Antiparassitari
Gli antiparassitari sono composti progettati per trattare e prevenire le infezioni parassitarie inibendo la crescita e la sopravvivenza dei parassiti. Questa categoria include una gamma di agenti antiparassitari destinati esclusivamente all'uso in laboratorio e non per il consumo umano. Questi prodotti sono essenziali per scopi di ricerca, consentendo agli scienziati di studiare i cicli di vita dei parassiti, i meccanismi d'azione e lo sviluppo della resistenza. L'uso di antiparassitari in ambienti di laboratorio aiuta nella scoperta e nell'ottimizzazione di nuovi trattamenti per le malattie parassitarie, contribuendo ai progressi nella parassitologia medica e veterinaria. I ricercatori si affidano a questi prodotti per migliorare la comprensione delle infezioni parassitarie e sviluppare terapie più efficaci.
Trovati 703 prodotti di "Antiparassitari"
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2,5-Diacetoxy-2,5-dihydrofuran (Mixture of Isomers) (>90%)
CAS:Prodotto controllato<p>Applications 2,5-Diacetoxy-2,5-dihydrofuran is used as a reagent to synthesize Mexicanin H, a biologically active sesquiterpene lactone that exhibits antiparasitic activity against Trypanosoma cruzi (a parasite that causes Chagas disease)<br>References Jimenez-Ortiz, V., et al.: Parasitology, 91, 170 (2005); Romo, J., et al.: Tetrahedron Lett., No vol. given, 1029 (1966)<br></p>Formula:C8H10O5Purezza:>90%Colore e forma:NeatPeso molecolare:186.162-Hydroxy-1-methyl-9,10-anthracenedione
CAS:Prodotto controllatoFormula:C15H10O3Colore e forma:NeatPeso molecolare:238.24Methyl 1-[[2-N-(5-Nitrothiazolyl)carboxamido]phenyl]-2,3,4- tri-O-acetyl-β-D-glucopyranuronate
CAS:Prodotto controllato<p>Applications An intermediate in the synthesis of the metabolite of Nitazoxanide.<br>References Honma, K., et al.: Chem. Pharm. Bull., 24, 394 (1976), Dubreuil, L., et al.: Antimicrob. Agents Chemother., 40, 2266 (1996), Stockis, A., et al.: Int. J. Clin. Pharmacol. Ther., 34, 349 (1996),<br></p>Formula:C23H23N3O13SColore e forma:YellowPeso molecolare:581.514,4'-Dimethyldiphenylamine
CAS:Prodotto controllato<p>Applications 4,4'-Dimethyldiphenylamine is a reagent used in the comparative studies of the analgesic and anti-inflammatory properties of N-phenylanthranilic acids and mefenamic acid, and the anti parasitic activities of some substituted diphenylamines.<br>References Izard-Verchere, C., et al.: Chimica Therapeutica, 6, 346 (1971)<br></p>Formula:C14H15NColore e forma:NeatPeso molecolare:197.282'-O-(2-Methoxyethyl)-5-methylcytidine (~90%)
CAS:Prodotto controllatoFormula:C13H21N3O6Purezza:~90%Colore e forma:NeatPeso molecolare:315.32p-Cyanoacetophenone
CAS:Prodotto controllato<p>Applications Used in the preparation of antimalarial isonitriles.<br>References Singh, C. et al.; Bioorgan. Med. Chem. Lett. 12, 2277 (2002)<br></p>Formula:C9H7NOColore e forma:NeatPeso molecolare:145.163,6-Bis(3,5-dimethyl-1H-pyrazol-1-yl)-1,2,4,5-tetrazine
CAS:Prodotto controllatoFormula:C28H38O19Colore e forma:NeatPeso molecolare:678.597-Amino-1,5-dihydro-5-imino-2,8-quinolinedione Hydrochloride
CAS:Prodotto controllato<p>Applications 7-Amino-1,5-dihydro-5-imino-2,8-quinolinedione is a quinoline derivative. The principle use of Quinoline is the preparation of 8-hydroxyquinoline (H953265), a versatile chelating agent and precursor to certain antimalarial and anticancer drugs.<br>References Pettit, G.R., et al.: J. Org. Chem., 33, 1089 (1968);<br></p>Formula:C9H8ClN3O2Colore e forma:NeatPeso molecolare:225.63N-Decylaminoethanol
CAS:Prodotto controllato<p>Applications Used in the antileishmanial activity of lipidic amino alcohols.<br>References Coimbra, E.: Chem. Biol. Drug Des. 75, 233 (2010).<br></p>Formula:C12H27NOColore e forma:NeatPeso molecolare:201.352-Acetamido-2-deoxy-4-O-(β-D-galactofuranosyl)-α,β-D-glucopyranose
