terapie più efficaci.
Trovati 703 prodotti di "Antiparassitari"
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GNF179
CAS:GNF179 is an optimized 8,8-dimethyl IP analog.Formula:C22H23ClFN5OPurezza:98.9%Colore e forma:SolidPeso molecolare:427.9Ref: TM-T15409
1mg115,00€2mgPrezzo su richiesta5mg274,00€10mg454,00€25mg750,00€50mg1.026,00€100mg1.406,00€1mL*10mM (DMSO)303,00€Doxycycline monohydrate
CAS:Doxycycline monohydrate is an inhibitor of metalloproteinase (MMP)Formula:C22H26N2O9Purezza:99.97%Colore e forma:SolidPeso molecolare:462.4Sulfadiazine
CAS:Sulfadiazine, a short-acting sulfonamide, blocks bacterial folic acid synthesis; used with pyrimethamine to treat toxoplasmosis in AIDS, newborns.Formula:C10H10N4O2SPurezza:99.32%Colore e forma:White To Slightly Yellow Crystalline PowderPeso molecolare:250.28Antimalarial agent 33
Antimalarial agent 33 (compound 5g) exhibits antiplasmodial activity targeting both erythrocytic and hepatic stages of Plasmodium, with an effectivePurezza:98%Colore e forma:Odour SolidAlkaline tryptase-IN-1
Alkaline tryptase-IN-1 (compound H-13) is an insecticide that targets alkaline trypsin-like enzymes. It has lethal concentration (LC50) values of 8.72, 13.77, 14.17, 12.96, and 12.35 μg/mL against Schizaphis graminum, Sitobion avenae, Brevicoryne brassicae, Aphis gossypii, Aphis spiraecola, and Myzus persicae, respectively.Formula:C29H33BrN2O2SColore e forma:SolidPeso molecolare:553.55TSO-13
<p>TSO-13 is an inhibitor of the major cysteine protease Cruzipain found in Trypanosoma cruzi, with an IC50 of 2.2 μM. In Vero cells, TSO-13 also suppresses T. cruzi, exhibiting an IC50 of 1.9 μM.</p>Formula:C32H36N4O4S2Colore e forma:SolidPeso molecolare:604.78NPD-2975
NPD-2975 (compound 30) is an orally active antitrypanosomal agent effective against Human African Trypanosomiasis (HAT), demonstrating acceptable metabolicFormula:C14H13FN4OPurezza:98%Colore e forma:SolidPeso molecolare:272.28DCN-83
DCN-83, a potent anti-leishmanial compound, exhibits its highest efficacy against the amastigote form, achieving an IC50 value of 0.71 μM.Formula:C20H18BrN3SPurezza:98%Colore e forma:SolidPeso molecolare:412.35Antileishmanial agent-21
Antileishmanial agent-21 (compound 4e) functions as an inhibitor of Leishmania pteridine reductase 1 (Lm-PTR1), employing an anti-folate mechanism.Formula:C21H16N2O3Purezza:98%Colore e forma:SolidPeso molecolare:344.36Antitrypanosomal agent 16
Antitrypanosomal agent 16 functions as a potent trypanocide, exhibiting an inhibitory concentration 50 (IC50) of 0.04μM against the T.Purezza:98%Colore e forma:Odour SolidAntitrypanosomal agent 17
Compound 17 (Compd 7a) exhibits potent antiamastigote activity, demonstrated by its IC50 value of 0.03 μM against the T. congolense strain IL3000 [1].Purezza:98%Colore e forma:Odour SolidHAT-IN-8
HAT-IN-8 (Compound 38), a blood-brain barrier-permeable inhibitor of Trypanosoma brucei with an EC50 of 0.18 μM, is utilized in the study of Human AfricanFormula:C14H15F2N3O2SPurezza:98%Colore e forma:SolidPeso molecolare:327.35Antitrypanosomal agent 13
Compound 4b (antitrypanosomal agent 13) is a potent antitrypanosomal with notable trypanocidal and cytotoxic activities, exhibiting GI50 values of 0.18 μMFormula:C47H81N2NaO10SPurezza:98%Colore e forma:SolidPeso molecolare:889.21Antiparasitic agent-17
