Antiparassitari
Gli antiparassitari sono composti progettati per trattare e prevenire le infezioni parassitarie inibendo la crescita e la sopravvivenza dei parassiti. Questa categoria include una gamma di agenti antiparassitari destinati esclusivamente all'uso in laboratorio e non per il consumo umano. Questi prodotti sono essenziali per scopi di ricerca, consentendo agli scienziati di studiare i cicli di vita dei parassiti, i meccanismi d'azione e lo sviluppo della resistenza. L'uso di antiparassitari in ambienti di laboratorio aiuta nella scoperta e nell'ottimizzazione di nuovi trattamenti per le malattie parassitarie, contribuendo ai progressi nella parassitologia medica e veterinaria. I ricercatori si affidano a questi prodotti per migliorare la comprensione delle infezioni parassitarie e sviluppare terapie più efficaci.
Trovati 711 prodotti di "Antiparassitari"
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Insecticidal agent 2
CAS:Insecticidal agent 2 (example 2) is an effective pesticide that significantly inhibits pest growth [1].Formula:C16H8ClF7N2O2Purezza:98%Colore e forma:SolidPeso molecolare:428.69UCT943
CAS:UCT943 is an inhibitor of Plasmodium falciparum PI4K (IC50 = 23 nM).Formula:C22H20F3N5OPurezza:99.87%Colore e forma:SolidPeso molecolare:427.42Ref: TM-T13246
1mg99,00€2mg149,00€5mg245,00€1mL*10mM (DMSO)264,00€10mg355,00€25mg572,00€50mg772,00€100mg1.035,00€500mg2.080,00€Allopurinol riboside
CAS:Allopurinol riboside, an allopurinol metabolite, inhibits purine nucleoside phosphorylase in parasites with a Ki of 277 μM.Formula:C10H12N4O5Purezza:99.46% - 99.73%Colore e forma:SolidPeso molecolare:268.23Artelinic acid
CAS:Artelinic acid is an artemisinin analog with antimalarial activity and is used for the treatment of multi-drug resistant strains of Plasmodium falciparum.Formula:C23H30O7Purezza:97.49% - 97.69%Colore e forma:SolidPeso molecolare:418.48Ref: TM-T10378
1mg63,00€5mg138,00€1mL*10mM (DMSO)172,00€10mg215,00€25mg403,00€50mg627,00€100mg892,00€Brotianide
CAS:Brotianide (BAY-VA4059) has anthelmintic activity and is highly potent against liver fluke and gastric fluke infestations and can be used to treat acute,Formula:C15H10Br2ClNO2SPurezza:97.44% - 98.14%Colore e forma:SolidPeso molecolare:463.57Rufigallol
CAS:Rufigallol, an anthraquinone with six OH groups, induces DLC and fluoresces when aggregated, showing antimalarial effects with vitamin C and ketones.
Formula:C14H8O8Purezza:98.92% - 99.27%Colore e forma:SolidPeso molecolare:304.21Bithionol sulfoxide
CAS:Bithionol sulfoxide (Bithionoloxide) is a compound with inhibitory effects against parasites, inhibiting Fasciola hepatica and Schistosoma mansoni.Formula:C12H6Cl4O3SPurezza:98.76%Colore e forma:Off White To Tinch Pink Crystalline PowderPeso molecolare:372.05AP-C5
CAS:AP-C5 inhibits cGKII with a Pic50 of 7.2, useful in diarrheal disease research.Formula:C16H13N5Purezza:99.82%Colore e forma:SolidPeso molecolare:275.31Antimalarial agent 30
CAS:Antimalarial agent 30 has anti-Plasmodium berghei liver stage parasite activity and antimalarial activity for the study of malarial infections.Formula:C18H11F3N2Purezza:99.83% - 99.90%Colore e forma:SolidPeso molecolare:312.29JCP174
CAS:JCP174 is a depalmitoylase inhibitor that enhances Toxoplasma host-cell invasion by targeting TgPPT1.Formula:C12H12ClNO3Purezza:97.05%Colore e forma:SolidPeso molecolare:253.68Ref: TM-T25549
1mg66,00€1mL*10mM (DMSO)129,00€5mg150,00€10mg207,00€25mg310,00€50mg419,00€100mg567,00€200mg743,00€Fervenulin