CAS:Prodotto controllato<p>Applications Synthetic galactofuranose-containing oligosaccharides could be useful for the identification of strains of T. cruzi as well as for studies on the inhibition of the biosynthesis of these unique O-linked chains.<br>References Gallo-Rodriguez, C., et al.: J. Org. Chem., 61, 1886 (1996)<br></p>Formula:C14H25NO11Colore e forma:NeatPeso molecolare:383.348(E)-4-Hydroxycrotonoic Acid Ethyl Ester (~85%)
CAS:Prodotto controllato<p>Stability No Date Available<br>Applications (E)-4-Hydroxycrotonoic Acid Ethyl Ester is an intermediate in the preparation of unusual amino acids that are potential Michael acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors.<br>References Breuning, A., et al.: J. Med. Chem., 53, 1951 (2010);<br></p>Formula:C6H10O3Purezza:~85%Colore e forma:NeatPeso molecolare:130.14PBD-5,11-dione
CAS:Prodotto controllato<p>Applications PBD-5,11-dione (cas# 18877-34-4) is a useful research chemical.<br></p>Formula:C12H12N2O2Colore e forma:NeatPeso molecolare:216.244-(Aminomethyl)-cyclohexanone Hydrochloride
CAS:Prodotto controllato<p>Applications 4-(Aminomethyl)-cyclohexanone Hydrochloride is used to prepare dispiro-1,2,4-trioxolanes with antimalarial activities. It is also used to synthesize aminopyrimidines as SYK inhibitors useful in the treatment of SYK-mediated diseases.<br>References Tang, Y., et al.: Bioorg. Med. Chem. Lett., 17, 1260 (2007); Altman, M., et al.: PCT Int. Appl. (2011), WO 2011075515 A1 20110623<br></p>Formula:C7H13NO·HClColore e forma:NeatPeso molecolare:127.18 + 36.463-Aminopropionitrile (Stabilized with K2CO3)
CAS:Prodotto controllatoFormula:C3H6N2Colore e forma:NeatPeso molecolare:70.09Pseurotin A
CAS:Prodotto controllato<p>Applications Pseurotin A shows antiparasitic and anticancer activity. It exhibits inhibition towards IgE (immunoglobin E) production.<br>References Martinez-Luis, S. et al.: Nat. Prod. Comm., 7, 165 (2012); Bioorg. Med. Chem. Lett., 19, 1457 (2009);<br></p>Formula:C22H25NO8Colore e forma:NeatPeso molecolare:431.444-Methoxy-6-(2-phenylethyl)-2H-pyran-2-one
CAS:Prodotto controllato<p>Applications 4-Methoxy-6-(2-phenylethyl)-2H-pyran-2-one is a Kawain (K145490) derivative that is known to exhibit antimalarial and antituberculosis activities. 4-Methoxy-6-(2-phenylethyl)-2H-pyran-2-one has been identified as a lead compound for the dual treatment of malaria and leishmaniasis.<br>References McCracken, S.T., et al.: Bioorg. Med. Chem., 20, 1482 (2012); Elzaawely, A.A.. et al.: Food. Chem., 103, 486 (2007); Xuan, T.D., et al.: J. Natural. Med., 62, 188 (2008);<br></p>Formula:C14H14O3Colore e forma:NeatPeso molecolare:230.26α-(3,4-Diethoxyphenyl)-6,7-diethoxy-1-isoquinolinemethanol
CAS:Prodotto controllato<p>Applications α-(3,4-Diethoxyphenyl)-6,7-diethoxy-1-isoquinolinemethanol is an intermediate in synthesizing Ethaverine (E676700), which is an analogue of Papaverine (P190500), an antispasmodic. An isoquinoline derivative with the potential for antimicrobial, antimalarial and cytotoxic antiviral agents.<br>References Kaplan, D., et al.: Biochem. J., 201, 605 (1982), Hifnawy, M.S., et al.: Anal. Profiles Drug Subs., 17, 367 (1988); Iwasa, K. et al.: Bioorg. Med. Chem., 9, 2871 (2001);<br></p>Formula:C24H29NO5Colore e forma:NeatPeso molecolare:411.491,2-Diamino-2-methyl Propane
CAS:Prodotto controllato<p>Applications 1,2-Diamino-2-methyl Propane is a reactant used in the preparation of neocryptolepine analogs with antimalarial activity.<br>References Shaban, E., et. al.: Heterocycles, 89, 1055 (2014)<br></p>Formula:C4H12N2Colore e forma:NeatPeso molecolare:88.15Tizoxanide - 98%
