Antiparassitari
Gli antiparassitari sono composti progettati per trattare e prevenire le infezioni parassitarie inibendo la crescita e la sopravvivenza dei parassiti. Questa categoria include una gamma di agenti antiparassitari destinati esclusivamente all'uso in laboratorio e non per il consumo umano. Questi prodotti sono essenziali per scopi di ricerca, consentendo agli scienziati di studiare i cicli di vita dei parassiti, i meccanismi d'azione e lo sviluppo della resistenza. L'uso di antiparassitari in ambienti di laboratorio aiuta nella scoperta e nell'ottimizzazione di nuovi trattamenti per le malattie parassitarie, contribuendo ai progressi nella parassitologia medica e veterinaria. I ricercatori si affidano a questi prodotti per migliorare la comprensione delle infezioni parassitarie e sviluppare terapie più efficaci.
Trovati 704 prodotti di "Antiparassitari"
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Diethyl Isobutylmalonate
CAS:Prodotto controllato<p>Applications Diethyl Isobutylmalonate is used as a reagent in the synthesis of quinoline-based zinc metallo-aminopeptidase inhibitors which have antimalarial activity.<br>References Flipo, M., et al.: Bioorg. Med. Chem. Lett., 13, 2659 (2003)<br></p>Formula:C11H20O4Colore e forma:NeatPeso molecolare:216.275-Nitro-1H-quinolin-2-one
CAS:Prodotto controllato<p>Applications 5-Nitro-1H-quinolin-2-one is used in the synthetic preparation of novel antileishmanial agents for Leishmania donovani promastigotes.<br>References Paloque, L., et al.: Europ. J. Med. Chem., 54, 75 (2012);<br></p>Formula:C9H6N2O3Colore e forma:NeatPeso molecolare:190.163-Chloro-N-(3-methoxyphenyl)propanamide
CAS:Prodotto controllato<p>Applications 3-Chloro-N-(3-methoxyphenyl)propanamide acts as an inhibitor towards DOXP-reductoisomerase (DXR), a primary target for antimalarial drugs.<br>References Bodill, T. et al.: Bioorg. Med. Chem., 21, 4332 (2013);<br></p>Formula:C10H12ClNO2Colore e forma:NeatPeso molecolare:213.6623-Des(methoxyimino)-23-hydroxy Moxidectin O-TBS
CAS:Prodotto controllatoFormula:C42H66O8SiColore e forma:NeatPeso molecolare:727.054-(Aminomethyl)-cyclohexanone Hydrochloride
CAS:Prodotto controllato<p>Applications 4-(Aminomethyl)-cyclohexanone Hydrochloride is used to prepare dispiro-1,2,4-trioxolanes with antimalarial activities. It is also used to synthesize aminopyrimidines as SYK inhibitors useful in the treatment of SYK-mediated diseases.<br>References Tang, Y., et al.: Bioorg. Med. Chem. Lett., 17, 1260 (2007); Altman, M., et al.: PCT Int. Appl. (2011), WO 2011075515 A1 20110623<br></p>Formula:C7H13NO·HClColore e forma:NeatPeso molecolare:127.18 + 36.463-Aminopropionitrile (Stabilized with K2CO3)
CAS:Prodotto controllatoFormula:C3H6N2Colore e forma:NeatPeso molecolare:70.09Pseurotin A
CAS:Prodotto controllato<p>Applications Pseurotin A shows antiparasitic and anticancer activity. It exhibits inhibition towards IgE (immunoglobin E) production.<br>References Martinez-Luis, S. et al.: Nat. Prod. Comm., 7, 165 (2012); Bioorg. Med. Chem. Lett., 19, 1457 (2009);<br></p>Formula:C22H25NO8Colore e forma:NeatPeso molecolare:431.444-Methoxy-6-(2-phenylethyl)-2H-pyran-2-one
CAS:Prodotto controllato<p>Applications 4-Methoxy-6-(2-phenylethyl)-2H-pyran-2-one is a Kawain (K145490) derivative that is known to exhibit antimalarial and antituberculosis activities. 4-Methoxy-6-(2-phenylethyl)-2H-pyran-2-one has been identified as a lead compound for the dual treatment of malaria and leishmaniasis.<br>References McCracken, S.T., et al.: Bioorg. Med. Chem., 20, 1482 (2012); Elzaawely, A.A.. et al.: Food. Chem., 103, 486 (2007); Xuan, T.D., et al.: J. Natural. Med., 62, 188 (2008);<br></p>Formula:C14H14O3Colore e forma:NeatPeso molecolare:230.262'-O-(2-Methoxyethyl)-5-methylcytidine (~90%)
CAS:Prodotto controllatoFormula:C13H21N3O6Purezza:~90%Colore e forma:NeatPeso molecolare:315.324,4'-Dimethyldiphenylamine