Antiparasitic Agent-17 (compound 5u), an orally active antiparasitic, demonstrates inhibition against both Chloroquine-sensitive (Pf3D7) and Chloroquine-Formula:C32H30N2O4Purezza:98%Colore e forma:SolidPeso molecolare:506.59AAP4
AAP4 is a potent inhibitor of OfChi-h and OfHex1, exhibiting Ki values of 29.3 nM and 4.9 μM, respectively. It also demonstrates insecticidal activity against the lepidopteran pest Ostrinia furnacalis.Formula:C21H23BrClN7Colore e forma:SolidPeso molecolare:488.811Antimalarial agent 31
Compound 31 (compound 7k) is an orally active inhibitor of Plasmodium falciparum aspartic protease, plasmepsin X (PMX), with antimalarial properties [1].Formula:C36H47N3O4Purezza:98%Colore e forma:SolidPeso molecolare:585.78CpNMT-IN-1
<p>CpNMT-IN-1 (Compound 11e) is an inhibitor of N-myristoyltransferase (CpNMT) with an IC50 value of 2.5 μM. It also inhibits the growth of microsporidia, demonstrating an EC50 value of 6.9 μM.</p>Formula:C25H25ClN4O4SColore e forma:SolidPeso molecolare:513.008LASSBio-1985
LASSBio-1985 is an inhibitor of NHLd (nucleoside hydrolase of Leishmania donovani), with a Ki of 79 μM and an IC50 of 84.6 μM. It exhibits selective toxicity against Leishmania parasites without affecting mammals, showing potential for research in infectious disease treatment.Formula:C18H22N2O7Colore e forma:SolidPeso molecolare:378.38Antitrypanosomal agent 23
Antitrypanosomal agent 23 is an antiparasitic compound effective against intracellular amastigotes of Trypanosoma cruzi in LLC-MK2 and C2C12 cells, demonstrating activity with IC50 values of 0.10 and 0.11 μM, respectively. It also acts as a weak inhibitor of recombinant Trypanosoma cruzi sialyltransferase (TcTS) with an IC50 of 1.1 mM.Formula:C14H16N4O7Colore e forma:SolidPeso molecolare:352.1019Notrilobolide
CAS:Notrilobolide, an alkaloid with insecticidal properties, is isolated from sweet potatoes and impedes larval development in pests such as Tribolium castaneum.Formula:C26H36O10Purezza:98%Colore e forma:SolidPeso molecolare:508.56Emoquine-1
Emoquine-1 is a potent orally active antimalarial agent effective against various drug-resistant Plasmodium strains, including artemisinin-resistant dormant parasites. It demonstrates efficacy against proliferative malignant Plasmodium with an IC50 value ranging from 20 to 55 nM. Emoquine-1 holds potential for treating Plasmodium strains resistant to artemisinin combination therapy (ACT), with the capability to eradicate persistent parasites.Formula:C30H28ClN3O6Colore e forma:SolidPeso molecolare:562.013Norselic acid B
CAS:Norselic acid B is a naturally occurring compound that can be isolated from the sponge Crella sp. collected in Antarctica. It demonstrates activity against Leishmania parasites.Formula:C29H44O4Colore e forma:SolidPeso molecolare:456.657Antimalarial agent 47
<p>Antimalarial agent 47 (compound F14) is a chemical compound effective against Plasmodium falciparum, specifically targeting the W2 strain with an IC50 value of 235 nM.</p>Formula:C16H14ClF2NOColore e forma:SolidPeso molecolare:309.74Antimalarial agent 28
<p>Antimalarial agent 28 (Compound 2i) acts as an antiplasmodial agent, exhibiting inhibition of P.</p>Formula:C27H25ClFN3O2Purezza:98%Colore e forma:SolidPeso molecolare:477.96Cysteine protease inhibitor-3