CAS:Anti-parasitic; pyruvate ferredoxin oxidoreductase inhibitorFormula:C10H7N3O4SPurezza:Min. 95%Peso molecolare:265.01573Satranidazole
CAS:<p>Satranidazole is an antimicrobial agent that falls under the category of synthetic nitroimidazoles. It is derived from chemical synthesis and is designed to combat infections caused by specific organisms. The mode of action involves the reduction of the nitro group within the organism, creating reactive intermediates that disrupt DNA synthesis and lead to cell death. This mode of action is notably effective against protozoal infections and anaerobic bacterial infections.</p>Formula:C8H11N5O5SPurezza:Min. 95%Peso molecolare:289.27 g/molOxfendazole
CAS:<p>Oxfendazole is a benzimidazole anthelmintic with action on microtubule formation in parasitic worms and is used for treating gastrointestinal parasites in livestock.</p>Formula:C15H13N3O3SPurezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:315.35 g/mol4′-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethylavermectin A1a
CAS:4′-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethylavermectin A1a is a semi-synthetic derivative of avermectin, which is a naturally occurring compound isolated from the fermentation broth of the soil bacterium *Streptomyces avermitilis*. This compound exhibits potent antiparasitic activity by targeting the glutamate-gated chloride channels in the nervous systems of parasitic organisms. By binding and activating these channels, it increases the permeability of the cell membrane to chloride ions, resulting in paralysis and death of the parasite.Formula:C41H60O11Purezza:Min. 95%Peso molecolare:728.91 g/molPF 1022A
CAS:<p>PF 1022A is a cyclooctadepsipeptide, which is a type of cyclic peptide composed of amino acids and hydroxy acids. It is derived from the fermentation products of the fungus *Mycelia sterilia*, a member of the *Rosellinia* genus. Its mode of action involves disrupting glutamate-gated chloride channels in parasitic nematodes, which leads to paralysis and eventual death of the parasite.</p>Formula:C52H76N4O12Purezza:Min. 95%Peso molecolare:949.18 g/molIvermectin
CAS:Naturally produced by the soil bacterium Streptomyces avermitili, it is clinically used in the treatment of parasitosis in both humans and animals. Ivermectin is commercially available as a mixture of 80% 22, 23-dihydroavermectin B1a and 20% 22, 23-dihydroavermectin B1b. In 2020, Ivermectin indicated that it was a good antiviral agent in the treatment of SARS-CoV-2 and a new mechanism of action has been suggested. Ivermectin would act on importin α/β heterodimer and affect nuclear transport and the translocation of viral proteins.Formula:C48H74O14Purezza:85%MinPeso molecolare:875.1 g/molAmoscanate
CAS:Amoscanate is an antischistosomal agent, which is a synthetic compound with a broad spectrum of activity against parasitic infections. Its mode of action involves the disruption of parasite metabolism and structure, ultimately leading to the elimination of schistosomes. Schistosomes are trematode worms responsible for schistosomiasis, a significant parasitic disease affecting millions of people worldwide.Formula:C13H9N3O2SPurezza:Min. 95%Peso molecolare:271.3 g/molHalofuginone
CAS:Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.Formula:C16H17BrClN3O3Purezza:99.53%Colore e forma:Off-White SolidPeso molecolare:414.68Ref: TM-T6856
1mg37,00€5mg87,00€10mg123,00€25mg240,00€50mg363,00€100mg547,00€500mg1.198,00€1mL*10mM (DMSO)Prezzo su richiestaSymetine
CAS:Symetine（L 16726） is a small molecule compound with antiparasitic activity that can be used to study amoebic liver abscesses in guinea pigs.Formula:C30H48N2O2Purezza:99.79%Colore e forma:SolidPeso molecolare:468.71MMV006833