CAS:Prodotto controllato<p>Applications 4,4'-Dimethyldiphenylamine is a reagent used in the comparative studies of the analgesic and anti-inflammatory properties of N-phenylanthranilic acids and mefenamic acid, and the anti parasitic activities of some substituted diphenylamines.<br>References Izard-Verchere, C., et al.: Chimica Therapeutica, 6, 346 (1971)<br></p>Formula:C14H15NColore e forma:NeatPeso molecolare:197.282-Hydroxy-1-methyl-9,10-anthracenedione
CAS:Prodotto controllatoFormula:C15H10O3Colore e forma:NeatPeso molecolare:238.242,5-Diacetoxy-2,5-dihydrofuran (Mixture of Isomers) (>90%)
CAS:Prodotto controllato<p>Applications 2,5-Diacetoxy-2,5-dihydrofuran is used as a reagent to synthesize Mexicanin H, a biologically active sesquiterpene lactone that exhibits antiparasitic activity against Trypanosoma cruzi (a parasite that causes Chagas disease)<br>References Jimenez-Ortiz, V., et al.: Parasitology, 91, 170 (2005); Romo, J., et al.: Tetrahedron Lett., No vol. given, 1029 (1966)<br></p>Formula:C8H10O5Purezza:>90%Colore e forma:NeatPeso molecolare:186.16PBD-5,11-dione
CAS:Prodotto controllato<p>Applications PBD-5,11-dione (cas# 18877-34-4) is a useful research chemical.<br></p>Formula:C12H12N2O2Colore e forma:NeatPeso molecolare:216.243-[(Dimethylamino)methyl]-2-hexanone
CAS:Prodotto controllatoFormula:C9H19NOColore e forma:ColourlessPeso molecolare:157.25Benzenebutanoic Acid Ethyl Ester
CAS:Prodotto controllato<p>Applications Benzenebutanoic Acid Ethyl Ester is used in the synthesis of thiazolium salts with potent antimalarial activity. Also used in the preparation of novel lactate dehydrogenase A inhibitors. This compound is suitable for lactate dehydrogenase (LDH) related research.<br>References Hamze, A. et al.: J. Med. Chem., 48, 3639 (2005); Ward, R. et al.: J. Med. Chem., 55, 3285 (2012);<br></p>Formula:C12H16O2Colore e forma:NeatPeso molecolare:192.25Tizoxanide - 98%
CAS:<p>Anti-parasitic; pyruvate ferredoxin oxidoreductase inhibitor</p>Formula:C10H7N3O4SPurezza:Min. 95%Peso molecolare:265.01573Oxfendazole
CAS:<p>Oxfendazole is a benzimidazole anthelmintic with action on microtubule formation in parasitic worms and is used for treating gastrointestinal parasites in livestock.</p>Formula:C15H13N3O3SPurezza:Min. 98 Area-%Colore e forma:White PowderPeso molecolare:315.35 g/molAmoscanate
CAS:<p>Amoscanate is an antischistosomal agent, which is a synthetic compound with a broad spectrum of activity against parasitic infections. Its mode of action involves the disruption of parasite metabolism and structure, ultimately leading to the elimination of schistosomes. Schistosomes are trematode worms responsible for schistosomiasis, a significant parasitic disease affecting millions of people worldwide.</p>Formula:C13H9N3O2SPurezza:Min. 95%Peso molecolare:271.3 g/molIvermectin
CAS:<p>Naturally produced by the soil bacterium Streptomyces avermitili, it is clinically used in the treatment of parasitosis in both humans and animals. Ivermectin is commercially available as a mixture of 80% 22, 23-dihydroavermectin B1a and 20% 22, 23-dihydroavermectin B1b. In 2020, Ivermectin indicated that it was a good antiviral agent in the treatment of SARS-CoV-2 and a new mechanism of action has been suggested. Ivermectin would act on importin α/β heterodimer and affect nuclear transport and the translocation of viral proteins.</p>Formula:C48H74O14Purezza:85%MinPeso molecolare:875.1 g/mol4′-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethylavermectin A1a
CAS:<p>4′-O-De(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-5-O-demethylavermectin A1a is a semi-synthetic derivative of avermectin, which is a naturally occurring compound isolated from the fermentation broth of the soil bacterium *Streptomyces avermitilis*. This compound exhibits potent antiparasitic activity by targeting the glutamate-gated chloride channels in the nervous systems of parasitic organisms. By binding and activating these channels, it increases the permeability of the cell membrane to chloride ions, resulting in paralysis and death of the parasite.</p>Formula:C41H60O11Purezza:Min. 95%Peso molecolare:728.91 g/molPF 1022A