Cysteine protease inhibitor-3 (Compound 15), a cysteine protease inhibitor, exhibits anti-plasmodial activity, effectively inhibiting Pf3D7 (IC50 = 0.74 μM),Formula:C26H22ClF2N3OPurezza:98%Colore e forma:SolidPeso molecolare:465.92Antiproliferative agent-56
Antiproliferative agent-56 (Compound 31) is an antimalarial agent that inhibits the Pf3D7 strain of the malaria parasite Plasmodium falciparum with an IC50 of >12.5 (48h) and 0.03 μM (98h), displaying slow-acting characteristics.Colore e forma:Odour SolidSarolaner
CAS:Sarolaner (PF-6450567) is an orally active and broad-spectrum ectoparasiticide (LC80: 0.3 μg/mL against C. felis and an LC100: 0.003 μg/mL against O. turicata).Formula:C23H18Cl2F4N2O5SPurezza:99.54% - 99.65%Colore e forma:SolidPeso molecolare:581.36Antiparasitic agent-26
<p>Antiparasitic agent-26 (Compound 8) is an antiparasitic compound that effectively inhibits the growth of Naegleria fowleri, with an IC50 of 22.87 μM (trophozoite stage) and 25.16 μM (cyst stage). It exerts its antiparasitic effects by inducing programmed cell death, which includes cytosolic calcium accumulation, mitochondrial membrane potential collapse, ATP synthesis inhibition, ROS accumulation, and chromatin condensation. Antiparasitic agent-26 can be utilized in research on primary amoebic meningoencephalitis (PAM).</p>Colore e forma:Odour SolidAntitrypanosomal agent 12
Antitrypanosomal agent 12, a C20-phenylthiourea, exhibits trypanocidal and cytotoxic activities, demonstrating antitrypanosomal activity with GI50 values of 0.Formula:C49H77N2NaO10SPurezza:98%Colore e forma:SolidPeso molecolare:909.2Nitroxynil
CAS:Nitroxynil is an anthelmintic for adult/immature parasites, mainly used in Fasciola hepatica studies.Formula:C7H3IN2O3Purezza:99.76%Colore e forma:SolidPeso molecolare:290.01Antileishmanial agent-25
Antileishmanial agent-25 (compound 24) exhibits selective activity against intracellular amastigotes, demonstrating an inhibitory concentration (IC50) of 6.63Purezza:98%Colore e forma:Odour SolidAntimalarial agent 43
Antimalarial agent 43 (compound 16c) is an antimalarial compound that exhibits an IC50 value of 0.0151 μM against the 3D7 strain.Colore e forma:Odour SolidAntimalarial agent 27
Antimalarial agent 27 (compound 11a) potently inhibits P.Formula:C10H11NNaO5PPurezza:98%Colore e forma:SolidPeso molecolare:279.16Antileishmanial agent-19
<p>Compound F27 (Antileishmanial agent-19) is an antileishmanial compound effective against L.</p>Formula:C22H18N4O3Purezza:98%Colore e forma:SolidPeso molecolare:386.48304-vs
8304-vs is a macrocyclic anti-Plasmodial compound that irreversibly binds to and inhibits the Plasmodium proteasome, effectively halting the growth ofFormula:C35H53N5O8SPurezza:98%Colore e forma:SolidPeso molecolare:703.89Antileishmanial agent-20
Antileishmanial agent-20 exhibits selectivity against the Leishmania parasite, with IC50 values of 2.8 μM for L.Formula:C15H16N4O3Purezza:98%Colore e forma:SolidPeso molecolare:300.31Anti-inflammatory agent 40
Anti-inflammatory agent 40 is a promising, orally-active compound with anti-malarial and anti-inflammatory properties.Formula:C30H24Cl2N2O4Purezza:98%Colore e forma:SolidPeso molecolare:547.43Anticancer agent 140
<p>Compound 140 (Compd 3) exhibits potential anticancer and antiparasitic activities [1].</p>Formula:C20H26N2OPurezza:98%Colore e forma:SolidPeso molecolare:310.43Morantel tartrate