CAS:Fervenulin, from Streptomyces sp. CMU-MH021, halts egg hatch (MIC: 30 μg/mL) and kills J2 larvae (MIC: 120 μg/mL) of M. incognita.Formula:C7H7N5O2Purezza:99.75%Colore e forma:SolidPeso molecolare:193.16Ref: TM-T15277
1mg71,00€1mL*10mM (DMSO)111,00€5mg136,00€10mg210,00€25mg358,00€50mg500,00€100mg665,00€200mg893,00€Phylloflavan
CAS:Phylloflavan, an antileishmanial compound, exhibits an intracellular half maximal effective concentration (EC50) of 3.2 nM in RAW 264.7 cells and inhibits theFormula:C26H26O10Purezza:98%Colore e forma:SolidPeso molecolare:498.48DDD85646
CAS:DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.Formula:C21H24Cl2N6O2SPurezza:97.8% - 99.76%Colore e forma:SolidPeso molecolare:495.43Ref: TM-T27135
1mg90,00€5mg253,00€1mL*10mM (DMSO)275,00€10mg379,00€25mg640,00€50mg892,00€100mg1.224,00€Antileishmanial agent-23
CAS:Antileishmanial agent-23 (compound G1/9), a potent and selective trypanothione reductase (TR) inhibitor, exhibits an IC50 of 2.24 ± 0.52 μM.Formula:C20H17N3O4S2Purezza:98%Colore e forma:SolidPeso molecolare:427.5SID 26681509
CAS:SID 26681509 is a selective, reversible and competitive human cathepsin L inhibitor (IC50 of 56 nM).Formula:C27H33N5O5SPurezza:99.18%Colore e forma:SolidPeso molecolare:539.65Ref: TM-T12909
1mg63,00€5mg137,00€1mL*10mM (DMSO)163,00€10mg205,00€25mg414,00€50mg618,00€100mg882,00€Eugenitin
CAS:Eugenitin, a polyketide from Mycoleptodiscus indicus, exhibits inhibitory activity against Leishmania major with an LD50 of 39.9 μM and demonstrates lowFormula:C12H12O4Purezza:98%Colore e forma:SolidPeso molecolare:220.22Antileishmanial agent-17
CAS:Antileishmanial agent-17, a coumarin hybrid, exhibits potent antileishmanial activity (IC50 <0.78 μM) while proving non-toxic to normal VERO cells.Formula:C27H37N5O5Purezza:98%Colore e forma:SolidPeso molecolare:511.61OfChi-h-IN-2
CAS:OfChi-h-IN-2 (compound TQ19) is a potent inhibitor of OfChi-h, exhibiting a K i of 0.33 μM, and significantly impairs the growth and development of OstriniaFormula:C25H28ClN5O3Purezza:98%Colore e forma:SolidPeso molecolare:481.98Antileishmanial agent-16
CAS:Antileishmanial agent-16 (compound 14c), an anti-Leishmania agent, exhibits potent activity against Leishmania major promastigotes (IC50 = 0.59 µM) andFormula:C27H37N5O4Purezza:98%Colore e forma:SolidPeso molecolare:495.61UCB7362
CAS:UCB7362 (GLXC-26743) is an orally available and potent plasmepsin X (PMX) inhibitor with anti-malarial activity.UCB7362 inhibits parasite reproduction.Formula:C25H26ClN5O3Purezza:97.67%Colore e forma:SolidPeso molecolare:479.96Propamidine
CAS:Propamidine acts as a covalent inhibitor of TMPRSS2 and exhibits antibacterial properties. [1]Formula:C17H20N4O2Purezza:98%Colore e forma:SolidPeso molecolare:312.37FIKK9.1-IN-1
CAS:FIKK9.1-IN-1 (Compound 1), an antimalarial agent (IC50: 2.68 μg/mL), serves as a FIKK9.1 inhibitor by interacting with the ATP-binding residues within FIKK9.1,Formula:C22H22N2SePurezza:98%Colore e forma:SolidPeso molecolare:393.38Myrrhterpenoid O
CAS:Unfortunately, you did not provide the description of the chemical compound that needs to be rewritten.Formula:C16H20O3Purezza:98%Colore e forma:SolidPeso molecolare:260.33Clazuril
CAS:Clazuril, Anticoccidial drug, inhibits asexual and sexual stages of Eimeria labbeana/E. columbarum, disrupts life cycle.Formula:C17H10Cl2N4O2Colore e forma:SolidPeso molecolare:373.19WAY-309236