CAS:<p>MMV006833 is an inhibitor of Plasmodium falciparum. It targets the lipid transfer protein PfSTART1, inhibiting the ring-stage development of Plasmodium falciparum.</p>Formula:C19H27ClN2O4SColore e forma:SolidPeso molecolare:414.95Chalcone 4 hydrate
CAS:Chalcone 4 hydrate, an anti-parasite compound, inhibits the growth of Theileria and Babesia.Formula:C16H15ClO4Purezza:99.54%Colore e forma:SolidPeso molecolare:306.74BPH-715
CAS:BPH-715 inhibits the liver-stage growth of P. falciparum with an IC50 of 10 μM for P. falciparum exoerythrocytic forms in HepG2 cells.Formula:C17H31NO7P2Purezza:98.91%Colore e forma:SolidPeso molecolare:423.38Halofuginone hydrobromide
CAS:Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.Formula:C16H17BrClN3O3·HBrPurezza:97.01% - 99.73%Colore e forma:SolidPeso molecolare:495.59Ref: TM-T3524
1mg37,00€2mg52,00€5mg79,00€10mg112,00€25mg219,00€50mg328,00€100mg495,00€500mg947,00€1mL*10mM (DMSO)88,00€ICA
CAS:ICA (N-[4-(2-Pyridinyl)-2-thiazolyl]-2-pyridinamine) is a SK channel inhibitor and exhibits antileishmanial activity (IC50: 2.1 µM).Formula:C13H10N4SPurezza:99.68%Colore e forma:SolidPeso molecolare:254.31Ref: TM-T15546
1mg67,00€5mg123,00€10mg178,00€25mg286,00€50mg396,00€100mg553,00€200mg743,00€1mL*10mM (DMSO)172,00€CRK12-IN-2
CAS:<p>CRK12-IN-2, a potent CRK12 inhibitor, has EC50 of 3.2 nM for T. congolense and 0.08 nM for T. vivax; treats trypanosomiasis in animals.</p>Formula:C23H33F2N5O3S2Purezza:99.26% - 99.70%Colore e forma:SolidPeso molecolare:529.67Antimalarial agent 19
CAS:Compound 6e, an antimalarial, targets P. falciparum K1 (EC50 0.3 µM) and P. berghei (EC50 15.3 µM); has high solubility and stability.Formula:C22H33Cl2N5SPurezza:98%Colore e forma:SolidPeso molecolare:470.5(Z)-Tyrphostin A51
CAS:(Z)-Tyrphostin A51 is an isomer of Tyrphostin A51 exhibiting inhibitory activity against P. falciparum (IC₅₀≈10 μM).Formula:C13H8N4O3Colore e forma:Brown SolidPeso molecolare:268.23SQ109
CAS:SQ109 (NSC-722041) is an effective inhibitor of the trypomastigote form of the parasite (IC50 = 50 nM). SQ109 is an antitubercular agent and targets MmpL3.Formula:C22H38N2Purezza:99.70% - 99.91%Colore e forma:SolidPeso molecolare:330.55Ref: TM-T16925
1mg66,00€5mg140,00€10mg216,00€25mg462,00€50mg677,00€100mg938,00€500mg1.882,00€1mL*10mM (DMSO)157,00€Antimalarial agent 24
CAS:Compound 24 (Compound 7), an in vitro antimalarial agent, demonstrates inhibitory activity against the Plasmodium falciparum W2 strain with an IC50 of 0.81 μMFormula:C20H16N4O2Purezza:98%Colore e forma:SolidPeso molecolare:344.37Antimalarial agent 29
CAS:Compound 29 (also known as Compound 16) is an antimalarial agent that demonstrates inhibition of the P.Formula:C18H10ClF3N2Purezza:98%Colore e forma:SolidPeso molecolare:346.73(Rac)-ACT-451840
CAS:(Rac)-ACT-451840 is an isomer of ACT-451840 exhibiting antimalarial activity against Plasmodium falciparum NF54.Formula:C47H54N6O3Purezza:99.25%Colore e forma:SolidPeso molecolare:750.97Ref: TM-T23625
1mgPrezzo su richiesta2mg141,00€5mg228,00€10mg366,00€25mg725,00€50mg1.103,00€100mg1.696,00€200mg2.284,00€1mL*10mM (DMSO)252,00€Antitrypanosomal agent 2
CAS:Antitrypanosomal agent 2 shows potent and specific antiparasite activities against Trypanosoma brucei.Formula:C17H13N5O3Purezza:99.2%Colore e forma:SolidPeso molecolare:335.32Insecticidal agent 2
CAS:Insecticidal agent 2 (example 2) is an effective pesticide that significantly inhibits pest growth [1].Formula:C16H8ClF7N2O2Purezza:98%Colore e forma:SolidPeso molecolare:428.69Antileishmanial agent-14
CAS:Antileishmanial agent-14, a sulfuretin analog, exhibits potential activity against Leishmania donovani promastigotes (IC 50 = 4.1 μM) and inhibits infection byFormula:C23H26ClNO5Purezza:98%Colore e forma:SolidPeso molecolare:431.91Antimalarial agent 26