CAS:Morantel tartrate (CP-12009-18 tartrate) is an antinematodal agent used mainly for livestock.Formula:C16H22N2O6SPurezza:98.08%Colore e forma:White Or Pale Yellow Crystalline PowderPeso molecolare:370.42Antileishmanial agent-24
Antileishmanial agent-24 (compound 33) exhibits antileishmanial activity, demonstrating an inhibitory concentration 50 (IC50) value of 5.39 μM againstFormula:C34H29Cl4N3O2Purezza:98%Colore e forma:SolidPeso molecolare:653.42MCG-02
MCG-02 is an inhibitor of cruzain (CRZ) and cathepsin L-like protease (CATL), capable of inhibiting CRZ in Trypanosoma cruzi and CATL in Trypanosoma brucei, with IC50 values of 0.2 μM and 0.02 μM, respectively.Formula:C13H13N3O2SColore e forma:SolidPeso molecolare:275.33Amprolium
CAS:Amprolium is a veterinary coccidiostat that interferes with THIAMINE metabolism.Formula:C14H19N4·ClPurezza:98%Colore e forma:SolidPeso molecolare:278.79Cordysinin C/D
CAS:Cordysinin C/D (compound 9) is a potential antimalarial agent that effectively inhibits the Plasmodium falciparum 3D7 strain.Formula:C13H12N2OColore e forma:SolidPeso molecolare:212.25Methylclonazepam
CAS:Methylclonazepam is a benzodiazepine with anxiolytic properties. It inhibits the uptake of 5-hydroxytryptamine by Schistosoma mansoni, and its derivatives exhibit anti-Schistosoma mansoni activity.Formula:C16H12ClN3O3Colore e forma:SolidPeso molecolare:329.74Anti-Trypanosoma cruzi agent-6
Anti-Trypanosoma cruzi agent-6 (Compound 8) exhibits inhibitory activity against Trypanosoma cruzi. It effectively suppresses the epimastigote, trypomastigote, and amastigote forms of T. cruzi, with IC50 values of 24.7 µM, 1.8 µM, and 1.6 µM, respectively.Formula:C19H20N2O5Colore e forma:SolidPeso molecolare:356.37CpCDPK1/TgCDPK1-IN-2
CAS:<p>CpCDPK1/TgCDPK1-IN-2 is a dual inhibitor of CpCDPK1 and TgCDPK1 with IC50 values of 12 and 5 nM for CpCDPK1 and TgCDPK1, respectively.CpCDPK1/TgCDPK1-IN-2 can</p>Formula:C20H21N5OPurezza:99.12%Colore e forma:SoildPeso molecolare:347.41Antimalarial agent 46
CAS:Antimalarial agent 46 (Compound 42a) is a compound with antimalarial activity, effective in inhibiting P. falciparum lines.Formula:C21H17Cl3N4OColore e forma:SolidPeso molecolare:447.75Antileishmanial agent-31
CAS:Antileishmanial agent-31 (Compound p1) is a pyrazole derivative exhibiting antileishmanial activity with an IC50 of 35.53 μg/mL. Furthermore, Antileishmanial agent-31 demonstrates high stability and is applicable in studies focused on leishmaniasis treatment.Formula:C11H11ClN2Colore e forma:SolidPeso molecolare:206.674-(2-Aminoethyl)amino-7-chloroquinoline
CAS:4-(2-Aminoethyl)amino-7-chloroquinoline (N1-(7-Chloroquinolin-4-yl)ethane-1,2-diamine) has potential anthelmintic and antitumor activity for the study ofFormula:C11H12ClN3Purezza:98.53%Colore e forma:SolidPeso molecolare:221.69Se2h
Se2h is a cruzain inhibitor exhibiting potent activity against intracellular amastigotes of Trypanosoma cruzi (EC50< 1 μM, SI> 10), with an inhibitory effect on cruzain of IC50< 100 nM (SI> 5.55). Compared to Benznidazole and cruzain inhibitor K777, Se2h shows superior selectivity and inhibition while its selenazole structure reduces selenium-related toxicity. Se2h demonstrates antiparasitic activity and holds promise for Chagas disease research.Formula:C12H13ClN4O2SeColore e forma:SolidPeso molecolare:359.67Antiparasitic agent-20