CAS:WAY-309236, Inhibits drug-sensitive/resistant Plasmodium falciparum (IC50≈275 nM), bioactive biochemical reagent.Formula:C19H16N4O2Purezza:99.94%Colore e forma:SolidPeso molecolare:332.36Ref: TM-T80832
1mg83,00€5mg175,00€1mL*10mM (DMSO)185,00€10mg282,00€25mg477,00€50mg670,00€100mg929,00€ELQ-596
CAS:ELQ-596, a quinolone derivative, exhibits antimicrobial activity against several protozoan parasites, including the intraerythrocytic parasites Plasmodium and Babesia. ELQ-596 attenuates babesiosis in immunosuppressed mice [1].Formula:C24H17ClF3NO3Colore e forma:SolidPeso molecolare:459.84Z-Pro-Pro-CHO
CAS:Z-Pro-Pro-CHO acts as a prolyl oligopeptidase inhibitor with half-maximal inhibitory concentrations (IC50) of 0.16 μM for human prolyl oligopeptidase and 0.01Formula:C18H22N2O4Purezza:98%Colore e forma:SolidPeso molecolare:330.38BTG 502
CAS:BTG 502 is an alkylamide insecticide that binds to voltage-gated sodium channels, antagonising the activation of sodium channels by Batrachotoxin (BTX).Formula:C21H24BrNOPurezza:99.30%Colore e forma:SolidPeso molecolare:386.33EDI048
CAS:EDI048, also known as compound 1.16, is an orally active inhibitor of Cryptosporidium PI4K, utilized in the study of cryptosporidiosis [1].Formula:C25H21ClN4O4Purezza:98%Colore e forma:SolidPeso molecolare:476.91GSK3186899
CAS:GSK3186899 is an inhibitor of Cdc2-related kinase 12 with an EC50 of 1.4 μM for L. donovani.Formula:C19H28F3N7O3SPurezza:98.35% - 99.61%Colore e forma:SolidPeso molecolare:491.53Dehydroemetine
CAS:Dehydroemetine, a synthetic emetine, treats amoebic infections and leishmaniasis, and resists metronidazole amoebiosis.Formula:C29H38N2O4Purezza:98.68% - 99.68%Colore e forma:SolidPeso molecolare:478.62ZY-19489
CAS:ZY-19489: Antimalarial, potential single-dose cure, FDA orphan drug status.
Formula:C24H32FN9Purezza:>99.99%Colore e forma:SoildPeso molecolare:465.57MMV688533
CAS:MMV688533 has antimalarial activity.Formula:C24H15F6N5O2Purezza:99.12%Colore e forma:SoildPeso molecolare:519.4Ref: TM-T67695
1mg185,00€5mg409,00€1mL*10mM (DMSO)509,00€10mg605,00€25mg938,00€50mg1.293,00€100mg1.738,00€500mg3.496,00€CWHM-1552
CAS:CWHM-1552 is an effective Plasmodium falciparum inhibitor. For the 3D7 and Dd2 strains, the IC50s are 51 nM and 53 nM.Formula:C22H27F2N3OPurezza:99.56%Colore e forma:SolidPeso molecolare:387.47WR-27653
CAS:WR-27653 (RC-12), a derivative of Catechol, demonstrates significant activity against hypnozoites in the Plasmodium cynomolgi-Rhesus monkey (Macaca mulatta) model, which is considered the gold standard. Additionally, WR-27653 exhibits antimalarial properties.Formula:C20H36BrN3O2Colore e forma:SolidPeso molecolare:430.423PFK-IN-1
CAS:PFK-IN-1 (compound 1) is an inhibitor of 6-phosphofructo-1-kinase (PFK), demonstrating IC50 values of 0.41 and 0.23 μM against T. brucei and T. cruzi PFK, respectively, and an ED50 of 15.18 μg/mL for T. brucei. The compound has a half-life of 9.7 minutes in rat liver microsomes and 408 minutes in mouse liver microsomes.Formula:C18H15Cl2N3O4SColore e forma:SolidPeso molecolare:440.3SLU-10906
CAS:SLU-10906 (Compound 63) is an orally active inhibitor of Cryptosporidium. It demonstrates activity against the parasite in cell-based infection models with an EC50 of 0.19 μM and exhibits no cytotoxicity. SLU-10906 is a promising candidate for research in cryptosporidiosis.Formula:C22H21BFN5O2Colore e forma:SolidPeso molecolare:417.244Menoctone