CAS:<p>PF 1022A is a cyclooctadepsipeptide, which is a type of cyclic peptide composed of amino acids and hydroxy acids. It is derived from the fermentation products of the fungus *Mycelia sterilia*, a member of the *Rosellinia* genus. Its mode of action involves disrupting glutamate-gated chloride channels in parasitic nematodes, which leads to paralysis and eventual death of the parasite.</p>Formula:C52H76N4O12Purezza:Min. 95%Peso molecolare:949.18 g/molHalofuginone
CAS:<p>Halofuginone (RU-19110) inhibits prolyl-tRNA synthetase (Ki=18.3 nM), down-regulates Smad3, and blocks TGF-β at 10 ng/ml.</p>Formula:C16H17BrClN3O3Purezza:99.53%Colore e forma:Off-White SolidPeso molecolare:414.68Satranidazole
CAS:<p>Satranidazole is an antimicrobial agent that falls under the category of synthetic nitroimidazoles. It is derived from chemical synthesis and is designed to combat infections caused by specific organisms. The mode of action involves the reduction of the nitro group within the organism, creating reactive intermediates that disrupt DNA synthesis and lead to cell death. This mode of action is notably effective against protozoal infections and anaerobic bacterial infections.</p>Formula:C8H11N5O5SPurezza:Min. 95%Peso molecolare:289.27 g/molICA
CAS:<p>ICA (N-[4-(2-Pyridinyl)-2-thiazolyl]-2-pyridinamine) is a SK channel inhibitor and exhibits antileishmanial activity (IC50: 2.1 µM).</p>Formula:C13H10N4SPurezza:99.68%Colore e forma:SolidPeso molecolare:254.31Piperaquine
CAS:<p>Piperaquine is a bisquinoline antimalarial compound and a companion compound to artemisinin.</p>Formula:C29H32Cl2N6Purezza:98%Colore e forma:SolidPeso molecolare:535.51BPH-715
CAS:<p>BPH-715 inhibits the liver-stage growth of P. falciparum with an IC50 of 10 μM for P. falciparum exoerythrocytic forms in HepG2 cells.</p>Formula:C17H31NO7P2Purezza:98.91%Colore e forma:SolidPeso molecolare:423.38Quinfamide
CAS:<p>Quinfamide is a compound with the potential to treat tropical parasitic infections such as Amoebiasis and Helminthiasis.</p>Formula:C16H13Cl2NO4Purezza:99.92%Colore e forma:SolidPeso molecolare:354.18Halofuginone hydrobromide
CAS:<p>Halofuginone specifically inhibits collagen type I and MMP-2 gene expression, which may result in the suppression of angiogenesis and tumor cell growth.</p>Formula:C16H17BrClN3O3·HBrPurezza:97.01% - 99.73%Colore e forma:SolidPeso molecolare:495.59Antimalarial agent 26
CAS:<p>Antimalarial agent 26, a derivative of 1,4-naphthoquinones, demonstrates antimalarial properties through oral administration.</p>Formula:C20H22N4O3Purezza:98%Colore e forma:SolidPeso molecolare:366.41Antiparasitic agent-18
CAS:<p>Antiparasitic agent-18 (compound 3a) exhibits potent and selective antiprotozoal activity, demonstrating effective inhibition of T.</p>Formula:C25H21N7OPurezza:98%Colore e forma:SolidPeso molecolare:435.48Antimalarial agent 19
CAS:<p>Compound 6e, an antimalarial, targets P. falciparum K1 (EC50 0.3 µM) and P. berghei (EC50 15.3 µM); has high solubility and stability.</p>Formula:C22H33Cl2N5SPurezza:98%Colore e forma:SolidPeso molecolare:470.5Antimalarial agent 24
CAS:<p>Compound 24 (Compound 7), an in vitro antimalarial agent, demonstrates inhibitory activity against the Plasmodium falciparum W2 strain with an IC50 of 0.81 μM</p>Formula:C20H16N4O2Purezza:98%Colore e forma:SolidPeso molecolare:344.37Antimalarial agent 29
CAS:<p>Compound 29 (also known as Compound 16) is an antimalarial agent that demonstrates inhibition of the P.</p>Formula:C18H10ClF3N2Purezza:98%Colore e forma:SolidPeso molecolare:346.73Antileishmanial agent-14