Antiparasitic Agent-20 (Compound 1p) exhibits broad-spectrum activity as a parasitic inhibitor, demonstrating efficacy against T.Purezza:98%Colore e forma:Odour SolidNanaomycin A
CAS:Nanaomycin A, a quinone antibiotic, reactivates cancer suppressor genes and inhibits DNMT3B (IC50=500nM).Formula:C16H14O6Purezza:98%Colore e forma:SolidPeso molecolare:302.28SpdSyn binder-1
CAS:SpdSyn binder-1 weakly inhibits malaria by binding to Plasmodium falciparum's spermidine synthase. Used for research.Formula:C21H22N4OPurezza:99.5%Colore e forma:SolidPeso molecolare:346.43ML251
CAS:ML251, potent inhibitor, targets T. brucei PFK (IC50=0.37μM) & T. cruzi PFK (IC50=0.13μM), aids parasite research.Formula:C17H13Cl2N3O4SPurezza:99.87%Colore e forma:SolidPeso molecolare:426.27Ref: TM-T64320
1mg115,00€5mg274,00€10mg432,00€25mg715,00€50mg1.008,00€100mg1.359,00€200mg1.825,00€1mL*10mM (DMSO)301,00€Antileishmanial agent-30
Compound 17k, also known as Antileishmanial agent-30, effectively inhibits Leishmania with an IC50 of 0.2 μM for L. donovani. It exhibits a CC50 of >100 μM and an SI of >500, indicating significant selectivity and potency.Formula:C23H21N5O2Colore e forma:SolidPeso molecolare:399.45PfSUB1-IN-1
<p>PfSUB1-IN-1 (compound 4c) is an inhibitor of Plasmodium falciparum subtilisin-like serine protease 1 (PfSUB1), exhibiting potent activity with an IC50 value of 15 nM. PfSUB1 is a key target in antimalarial research. PfSUB1-IN-1 demonstrates a 13-fold greater inhibitory effect on the growth of transgenic Plasmodium falciparum strains (expressing lower levels of PfSUB1 compared to the wild-type) than on wild-type parasite strains.</p>Colore e forma:Odour SolidAmitraz
CAS:Amitraz (NSC 324552): white monoclinic crystals, mp 86-87°C, water-insoluble, used as acaricide and in canine demodectic mange.Formula:C19H23N3Purezza:99.88%Colore e forma:White/Pale Yellow Crystalline SolidPeso molecolare:293.413-Deoxyaphidicolin
CAS:3-Deoxyaphidicolin is a phytotoxin that inhibits root growth in lettuce seedlings. Additionally, 3-Deoxyaphidicolin exhibits inhibitory activity against the protozoan parasites Leishmania major and Leishmania braziliensis.Formula:C20H34O3Colore e forma:SolidPeso molecolare:322.48Antimalarial agent 42
Compound 42 (Compound 2), an antimalarial agent, effectively inhibits Plasmodium falciparum during the asexual blood stages (IC 50 <0.5μM) and gametocytes (IC 50 is 0.14 μM).Formula:C24H42N2Colore e forma:SolidPeso molecolare:358.6LL-37 FK-13 TFA
LL-37 FK-13 TFA, the TFA salt form of LL-37 FK-13, is an antimicrobial agent that inhibits Trichomonas vaginalis. It exhibits minimal hemolytic effects on human red blood cells and shows slight cytotoxicity towards human fibroblasts.Colore e forma:Odour SolidMMV1634566
MMV1634566 is an effective antimalarial agent that can inhibit Plasmodium falciparum and exhibits cytotoxicity.Colore e forma:Odour SolidAChE-IN-66
Nematicidal Agent 1 is an effective nematicide that binds to the pocket of acetylcholinesterase (AChE).Colore e forma:Odour SolidBitoscanate
CAS:Bitoscanate (PDITC) is used in the treatment of hookworms.Formula:C8H4N2S2Purezza:98.32%Colore e forma:Colorless Needles Bitoscanate Is An Odorless Colorless Crystals Melting Point 132°CPeso molecolare:192.26Eflornithine
CAS:Eflornithine blocks ornithine decarboxylase, treating African trypanosomiasis and female facial hair.Formula:C6H12F2N2O2Purezza:99.44% - 99.84%Colore e forma:SolidPeso molecolare:182.17β-Hederin