CAS:Antimalarial agent 26, a derivative of 1,4-naphthoquinones, demonstrates antimalarial properties through oral administration.Formula:C20H22N4O3Purezza:98%Colore e forma:SolidPeso molecolare:366.41Quinfamide
CAS:Quinfamide is a compound with the potential to treat tropical parasitic infections such as Amoebiasis and Helminthiasis.Formula:C16H13Cl2NO4Purezza:99.92%Colore e forma:SolidPeso molecolare:354.18Ref: TM-T16705
1mg50,00€5mg105,00€10mg156,00€25mg255,00€50mg368,00€100mg505,00€200mg692,00€1mL*10mM (DMSO)111,00€Antileishmanial agent-15
CAS:Antileishmanial agent-15 (compound 13c) exhibits potent activity against L.Formula:C28H39N5O4Purezza:98%Colore e forma:SolidPeso molecolare:509.64Epsiprantel
CAS:Epsiprantel is an orally active antiparasitic drug that inhibits various tapeworms, including Echinococcus granulosus (granular echinococcus), in dogs.Formula:C20H26N2O2Purezza:98.09%Colore e forma:SolidPeso molecolare:326.43Antiparasitic agent-18
CAS:Antiparasitic agent-18 (compound 3a) exhibits potent and selective antiprotozoal activity, demonstrating effective inhibition of T.Formula:C25H21N7OPurezza:98%Colore e forma:SolidPeso molecolare:435.48Phosphodiesterase-IN-1
CAS:Phosphodiesterase-IN-1 (Compound 7), a phosphodiesterase (PDE) inhibitor, exhibits anti-Plasmodium and antiproliferative activities. It effectively inhibits P. falciparum (strain 3D7) with an IC 50 value of 0.64 μM [1].Formula:C15H15FN4OColore e forma:SolidPeso molecolare:286.3Piperaquine
CAS:Piperaquine is a bisquinoline antimalarial compound and a companion compound to artemisinin.Formula:C29H32Cl2N6Purezza:98%Colore e forma:SolidPeso molecolare:535.51Rufigallol
CAS:<p>Rufigallol, an anthraquinone with six OH groups, induces DLC and fluoresces when aggregated, showing antimalarial effects with vitamin C and ketones.</p>Formula:C14H8O8Purezza:98.92% - 99.27%Colore e forma:SolidPeso molecolare:304.21JCP174
CAS:<p>JCP174 is a depalmitoylase inhibitor that enhances Toxoplasma host-cell invasion by targeting TgPPT1.</p>Formula:C12H12ClNO3Purezza:97.05%Colore e forma:SolidPeso molecolare:253.68Artelinic acid
CAS:Artelinic acid is an artemisinin analog with antimalarial activity and is used for the treatment of multi-drug resistant strains of Plasmodium falciparum.Formula:C23H30O7Purezza:97.49% - 97.69%Colore e forma:SolidPeso molecolare:418.48Ref: TM-T10378
1mg99,00€5mg235,00€10mg376,00€25mg707,00€50mg1.103,00€100mg1.568,00€200mg2.118,00€1mL*10mM (DMSO)303,00€UCT943
CAS:UCT943 is an inhibitor of Plasmodium falciparum PI4K (IC50 = 23 nM).Formula:C22H20F3N5OPurezza:99.87%Colore e forma:SolidPeso molecolare:427.42Ref: TM-T13246
1mg104,00€2mg158,00€5mg259,00€10mg375,00€25mg605,00€50mg815,00€100mg1.093,00€500mg2.195,00€1mL*10mM (DMSO)279,00€Antimalarial agent 30
CAS:Antimalarial agent 30 has anti-Plasmodium berghei liver stage parasite activity and antimalarial activity for the study of malarial infections.Formula:C18H11F3N2Purezza:99.83% - 99.90%Colore e forma:SolidPeso molecolare:312.29AP-C5
CAS:AP-C5 inhibits cGKII with a Pic50 of 7.2, useful in diarrheal disease research.Formula:C16H13N5Purezza:99.82%Colore e forma:SolidPeso molecolare:275.31Bithionol sulfoxide
CAS:Bithionol sulfoxide (Bithionoloxide) is a compound with inhibitory effects against parasites, inhibiting Fasciola hepatica and Schistosoma mansoni.Formula:C12H6Cl4O3SPurezza:98.76%Colore e forma:Off White To Tinch Pink Crystalline PowderPeso molecolare:372.05Brotianide
CAS:Brotianide (BAY-VA4059) has anthelmintic activity and is highly potent against liver fluke and gastric fluke infestations and can be used to treat acute,Formula:C15H10Br2ClNO2SPurezza:97.44% - 98.14%Colore e forma:SolidPeso molecolare:463.57Allopurinol riboside
