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Antiparassitari

Antiparassitari

Gli antiparassitari sono composti progettati per trattare e prevenire le infezioni parassitarie inibendo la crescita e la sopravvivenza dei parassiti. Questa categoria include una gamma di agenti antiparassitari destinati esclusivamente all'uso in laboratorio e non per il consumo umano. Questi prodotti sono essenziali per scopi di ricerca, consentendo agli scienziati di studiare i cicli di vita dei parassiti, i meccanismi d'azione e lo sviluppo della resistenza. L'uso di antiparassitari in ambienti di laboratorio aiuta nella scoperta e nell'ottimizzazione di nuovi trattamenti per le malattie parassitarie, contribuendo ai progressi nella parassitologia medica e veterinaria. I ricercatori si affidano a questi prodotti per migliorare la comprensione delle infezioni parassitarie e sviluppare terapie più efficaci.

Trovati 699 prodotti di "Antiparassitari"

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  • MED6-189

    CAS:
    MED6-189, an analog of kalihinol, disrupts the apicoplast functions and vesicular transport in the malignant malaria parasite (P. falciparum, IC50 < 50 nM). The compound specifically targets the apicoplast, which is a non-photosynthetic plastid essential for isoprenoid synthesis, found in most apicomplexan parasites.
    Formula:C17H26N2O
    Colore e forma:Solid
    Peso molecolare:274.40
  • SPB07935

    CAS:
    SPB07935 inhibits plasmepsin II in the malaria-causing parasite Plasmodium falciparum and serves as an antimalarial agent. It affects the life cycle of P. falciparum, hindering the growth of the parasite's FcB1 and 3D7 strains, with IC50 values of 8 μM and 4.7 μM, respectively.
    Formula:C22H15N5O4S2
    Colore e forma:Solid
    Peso molecolare:477.516
  • Erythromycin B

    CAS:
    <p>Erythromycin B exhibits antimalarial activity by effectively inhibiting the asexual growth of Plasmodium falciparum.</p>
    Formula:C37H67NO12
    Colore e forma:Solid
    Peso molecolare:717.93
  • VNI

    CAS:
    <p>VNI is an effective inhibitor of CYP51. It suppresses sterol synthesis in Trypanosoma cruzi, exhibiting anti-Trypanosoma cruzi activity.</p>
    Formula:C26H19Cl2N5O2
    Colore e forma:Solid
    Peso molecolare:504.37
  • Ipronidazole

    CAS:
    Ipronidazole (RO-71554) is an orally effective antiprotozoal agent used to prevent and ameliorate histomoniasis in turkeys, commonly referred to as blackhead disease.
    Formula:C7H11N3O2
    Colore e forma:Solid
    Peso molecolare:169.18
  • Ferrocene

    CAS:
    Ferrocene, a crucial structural core in bioorganometallic chemistry, is renowned for its intrinsic stability, excellent oxygen reduction capabilities, and low toxicity. It also exhibits antimalarial and anticancer properties.
    Formula:C10H10Fe
    Colore e forma:Solid
    Peso molecolare:186.03
  • SLU-10906

    CAS:
    SLU-10906 (Compound 63) is an orally active inhibitor of Cryptosporidium. It demonstrates activity against the parasite in cell-based infection models with an EC50 of 0.19 μM and exhibits no cytotoxicity. SLU-10906 is a promising candidate for research in cryptosporidiosis.
    Formula:C22H21BFN5O2
    Colore e forma:Solid
    Peso molecolare:417.244
  • Antimalarial agent 48

    CAS:
    <p>Antimalarial agent 48 (Compound 15a) is a triazine compound with antimalarial activity, showing effectiveness against Plasmodium falciparum K1 and Plasmodium falciparum FCR3 with IC50 values of 280 and 290 nM, respectively. It holds promise for research in the field of anti-infective treatments.</p>
    Formula:C19H14F3N11
    Colore e forma:Solid
    Peso molecolare:453.383
  • LN002