CAS:β-Hederin has antileishmanial activity. β-Hederin has apoptotic effect on cancer cells, it could be a promising candidate for chemotherapy of breast cancer.Formula:C41H66O11Purezza:98%Colore e forma:SolidPeso molecolare:734.96Cinchonidine
CAS:Cinchonidine (L-Cinchonidine) is an alkaloid extracted from Cinchona officinalis. It is a pseudo-enantiomer and stereoisomer of cinchonine.Formula:C19H22N2OPurezza:94.96% - 99.87%Colore e forma:White PowderPeso molecolare:294.39Insecticidal agent 24
Insecticidal agent 24 is an orally active pyridinyl spiroindoline lead compound. It demonstrates antimalarial activity with Pf NF54IC50 of 0.08 μM. Insecticidal agent 24 also inhibits hERG activity with an IC50 of 6.5 μM. In a humanized immunodeficient NSG mouse model of malaria infection, it effectively reduces parasitemia.Formula:C26H29N3O2Colore e forma:SolidPeso molecolare:415.22598JC-229
CAS:JC-229 is a potent and selective TbRPA1 inhibitor that can inhibit RPA1 in Trypanosoma brucei. JC-229 can be used to study human African Trypanosomiasis (HAT).Formula:C20H14Cl4N2O3SPurezza:97.13%Colore e forma:SolidPeso molecolare:504.21pCDPK1/TgCDPK1-IN-3
CAS:CpCDPK1/TgCDPK1-IN-3 inhibits Cp/TgCDPK1; IC50: 0.003/0.0036 µM. It's used to research Toxoplasma, Cryptosporidium diseases.Formula:C17H18N6Purezza:98.13%Colore e forma:SoildPeso molecolare:306.36Urethane
CAS:Urethane (Ethylurethane) was an antineoplastic agent .Now is used for other medicinal purposes.Formula:C3H7NO2Purezza:99.01%Colore e forma:SoildPeso molecolare:89.09Cletoquine
CAS:<p>Cletoquine, Hydroxychloroquine's active metabolite, fights CHIKV, has antimalarial properties, and may treat autoimmune diseases.</p>Formula:C16H22ClN3OPurezza:99.95% - 99.98%Colore e forma:SolidPeso molecolare:307.821,2-Dimethyl-1H-benzo[d]imidazole
CAS:1,2-Dimethyl-1H-benzo[d]imidazole has antibacterial activity against Entamoeba histolytica and Giardia lamblia,Formula:C9H10N2Purezza:99.86%Colore e forma:SolidPeso molecolare:146.19Antimalarial agent 13
CAS:Antimalarial agent 13 (N2-(3-chlorophenyl)-N4-(furan-2-ylmethyl)quinazoline-2,4-diamine) is a potent antimalarial agent.Formula:C19H15ClN4OPurezza:99.15%Colore e forma:SolidPeso molecolare:350.8Ref: TM-T9984
1mg89,00€5mg173,00€10mg259,00€25mg393,00€50mg552,00€100mg738,00€200mg979,00€1mL*10mM (DMSO)183,00€N-Methyl-1,3-benzoxazol-2-amine
CAS:N-Methyl-1,3-benzoxazol-2-amine, with CAS No. 19776-98-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. N-Methyl-1,3-benzoxazol-2-amine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C8H8N2OColore e forma:SoildPeso molecolare:148.1616Antileishmanial agent-33
Antileishmanial agent-33 (4e) is a hybrid compound of grandisin and machilin G, demonstrating moderate activity against promastigotes with an IC50 of 38.1 μM. In studies of cutaneous leishmaniasis (CL), Antileishmanial agent-33 (4e) has shown potential as an antileishmanial agent.Colore e forma:Odour SolidBiotin-PEG3-Mal
CAS:Biotin-PEG3-Mal (Biotin-PEG3-NH-Mal) is a biotin-labeled PROTAC linker belonging to the PEG class that can be used to synthesize PROTAC molecules.Formula:C25H39N5O8SPurezza:99.5%Colore e forma:SolidPeso molecolare:569.67Antimalarial agent 45