CAS:Allopurinol riboside, an allopurinol metabolite, inhibits purine nucleoside phosphorylase in parasites with a Ki of 277 μM.Formula:C10H12N4O5Purezza:99.46% - 99.73%Colore e forma:SolidPeso molecolare:268.23Antileishmanial agent-16
CAS:Antileishmanial agent-16 (compound 14c), an anti-Leishmania agent, exhibits potent activity against Leishmania major promastigotes (IC50 = 0.59 µM) andFormula:C27H37N5O4Purezza:98%Colore e forma:SolidPeso molecolare:495.61DDD85646
CAS:DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.Formula:C21H24Cl2N6O2SPurezza:97.8% - 99.76%Colore e forma:SolidPeso molecolare:495.43Ref: TM-T27135
1mg96,00€5mg266,00€10mg399,00€25mg677,00€50mg940,00€100mg1.293,00€1mL*10mM (DMSO)290,00€Phylloflavan
CAS:Phylloflavan, an antileishmanial compound, exhibits an intracellular half maximal effective concentration (EC50) of 3.2 nM in RAW 264.7 cells and inhibits theFormula:C26H26O10Purezza:98%Colore e forma:SolidPeso molecolare:498.48Antileishmanial agent-17
CAS:Antileishmanial agent-17, a coumarin hybrid, exhibits potent antileishmanial activity (IC50 <0.78 μM) while proving non-toxic to normal VERO cells.Formula:C27H37N5O5Purezza:98%Colore e forma:SolidPeso molecolare:511.61ELQ-596
CAS:ELQ-596, a quinolone derivative, exhibits antimicrobial activity against several protozoan parasites, including the intraerythrocytic parasites Plasmodium and Babesia. ELQ-596 attenuates babesiosis in immunosuppressed mice [1].Formula:C24H17ClF3NO3Colore e forma:SolidPeso molecolare:459.84UCB7362
CAS:UCB7362 (GLXC-26743) is an orally available and potent plasmepsin X (PMX) inhibitor with anti-malarial activity.UCB7362 inhibits parasite reproduction.Formula:C25H26ClN5O3Purezza:97.67%Colore e forma:SolidPeso molecolare:479.96Propamidine
CAS:Propamidine acts as a covalent inhibitor of TMPRSS2 and exhibits antibacterial properties. [1]Formula:C17H20N4O2Purezza:98%Colore e forma:SolidPeso molecolare:312.37EDI048
CAS:EDI048, also known as compound 1.16, is an orally active inhibitor of Cryptosporidium PI4K, utilized in the study of cryptosporidiosis [1].Formula:C25H21ClN4O4Purezza:98%Colore e forma:SolidPeso molecolare:476.91BTG 502
CAS:BTG 502 is an alkylamide insecticide that binds to voltage-gated sodium channels, antagonising the activation of sodium channels by Batrachotoxin (BTX).Formula:C21H24BrNOPurezza:99.30%Colore e forma:SolidPeso molecolare:386.33Antileishmanial agent-23
CAS:Antileishmanial agent-23 (compound G1/9), a potent and selective trypanothione reductase (TR) inhibitor, exhibits an IC50 of 2.24 ± 0.52 μM.Formula:C20H17N3O4S2Purezza:98%Colore e forma:SolidPeso molecolare:427.5Eugenitin
CAS:Eugenitin, a polyketide from Mycoleptodiscus indicus, exhibits inhibitory activity against Leishmania major with an LD50 of 39.9 μM and demonstrates lowFormula:C12H12O4Purezza:98%Colore e forma:SolidPeso molecolare:220.22OfChi-h-IN-2
CAS:OfChi-h-IN-2 (compound TQ19) is a potent inhibitor of OfChi-h, exhibiting a K i of 0.33 μM, and significantly impairs the growth and development of OstriniaFormula:C25H28ClN5O3Purezza:98%Colore e forma:SolidPeso molecolare:481.98FIKK9.1-IN-1
CAS:FIKK9.1-IN-1 (Compound 1), an antimalarial agent (IC50: 2.68 μg/mL), serves as a FIKK9.1 inhibitor by interacting with the ATP-binding residues within FIKK9.1,Formula:C22H22N2SePurezza:98%Colore e forma:SolidPeso molecolare:393.38Z-Pro-Pro-CHO
CAS:Z-Pro-Pro-CHO acts as a prolyl oligopeptidase inhibitor with half-maximal inhibitory concentrations (IC50) of 0.16 μM for human prolyl oligopeptidase and 0.01Formula:C18H22N2O4Purezza:98%Colore e forma:SolidPeso molecolare:330.38Fervenulin