    CAS:
    <p>LN002 is an orally active inhibitor of Cryptosporidium oxidase, utilized for research in cryptosporidiosis.</p>
    Formula:C22H15N7
    Colore e forma:Solid
    Peso molecolare:377.40
  • Menoctone

    CAS:
    Menoctone is an orally effective antimalarial agent that inhibits blood-induced rodent malaria. It enhances the antimalarial effects of chloroquine or quinine, making it useful for malaria research.
    Formula:C24H32O3
    Colore e forma:Solid
    Peso molecolare:368.51
  • NEU-1017

    CAS:
    <p>NEU-1017 serves as a broad-spectrum antiparasitic compound, effectively inhibiting T. brucei, L. major, and P. falciparum with EC50 values of 210 nM, 240 nM, and 3 nM, respectively.</p>
    Formula:C33H31ClFN5O3S
    Colore e forma:Solid
    Peso molecolare:632.147
  • Insecticidal agent 16

    CAS:
    Insecticidal agent 16 (compound A21) exhibits insecticidal activity against Plutella xylostella, with LC50 values of 1.2 and 13.2 µg/mL respectively.
    Formula:C21H13Cl2F6N5O2S
    Colore e forma:Solid
    Peso molecolare:584.32
  • Etofamide

    CAS:
    Etofamide, an antimicrobial agent, exhibits an IC50 of 5.96 mg/L against amoebae.
    Formula:C19H20Cl2N2O5
    Colore e forma:Solid
    Peso molecolare:427.28
  • MMV03

    CAS:
    <p>MMV03 is an antimalarial compound effective against Plasmodium falciparum, with an EC50 of 0.6 μM.</p>
    Formula:C19H14N4OS
    Colore e forma:Solid
    Peso molecolare:346.406
  • PfCLK3-IN-1


    <p>PfCLK3-IN-1 (Compound 4) serves as a covalent inhibitor of the malaria parasite CLK3 (Pf CLK3) under alkaline conditions, with a pEC50 of 7.1. It inhibits the maturation of gametocytes during the sexual stage of the parasite, thereby hindering transmission. Additionally, PfCLK3-IN-1 effectively suppresses the Dd2-B2 clone of the malaria parasite, exhibiting an IC50 of 239.5 nM.</p>
    Formula:C28H27ClN4O4
    Colore e forma:Solid
    Peso molecolare:518.99
  • DNA crosslinker 6

    CAS:
    <p>DNA crosslinker 6 (compound 1) is an anti-mitotic agent known for its strong binding affinity to AT-DNA and inhibition of AT-hook 1 binding to DNA (IC50=0.03 µM). Additionally, it exhibits anti-protozoal activity, effectively inhibiting T. brucei with an EC50 of 0.83 µM.</p>
    Formula:C19H21N7O
    Colore e forma:Solid
    Peso molecolare:363.42
  • PIQ-2

    CAS:
    PIQ-2 (compound 54) serves as an antiprotozoal agent, displaying potent activity against IP. falciparum 3D7 and B. divergens Rouen, with IC50 values of 9.4 nM and 1.6 nM, respectively.
    Formula:C23H21F3N4O3
    Colore e forma:Solid
    Peso molecolare:458.43
  • 2-Phenazinamine,N,5-bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-

    CAS:
    Formula:C27H22Cl2N4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:473.3964

    Ref: IN-DA00I3TE

    ne
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  • Insecticidal agent 6

    CAS:
    <p>Compound Im (Insecticidal agent 6) is a potent inhibitor of insect ryanodine receptors (RyRs), exhibiting an EC50 of 0.6308 µM against S.</p>
    Formula:C19H14BrCl2N5O4
    Purezza:98%
    Colore e forma:Solid
    Peso molecolare:527.16

    Ref: TM-T82064

    5mg
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    50mg
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