Antimalarial agent 45 (compound 8I) is an antimalarial with activity against Plasmodium parasites, exhibiting an IC50 of 0.21 μM. It is used in the study of malaria.Formula:C33H34N4O3Colore e forma:SolidPeso molecolare:534.65Proteasome-IN-6
Proteasome-IN-6 (Compound J-80) inhibits the β5 catalytic subunit of the Trypanosoma brucei 20S proteasome, effectively blocking T. b. brucei, T. b. gambiense, and T. b. rhodesiense with EC50 values of 157 nM, 220 nM, and 156 nM, respectively. Additionally, Proteasome-IN-6 has demonstrated antitrypanosomal activity in a mouse model.Formula:C35H45F3N4O6Colore e forma:SolidPeso molecolare:674.754-(Trifluoromethyl)nicotinic acid
CAS:Compound FL0181, with CAS No. 158063-66-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound FL0181 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formula:C7H4F3NO2Purezza:98%Peso molecolare:191.11Modoflaner
CAS:Modoflaner is an antiparasitic (veterinary use).Formula:C23H10F12IN3O2Purezza:98.78%Colore e forma:SolidPeso molecolare:715.23Ile-AMS TFA
Ile-AMS TFA exhibits activity against P. falciparum, with an ABSIC50 value of 1.19 nM.Formula:C18H27F3N8O8SColore e forma:SolidPeso molecolare:572.52Pyronaridine tetraphosphate
CAS:Pyronaridine tetraphosphate is a DNA topoisomerase 2 inhibitor with antimalarial and antitumor activity for the treatment of P. falciparum infection.Formula:C29H44ClN5O18P4Purezza:99.82%Colore e forma:SolidPeso molecolare:910.03ACT-451840
CAS:ACT-451840 eliminates both sensitive and resistant strains of Plasmodium falciparum and has the advantages of oral, potency, low toxicity, rapid.Formula:C47H54N6O3Purezza:96.07%Colore e forma:SolidPeso molecolare:750.97Ref: TM-T203012
1mg114,00€5mg242,00€10mg386,00€25mg739,00€50mg1.184,00€100mg1.794,00€1mL*10mM (DMSO)252,00€Febrifugine dihydrochloride
CAS:Febrifugine dihydrochloride (Propyldazine hydrochloride) is a biochemical with therapeutic activity regarding malaria, cancer, fibrosis and inflammatoryFormula:C16H21Cl2N3O3Purezza:98.27% - 99.85%Colore e forma:SolidPeso molecolare:374.26Ref: TM-TN1012L
1mg52,00€2mg74,00€5mg111,00€10mg170,00€25mgPrezzo su richiesta50mgPrezzo su richiestaAzlocillin sodium salt
CAS:<p>Azlocillin sodium, an acylampicillin, is a broad-spectrum antibiotics</p>Formula:C20H22N5NaO6SPurezza:97.63% - 98.302%Colore e forma:SolidPeso molecolare:483.47Dixanthogen
CAS:Dixanthogen (Auligen) is an ectoparasiticide. Dixanthogen is a thiocarbonyl compound.Formula:C6H10O2S4Purezza:95% - 98%Colore e forma:SolidPeso molecolare:242.4Antitrypanosomal agent 15
Antitrypanosomal Agent 15 (Compound 26) is an orally active, brain-penetrant, selective inhibitor of the Trypanosoma cruzi proteasome, exhibiting a pIC50 of 7.4Formula:C21H19FN4O4Purezza:98%Colore e forma:SolidPeso molecolare:410.4Antiparasitic agent-22
Antiparasitic agent-22 (Compound 24) is a broad-spectrum antiparasitic compound that inhibits the procyclic form of T. brucei, L. infantum, and L. tropica with IC50 values of 2.41, 5.95, and 8.98 μM, respectively, and the amastigote form of L. infantum with an IC50 of 8.18 μM. It also shows inhibitory activity against the P. falciparum W2 strain with an IC50 of 0.155 μM. Additionally, Antiparasitic agent-22 exhibits low cytotoxicity in THP1 cells, with a CC50 of 64.16 μM.Formula:C18H20BrN3O3Peso molecolare:405.0688Longestin