CAS:<p>Fervenulin, from Streptomyces sp. CMU-MH021, halts egg hatch (MIC: 30 μg/mL) and kills J2 larvae (MIC: 120 μg/mL) of M. incognita.</p>Formula:C7H7N5O2Purezza:99.75%Colore e forma:SolidPeso molecolare:193.16Myrrhterpenoid O
CAS:Unfortunately, you did not provide the description of the chemical compound that needs to be rewritten.Formula:C16H20O3Purezza:98%Colore e forma:SolidPeso molecolare:260.33SID 26681509
CAS:SID 26681509 is a selective, reversible and competitive human cathepsin L inhibitor (IC50 of 56 nM).Formula:C27H33N5O5SPurezza:99.18%Colore e forma:SolidPeso molecolare:539.65Ref: TM-T12909
1mg66,00€5mg144,00€10mg216,00€25mg437,00€50mg652,00€100mg930,00€1mL*10mM (DMSO)172,00€Dehydroemetine
CAS:Dehydroemetine, a synthetic emetine, treats amoebic infections and leishmaniasis, and resists metronidazole amoebiosis.Formula:C29H38N2O4Purezza:98.68% - 99.68%Colore e forma:SolidPeso molecolare:478.62GSK3186899
CAS:GSK3186899 is an inhibitor of Cdc2-related kinase 12 with an EC50 of 1.4 μM for L. donovani.Formula:C19H28F3N7O3SPurezza:98.35% - 99.61%Colore e forma:SolidPeso molecolare:491.53ZY-19489
CAS:<p>ZY-19489: Antimalarial, potential single-dose cure, FDA orphan drug status.</p>Formula:C24H32FN9Purezza:>99.99%Colore e forma:SoildPeso molecolare:465.57CWHM-1552
CAS:CWHM-1552 is an effective Plasmodium falciparum inhibitor. For the 3D7 and Dd2 strains, the IC50s are 51 nM and 53 nM.Formula:C22H27F2N3OPurezza:99.56%Colore e forma:SolidPeso molecolare:387.47MMV688533
CAS:MMV688533 has antimalarial activity.Formula:C24H15F6N5O2Purezza:99.12%Colore e forma:SoildPeso molecolare:519.4Ref: TM-T67695
1mg185,00€5mg409,00€10mg605,00€25mg938,00€50mg1.293,00€100mg1.738,00€500mg3.496,00€1mL*10mM (DMSO)509,00€Noracronycine
CAS:Noracronycine is an alkaloid originally isolated from G. pentaphylla, known for its antimalarial activity. It is effective against P. yoelii at a concentration of 10 μg/mL.Formula:C19H17NO3Peso molecolare:307.34PFK-IN-1
CAS:PFK-IN-1 (compound 1) is an inhibitor of 6-phosphofructo-1-kinase (PFK), demonstrating IC50 values of 0.41 and 0.23 μM against T. brucei and T. cruzi PFK, respectively, and an ED50 of 15.18 μg/mL for T. brucei. The compound has a half-life of 9.7 minutes in rat liver microsomes and 408 minutes in mouse liver microsomes.Formula:C18H15Cl2N3O4SColore e forma:SolidPeso molecolare:440.3Antimalarial agent 48
CAS:<p>Antimalarial agent 48 (Compound 15a) is a triazine compound with antimalarial activity, showing effectiveness against Plasmodium falciparum K1 and Plasmodium falciparum FCR3 with IC50 values of 280 and 290 nM, respectively. It holds promise for research in the field of anti-infective treatments.</p>Formula:C19H14F3N11Colore e forma:SolidPeso molecolare:453.383Insecticidal agent 16
CAS:Insecticidal agent 16 (compound A21) exhibits insecticidal activity against Plutella xylostella, with LC50 values of 1.2 and 13.2 µg/mL respectively.Formula:C21H13Cl2F6N5O2SColore e forma:SolidPeso molecolare:584.32LN002
CAS:LN002 is an orally active inhibitor of Cryptosporidium oxidase, utilized for research in cryptosporidiosis.Formula:C22H15N7Colore e forma:SolidPeso molecolare:377.40SAL-0010042
CAS:SAL-0010042 is an inhibitor of Plasmodium phosphodiesterase β (PDEβ), effectively blocking the hydrolysis of cAMP and cGMP in gametocytes with an IC50 of 48.9 nM, thereby activating PKG and inhibiting the growth and development of Plasmodium (IC50s for 3D7 and Dd2 are 142 nM and 218 nM, respectively). It also inhibits hPDE5 and hPDE6 with IC50 values of 632 nM and 73 nM, respectively.Formula:C15H15FN4OColore e forma:SolidPeso molecolare:286.304Ferrocene