CAS:Menoctone is an orally effective antimalarial agent that inhibits blood-induced rodent malaria. It enhances the antimalarial effects of chloroquine or quinine, making it useful for malaria research.Formula:C24H32O3Colore e forma:SolidPeso molecolare:368.51Insecticidal agent 16
CAS:Insecticidal agent 16 (compound A21) exhibits insecticidal activity against Plutella xylostella, with LC50 values of 1.2 and 13.2 µg/mL respectively.Formula:C21H13Cl2F6N5O2SColore e forma:SolidPeso molecolare:584.32MED6-189
CAS:MED6-189, an analog of kalihinol, disrupts the apicoplast functions and vesicular transport in the malignant malaria parasite (P. falciparum, IC50 < 50 nM). The compound specifically targets the apicoplast, which is a non-photosynthetic plastid essential for isoprenoid synthesis, found in most apicomplexan parasites.Formula:C17H26N2OColore e forma:SolidPeso molecolare:274.40Ipronidazole
CAS:Ipronidazole (RO-71554) is an orally effective antiprotozoal agent used to prevent and ameliorate histomoniasis in turkeys, commonly referred to as blackhead disease.Formula:C7H11N3O2Colore e forma:SolidPeso molecolare:169.18SPB07935
CAS:SPB07935 inhibits plasmepsin II in the malaria-causing parasite Plasmodium falciparum and serves as an antimalarial agent. It affects the life cycle of P. falciparum, hindering the growth of the parasite's FcB1 and 3D7 strains, with IC50 values of 8 μM and 4.7 μM, respectively.Formula:C22H15N5O4S2Colore e forma:SolidPeso molecolare:477.516SAL-0010042
CAS:SAL-0010042 is an inhibitor of Plasmodium phosphodiesterase β (PDEβ), effectively blocking the hydrolysis of cAMP and cGMP in gametocytes with an IC50 of 48.9 nM, thereby activating PKG and inhibiting the growth and development of Plasmodium (IC50s for 3D7 and Dd2 are 142 nM and 218 nM, respectively). It also inhibits hPDE5 and hPDE6 with IC50 values of 632 nM and 73 nM, respectively.Formula:C15H15FN4OColore e forma:SolidPeso molecolare:286.304Ferrocene
CAS:Ferrocene, a crucial structural core in bioorganometallic chemistry, is renowned for its intrinsic stability, excellent oxygen reduction capabilities, and low toxicity. It also exhibits antimalarial and anticancer properties.Formula:C10H10FeColore e forma:SolidPeso molecolare:186.03Antimalarial agent 48
CAS:Antimalarial agent 48 (Compound 15a) is a triazine compound with antimalarial activity, showing effectiveness against Plasmodium falciparum K1 and Plasmodium falciparum FCR3 with IC50 values of 280 and 290 nM, respectively. It holds promise for research in the field of anti-infective treatments.Formula:C19H14F3N11Colore e forma:SolidPeso molecolare:453.383MMV03
CAS:MMV03 is an antimalarial compound effective against Plasmodium falciparum, with an EC50 of 0.6 μM.Formula:C19H14N4OSColore e forma:SolidPeso molecolare:346.406Etofamide
CAS:Etofamide, an antimicrobial agent, exhibits an IC50 of 5.96 mg/L against amoebae.Formula:C19H20Cl2N2O5Colore e forma:SolidPeso molecolare:427.28LN002
CAS:LN002 is an orally active inhibitor of Cryptosporidium oxidase, utilized for research in cryptosporidiosis.Formula:C22H15N7Colore e forma:SolidPeso molecolare:377.40Noracronycine
CAS:Noracronycine is an alkaloid originally isolated from G. pentaphylla, known for its antimalarial activity. It is effective against P. yoelii at a concentration of 10 μg/mL.Formula:C19H17NO3Peso molecolare:307.34PIQ-2
CAS:PIQ-2 (compound 54) serves as an antiprotozoal agent, displaying potent activity against IP. falciparum 3D7 and B. divergens Rouen, with IC50 values of 9.4 nM and 1.6 nM, respectively.Formula:C23H21F3N4O3Colore e forma:SolidPeso molecolare:458.43