CAS:<p>Antileishmanial agent-14, a sulfuretin analog, exhibits potential activity against Leishmania donovani promastigotes (IC 50 = 4.1 μM) and inhibits infection by</p>Formula:C23H26ClNO5Purezza:98%Colore e forma:SolidPeso molecolare:431.91Insecticidal agent 2
CAS:<p>Insecticidal agent 2 (example 2) is an effective pesticide that significantly inhibits pest growth [1].</p>Formula:C16H8ClF7N2O2Purezza:98%Colore e forma:SolidPeso molecolare:428.69Antileishmanial agent-15
CAS:<p>Antileishmanial agent-15 (compound 13c) exhibits potent activity against L.</p>Formula:C28H39N5O4Purezza:98%Colore e forma:SolidPeso molecolare:509.64Epsiprantel
CAS:<p>Epsiprantel is an orally active antiparasitic drug that inhibits various tapeworms, including Echinococcus granulosus (granular echinococcus), in dogs.</p>Formula:C20H26N2O2Purezza:98.09%Colore e forma:SolidPeso molecolare:326.43CRK12-IN-2
CAS:<p>CRK12-IN-2, a potent CRK12 inhibitor, has EC50 of 3.2 nM for T. congolense and 0.08 nM for T. vivax; treats trypanosomiasis in animals.</p>Formula:C23H33F2N5O3S2Purezza:99.26% - 99.70%Colore e forma:SolidPeso molecolare:529.67Symetine
CAS:<p>Symetine（L 16726） is a small molecule compound with antiparasitic activity that can be used to study amoebic liver abscesses in guinea pigs.</p>Formula:C30H48N2O2Purezza:99.79%Colore e forma:SolidPeso molecolare:468.71(Rac)-ACT-451840
CAS:<p>(Rac)-ACT-451840 is an isomer of ACT-451840 exhibiting antimalarial activity against Plasmodium falciparum NF54.</p>Formula:C47H54N6O3Purezza:99.25%Colore e forma:SolidPeso molecolare:750.97Chalcone 4 hydrate
CAS:<p>Chalcone 4 hydrate, an anti-parasite compound, inhibits the growth of Theileria and Babesia.</p>Formula:C16H15ClO4Purezza:99.54%Colore e forma:SolidPeso molecolare:306.74Phosphodiesterase-IN-1
CAS:<p>Phosphodiesterase-IN-1 (Compound 7), a phosphodiesterase (PDE) inhibitor, exhibits anti-Plasmodium and antiproliferative activities. It effectively inhibits P. falciparum (strain 3D7) with an IC 50 value of 0.64 μM [1].</p>Formula:C15H15FN4OColore e forma:SolidPeso molecolare:286.3MMV006833
CAS:<p>MMV006833 is an inhibitor of Plasmodium falciparum. It targets the lipid transfer protein PfSTART1, inhibiting the ring-stage development of Plasmodium falciparum.</p>Formula:C19H27ClN2O4SColore e forma:SolidPeso molecolare:414.95Topoisomerase II inhibitor 16
CAS:<p>Topoisomerase II Inhibitor 16 (compound CT3) is a selective, orally bioavailable, and irreversible inhibitor of trypanosomal topoisomerase II, possessing the</p>Formula:C19H12F4N6OPurezza:98%Colore e forma:SolidPeso molecolare:416.33SQ109
CAS:<p>SQ109 (NSC-722041) is an effective inhibitor of the trypomastigote form of the parasite (IC50 = 50 nM). SQ109 is an antitubercular agent and targets MmpL3.</p>Formula:C22H38N2Purezza:99.70% - 99.91%Colore e forma:SolidPeso molecolare:330.55Antitrypanosomal agent 2
CAS:<p>Antitrypanosomal agent 2 shows potent and specific antiparasite activities against Trypanosoma brucei.</p>Formula:C17H13N5O3Purezza:99.2%Colore e forma:SolidPeso molecolare:335.32Artelinic acid
CAS:<p>Artelinic acid is an artemisinin analog with antimalarial activity and is used for the treatment of multi-drug resistant strains of Plasmodium falciparum.</p>Formula:C23H30O7Purezza:97.49% - 97.69%Colore e forma:SolidPeso molecolare:418.48Bithionol sulfoxide
CAS:<p>Bithionol sulfoxide (Bithionoloxide) is a compound with inhibitory effects against parasites, inhibiting Fasciola hepatica and Schistosoma mansoni.</p>Formula:C12H6Cl4O3SPurezza:98.76%Colore e forma:Off White To Tinch Pink Crystalline PowderPeso molecolare:372.05Rufigallol
CAS:<p>Rufigallol, an anthraquinone with six OH groups, induces DLC and fluoresces when aggregated, showing antimalarial effects with vitamin C and ketones.</p>Formula:C14H8O8Purezza:98.92% - 99.27%Colore e forma:SolidPeso molecolare:304.21
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