CAS:Ferrocene, a crucial structural core in bioorganometallic chemistry, is renowned for its intrinsic stability, excellent oxygen reduction capabilities, and low toxicity. It also exhibits antimalarial and anticancer properties.Formula:C10H10FeColore e forma:SolidPeso molecolare:186.03WR-27653
CAS:WR-27653 (RC-12), a derivative of Catechol, demonstrates significant activity against hypnozoites in the Plasmodium cynomolgi-Rhesus monkey (Macaca mulatta) model, which is considered the gold standard. Additionally, WR-27653 exhibits antimalarial properties.Formula:C20H36BrN3O2Colore e forma:SolidPeso molecolare:430.423MED6-189
CAS:MED6-189, an analog of kalihinol, disrupts the apicoplast functions and vesicular transport in the malignant malaria parasite (P. falciparum, IC50 < 50 nM). The compound specifically targets the apicoplast, which is a non-photosynthetic plastid essential for isoprenoid synthesis, found in most apicomplexan parasites.Formula:C17H26N2OColore e forma:SolidPeso molecolare:274.40Ipronidazole
CAS:Ipronidazole (RO-71554) is an orally effective antiprotozoal agent used to prevent and ameliorate histomoniasis in turkeys, commonly referred to as blackhead disease.Formula:C7H11N3O2Colore e forma:SolidPeso molecolare:169.18SLU-10906
CAS:SLU-10906 (Compound 63) is an orally active inhibitor of Cryptosporidium. It demonstrates activity against the parasite in cell-based infection models with an EC50 of 0.19 μM and exhibits no cytotoxicity. SLU-10906 is a promising candidate for research in cryptosporidiosis.Formula:C22H21BFN5O2Colore e forma:SolidPeso molecolare:417.244SPB07935
CAS:SPB07935 inhibits plasmepsin II in the malaria-causing parasite Plasmodium falciparum and serves as an antimalarial agent. It affects the life cycle of P. falciparum, hindering the growth of the parasite's FcB1 and 3D7 strains, with IC50 values of 8 μM and 4.7 μM, respectively.Formula:C22H15N5O4S2Colore e forma:SolidPeso molecolare:477.516PIQ-2
CAS:PIQ-2 (compound 54) serves as an antiprotozoal agent, displaying potent activity against IP. falciparum 3D7 and B. divergens Rouen, with IC50 values of 9.4 nM and 1.6 nM, respectively.Formula:C23H21F3N4O3Colore e forma:SolidPeso molecolare:458.43NEU-1017
CAS:NEU-1017 serves as a broad-spectrum antiparasitic compound, effectively inhibiting T. brucei, L. major, and P. falciparum with EC50 values of 210 nM, 240 nM, and 3 nM, respectively.Formula:C33H31ClFN5O3SColore e forma:SolidPeso molecolare:632.147Menoctone
CAS:Menoctone is an orally effective antimalarial agent that inhibits blood-induced rodent malaria. It enhances the antimalarial effects of chloroquine or quinine, making it useful for malaria research.Formula:C24H32O3Colore e forma:SolidPeso molecolare:368.51MMV03
CAS:<p>MMV03 is an antimalarial compound effective against Plasmodium falciparum, with an EC50 of 0.6 μM.</p>Formula:C19H14N4OSColore e forma:SolidPeso molecolare:346.406Etofamide
CAS:Etofamide, an antimicrobial agent, exhibits an IC50 of 5.96 mg/L against amoebae.Formula:C19H20Cl2N2O5Colore e forma:SolidPeso molecolare:427.28Arohynapene B
CAS:Arohynapene B is an anticoccidial compound that inhibits the growth of Eimeria parasites.Formula:C18H22O3Colore e forma:SolidPeso molecolare:286.3662-Phenazinamine,N,5-bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-
CAS:Formula:C27H22Cl2N4Purezza:98%Colore e forma:SolidPeso molecolare:473.39641-Hexadecylphosphorylcholine
CAS:<p>Treatment for leishmaniasis</p>Formula:C21H46NO4PPurezza:Min 98%Colore e forma:White PowderPeso molecolare:407.57 g/molInsecticidal agent 6
CAS:<p>Compound Im (Insecticidal agent 6) is a potent inhibitor of insect ryanodine receptors (RyRs), exhibiting an EC50 of 0.6308 µM against S.</p>Formula:C19H14BrCl2N5O4Purezza:98%Colore e forma:SolidPeso molecolare:527.16
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