CAS:Longestin, a specific phosphodiesterase (phosphodiesterase) inhibitor with antitrypanosomal activity, is derived from Streptomyces argenteolus. It is under investigation for its potential use in anti-amnesic medications.Formula:C61H88O17Peso molecolare:1093.34Human α-defensin 5
Human α-defensin 5 is an antiviral peptide that inhibits the infection of non-enveloped viruses such as AdV, HPV, and polyomaviruses, with an IC50 range of 0.6-Formula:C144H238N50O45S6Purezza:98%Colore e forma:SolidPeso molecolare:3582.13WJM280
WJM280 is an orally active antimalarial compound with an EC50 of 0.04 μM against the parasite P. falciparum 3D7.Formula:C22H25F3N2OColore e forma:SolidPeso molecolare:390.44Antiparasitic agent-25
Antiparasitic agent-25 (Compounds 11) is an orally active antiparasitic compound. It inhibits the invasion and replication capabilities of parasites and has an irreversible effect on Toxoplasma gondii. The agent significantly reduces the replication rate of Toxoplasma gondii, with an IC50 value of 6.33 μM, and exhibits low cytotoxicity, having a CC50 value of 285 μM.Colore e forma:Odour Solid4-Propylbenzene-1,2-diol
CAS:4-Propylbenzene-1,2-diol exhibits antimalarial activity and can inhibit Plasmodium falciparum,Formula:C9H12O2Purezza:98.84%Colore e forma:SolidPeso molecolare:152.19DXR-IN-1
DXR-IN-1 (Compound 13E) is an inhibitor of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR). It exhibits high selectivity for DXR of Plasmodium falciparum with an IC50 of 0.030 μM. DXR-IN-1 impedes the growth of Plasmodium by binding to the active site of DXR and inhibiting its catalytic activity.Formula:C19H24NO5PPeso molecolare:377.13921Antimalarial agent 49
Antimalarial agent 49 is an oral compound with antimalarial properties. It inhibits the growth of Pf3D7 and PfK1 strains, with IC50 values of 0.84 μM and 0.4 μM, respectively. Additionally, it demonstrates the ability to suppress the liver stage development of P. berghei and can be utilized in malaria infection research.Colore e forma:Odour SolidDodecamethylpentasiloxane
CAS:<p>Dodecamethylpentasiloxane can be used as a bed bug insecticide. Dodecamethylpentasiloxane is a component of siloxane and can be used as silicone oil.</p>Formula:C12H36O4Si5Purezza:97.43%Colore e forma:SolidPeso molecolare:384.84Antiparasitic agent-24
<p>Antiparasitic agent-24 (Compound 14a) is an antiparasitic compound with EC50 values of 0.005 μM for L. maj, 0.069 μM for L. don, 0.82 μM for T. brucei, and 4.1 μM for T. cruzi.</p>Formula:C23H22ClN7O2SColore e forma:SolidPeso molecolare:495.98Antileishmanial agent-26
Antileishmanial agent-26 (Compound 69) is a guanidine-containing compound with activity against *Leishmania donovani*, exhibiting an IC50 value of 5.67 μM and a CC50 value of 3.79 μM in THP-1 cells. This compound is applicable for research in tropical diseases.Formula:C23H27FN4O2Peso molecolare:410.2118CCOE-5
CCOE-5 is a chalcone derivative with antimalarial activity, exhibiting an IC50 of 1.4 μg/mL against P. falciparum (3D7) and an IC50 of less than 5 μg/mL against P. falciparum (INDO). CCOE-5 shows potential for research in the anti-infective domain.Formula:C34H31NO6Colore e forma:SolidPeso molecolare:549.61NMT-IN-3
NMT-IN-3 is an inhibitor of N-myristoyltransferase (NMT), displaying an IC50 of 38 mM against Plasmodium vivax NMT.Formula:C26H32N6O4Peso molecolare:492.2485
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